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The map label for this gene is 121637250

Identifier: 121637250

GI number: 121637250

Start: 1509028

End: 1510731

Strand: Reverse

Name: 121637250

Synonym: BCG_1381c

Alternate gene names: NA

Gene position: 1510731-1509028 (Counterclockwise)

Preceding gene: 121637253

Following gene: 121637249

Centisome position: 34.53

GC content: 61.91

Gene sequence:

>1704_bases
ATGCCATCCGAGAAGGCCACCACTCGACACTTGCCAGGGGCCGTCGAGACTCTCAGCCCGCGCACTGGACGACGGCCAGA
GACGCCCGCATACGGCTCATGGCTGCTTGGGCGCGTGTCGGAGAGCCCACGGATGCGGCGGGTACGTATCCAGGGCATGC
TGACCGTCGCCATTTTGGTCACGAACGTGATCGGGCTCATTGTCGGTGCCATGCTACTGACGGTCGCCTTTCCGAAACCA
AGCGTGATTTTGGACGCCCCGCATTGGGTGTCGTTCGGGATCGTTCCGGGATACTGCGTGCTCGCCTTCATACTGGGCAC
CTACTGGCTCACCAGGCAAACGGCTCGAGCGTTGCGGTGGGCAATCGAGGAACGCACCCCCAGCCATGATGAGGCGCGCA
GCGCTTTCCTAGTCCCACTGCGAGTGGCGTTGGCAGTTCTTTTCCTGTGGGGCGCCGCCGCAGCGTTGTGGACGATAATC
TACGGCCTGGCCAACCGGTTGTTTATCCCGCGGTTCCTGTTTTCGATGGGCGTCATCGGCGTTGTCGCAGCCACCAGCTG
CTATCTGTTAACCGAGTTTGCGCTTCGCCCGATGGCCGCCCAGGCGCTCGAAGTGGGAGCAACACCACGATCGCTGGTGC
GAGGCATCGTGGGCCGAACCATGCTGGTGTGGCTGCTCTGTTCAGGCGTACCCAATGTCGGTGTCGCCCTCACCGCCATC
TTCGACGATACGTTTTGGGAACTCTCCAATGATCAATTCATGATCACAGTGCTGATCCTGTGGGCACCACTGTTGATCTT
CGGATTCATCCTGATGTGGATTCTCGCTTGGCTGACGGCCACGCCTGTGCGCGTGGTCCGCGAGGCGCTCAACCGCGTAG
AGCAGGGCGATCTAAGCGGCGATCTGGTCGTATTCGACGGGACCGAACTCGGTGAGCTACAGCGTGGTTTCAACAGAATG
GTCGAGGGCCTGCGCGAGCGCGAACGCGTACGCGATCTCTTCGGCCGCCACGTCGGTCGCGAGGTCGCCGCAGCAGCCGA
ACGCGAGCGACCAAAACTGGGCGGCGAAGAGCGCCATGTCGCCGTCGTCTTCGTCGACATCGTCGGTTCAACTCAATTGG
TCACCAGCCGGCCTGCGGCAGAGGTCGTGATGCTACTCAACCGGTTCTTCACGGTAATCGTCGATGAAGTGAACCATCAC
CGTGGACTTGTCAACAAGTTTCAGGGAGACGCCTCGCTGGCAGTCTTCGGGGCCCCCAACCGCCTGAGCCATCCCGAAGA
TGCCGCGCTGGCCACCGCACGAGCCATCGCCGACCGGCTAGCCAGCGAAATGCCGGAGTGCCAAGCCGGCATCGGGGTAG
CGGCAGGTCAGGTTGTCGCCGGCAATGTCGGCGCCCACGAACGGTTCGAATACACCGTGATCGGCGAACCGGTCAACGAG
GCTGCACGACTGTGCGAACTGGCAAAATCATACCCGAGCCGATTGTTGGCGTCGTCGCAAACGTTGCGCGGTGCCAGTGA
AAACGAATGTGCCCGTTGGTCTTTAGGCGAGACCGTGACACTTCGCGGGCACGACCAGCCCATCCGGCTGGCGTCGCCAG
TTCAACAGCTGCAGATGCCTGCTCAGTCGGCCGACATAGTCGGCGGTGCACTGGGCGATCACCAGACCCACACGATTTAC
CGTGGGGCGCATCCGACAGATTAG

Upstream 100 bases:

>100_bases
GACAGTGCACTGGGCGATGACTAGACGCACCCGACTCACCTTAGAGCGCGCAACGACGTTGTTCCTTAGAGCGTGACCGA
CACACTACGCTGACGTCACC

Downstream 100 bases:

>100_bases
GCTGACGCCACCATGCCGGCGAAAAAGACCATGGCGCAACGCCTGGGCCAGGCACTCGAGACGATGACCCGTCAGTGCGG
CCAGCTGCCCGAGACCCCGG

Product: putative adenylate cyclase

Products: 3',5'-cyclic AMP; diphosphate

Alternate protein names: NA

Number of amino acids: Translated: 567; Mature: 566

Protein sequence:

>567_residues
MPSEKATTRHLPGAVETLSPRTGRRPETPAYGSWLLGRVSESPRMRRVRIQGMLTVAILVTNVIGLIVGAMLLTVAFPKP
SVILDAPHWVSFGIVPGYCVLAFILGTYWLTRQTARALRWAIEERTPSHDEARSAFLVPLRVALAVLFLWGAAAALWTII
YGLANRLFIPRFLFSMGVIGVVAATSCYLLTEFALRPMAAQALEVGATPRSLVRGIVGRTMLVWLLCSGVPNVGVALTAI
FDDTFWELSNDQFMITVLILWAPLLIFGFILMWILAWLTATPVRVVREALNRVEQGDLSGDLVVFDGTELGELQRGFNRM
VEGLRERERVRDLFGRHVGREVAAAAERERPKLGGEERHVAVVFVDIVGSTQLVTSRPAAEVVMLLNRFFTVIVDEVNHH
RGLVNKFQGDASLAVFGAPNRLSHPEDAALATARAIADRLASEMPECQAGIGVAAGQVVAGNVGAHERFEYTVIGEPVNE
AARLCELAKSYPSRLLASSQTLRGASENECARWSLGETVTLRGHDQPIRLASPVQQLQMPAQSADIVGGALGDHQTHTIY
RGAHPTD

Sequences:

>Translated_567_residues
MPSEKATTRHLPGAVETLSPRTGRRPETPAYGSWLLGRVSESPRMRRVRIQGMLTVAILVTNVIGLIVGAMLLTVAFPKP
SVILDAPHWVSFGIVPGYCVLAFILGTYWLTRQTARALRWAIEERTPSHDEARSAFLVPLRVALAVLFLWGAAAALWTII
YGLANRLFIPRFLFSMGVIGVVAATSCYLLTEFALRPMAAQALEVGATPRSLVRGIVGRTMLVWLLCSGVPNVGVALTAI
FDDTFWELSNDQFMITVLILWAPLLIFGFILMWILAWLTATPVRVVREALNRVEQGDLSGDLVVFDGTELGELQRGFNRM
VEGLRERERVRDLFGRHVGREVAAAAERERPKLGGEERHVAVVFVDIVGSTQLVTSRPAAEVVMLLNRFFTVIVDEVNHH
RGLVNKFQGDASLAVFGAPNRLSHPEDAALATARAIADRLASEMPECQAGIGVAAGQVVAGNVGAHERFEYTVIGEPVNE
AARLCELAKSYPSRLLASSQTLRGASENECARWSLGETVTLRGHDQPIRLASPVQQLQMPAQSADIVGGALGDHQTHTIY
RGAHPTD
>Mature_566_residues
PSEKATTRHLPGAVETLSPRTGRRPETPAYGSWLLGRVSESPRMRRVRIQGMLTVAILVTNVIGLIVGAMLLTVAFPKPS
VILDAPHWVSFGIVPGYCVLAFILGTYWLTRQTARALRWAIEERTPSHDEARSAFLVPLRVALAVLFLWGAAAALWTIIY
GLANRLFIPRFLFSMGVIGVVAATSCYLLTEFALRPMAAQALEVGATPRSLVRGIVGRTMLVWLLCSGVPNVGVALTAIF
DDTFWELSNDQFMITVLILWAPLLIFGFILMWILAWLTATPVRVVREALNRVEQGDLSGDLVVFDGTELGELQRGFNRMV
EGLRERERVRDLFGRHVGREVAAAAERERPKLGGEERHVAVVFVDIVGSTQLVTSRPAAEVVMLLNRFFTVIVDEVNHHR
GLVNKFQGDASLAVFGAPNRLSHPEDAALATARAIADRLASEMPECQAGIGVAAGQVVAGNVGAHERFEYTVIGEPVNEA
ARLCELAKSYPSRLLASSQTLRGASENECARWSLGETVTLRGHDQPIRLASPVQQLQMPAQSADIVGGALGDHQTHTIYR
GAHPTD

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HAMP domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00211 Guanylate_cyc; PF00672 HAMP [H]

EC number: 4.6.1.1

Molecular weight: Translated: 61936; Mature: 61804

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: PS50885 HAMP ; PS50125 GUANYLATE_CYCLASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSEKATTRHLPGAVETLSPRTGRRPETPAYGSWLLGRVSESPRMRRVRIQGMLTVAILV
CCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
TNVIGLIVGAMLLTVAFPKPSVILDAPHWVSFGIVPGYCVLAFILGTYWLTRQTARALRW
HHHHHHHHHHHHHHHCCCCCCEEEECCCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
AIEERTPSHDEARSAFLVPLRVALAVLFLWGAAAALWTIIYGLANRLFIPRFLFSMGVIG
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVAATSCYLLTEFALRPMAAQALEVGATPRSLVRGIVGRTMLVWLLCSGVPNVGVALTAI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHH
FDDTFWELSNDQFMITVLILWAPLLIFGFILMWILAWLTATPVRVVREALNRVEQGDLSG
HCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCC
DLVVFDGTELGELQRGFNRMVEGLRERERVRDLFGRHVGREVAAAAERERPKLGGEERHV
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
AVVFVDIVGSTQLVTSRPAAEVVMLLNRFFTVIVDEVNHHRGLVNKFQGDASLAVFGAPN
EEEEEEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
RLSHPEDAALATARAIADRLASEMPECQAGIGVAAGQVVAGNVGAHERFEYTVIGEPVNE
CCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCEEECCCCCCCCEEEEEECCCHHH
AARLCELAKSYPSRLLASSQTLRGASENECARWSLGETVTLRGHDQPIRLASPVQQLQMP
HHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCEECCCCEEEECCCCCCCHHHHHHHHHHCC
AQSADIVGGALGDHQTHTIYRGAHPTD
CHHHHHHCCCCCCCCCCEEECCCCCCC
>Mature Secondary Structure 
PSEKATTRHLPGAVETLSPRTGRRPETPAYGSWLLGRVSESPRMRRVRIQGMLTVAILV
CCCCCCCCCCCCHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
TNVIGLIVGAMLLTVAFPKPSVILDAPHWVSFGIVPGYCVLAFILGTYWLTRQTARALRW
HHHHHHHHHHHHHHHCCCCCCEEEECCCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
AIEERTPSHDEARSAFLVPLRVALAVLFLWGAAAALWTIIYGLANRLFIPRFLFSMGVIG
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVAATSCYLLTEFALRPMAAQALEVGATPRSLVRGIVGRTMLVWLLCSGVPNVGVALTAI
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEHHH
FDDTFWELSNDQFMITVLILWAPLLIFGFILMWILAWLTATPVRVVREALNRVEQGDLSG
HCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCC
DLVVFDGTELGELQRGFNRMVEGLRERERVRDLFGRHVGREVAAAAERERPKLGGEERHV
CEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEE
AVVFVDIVGSTQLVTSRPAAEVVMLLNRFFTVIVDEVNHHRGLVNKFQGDASLAVFGAPN
EEEEEEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
RLSHPEDAALATARAIADRLASEMPECQAGIGVAAGQVVAGNVGAHERFEYTVIGEPVNE
CCCCCCHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCEEECCCCCCCCEEEEEECCCHHH
AARLCELAKSYPSRLLASSQTLRGASENECARWSLGETVTLRGHDQPIRLASPVQQLQMP
HHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCEECCCCEEEECCCCCCCHHHHHHHHHHCC
AQSADIVGGALGDHQTHTIYRGAHPTD
CHHHHHHCCCCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP

Specific reaction: ATP = 3',5'-cyclic AMP + diphosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]