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The map label for this gene is 121637244

Identifier: 121637244

GI number: 121637244

Start: 1496185

End: 1496766

Strand: Reverse

Name: 121637244

Synonym: BCG_1375c

Alternate gene names: NA

Gene position: 1496766-1496185 (Counterclockwise)

Preceding gene: 121637246

Following gene: 121637243

Centisome position: 34.22

GC content: 63.57

Gene sequence:

>582_bases
ATGGCAGTCCACCTGACCCGCATCTATACCCGAACCGGCGATGACGGAACGACGGGATTGAGCGATATGTCCCGTGTCGC
CAAAACCGACGCCCGACTGGTGGCATACGCGGATTGCGACGAGGCCAACGCCGCGATCGGGGCCGCCCTGGCGCTGGGCC
ACCCGGACACTCAAATCACGGATGTGCTGCGGCAGATCCAGAACGACTTGTTCGATGCCGGTGCGGATCTGTCGACTCCG
ATAGTGGAAAACCCGAAGCACCCTCCGCTGCGAATCGCACAGTCCTATATCGATCGGCTCGAAGGGTGGTGCGACGCATA
CAACGCGGGCCTGCCTGCACTAAAATCCTTTGTACTACCTGGTGGTTCACCGCTGTCGGCGCTGTTGCACGTCGCTCGCA
CCGTCGTTCGCCGGGCCGAGCGATCCGCGTGGGCCGCGGTCGACGCTCACCCGGAAGGCGTCAGCGTACTGCCGGCGAAA
TACCTGAACCGGCTGTCGGATCTGCTGTTCATCCTGTCGCGGGTAGCCAATCCCGACGGTGACGTGCTGTGGCGGCCCGG
TGGTGATAGGACGGCGAGCTAG

Upstream 100 bases:

>100_bases
TTGCCCCCAGTCACGACGAAACGCTCGGCCACCCGGTCAGTGTAGTAAAGGGGTTTTGCCTTGTCAGTGAGCCAAGCCAG
TCAGCGAGTACCGTTTGCTC

Downstream 100 bases:

>100_bases
CGGCACCTTCCGCGTGCGAGCAGACGCGAAAGCCCCCAATACCCACGGTTTTTGGGCTCTTCTGACACTTCCGTGGGTGA
GTTTGTGTCCTGAGTAGGCG

Product: hypothetical protein

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase

Number of amino acids: Translated: 193; Mature: 192

Protein sequence:

>193_residues
MAVHLTRIYTRTGDDGTTGLSDMSRVAKTDARLVAYADCDEANAAIGAALALGHPDTQITDVLRQIQNDLFDAGADLSTP
IVENPKHPPLRIAQSYIDRLEGWCDAYNAGLPALKSFVLPGGSPLSALLHVARTVVRRAERSAWAAVDAHPEGVSVLPAK
YLNRLSDLLFILSRVANPDGDVLWRPGGDRTAS

Sequences:

>Translated_193_residues
MAVHLTRIYTRTGDDGTTGLSDMSRVAKTDARLVAYADCDEANAAIGAALALGHPDTQITDVLRQIQNDLFDAGADLSTP
IVENPKHPPLRIAQSYIDRLEGWCDAYNAGLPALKSFVLPGGSPLSALLHVARTVVRRAERSAWAAVDAHPEGVSVLPAK
YLNRLSDLLFILSRVANPDGDVLWRPGGDRTAS
>Mature_192_residues
AVHLTRIYTRTGDDGTTGLSDMSRVAKTDARLVAYADCDEANAAIGAALALGHPDTQITDVLRQIQNDLFDAGADLSTPI
VENPKHPPLRIAQSYIDRLEGWCDAYNAGLPALKSFVLPGGSPLSALLHVARTVVRRAERSAWAAVDAHPEGVSVLPAKY
LNRLSDLLFILSRVANPDGDVLWRPGGDRTAS

Specific function: Unknown

COG id: COG2096

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family

Homologues:

Organism=Homo sapiens, GI16418349, Length=180, Percent_Identity=38.3333333333333, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI115534154, Length=174, Percent_Identity=35.0574712643678, Blast_Score=87, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDUO_MYCBO (P64804)

Other databases:

- EMBL:   BX248338
- RefSeq:   NP_855001.1
- ProteinModelPortal:   P64804
- SMR:   P64804
- EnsemblBacteria:   EBMYCT00000014628
- GeneID:   1090637
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb1347c
- GeneTree:   EBGT00050000014642
- HOGENOM:   HBG645545
- OMA:   MSHLARP
- ProtClustDB:   CLSK871923
- BioCyc:   MBOV233413:MB1347C-MONOMER
- GO:   GO:0005737
- InterPro:   IPR017858
- InterPro:   IPR002779
- InterPro:   IPR016030
- Gene3D:   G3DSA:1.20.1200.10
- PANTHER:   PTHR12213
- ProDom:   PD007457
- TIGRFAMs:   TIGR00636

Pfam domain/function: PF01923 Cob_adeno_trans; SSF89028 AdoCbl_synth_CblAdoTrfase-like

EC number: =2.5.1.17

Molecular weight: Translated: 20695; Mature: 20563

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: BINDING 28-28 BINDING 163-163

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVHLTRIYTRTGDDGTTGLSDMSRVAKTDARLVAYADCDEANAAIGAALALGHPDTQIT
CEEEEEEEEEECCCCCCCCHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHCCCCCHHHH
DVLRQIQNDLFDAGADLSTPIVENPKHPPLRIAQSYIDRLEGWCDAYNAGLPALKSFVLP
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
GGSPLSALLHVARTVVRRAERSAWAAVDAHPEGVSVLPAKYLNRLSDLLFILSRVANPDG
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECHHHHHHHHHHHHHHHHHHCCCCC
DVLWRPGGDRTAS
CEEECCCCCCCCC
>Mature Secondary Structure 
AVHLTRIYTRTGDDGTTGLSDMSRVAKTDARLVAYADCDEANAAIGAALALGHPDTQIT
EEEEEEEEEECCCCCCCCHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHCCCCCHHHH
DVLRQIQNDLFDAGADLSTPIVENPKHPPLRIAQSYIDRLEGWCDAYNAGLPALKSFVLP
HHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
GGSPLSALLHVARTVVRRAERSAWAAVDAHPEGVSVLPAKYLNRLSDLLFILSRVANPDG
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECHHHHHHHHHHHHHHHHHHCCCCC
DVLWRPGGDRTAS
CEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972