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The map label for this gene is oppC [C]

Identifier: 121637210

GI number: 121637210

Start: 1461892

End: 1462767

Strand: Reverse

Name: oppC [C]

Synonym: BCG_1341c

Alternate gene names: 121637210

Gene position: 1462767-1461892 (Counterclockwise)

Preceding gene: 121637211

Following gene: 121637209

Centisome position: 33.44

GC content: 61.64

Gene sequence:

>876_bases
ATGACGGAATTCGCCTCGCGGCGCACCCTAGTGGTGCGCAGGTTCCTACGCAATCGGGCCGCGGTGGCGTCGCTGGCGGC
GCTGCTCCTGCTGTTCGTCAGCGCTTATGCGCTGCCCCCACTATTGCCCTACTCCTACGACGACCTTGATTTCAACGCAT
TGCTGCAGCCGCCGGGCACCAAGCACTGGCTGGGCACTAACGCGCTGGGCCAAGATCTGCTGGCGCAGACGCTGCGTGGC
ATGCAGAAGTCGATGCTGATTGGTGTTTGCGTTGCGGTGATCTCGACTGGTATCGCTGCCACGGTTGGAGCGATCTCGGG
ATATTTCGGCGGCTGGCGGGACCGGACACTGATGTGGGTGGTCGATCTGCTGCTAGTAGTGCCCAGCTTCATCCTGATCG
CCATCGTTACCCCGCGAACCAAGAACTCGGCAAACATCATGTTTCTTGTCTTGTTGTTGGCCGGCTTCGGCTGGATGATC
AGCTCTCGCATGGTGCGCGGGATGACGATGAGCTTGCGAGAACGCGAATTCATCAGGGCCGCACGATATATGGGTGTCTC
CAGCCGCCGGATCATCGTCGGCCATGTGGTGCCCAACGTCGCATCCATCTTGATCATCGACGCCGCCCTCAATGTTGCCG
CCGCCATCCTGGCCGAAACCGGGTTGAGCTTCCTTGGTTTCGGTATTCAACCGCCGGATGTGTCGCTGGGCACCCTGATC
GCCGACGGCACCGCATCCGCGACCGCGTTCCCGTGGGTGTTCTTGTTTCCCGCCAGTATCCTGGTGTTGATTCTGGTGTG
CGCCAACCTGACCGGCGATGGCCTGCGCGACGCGCTGGACCCAGCCAGCAGATCCCTGCGCCGTGGTGTGCGATGA

Upstream 100 bases:

>100_bases
TCGTCGCGGCAATTACCGTGTTCTCCGGCGCGGTCGTGTTGCTGGCCGGTTTGCTCTCGGACGTGATCTACGCGGCTTTG
GACCCGAGGGTACGGGTGTC

Downstream 100 bases:

>100_bases
GCCCCCTGCTCGAGGTGACCGATTTGGCCGTCACCTTCAGGACCGATGGCGATCCGGTGACCGCGGTGCGCGGGATCAGC
TACCGCGTCGAGCCCGGCGA

Product: putative oligopeptide-transport integral membrane protein ABC transporter oppC

Products: ADP; phosphate; oligopeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MTEFASRRTLVVRRFLRNRAAVASLAALLLLFVSAYALPPLLPYSYDDLDFNALLQPPGTKHWLGTNALGQDLLAQTLRG
MQKSMLIGVCVAVISTGIAATVGAISGYFGGWRDRTLMWVVDLLLVVPSFILIAIVTPRTKNSANIMFLVLLLAGFGWMI
SSRMVRGMTMSLREREFIRAARYMGVSSRRIIVGHVVPNVASILIIDAALNVAAAILAETGLSFLGFGIQPPDVSLGTLI
ADGTASATAFPWVFLFPASILVLILVCANLTGDGLRDALDPASRSLRRGVR

Sequences:

>Translated_291_residues
MTEFASRRTLVVRRFLRNRAAVASLAALLLLFVSAYALPPLLPYSYDDLDFNALLQPPGTKHWLGTNALGQDLLAQTLRG
MQKSMLIGVCVAVISTGIAATVGAISGYFGGWRDRTLMWVVDLLLVVPSFILIAIVTPRTKNSANIMFLVLLLAGFGWMI
SSRMVRGMTMSLREREFIRAARYMGVSSRRIIVGHVVPNVASILIIDAALNVAAAILAETGLSFLGFGIQPPDVSLGTLI
ADGTASATAFPWVFLFPASILVLILVCANLTGDGLRDALDPASRSLRRGVR
>Mature_290_residues
TEFASRRTLVVRRFLRNRAAVASLAALLLLFVSAYALPPLLPYSYDDLDFNALLQPPGTKHWLGTNALGQDLLAQTLRGM
QKSMLIGVCVAVISTGIAATVGAISGYFGGWRDRTLMWVVDLLLVVPSFILIAIVTPRTKNSANIMFLVLLLAGFGWMIS
SRMVRGMTMSLREREFIRAARYMGVSSRRIIVGHVVPNVASILIIDAALNVAAAILAETGLSFLGFGIQPPDVSLGTLIA
DGTASATAFPWVFLFPASILVLILVCANLTGDGLRDALDPASRSLRRGVR

Specific function: Part Of The Binding-Protein-Dependent Transport System For Oligopeptides; Probably Responsible For The Translocation Of The Substrate Across The Membrane. [C]

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain

Homologues:

Organism=Escherichia coli, GI1787498, Length=275, Percent_Identity=40.7272727272727, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI1787054, Length=274, Percent_Identity=33.5766423357664, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1787760, Length=245, Percent_Identity=32.2448979591837, Blast_Score=137, Evalue=8e-34,
Organism=Escherichia coli, GI1789889, Length=244, Percent_Identity=29.9180327868852, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1789964, Length=284, Percent_Identity=34.1549295774648, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788505, Length=229, Percent_Identity=33.1877729257642, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1787549, Length=282, Percent_Identity=28.7234042553192, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1282_MYCTU (P66964)

Other databases:

- EMBL:   BX842576
- EMBL:   AE000516
- PIR:   D70729
- RefSeq:   NP_215798.1
- RefSeq:   NP_335766.1
- ProteinModelPortal:   P66964
- EnsemblBacteria:   EBMYCT00000002130
- EnsemblBacteria:   EBMYCT00000072515
- GeneID:   886980
- GeneID:   924753
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT1319
- KEGG:   mtu:Rv1282c
- TIGR:   MT1319
- TubercuList:   Rv1282c
- GeneTree:   EBGT00050000016001
- HOGENOM:   HBG729429
- OMA:   ITSHIVP
- ProtClustDB:   CLSK791078
- InterPro:   IPR000515

Pfam domain/function: PF00528 BPD_transp_1

EC number: NA

Molecular weight: Translated: 31375; Mature: 31243

Theoretical pI: Translated: 11.00; Mature: 11.00

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1585c96c)-; HASH(0x14cb1764)-; HASH(0x126e1134)-; HASH(0x126e1284)-; HASH(0x128d9898)-; HASH(0x12929178)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEFASRRTLVVRRFLRNRAAVASLAALLLLFVSAYALPPLLPYSYDDLDFNALLQPPGT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCC
KHWLGTNALGQDLLAQTLRGMQKSMLIGVCVAVISTGIAATVGAISGYFGGWRDRTLMWV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
VDLLLVVPSFILIAIVTPRTKNSANIMFLVLLLAGFGWMISSRMVRGMTMSLREREFIRA
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARYMGVSSRRIIVGHVVPNVASILIIDAALNVAAAILAETGLSFLGFGIQPPDVSLGTLI
HHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCHHHEE
ADGTASATAFPWVFLFPASILVLILVCANLTGDGLRDALDPASRSLRRGVR
ECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCHHHHHHHCCCH
>Mature Secondary Structure 
TEFASRRTLVVRRFLRNRAAVASLAALLLLFVSAYALPPLLPYSYDDLDFNALLQPPGT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEECCCCC
KHWLGTNALGQDLLAQTLRGMQKSMLIGVCVAVISTGIAATVGAISGYFGGWRDRTLMWV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
VDLLLVVPSFILIAIVTPRTKNSANIMFLVLLLAGFGWMISSRMVRGMTMSLREREFIRA
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARYMGVSSRRIIVGHVVPNVASILIIDAALNVAAAILAETGLSFLGFGIQPPDVSLGTLI
HHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCCCCCCHHHEE
ADGTASATAFPWVFLFPASILVLILVCANLTGDGLRDALDPASRSLRRGVR
ECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCHHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; oligopeptides [Periplasm]; H2O [C]

Specific reaction: ATP + oligopeptides [Periplasm] + H2O = ADP + phosphate + oligopeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036