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The map label for this gene is coaA

Identifier: 121637023

GI number: 121637023

Start: 1250664

End: 1251602

Strand: Reverse

Name: coaA

Synonym: BCG_1152c

Alternate gene names: 121637023

Gene position: 1251602-1250664 (Counterclockwise)

Preceding gene: 121637028

Following gene: 121637014

Centisome position: 28.61

GC content: 62.83

Gene sequence:

>939_bases
ATGTCGCGGCTTAGCGAGCCGAGCCCATATGTCGAGTTCGACCGAAGGCAGTGGCGCGCGCTCCGTATGTCGACTCCGCT
AGCCCTCACCGAAGAAGAACTGGTTGGCCTGCGCGGTCTCGGTGAGCAGATCGACCTGTTGGAGGTCGAAGAGGTCTACC
TACCGCTGGCCCGGCTGATTCACCTGCAAGTCGCCGCCCGCCAACGGCTGTTCGCGGCCACCGCGGAATTTCTCGGCGAG
CCCCAACAAAACCCGGACCGGCCGGTGCCGTTCATCATCGGTGTGGCCGGCAGTGTGGCGGTCGGCAAGTCCACCACCGC
CCGCGTGCTGCAGGCGCTGCTGGCTCGCTGGGATCACCACCCCCGGGTAGATCTGGTGACCACCGACGGCTTTCTCTACC
CCAACGCCGAGCTGCAGCGGCGAAACCTCATGCATCGCAAAGGTTTTCCGGAAAGCTATAACCGCCGGGCACTGATGCGG
TTTGTCACCTCGGTGAAGTCCGGCTCCGACTACGCATGTGCGCCGGTGTATTCGCATTTGCACTACGACATCATCCCGGG
GGCAGAACAAGTGGTCCGCCATCCCGACATCCTGATCCTGGAGGGGCTCAACGTCTTGCAGACCGGCCCCACGCTCATGG
TGTCGGATCTGTTCGATTTTTCGTTGTATGTAGACGCCCGGATCGAGGACATCGAGCAGTGGTACGTATCACGGTTTTTG
GCCATGCGCACCACGGCGTTCGCCGACCCGGAATCACACTTCCACCACTACGCGGCTTTTTCTGACTCGCAGGCCGTCGT
CGCCGCGCGCGAGATCTGGCGGACCATCAACCGGCCCAACCTCGTGGAGAACATTCTGCCGACCCGTCCCCGGGCCACCC
TGGTGCTGCGCAAGGACGCCGATCATTCCATTAACCGGCTGCGGCTGCGCAAGCTGTAA

Upstream 100 bases:

>100_bases
GGGGTACCCCCGGCCCTCGGCACCGACACGGAGTCTGCCAGCACCGCACTTCGCCAGCCCAGCCATCAGGCCCCGCACCC
GTCCCTGCAAGACTGACACC

Downstream 100 bases:

>100_bases
TTGGCGGTCCAATCGCCGGGTGCAGGCGAGTTAGGCCGCCAGCCGGCGCACTCCCGGATATTGCCATCCCTCGAAAACCG
TGGTGTACCCGCCTCGGGCC

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MSRLSEPSPYVEFDRRQWRALRMSTPLALTEEELVGLRGLGEQIDLLEVEEVYLPLARLIHLQVAARQRLFAATAEFLGE
PQQNPDRPVPFIIGVAGSVAVGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELQRRNLMHRKGFPESYNRRALMR
FVTSVKSGSDYACAPVYSHLHYDIIPGAEQVVRHPDILILEGLNVLQTGPTLMVSDLFDFSLYVDARIEDIEQWYVSRFL
AMRTTAFADPESHFHHYAAFSDSQAVVAAREIWRTINRPNLVENILPTRPRATLVLRKDADHSINRLRLRKL

Sequences:

>Translated_312_residues
MSRLSEPSPYVEFDRRQWRALRMSTPLALTEEELVGLRGLGEQIDLLEVEEVYLPLARLIHLQVAARQRLFAATAEFLGE
PQQNPDRPVPFIIGVAGSVAVGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELQRRNLMHRKGFPESYNRRALMR
FVTSVKSGSDYACAPVYSHLHYDIIPGAEQVVRHPDILILEGLNVLQTGPTLMVSDLFDFSLYVDARIEDIEQWYVSRFL
AMRTTAFADPESHFHHYAAFSDSQAVVAAREIWRTINRPNLVENILPTRPRATLVLRKDADHSINRLRLRKL
>Mature_311_residues
SRLSEPSPYVEFDRRQWRALRMSTPLALTEEELVGLRGLGEQIDLLEVEEVYLPLARLIHLQVAARQRLFAATAEFLGEP
QQNPDRPVPFIIGVAGSVAVGKSTTARVLQALLARWDHHPRVDLVTTDGFLYPNAELQRRNLMHRKGFPESYNRRALMRF
VTSVKSGSDYACAPVYSHLHYDIIPGAEQVVRHPDILILEGLNVLQTGPTLMVSDLFDFSLYVDARIEDIEQWYVSRFLA
MRTTAFADPESHFHHYAAFSDSQAVVAAREIWRTINRPNLVENILPTRPRATLVLRKDADHSINRLRLRKL

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family

Homologues:

Organism=Escherichia coli, GI1790409, Length=311, Percent_Identity=52.0900321543408, Blast_Score=334, Evalue=5e-93,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAA_MYCBO (P63811)

Other databases:

- EMBL:   BX248337
- RefSeq:   NP_854778.1
- ProteinModelPortal:   P63811
- SMR:   P63811
- EnsemblBacteria:   EBMYCT00000014487
- GeneID:   1090425
- GenomeReviews:   BX248333_GR
- KEGG:   mbo:Mb1122c
- GeneTree:   EBGT00050000016369
- HOGENOM:   HBG732538
- OMA:   GLNVLQP
- ProtClustDB:   PRK05439
- BioCyc:   MBOV233413:MB1122C-MONOMER
- BRENDA:   2.7.1.33
- GO:   GO:0005737
- HAMAP:   MF_00215
- InterPro:   IPR004566
- InterPro:   IPR006083
- PANTHER:   PTHR10285:SF7
- PIRSF:   PIRSF000545
- TIGRFAMs:   TIGR00554

Pfam domain/function: PF00485 PRK

EC number: =2.7.1.33

Molecular weight: Translated: 35657; Mature: 35526

Theoretical pI: Translated: 7.89; Mature: 7.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLSEPSPYVEFDRRQWRALRMSTPLALTEEELVGLRGLGEQIDLLEVEEVYLPLARLI
CCCCCCCCCCHHHHHHHHHHHHCCCCCEECHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
HLQVAARQRLFAATAEFLGEPQQNPDRPVPFIIGVAGSVAVGKSTTARVLQALLARWDHH
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEECCCHHHHHHHHHHHHCCCC
PRVDLVTTDGFLYPNAELQRRNLMHRKGFPESYNRRALMRFVTSVKSGSDYACAPVYSHL
CCEEEEEECCEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
HYDIIPGAEQVVRHPDILILEGLNVLQTGPTLMVSDLFDFSLYVDARIEDIEQWYVSRFL
EEECCCCHHHHHCCCCEEEECCCHHHHCCCCEEEHHHHCEEEEEECHHHHHHHHHHHHHH
AMRTTAFADPESHFHHYAAFSDSQAVVAAREIWRTINRPNLVENILPTRPRATLVLRKDA
HHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEEECCC
DHSINRLRLRKL
CCCHHHHHHCCC
>Mature Secondary Structure 
SRLSEPSPYVEFDRRQWRALRMSTPLALTEEELVGLRGLGEQIDLLEVEEVYLPLARLI
CCCCCCCCCHHHHHHHHHHHHCCCCCEECHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
HLQVAARQRLFAATAEFLGEPQQNPDRPVPFIIGVAGSVAVGKSTTARVLQALLARWDHH
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCCCEEECCCHHHHHHHHHHHHCCCC
PRVDLVTTDGFLYPNAELQRRNLMHRKGFPESYNRRALMRFVTSVKSGSDYACAPVYSHL
CCEEEEEECCEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
HYDIIPGAEQVVRHPDILILEGLNVLQTGPTLMVSDLFDFSLYVDARIEDIEQWYVSRFL
EEECCCCHHHHHCCCCEEEECCCHHHHCCCCEEEHHHHCEEEEEECHHHHHHHHHHHHHH
AMRTTAFADPESHFHHYAAFSDSQAVVAAREIWRTINRPNLVENILPTRPRATLVLRKDA
HHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCEEEEEECCC
DHSINRLRLRKL
CCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972