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The map label for this gene is 121636818

Identifier: 121636818

GI number: 121636818

Start: 1028239

End: 1029756

Strand: Direct

Name: 121636818

Synonym: BCG_0947

Alternate gene names: NA

Gene position: 1028239-1029756 (Clockwise)

Preceding gene: 121636817

Following gene: 121636819

Centisome position: 23.51

GC content: 67.26

Gene sequence:

>1518_bases
GTGCGCCAACAACAGGAGGCTGACGTCGTTGCCCTGGGTCGAAAGCCAGGGCTGCTATGTGTGCCGGAAAGGTTCCGTGC
AATGGATCTTCCGATGGCAGCCGCCGATGCCTTATTCCTATGGGCCGAGACGCCGACGCGGCCGCTGCATGTCGGCGCGT
TGGCCGTGCTGAGTCAGCCCGACAACGGGACCGGGCGTTACCTGCGCAAGGTGTTCTCCGCCGCGGTGGCCCGTCAGCAG
GTGGCGCCGTGGTGGCGCCGACGCCCGCACCGGTCGCTCACCTCGCTCGGGCAGTGGTCTTGGCGCACCGAGACCGAGGT
GGACCTGGATTACCACGTGCGGCTTAGCGCATTGCCGCCACGGGCCGGTACCGCCGAGCTGTGGGCGTTGGTTTCTGAAC
TACACGCCGGCATGCTGGACCGCTCCCGCCCGCTATGGCAGGTGGACCTGATCGAGGGTCTACCTGGCGGGCGGTGCGCG
GTCTACGTCAAGGTCCACCATGCGCTGGCGGACGGAGTCTCGGTGATGCGGCTTTTACAACGGATCGTCACCGCGGACCC
GCATCAGCGTCAGATGCCCACCTTGTGGGAGGTGCCAGCGCAGGCGTCGGTGGCCAAACACACGGCACCGCGCGGTTCGT
CGAGACCACTGACGTTGGCCAAGGGGGTGCTGGGTCAAGCCAGGGGCGTCCCGGGCATGGTGCGCGTAGTGGCCGATACC
ACGTGGCGGGCAGCGCAATGTCGCAGCGGGCCGCTGACACTGGCCGCACCACACACCCCGCTGAACGAGCCGATCGCCGG
GGCCCGGTCCGTGGCAGGTTGTTCCTTTCCGATCGAGCGGCTGCGACAGGTCGCCGAACACGCCGATGCCACCATCAACG
ATGTCGTGCTGGCCATGTGCGGCGGGGCGTTACGTGCGTACCTGATCAGCCGGGGAGCGTTACCGGGTGCGCCGCTGATA
GCGATGGTGCCGGTTTCGCTGCGCGATACCGCAGTTATCGACGTGTTCGGCCAGGGTCCAGGCAACAAGATCGGTACGTT
GATGTGTTCGCTGGCGACGCACCTGGCCAGTCCGGTCGAACGGCTGTCGGCGATACGGGCAAGTATGCGCGACGGCAAAG
CCGCGATCGCCGGCCGAAGCCGAAACCAGGCGCTGGCTATGAGCGCATTGGGCGCCGCCCCGCTCGCCCTTGCGATGGCC
CTGGGGCGCGTGCCCGCGCCGCTGCGCCCACCAAATGTGACGATCTCCAACGTGCCGGGCCCGCAGGGCGCGCTGTACTG
GAACGGCGCTCGCCTGGACGCGCTCTACCTGCTCTCGGCACCTGTCGATGGCGCGGCGTTGAACATCACCTGTAGCGGCA
CCAATGAGCAGATCACTTTCGGTTTGACGGGCTGCCGTCGTGCCGTCCCCGCGCTGAGCATCCTGACCGACCAGCTCGCC
CACGAACTCGAGCTACTCGTTGGCGTCAGTGAAGCCGGCCCAGGGACCAGACTTCGAAGGATCGCAGGGCGCCGTTAA

Upstream 100 bases:

>100_bases
GGGTCAGGCGGGGTTCGGTACTGATGCGTGAACGTAGCTTAACCGTCGGTGGGAATTGACCGCGCCACCCATAGCAGTCG
AGAGGAACACCCGCAGCAAA

Downstream 100 bases:

>100_bases
ACGGACGCCGCGAGTCATCACCCGGCCGAGCGCGCAGCGGCTTACCTTACGCGCGGCCGCCCATGGTGCCAGAGACCCCA
CCCCGGGCAGGCGGGTCATC

Product: hypothetical protein

Products: NA

Alternate protein names: Putative triacylglycerol synthase Rv0895/MT0919

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MRQQQEADVVALGRKPGLLCVPERFRAMDLPMAAADALFLWAETPTRPLHVGALAVLSQPDNGTGRYLRKVFSAAVARQQ
VAPWWRRRPHRSLTSLGQWSWRTETEVDLDYHVRLSALPPRAGTAELWALVSELHAGMLDRSRPLWQVDLIEGLPGGRCA
VYVKVHHALADGVSVMRLLQRIVTADPHQRQMPTLWEVPAQASVAKHTAPRGSSRPLTLAKGVLGQARGVPGMVRVVADT
TWRAAQCRSGPLTLAAPHTPLNEPIAGARSVAGCSFPIERLRQVAEHADATINDVVLAMCGGALRAYLISRGALPGAPLI
AMVPVSLRDTAVIDVFGQGPGNKIGTLMCSLATHLASPVERLSAIRASMRDGKAAIAGRSRNQALAMSALGAAPLALAMA
LGRVPAPLRPPNVTISNVPGPQGALYWNGARLDALYLLSAPVDGAALNITCSGTNEQITFGLTGCRRAVPALSILTDQLA
HELELLVGVSEAGPGTRLRRIAGRR

Sequences:

>Translated_505_residues
MRQQQEADVVALGRKPGLLCVPERFRAMDLPMAAADALFLWAETPTRPLHVGALAVLSQPDNGTGRYLRKVFSAAVARQQ
VAPWWRRRPHRSLTSLGQWSWRTETEVDLDYHVRLSALPPRAGTAELWALVSELHAGMLDRSRPLWQVDLIEGLPGGRCA
VYVKVHHALADGVSVMRLLQRIVTADPHQRQMPTLWEVPAQASVAKHTAPRGSSRPLTLAKGVLGQARGVPGMVRVVADT
TWRAAQCRSGPLTLAAPHTPLNEPIAGARSVAGCSFPIERLRQVAEHADATINDVVLAMCGGALRAYLISRGALPGAPLI
AMVPVSLRDTAVIDVFGQGPGNKIGTLMCSLATHLASPVERLSAIRASMRDGKAAIAGRSRNQALAMSALGAAPLALAMA
LGRVPAPLRPPNVTISNVPGPQGALYWNGARLDALYLLSAPVDGAALNITCSGTNEQITFGLTGCRRAVPALSILTDQLA
HELELLVGVSEAGPGTRLRRIAGRR
>Mature_505_residues
MRQQQEADVVALGRKPGLLCVPERFRAMDLPMAAADALFLWAETPTRPLHVGALAVLSQPDNGTGRYLRKVFSAAVARQQ
VAPWWRRRPHRSLTSLGQWSWRTETEVDLDYHVRLSALPPRAGTAELWALVSELHAGMLDRSRPLWQVDLIEGLPGGRCA
VYVKVHHALADGVSVMRLLQRIVTADPHQRQMPTLWEVPAQASVAKHTAPRGSSRPLTLAKGVLGQARGVPGMVRVVADT
TWRAAQCRSGPLTLAAPHTPLNEPIAGARSVAGCSFPIERLRQVAEHADATINDVVLAMCGGALRAYLISRGALPGAPLI
AMVPVSLRDTAVIDVFGQGPGNKIGTLMCSLATHLASPVERLSAIRASMRDGKAAIAGRSRNQALAMSALGAAPLALAMA
LGRVPAPLRPPNVTISNVPGPQGALYWNGARLDALYLLSAPVDGAALNITCSGTNEQITFGLTGCRRAVPALSILTDQLA
HELELLVGVSEAGPGTRLRRIAGRR

Specific function: Upon expression in E.coli functions very weakly as a triacylglycerol synthase, making triacylglycerol (TG) from diolein and long-chain fatty acyl-CoA. Has no wax synthase activity

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the long-chain O-acyltransferase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y895_MYCTU (P67204)

Other databases:

- EMBL:   BX842574
- EMBL:   AE000516
- PIR:   D70782
- RefSeq:   NP_215410.1
- RefSeq:   NP_335351.1
- ProteinModelPortal:   P67204
- EnsemblBacteria:   EBMYCT00000000142
- EnsemblBacteria:   EBMYCT00000071388
- GeneID:   885481
- GeneID:   926233
- GenomeReviews:   AE000516_GR
- GenomeReviews:   AL123456_GR
- KEGG:   mtc:MT0919
- KEGG:   mtu:Rv0895
- TIGR:   MT0919
- TubercuList:   Rv0895
- GeneTree:   EBGT00050000015226
- HOGENOM:   HBG696081
- OMA:   GCRRTVP
- ProtClustDB:   CLSK790815
- InterPro:   IPR014292
- InterPro:   IPR004255
- TIGRFAMs:   TIGR02946

Pfam domain/function: PF03007 UPF0089

EC number: =2.3.1.20

Molecular weight: Translated: 53873; Mature: 53873

Theoretical pI: Translated: 10.87; Mature: 10.87

Prosite motif: NA

Important sites: ACT_SITE 167-167

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQQQEADVVALGRKPGLLCVPERFRAMDLPMAAADALFLWAETPTRPLHVGALAVLSQP
CCCCCCCCEEEECCCCCEEECCHHHHHHCCCHHHHCEEEEEECCCCCCEEECEEEEEECC
DNGTGRYLRKVFSAAVARQQVAPWWRRRPHRSLTSLGQWSWRTETEVDLDYHVRLSALPP
CCCHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHCCCCCCCCCEECCEEEEEEEECCC
RAGTAELWALVSELHAGMLDRSRPLWQVDLIEGLPGGRCAVYVKVHHALADGVSVMRLLQ
CCCHHHHHHHHHHHHHHHHHCCCCCEEEEHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHH
RIVTADPHQRQMPTLWEVPAQASVAKHTAPRGSSRPLTLAKGVLGQARGVPGMVRVVADT
HHHCCCCCCCCCCHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECC
TWRAAQCRSGPLTLAAPHTPLNEPIAGARSVAGCSFPIERLRQVAEHADATINDVVLAMC
CHHHHHCCCCCEEEECCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHH
GGALRAYLISRGALPGAPLIAMVPVSLRDTAVIDVFGQGPGNKIGTLMCSLATHLASPVE
HHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
RLSAIRASMRDGKAAIAGRSRNQALAMSALGAAPLALAMALGRVPAPLRPPNVTISNVPG
HHHHHHHHHCCCCEEECCCCCCHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCEEEECCCC
PQGALYWNGARLDALYLLSAPVDGAALNITCSGTNEQITFGLTGCRRAVPALSILTDQLA
CCCEEEECCCCEEEEEEEECCCCCEEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHH
HELELLVGVSEAGPGTRLRRIAGRR
HHHHHHHCCCCCCCCHHHHHHCCCC
>Mature Secondary Structure
MRQQQEADVVALGRKPGLLCVPERFRAMDLPMAAADALFLWAETPTRPLHVGALAVLSQP
CCCCCCCCEEEECCCCCEEECCHHHHHHCCCHHHHCEEEEEECCCCCCEEECEEEEEECC
DNGTGRYLRKVFSAAVARQQVAPWWRRRPHRSLTSLGQWSWRTETEVDLDYHVRLSALPP
CCCHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHCCCCCCCCCEECCEEEEEEEECCC
RAGTAELWALVSELHAGMLDRSRPLWQVDLIEGLPGGRCAVYVKVHHALADGVSVMRLLQ
CCCHHHHHHHHHHHHHHHHHCCCCCEEEEHHCCCCCCCEEEEEEEHHHHHHHHHHHHHHH
RIVTADPHQRQMPTLWEVPAQASVAKHTAPRGSSRPLTLAKGVLGQARGVPGMVRVVADT
HHHCCCCCCCCCCHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECC
TWRAAQCRSGPLTLAAPHTPLNEPIAGARSVAGCSFPIERLRQVAEHADATINDVVLAMC
CHHHHHCCCCCEEEECCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHH
GGALRAYLISRGALPGAPLIAMVPVSLRDTAVIDVFGQGPGNKIGTLMCSLATHLASPVE
HHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH
RLSAIRASMRDGKAAIAGRSRNQALAMSALGAAPLALAMALGRVPAPLRPPNVTISNVPG
HHHHHHHHHCCCCEEECCCCCCHHHHHHHHCHHHHHHHHHHCCCCCCCCCCCEEEECCCC
PQGALYWNGARLDALYLLSAPVDGAALNITCSGTNEQITFGLTGCRRAVPALSILTDQLA
CCCEEEECCCCEEEEEEEECCCCCEEEEEEECCCCCEEEEECHHHHHHHHHHHHHHHHHH
HELELLVGVSEAGPGTRLRRIAGRR
HHHHHHHCCCCCCCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036