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The map label for this gene is narS [H]

Identifier: 121636768

GI number: 121636768

Start: 971696

End: 972973

Strand: Direct

Name: narS [H]

Synonym: BCG_0897

Alternate gene names: 121636768

Gene position: 971696-972973 (Clockwise)

Preceding gene: 121636766

Following gene: 121636770

Centisome position: 22.21

GC content: 62.68

Gene sequence:

>1278_bases
GTGCCCAGCTACGGCAACCTCGGACGTTTGGGCGGTCGCCATGAGTACGGTGTCCTAGTGGCAATGACCAGCTCGGCGGA
ACTGGACCGGGTTCGTTGGGCGCACCAGTTGCGCTCCTACCGAATTGCTTCGGTATTGCGGATCGGTGTCGTGGGGCTCA
TGGTCGCCGCGATGGTCGTTGGAACCAGCCGGTCCGAATGGCCACAGCAAATCGTGTTGATCGGCGTCTACGCGGTCGCT
GCATTGTGGGCTCTGCTGTTAGCGTATTCGGCGTCCCGGCGATTCTTCGCTTTGCGACGCTTTCGCAGTATGGGCCGGTT
GGAGCCATTTGCTTTCACCGCCGTCGACGTTTTGATATTGACGGGCTTTCAGCTGCTGTCCACCGACGGGATCTATCCGC
TGCTGATCATGATCCTGCTGCCGGTCCTGGTGGGCCTTGACGTGTCGACGCGACGGGCGGCGGTGGTGCTGGCCTGTACG
CTAGTCGGATTCGCAGTCGCGGTGCTGGGAGACCCCGTGATGCTGCGCGCGATTGGATGGCCCGAGACAATATTTCGGTT
CGCGCTCTATGCGTTCCTGTGCGCCACGGCCTTGATGGTGGTTCGCATCGAGGAGCGGCATACCCGTTCGGTTGCCGGCC
TGAGTGCGTTGCGGGAGGAACTGCTTGCCCAGACGATGACGGCCTCGGAGGTGCTGCAGCGGCGGATTGCGGAAGCCATT
CACGATGGACCGCTGCAAGACGTGCTGGCCGCGCGTCAGGAGCTCATCGAGTTGGATGCCGTAACCCCCGGCGACGAGCG
CGTCGGACGCGCGTTGGCCGGACTGCAGAGCGCGTCGGAGCGGCTGCGGCAGGCCACCTTCGAGCTGCATCCGGCAGTGC
TTGAGCAAGTTGGGTTGGGGCCGGCGGTAAAACAGTTGGCGGCCTCTACCGCTCAGCGTTCGGGTATCAAGATCTCCACC
GATATTGATTACCCAATACGTAGTGGGATCGACCCCATCGTTTTCGGTGTGGTTCGCGAACTGCTGTCCAACGTCGTGCG
GCATTCCGGAGCTACCACCGCCTCGGTCAGGCTCGGAATCACCGACGAAAAATGCGTTTTGGATGTGGCCGACGATGGCG
TGGGGGTCACCGGTGACACTATGGCGCGCCGCCTGGGTGAGGGACACATCGGTCTGGCTTCGCATCGGGCTCGGGTGGAT
GCCGCCGGCGGAGTTTTGGTTTTCCTGGCCACCCCCAGGGGGACCCATGTCTGCGTGGAACTACCACTGAAACGGTGA

Upstream 100 bases:

>100_bases
GGCTGCGGATTGCTCATGGCGCGCCGACCATGGCGATGAGTTTAGCTGCTCGTCGGCAACCAGCCGCTGGCAGTCGCTGG
ACATTGATTTGCACTCCGAC

Downstream 100 bases:

>100_bases
ATGGCCGTTGTTGCCGGTCAACCGATGTGCCGGTGGCAGCGACGTGACCCCCGCGCAGGTCGAAAGCCTTGCTGGATCGA
TGGTTCCGCCGGTGCCCGCC

Product: putative two component sensor kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MPSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVVGTSRSEWPQQIVLIGVYAVA
ALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLILTGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACT
LVGFAVAVLGDPVMLRAIGWPETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALREELLAQTMTASEVLQRRIAEAI
HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLGPAVKQLAASTAQRSGIKIST
DIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGITDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVD
AAGGVLVFLATPRGTHVCVELPLKR

Sequences:

>Translated_425_residues
MPSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVVGTSRSEWPQQIVLIGVYAVA
ALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLILTGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACT
LVGFAVAVLGDPVMLRAIGWPETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALREELLAQTMTASEVLQRRIAEAI
HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLGPAVKQLAASTAQRSGIKIST
DIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGITDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVD
AAGGVLVFLATPRGTHVCVELPLKR
>Mature_424_residues
PSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVVGTSRSEWPQQIVLIGVYAVAA
LWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLILTGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTL
VGFAVAVLGDPVMLRAIGWPETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALREELLAQTMTASEVLQRRIAEAIH
DGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLGPAVKQLAASTAQRSGIKISTD
IDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGITDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDA
AGGVLVFLATPRGTHVCVELPLKR

Specific function: Probable member of the two-component regulatory system NarS/NarL. May activate NarL by phosphorylation [H]

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR005467 [H]

Pfam domain/function: PF02518 HATPase_c [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 45842; Mature: 45711

Theoretical pI: Translated: 9.17; Mature: 9.17

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV
CCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLIL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW
HCHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHEEECCC
PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALREELLAQTMTASEVLQRRIAEAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCC
PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI
HHHHHHHHHHHHHCCCEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVE
CCCCEEEEECCCCCCCCHHHHHHHHCCCCCCHHHHHHHEECCCCEEEEEECCCCCEEEEE
LPLKR
ECCCC
>Mature Secondary Structure 
PSYGNLGRLGGRHEYGVLVAMTSSAELDRVRWAHQLRSYRIASVLRIGVVGLMVAAMVV
CCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GTSRSEWPQQIVLIGVYAVAALWALLLAYSASRRFFALRRFRSMGRLEPFAFTAVDVLIL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
TGFQLLSTDGIYPLLIMILLPVLVGLDVSTRRAAVVLACTLVGFAVAVLGDPVMLRAIGW
HCHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHEEECCC
PETIFRFALYAFLCATALMVVRIEERHTRSVAGLSALREELLAQTMTASEVLQRRIAEAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HDGPLQDVLAARQELIELDAVTPGDERVGRALAGLQSASERLRQATFELHPAVLEQVGLG
CCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHCCC
PAVKQLAASTAQRSGIKISTDIDYPIRSGIDPIVFGVVRELLSNVVRHSGATTASVRLGI
HHHHHHHHHHHHHCCCEEECCCCCHHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
TDEKCVLDVADDGVGVTGDTMARRLGEGHIGLASHRARVDAAGGVLVFLATPRGTHVCVE
CCCCEEEEECCCCCCCCHHHHHHHHCCCCCCHHHHHHHEECCCCEEEEEECCCCCEEEEE
LPLKR
ECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]