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The map label for this gene is fadE9 [H]

Identifier: 121636675

GI number: 121636675

Start: 875025

End: 876197

Strand: Reverse

Name: fadE9 [H]

Synonym: BCG_0803c

Alternate gene names: 121636675

Gene position: 876197-875025 (Counterclockwise)

Preceding gene: 121636676

Following gene: 121636674

Centisome position: 20.03

GC content: 67.01

Gene sequence:

>1173_bases
ATGTTTGTCCTTAACGACGACGAACGGGTGATCGTCGAGACGGCGGCCGCCTTCGCCGGCAAACGCCTGGCTCCGCACGC
CCTGGAATGGGATGCCGCCAAACACTTTCCGGTGGACGTGTTGCGGGAAGCGGCCGAACTCGGCATGGCCGCGATCTATT
GCCGCGACGACGTCGGCGGCAGTGGGCTGCGCCGGCTCGACGGCGCGCGCATCTTCGAGCAGTTGGCGATCGCCGACCCG
GTGACCGCCGCGTTTTTGTCCATCCACAACATGTGCGCGTGGATGATTGACAGCTTCGGCACCGACGAGCAACGCAAGGA
CTGGATTCCGCGACTGGCCACCATGGGCGTCATCGCCAGCTACTGCCTGACCGAACCGGGCGCCGGATCCGATGCCGGCG
CACTGAGCACCCGCGCCGTCAGGCACGGCTCAGGAAAAGGCGGCGACTACGTGCTCGATGGCGTCAAACAATTCATTTCC
GGGGCCGCAGCATCGGACGTGTATGTGGTGATGGCGCGCACGGGCGCCGAGGGTCCGCGCGGCGTGTCGGCGTTCGTCGT
CGAAAAGGGCACACCGGGGCTGAGTTTCGGCGCGCCCGAAGCGAAGATGGGTTGGCATGCCCAACCCACCGCGCAGGTGG
TGCTGGACGGGGTGCGGGTACCCGCCGAGGCCATGCTGGGCGGCGCCGACGGCGAAGGCGCCGGCTTCGGTATCGCGATG
AGCGGCCTCAACGGCGGCCGGCTCAATATCGCAGCATGCTCGCTGGGTGGCGCGCAGGCCGCCTTTGACAAAGCGGGCGC
CTACGTTCGCGACCGACAGGCCTTCGGCGGATCGCTGCTCGACGAGCCCACCGTGCGGTTTACCCTGGCCGACATGGCTA
CCGGGCTGCAGACGTCGCGAATGTTGTTGTGGCGGGCCGCAAGTGCGCTCGATGACGACGACGCCGACAAGGTCGAGCTG
TGTGCGATGGCCAAGCGCTACGTCACCGACACCTGCTTTGAGGTCGCCGACCAGGCCCTGCAGCTGCACGGCGGCTATGG
CTATCTGCGCGAGTATGGTCTGGAGAAGATCGTCCGCGACCTGCGGGTGCATCGCATCCTGGAAGGGACCAACGAGATCA
TGCGGCTGGTCATCGGTCGGGCCGAGGCCGCGCGGTTCCGCGCCACCGTTTAG

Upstream 100 bases:

>100_bases
AATCCAGTTCTACACCAAGGTCAAGACCGTCACGTCGCGATGGCCGTCAGGCATCAAGGACGGTGCCGAATTCGTCATCC
CCACAATGAGTTAGCGTGTC

Downstream 100 bases:

>100_bases
AGAGGCTCAGATGACGACCATCGCCTTCCTAGGTTTGGGCAACATGGGTGCGCCGATGTCGGCGAATCTGGTTGGTGCGG
GCCACGTCGTGCGTGGATTC

Product: putative acyl-CoA dehydrogenase fadE9

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MFVLNDDERVIVETAAAFAGKRLAPHALEWDAAKHFPVDVLREAAELGMAAIYCRDDVGGSGLRRLDGARIFEQLAIADP
VTAAFLSIHNMCAWMIDSFGTDEQRKDWIPRLATMGVIASYCLTEPGAGSDAGALSTRAVRHGSGKGGDYVLDGVKQFIS
GAAASDVYVVMARTGAEGPRGVSAFVVEKGTPGLSFGAPEAKMGWHAQPTAQVVLDGVRVPAEAMLGGADGEGAGFGIAM
SGLNGGRLNIAACSLGGAQAAFDKAGAYVRDRQAFGGSLLDEPTVRFTLADMATGLQTSRMLLWRAASALDDDDADKVEL
CAMAKRYVTDTCFEVADQALQLHGGYGYLREYGLEKIVRDLRVHRILEGTNEIMRLVIGRAEAARFRATV

Sequences:

>Translated_390_residues
MFVLNDDERVIVETAAAFAGKRLAPHALEWDAAKHFPVDVLREAAELGMAAIYCRDDVGGSGLRRLDGARIFEQLAIADP
VTAAFLSIHNMCAWMIDSFGTDEQRKDWIPRLATMGVIASYCLTEPGAGSDAGALSTRAVRHGSGKGGDYVLDGVKQFIS
GAAASDVYVVMARTGAEGPRGVSAFVVEKGTPGLSFGAPEAKMGWHAQPTAQVVLDGVRVPAEAMLGGADGEGAGFGIAM
SGLNGGRLNIAACSLGGAQAAFDKAGAYVRDRQAFGGSLLDEPTVRFTLADMATGLQTSRMLLWRAASALDDDDADKVEL
CAMAKRYVTDTCFEVADQALQLHGGYGYLREYGLEKIVRDLRVHRILEGTNEIMRLVIGRAEAARFRATV
>Mature_390_residues
MFVLNDDERVIVETAAAFAGKRLAPHALEWDAAKHFPVDVLREAAELGMAAIYCRDDVGGSGLRRLDGARIFEQLAIADP
VTAAFLSIHNMCAWMIDSFGTDEQRKDWIPRLATMGVIASYCLTEPGAGSDAGALSTRAVRHGSGKGGDYVLDGVKQFIS
GAAASDVYVVMARTGAEGPRGVSAFVVEKGTPGLSFGAPEAKMGWHAQPTAQVVLDGVRVPAEAMLGGADGEGAGFGIAM
SGLNGGRLNIAACSLGGAQAAFDKAGAYVRDRQAFGGSLLDEPTVRFTLADMATGLQTSRMLLWRAASALDDDDADKVEL
CAMAKRYVTDTCFEVADQALQLHGGYGYLREYGLEKIVRDLRVHRILEGTNEIMRLVIGRAEAARFRATV

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7656849, Length=378, Percent_Identity=52.6455026455027, Blast_Score=411, Evalue=1e-115,
Organism=Homo sapiens, GI4557233, Length=377, Percent_Identity=37.1352785145889, Blast_Score=225, Evalue=6e-59,
Organism=Homo sapiens, GI4557231, Length=390, Percent_Identity=32.0512820512821, Blast_Score=219, Evalue=3e-57,
Organism=Homo sapiens, GI187960098, Length=390, Percent_Identity=32.0512820512821, Blast_Score=219, Evalue=4e-57,
Organism=Homo sapiens, GI4501859, Length=386, Percent_Identity=33.160621761658, Blast_Score=208, Evalue=8e-54,
Organism=Homo sapiens, GI4557235, Length=360, Percent_Identity=34.1666666666667, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI76496475, Length=360, Percent_Identity=34.1666666666667, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI4501857, Length=382, Percent_Identity=32.9842931937173, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI226958412, Length=390, Percent_Identity=31.025641025641, Blast_Score=187, Evalue=2e-47,
Organism=Homo sapiens, GI226958414, Length=350, Percent_Identity=31.1428571428571, Blast_Score=171, Evalue=1e-42,
Organism=Homo sapiens, GI21361497, Length=354, Percent_Identity=29.3785310734463, Blast_Score=167, Evalue=1e-41,
Organism=Homo sapiens, GI4503943, Length=383, Percent_Identity=30.8093994778068, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI7669494, Length=354, Percent_Identity=30.7909604519774, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI48976061, Length=296, Percent_Identity=27.3648648648649, Blast_Score=93, Evalue=4e-19,
Organism=Homo sapiens, GI211971008, Length=296, Percent_Identity=27.3648648648649, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI38505218, Length=306, Percent_Identity=26.797385620915, Blast_Score=90, Evalue=4e-18,
Organism=Escherichia coli, GI87081958, Length=356, Percent_Identity=32.0224719101124, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1786223, Length=389, Percent_Identity=27.2493573264781, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI87082384, Length=275, Percent_Identity=29.4545454545455, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI87081702, Length=340, Percent_Identity=24.7058823529412, Blast_Score=69, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17533517, Length=379, Percent_Identity=48.5488126649077, Blast_Score=374, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI17534899, Length=389, Percent_Identity=35.2185089974293, Blast_Score=231, Evalue=5e-61,
Organism=Caenorhabditis elegans, GI17569725, Length=385, Percent_Identity=33.7662337662338, Blast_Score=221, Evalue=6e-58,
Organism=Caenorhabditis elegans, GI17506239, Length=380, Percent_Identity=31.8421052631579, Blast_Score=194, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI71985184, Length=357, Percent_Identity=33.6134453781513, Blast_Score=193, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI17538396, Length=389, Percent_Identity=33.4190231362468, Blast_Score=191, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI17508101, Length=379, Percent_Identity=31.3984168865435, Blast_Score=191, Evalue=8e-49,
Organism=Caenorhabditis elegans, GI17570075, Length=388, Percent_Identity=29.8969072164948, Blast_Score=182, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17534353, Length=380, Percent_Identity=30.5263157894737, Blast_Score=160, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI71990804, Length=292, Percent_Identity=32.8767123287671, Blast_Score=154, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17551932, Length=378, Percent_Identity=28.5714285714286, Blast_Score=149, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI17505929, Length=389, Percent_Identity=28.2776349614396, Blast_Score=147, Evalue=6e-36,
Organism=Caenorhabditis elegans, GI32563615, Length=232, Percent_Identity=36.6379310344828, Blast_Score=145, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI71982178, Length=280, Percent_Identity=31.4285714285714, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI71985192, Length=287, Percent_Identity=32.404181184669, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17531909, Length=245, Percent_Identity=26.9387755102041, Blast_Score=85, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17562446, Length=346, Percent_Identity=26.878612716763, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI86563381, Length=313, Percent_Identity=29.7124600638978, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI86563383, Length=313, Percent_Identity=29.7124600638978, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24646207, Length=379, Percent_Identity=36.9393139841689, Blast_Score=219, Evalue=4e-57,
Organism=Drosophila melanogaster, GI24660351, Length=393, Percent_Identity=34.3511450381679, Blast_Score=218, Evalue=6e-57,
Organism=Drosophila melanogaster, GI24666513, Length=379, Percent_Identity=34.3007915567282, Blast_Score=216, Evalue=2e-56,
Organism=Drosophila melanogaster, GI21356377, Length=377, Percent_Identity=35.0132625994695, Blast_Score=214, Evalue=7e-56,
Organism=Drosophila melanogaster, GI281363737, Length=340, Percent_Identity=34.1176470588235, Blast_Score=196, Evalue=2e-50,
Organism=Drosophila melanogaster, GI21355753, Length=393, Percent_Identity=32.3155216284987, Blast_Score=179, Evalue=3e-45,
Organism=Drosophila melanogaster, GI19920834, Length=385, Percent_Identity=28.5714285714286, Blast_Score=133, Evalue=3e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 41410; Mature: 41410

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVLNDDERVIVETAAAFAGKRLAPHALEWDAAKHFPVDVLREAAELGMAAIYCRDDVGG
CEEECCCCEEEHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEEECCCCC
SGLRRLDGARIFEQLAIADPVTAAFLSIHNMCAWMIDSFGTDEQRKDWIPRLATMGVIAS
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
YCLTEPGAGSDAGALSTRAVRHGSGKGGDYVLDGVKQFISGAAASDVYVVMARTGAEGPR
HHHCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCC
GVSAFVVEKGTPGLSFGAPEAKMGWHAQPTAQVVLDGVRVPAEAMLGGADGEGAGFGIAM
CCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHCCCCCCCCCCCEEEE
SGLNGGRLNIAACSLGGAQAAFDKAGAYVRDRQAFGGSLLDEPTVRFTLADMATGLQTSR
ECCCCCEEEEEEECCCCHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEHHHHHCCHHHHH
MLLWRAASALDDDDADKVELCAMAKRYVTDTCFEVADQALQLHGGYGYLREYGLEKIVRD
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LRVHRILEGTNEIMRLVIGRAEAARFRATV
HHHHHHHHHHHHHHHHHHCCHHHHHHCCCC
>Mature Secondary Structure
MFVLNDDERVIVETAAAFAGKRLAPHALEWDAAKHFPVDVLREAAELGMAAIYCRDDVGG
CEEECCCCEEEHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEEECCCCC
SGLRRLDGARIFEQLAIADPVTAAFLSIHNMCAWMIDSFGTDEQRKDWIPRLATMGVIAS
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
YCLTEPGAGSDAGALSTRAVRHGSGKGGDYVLDGVKQFISGAAASDVYVVMARTGAEGPR
HHHCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCC
GVSAFVVEKGTPGLSFGAPEAKMGWHAQPTAQVVLDGVRVPAEAMLGGADGEGAGFGIAM
CCEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCHHHHCCCCCCCCCCCEEEE
SGLNGGRLNIAACSLGGAQAAFDKAGAYVRDRQAFGGSLLDEPTVRFTLADMATGLQTSR
ECCCCCEEEEEEECCCCHHHHHHHCCCHHHHHHHHCCCCCCCCCEEEEHHHHHCCHHHHH
MLLWRAASALDDDDADKVELCAMAKRYVTDTCFEVADQALQLHGGYGYLREYGLEKIVRD
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
LRVHRILEGTNEIMRLVIGRAEAARFRATV
HHHHHHHHHHHHHHHHHHCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]