Click here to switch to the map view.

The map label for this gene is ygiY [C]

Identifier: 121636519

GI number: 121636519

Start: 729409

End: 729879

Strand: Reverse

Name: ygiY [C]

Synonym: BCG_0647c

Alternate gene names: 121636519

Gene position: 729879-729409 (Counterclockwise)

Preceding gene: 121636520

Following gene: 121636518

Centisome position: 16.68

GC content: 69.43

Gene sequence:

>471_bases
ATGGCGCTCGTTCTGGCAGCAGCCGGTGCCGTCACCGTCGTCCAGTTCCGCGACGCCGCTCACGAAGCCGACCCCGATGG
CGCGCTGCGCGGGCTCACCGACGACATCACCGCCGATCTGGTCCGGGAATTGGTGACCATCCTGCCGATCGTGCTCGTCA
TCGCCGCGGTGGCCGCCTACCTGCTCAGCCGCGCCGCGCTGCGGCCCGTCGACCGGATCCGCGCGGCGGCGCAAACACTG
ACCACCACGCCGCACCCCGACACCGACGCGCCGCTGCCGGTACCTCCCACCGACGACGAGATCGCTTGGCTAGCAACGAC
TCTCAACACCATGCTCACCCGACTGCAACGGGCCCTCGCCCACGAACAACAGTTCGTCGCCGACGCCAGCCACGAATTAC
GCACCCCGTTGGCACTGCTGACCACCGAACTCGAACTGCGCTGCGCCGGCCCAGACCCGCCGACCAGCTGA

Upstream 100 bases:

>100_bases
CGCGGTGCCGGATACCGGCTGCGCAAGGACGGAGGACGGCATGCGCTCCCCCGCTGAGTGGCCCATCCGATGGCGACTCA
CCCTCGTCTTCAGCGCCGCC

Downstream 100 bases:

>100_bases
GCGCCGCCCTGCGCTCCGCGCTCGAAGAAACCCGCCGGCTCAGCGGACTGGCCGACCAACTGCTCACCCTGGCCCGCGCC
GACCGCCCCGAATCCCACCC

Product: putative two component sensor kinase (first part)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MALVLAAAGAVTVVQFRDAAHEADPDGALRGLTDDITADLVRELVTILPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTL
TTTPHPDTDAPLPVPPTDDEIAWLATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCAGPDPPTS

Sequences:

>Translated_156_residues
MALVLAAAGAVTVVQFRDAAHEADPDGALRGLTDDITADLVRELVTILPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTL
TTTPHPDTDAPLPVPPTDDEIAWLATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCAGPDPPTS
>Mature_155_residues
ALVLAAAGAVTVVQFRDAAHEADPDGALRGLTDDITADLVRELVTILPIVLVIAAVAAYLLSRAALRPVDRIRAAAQTLT
TTPHPDTDAPLPVPPTDDEIAWLATTLNTMLTRLQRALAHEQQFVADASHELRTPLALLTTELELRCAGPDPPTS

Specific function: Member of the three-protein two-component system HK1/HK2/tcrA. HK2 transfers its phosphoryl group to tcrA

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HK2_MYCTU (O07777)

Other databases:

- EMBL:   BX842574
- PIR:   D70909
- RefSeq:   NP_215115.1
- ProteinModelPortal:   O07777
- SMR:   O07777
- MINT:   MINT-4653432
- EnsemblBacteria:   EBMYCT00000003619
- GeneID:   887868
- GenomeReviews:   AL123456_GR
- KEGG:   mtu:Rv0601c
- TubercuList:   Rv0601c
- GeneTree:   EBGT00050000014829
- HOGENOM:   HBG128115
- ProtClustDB:   CLSK2748598
- InterPro:   IPR003660
- InterPro:   IPR003661
- InterPro:   IPR009082
- SMART:   SM00304

Pfam domain/function: PF00672 HAMP; PF00512 HisKA; SSF47384 His_kin_homodim

EC number: =2.7.13.3

Molecular weight: Translated: 16595; Mature: 16464

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS50885 HAMP; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1405b63c)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALVLAAAGAVTVVQFRDAAHEADPDGALRGLTDDITADLVRELVTILPIVLVIAAVAAY
CEEEEECCCHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTLNTMLTRLQRALA
HHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
HEQQFVADASHELRTPLALLTTELELRCAGPDPPTS
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCH
>Mature Secondary Structure 
ALVLAAAGAVTVVQFRDAAHEADPDGALRGLTDDITADLVRELVTILPIVLVIAAVAAY
EEEEECCCHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLSRAALRPVDRIRAAAQTLTTTPHPDTDAPLPVPPTDDEIAWLATTLNTMLTRLQRALA
HHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
HEQQFVADASHELRTPLALLTTELELRCAGPDPPTS
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230