BacMap

Definition	Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome.
Accession	NC_008769
Length	4,374,522

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The map label for this gene is hflB [C]

Identifier: 121636349

GI number: 121636349

Start: 553162

End: 555348

Strand: Reverse

Name: hflB [C]

Synonym: BCG_0474c

Alternate gene names: 121636349

Gene position: 555348-553162 (Counterclockwise)

Preceding gene: 121636350

Following gene: 121636343

Centisome position: 12.7

GC content: 69.0

Gene sequence:

>2187_bases
GTGACCCACCCGGACCCGGCCCGCCAACTCACCCTTACCGCCCGGCTGAACACCTCGGCCGTCGACTCACGCCGCGGCGT
CGTTCGGTTGCACCCCAATGCCATTGCTGCCCTTGGCATCCGCGAGTGGGACGCGGTGTCGCTGACCGGCTCTCGGACAA
CCGCCGCGGTCGCCGGCCTGGCCGCGGCAGACACCGCGGTCGGGACGGTGCTGCTCGATGACGTCACACTGTCCAATGCG
GGCCTTCGCGAAGGCACCGAGGTGATCGTCAGCCCGGTCACCGTCTACGGAGCGCGATCGGTGACGCTGAGCGGTTCAAC
GCTGGCCACCCAGTCGGTGCCGCCGGTCACGCTGCGGCAGGCCCTACTCGGCAAGGTGATGACCGTCGGTGACGCGGTCT
CGCTGCTGCCCCGCGATCTAGGCCCCGGCACATCCACGTCGGCTGCCAGCCGCGCATTGGCAGCTGCGGTCGGGATCAGT
TGGACCTCGGAGCTGCTGACCGTTACCGGCGTCGACCCCGACGGGCCGGTCAGCGTGCAGCCCAACTCGCTGGTCACCTG
GGGCGCTGGGGTCCCGGCCGCAATGGGTACGTCCACGGCCGGGCAAGTGAGCATCTCGAGTCCGGAGATCCAGATCGAAG
AGCTCAAGGGCGCCCAGCCGCAGGCTGCCAAGCTCACCGAATGGCTCAAGCTTGCCCTCGATGAGCCGCACCTACTACAG
ACCTTGGGCGCCGGCACCAATTTGGGTGTGCTGGTGTCGGGTCCGGCCGGGGTGGGCAAGGCGACGCTGGTGCGCGCGGT
GTGCGACGGCCGAAGGTTGGTGACACTGGATGGTCCGGAGATTGGAGCTCTGGCCGCCGGAGACCGGGTCAAAGCCGTGG
CCTCGGCAGTGCAGGCGGTTCGCCATGAGGGCGGTGTGTTGCTGATCACCGATGCCGACGCCCTGCTGCCAGCCGCCGCC
GAGCCGGTAGCCTCGCTGATCCTGTCCGAGCTGCGTACCGCGGTGGCCACCGCCGGTGTGGTATTGATCGCCACCTCAGC
ACGGCCCGATCAACTCGATGCCCGGCTGCGTTCCCCCGAGTTGTGCGACCGGGAGCTTGGCCTGCCGCTGCCCGACGCGG
CCACCCGCAAATCGCTGCTGGAGGCGCTGCTGAATCCGGTTCCTACCGGAGACCTCAACCTCGACGAAATCGCCTCCCGC
ACACCGGGTTTCGTCGTGGCCGACCTGGCTGCGCTGGTTCGCGAGGCGGCGCTGCGGGCAGCGTCTCGAGCCAGTGCCGA
CGGCCGACCACCGATGCTGCACCAAGACGACCTCCTCGGTGCGTTGACCGTCATCCGGCCGCTGTCCCGCTCGGCCAGCG
ACGAAGTCACCGTGGGTGACGTGACGCTCGACGATGTCGGTGACATGGCCGCGGCCAAACAAGCACTGACCGAGGCGGTG
CTGTGGCCGCTGCAGCACCCCGACACCTTCGCTCGGCTAGGTGTCGAACCGCCGCGCGGGGTGTTGCTGTACGGCCCGCC
CGGCTGCGGCAAGACCTTTGTGGTTCGTGCCCTGGCCAGCACCGGACAGTTGAGCGTGCATGCCGTCAAAGGGTCGGAGC
TGATGGACAAGTGGGTGGGCTCCTCGGAGAAGGCAGTCCGCGAGCTATTCCGGCGGGCCCGCGACTCCGCGCCGTCACTG
GTGTTCCTCGACGAGCTGGACGCTCTGGCGCCACGGCGCGGTCAGAGCTTCGACTCGGGCGTCTCCGACCGGGTGGTGGC
CGCGCTGCTGACTGAGCTCGACGGTATTGACCCGCTGCGGGATGTCGTCATGCTAGGCGCGACCAACCGGCCCGATCTGA
TAGACCCGGCGCTGCTGCGCCCGGGGCGGCTAGAACGGCTGGTGTTCGTTGAACCGCCCGACGCTGCCGCTCGCCGCGAA
ATCCTGCGCACCGCTGGCAAGTCGATCCCGCTGAGCTCCGACGTCGACCTGGACGAGGTGGCAGCCGGACTCGACGGTTA
TAGTGCCGCCGACTGTGTGGCGCTGCTGCGCGAAGCCGCGCTTACCGCGATGCGGCGTTCCATCGATGCCGCCAACGTCA
CCGCCGCCGACCTGGCGACCGCGCGAGAAACCGTGCGCGCGTCGCTGGATCCGCTGCAGGTGGCGTCGCTGCGTAAGTTC
GGCACCAAGGGTGACCTTCGGTCCTAG

Upstream 100 bases:

>100_bases
AGCCCAAGCAACGGCGCGCGGTGCGGCGCGCGAGCCGCCGGGCGCATCCCTACCGGCCGTCGATGGCGCGGCTGGGCCTG
CGCAAGCCGGGTCGACGGCT

Downstream 100 bases:

>100_bases
CGACCACTGATGAAGTCGAGCAATTGCGGGTACTGGTCGGCAATGGTGCGAAGGCGTTGACCATTGTCGAGCCGGTTCCG
CACCCGGATGCGCTTGCCGG

Product: putative atpase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 728; Mature: 727

Protein sequence:

>728_residues
MTHPDPARQLTLTARLNTSAVDSRRGVVRLHPNAIAALGIREWDAVSLTGSRTTAAVAGLAAADTAVGTVLLDDVTLSNA
GLREGTEVIVSPVTVYGARSVTLSGSTLATQSVPPVTLRQALLGKVMTVGDAVSLLPRDLGPGTSTSAASRALAAAVGIS
WTSELLTVTGVDPDGPVSVQPNSLVTWGAGVPAAMGTSTAGQVSISSPEIQIEELKGAQPQAAKLTEWLKLALDEPHLLQ
TLGAGTNLGVLVSGPAGVGKATLVRAVCDGRRLVTLDGPEIGALAAGDRVKAVASAVQAVRHEGGVLLITDADALLPAAA
EPVASLILSELRTAVATAGVVLIATSARPDQLDARLRSPELCDRELGLPLPDAATRKSLLEALLNPVPTGDLNLDEIASR
TPGFVVADLAALVREAALRAASRASADGRPPMLHQDDLLGALTVIRPLSRSASDEVTVGDVTLDDVGDMAAAKQALTEAV
LWPLQHPDTFARLGVEPPRGVLLYGPPGCGKTFVVRALASTGQLSVHAVKGSELMDKWVGSSEKAVRELFRRARDSAPSL
VFLDELDALAPRRGQSFDSGVSDRVVAALLTELDGIDPLRDVVMLGATNRPDLIDPALLRPGRLERLVFVEPPDAAARRE
ILRTAGKSIPLSSDVDLDEVAAGLDGYSAADCVALLREAALTAMRRSIDAANVTAADLATARETVRASLDPLQVASLRKF
GTKGDLRS

Sequences:

>Translated_728_residues
MTHPDPARQLTLTARLNTSAVDSRRGVVRLHPNAIAALGIREWDAVSLTGSRTTAAVAGLAAADTAVGTVLLDDVTLSNA
GLREGTEVIVSPVTVYGARSVTLSGSTLATQSVPPVTLRQALLGKVMTVGDAVSLLPRDLGPGTSTSAASRALAAAVGIS
WTSELLTVTGVDPDGPVSVQPNSLVTWGAGVPAAMGTSTAGQVSISSPEIQIEELKGAQPQAAKLTEWLKLALDEPHLLQ
TLGAGTNLGVLVSGPAGVGKATLVRAVCDGRRLVTLDGPEIGALAAGDRVKAVASAVQAVRHEGGVLLITDADALLPAAA
EPVASLILSELRTAVATAGVVLIATSARPDQLDARLRSPELCDRELGLPLPDAATRKSLLEALLNPVPTGDLNLDEIASR
TPGFVVADLAALVREAALRAASRASADGRPPMLHQDDLLGALTVIRPLSRSASDEVTVGDVTLDDVGDMAAAKQALTEAV
LWPLQHPDTFARLGVEPPRGVLLYGPPGCGKTFVVRALASTGQLSVHAVKGSELMDKWVGSSEKAVRELFRRARDSAPSL
VFLDELDALAPRRGQSFDSGVSDRVVAALLTELDGIDPLRDVVMLGATNRPDLIDPALLRPGRLERLVFVEPPDAAARRE
ILRTAGKSIPLSSDVDLDEVAAGLDGYSAADCVALLREAALTAMRRSIDAANVTAADLATARETVRASLDPLQVASLRKF
GTKGDLRS
>Mature_727_residues
THPDPARQLTLTARLNTSAVDSRRGVVRLHPNAIAALGIREWDAVSLTGSRTTAAVAGLAAADTAVGTVLLDDVTLSNAG
LREGTEVIVSPVTVYGARSVTLSGSTLATQSVPPVTLRQALLGKVMTVGDAVSLLPRDLGPGTSTSAASRALAAAVGISW
TSELLTVTGVDPDGPVSVQPNSLVTWGAGVPAAMGTSTAGQVSISSPEIQIEELKGAQPQAAKLTEWLKLALDEPHLLQT
LGAGTNLGVLVSGPAGVGKATLVRAVCDGRRLVTLDGPEIGALAAGDRVKAVASAVQAVRHEGGVLLITDADALLPAAAE
PVASLILSELRTAVATAGVVLIATSARPDQLDARLRSPELCDRELGLPLPDAATRKSLLEALLNPVPTGDLNLDEIASRT
PGFVVADLAALVREAALRAASRASADGRPPMLHQDDLLGALTVIRPLSRSASDEVTVGDVTLDDVGDMAAAKQALTEAVL
WPLQHPDTFARLGVEPPRGVLLYGPPGCGKTFVVRALASTGQLSVHAVKGSELMDKWVGSSEKAVRELFRRARDSAPSLV
FLDELDALAPRRGQSFDSGVSDRVVAALLTELDGIDPLRDVVMLGATNRPDLIDPALLRPGRLERLVFVEPPDAAARREI
LRTAGKSIPLSSDVDLDEVAAGLDGYSAADCVALLREAALTAMRRSIDAANVTAADLATARETVRASLDPLQVASLRKFG
TKGDLRS

Specific function: Seems To Act As An ATP-Dependent Zinc Metallopeptidase. Involved In The Degradation Of Sigma-32. Degrades Carboxy- Terminal-Tagged Cytoplasmic Proteins. These Proteins Are Tagged With An 11-Amino-Acid Nonpolar Destabilizing Tail VIa A Mechanism Involving

COG id: COG0464

COG function: function code O; ATPases of the AAA+ class

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AAA ATPase family. CDC48 subfamily [H]

Homologues:

Organism=Homo sapiens, GI157671927, Length=532, Percent_Identity=40.6015037593985, Blast_Score=355, Evalue=7e-98,
Organism=Homo sapiens, GI6005942, Length=698, Percent_Identity=31.3753581661891, Blast_Score=294, Evalue=2e-79,
Organism=Homo sapiens, GI45643125, Length=556, Percent_Identity=36.5107913669065, Blast_Score=285, Evalue=1e-76,
Organism=Homo sapiens, GI45643123, Length=556, Percent_Identity=36.5107913669065, Blast_Score=284, Evalue=2e-76,
Organism=Homo sapiens, GI229577436, Length=508, Percent_Identity=36.0236220472441, Blast_Score=281, Evalue=2e-75,
Organism=Homo sapiens, GI4505725, Length=483, Percent_Identity=35.8178053830228, Blast_Score=244, Evalue=2e-64,
Organism=Homo sapiens, GI194018488, Length=478, Percent_Identity=36.1924686192469, Blast_Score=210, Evalue=5e-54,
Organism=Homo sapiens, GI24497618, Length=261, Percent_Identity=39.8467432950192, Blast_Score=189, Evalue=6e-48,
Organism=Homo sapiens, GI5729991, Length=251, Percent_Identity=39.8406374501992, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI24430155, Length=251, Percent_Identity=39.8406374501992, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI195539395, Length=301, Percent_Identity=36.5448504983389, Blast_Score=188, Evalue=2e-47,
Organism=Homo sapiens, GI89064750, Length=251, Percent_Identity=39.8406374501992, Blast_Score=188, Evalue=2e-47,
Organism=Homo sapiens, GI24430151, Length=246, Percent_Identity=39.8373983739837, Blast_Score=187, Evalue=3e-47,
Organism=Homo sapiens, GI153792536, Length=232, Percent_Identity=43.1034482758621, Blast_Score=186, Evalue=7e-47,
Organism=Homo sapiens, GI21361144, Length=224, Percent_Identity=39.2857142857143, Blast_Score=181, Evalue=2e-45,
Organism=Homo sapiens, GI5901990, Length=238, Percent_Identity=41.5966386554622, Blast_Score=176, Evalue=5e-44,
Organism=Homo sapiens, GI24497435, Length=247, Percent_Identity=37.6518218623482, Blast_Score=176, Evalue=8e-44,
Organism=Homo sapiens, GI4506209, Length=231, Percent_Identity=40.6926406926407, Blast_Score=175, Evalue=1e-43,
Organism=Homo sapiens, GI300192933, Length=269, Percent_Identity=36.8029739776952, Blast_Score=170, Evalue=4e-42,
Organism=Homo sapiens, GI21327685, Length=256, Percent_Identity=37.5, Blast_Score=168, Evalue=2e-41,
Organism=Homo sapiens, GI7657689, Length=256, Percent_Identity=37.5, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI14149767, Length=237, Percent_Identity=40.5063291139241, Blast_Score=167, Evalue=3e-41,
Organism=Homo sapiens, GI62177112, Length=237, Percent_Identity=40.5063291139241, Blast_Score=167, Evalue=3e-41,
Organism=Homo sapiens, GI156564401, Length=230, Percent_Identity=39.1304347826087, Blast_Score=159, Evalue=8e-39,
Organism=Homo sapiens, GI310125280, Length=230, Percent_Identity=39.1304347826087, Blast_Score=159, Evalue=9e-39,
Organism=Homo sapiens, GI310125282, Length=230, Percent_Identity=39.1304347826087, Blast_Score=158, Evalue=2e-38,
Organism=Homo sapiens, GI4507173, Length=247, Percent_Identity=37.246963562753, Blast_Score=157, Evalue=4e-38,
Organism=Homo sapiens, GI7019569, Length=255, Percent_Identity=34.1176470588235, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI31742536, Length=264, Percent_Identity=35.2272727272727, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI112789543, Length=264, Percent_Identity=35.2272727272727, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI17865802, Length=255, Percent_Identity=33.3333333333333, Blast_Score=146, Evalue=6e-35,
Organism=Homo sapiens, GI226371754, Length=264, Percent_Identity=32.9545454545455, Blast_Score=143, Evalue=5e-34,
Organism=Homo sapiens, GI40806170, Length=265, Percent_Identity=34.3396226415094, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI11875211, Length=265, Percent_Identity=34.3396226415094, Blast_Score=137, Evalue=3e-32,
Organism=Homo sapiens, GI31377644, Length=265, Percent_Identity=32.8301886792453, Blast_Score=132, Evalue=9e-31,
Organism=Homo sapiens, GI64084766, Length=224, Percent_Identity=29.9107142857143, Blast_Score=97, Evalue=4e-20,
Organism=Homo sapiens, GI40806173, Length=138, Percent_Identity=37.6811594202899, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI116292174, Length=244, Percent_Identity=29.0983606557377, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1789568, Length=226, Percent_Identity=38.9380530973451, Blast_Score=173, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI17532375, Length=712, Percent_Identity=31.4606741573034, Blast_Score=310, Evalue=2e-84,
Organism=Caenorhabditis elegans, GI17531535, Length=691, Percent_Identity=31.2590448625181, Blast_Score=302, Evalue=3e-82,
Organism=Caenorhabditis elegans, GI17537217, Length=573, Percent_Identity=32.4607329842932, Blast_Score=268, Evalue=7e-72,
Organism=Caenorhabditis elegans, GI17508053, Length=460, Percent_Identity=37.8260869565217, Blast_Score=258, Evalue=1e-68,
Organism=Caenorhabditis elegans, GI25153574, Length=481, Percent_Identity=31.6008316008316, Blast_Score=217, Evalue=2e-56,
Organism=Caenorhabditis elegans, GI17562804, Length=482, Percent_Identity=28.6307053941909, Blast_Score=196, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI71987364, Length=299, Percent_Identity=37.7926421404682, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI71987372, Length=299, Percent_Identity=37.7926421404682, Blast_Score=194, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI193209502, Length=225, Percent_Identity=43.1111111111111, Blast_Score=194, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17563250, Length=246, Percent_Identity=40.2439024390244, Blast_Score=184, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17554784, Length=315, Percent_Identity=35.8730158730159, Blast_Score=184, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI17508701, Length=246, Percent_Identity=38.2113821138211, Blast_Score=183, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17563248, Length=229, Percent_Identity=43.2314410480349, Blast_Score=177, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI25144278, Length=247, Percent_Identity=38.0566801619433, Blast_Score=177, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI25144281, Length=247, Percent_Identity=38.0566801619433, Blast_Score=176, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17554786, Length=247, Percent_Identity=37.6518218623482, Blast_Score=176, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI193206116, Length=236, Percent_Identity=41.5254237288136, Blast_Score=174, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI133931034, Length=236, Percent_Identity=41.5254237288136, Blast_Score=173, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI193206114, Length=236, Percent_Identity=41.5254237288136, Blast_Score=173, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17508421, Length=256, Percent_Identity=39.0625, Blast_Score=162, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI32563584, Length=258, Percent_Identity=38.7596899224806, Blast_Score=162, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI17505546, Length=226, Percent_Identity=35.8407079646018, Blast_Score=160, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI25146157, Length=278, Percent_Identity=35.6115107913669, Blast_Score=156, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI86561515, Length=255, Percent_Identity=34.1176470588235, Blast_Score=156, Evalue=4e-38,
Organism=Caenorhabditis elegans, GI17554264, Length=237, Percent_Identity=37.1308016877637, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI133901662, Length=225, Percent_Identity=36, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI133901658, Length=225, Percent_Identity=36, Blast_Score=140, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17560432, Length=275, Percent_Identity=35.6363636363636, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI115534323, Length=278, Percent_Identity=32.7338129496403, Blast_Score=133, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71994521, Length=260, Percent_Identity=34.2307692307692, Blast_Score=124, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17541224, Length=219, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17541226, Length=219, Percent_Identity=33.3333333333333, Blast_Score=122, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6323429, Length=528, Percent_Identity=35.9848484848485, Blast_Score=307, Evalue=3e-84,
Organism=Saccharomyces cerevisiae, GI6320077, Length=586, Percent_Identity=33.9590443686007, Blast_Score=297, Evalue=4e-81,
Organism=Saccharomyces cerevisiae, GI6322994, Length=260, Percent_Identity=43.8461538461538, Blast_Score=229, Evalue=8e-61,
Organism=Saccharomyces cerevisiae, GI6324000, Length=496, Percent_Identity=31.0483870967742, Blast_Score=196, Evalue=1e-50,
Organism=Saccharomyces cerevisiae, GI6322651, Length=366, Percent_Identity=32.2404371584699, Blast_Score=194, Evalue=3e-50,
Organism=Saccharomyces cerevisiae, GI6321390, Length=308, Percent_Identity=36.038961038961, Blast_Score=193, Evalue=7e-50,
Organism=Saccharomyces cerevisiae, GI6320602, Length=234, Percent_Identity=43.1623931623932, Blast_Score=185, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6320197, Length=246, Percent_Identity=37.8048780487805, Blast_Score=183, Evalue=9e-47,
Organism=Saccharomyces cerevisiae, GI6321709, Length=236, Percent_Identity=40.6779661016949, Blast_Score=182, Evalue=2e-46,
Organism=Saccharomyces cerevisiae, GI6324833, Length=262, Percent_Identity=36.6412213740458, Blast_Score=181, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6322704, Length=231, Percent_Identity=39.8268398268398, Blast_Score=168, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6323736, Length=263, Percent_Identity=36.1216730038023, Blast_Score=162, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6325281, Length=251, Percent_Identity=36.2549800796813, Blast_Score=157, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6324691, Length=226, Percent_Identity=35.8407079646018, Blast_Score=153, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6325431, Length=249, Percent_Identity=34.9397590361446, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6319554, Length=245, Percent_Identity=35.1020408163265, Blast_Score=150, Evalue=6e-37,
Organism=Saccharomyces cerevisiae, GI6320854, Length=261, Percent_Identity=35.632183908046, Blast_Score=149, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6321465, Length=237, Percent_Identity=36.7088607594937, Blast_Score=140, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6325183, Length=320, Percent_Identity=30.9375, Blast_Score=133, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6320887, Length=299, Percent_Identity=31.1036789297659, Blast_Score=126, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6320583, Length=164, Percent_Identity=28.0487804878049, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17137560, Length=507, Percent_Identity=35.3057199211045, Blast_Score=298, Evalue=6e-81,
Organism=Drosophila melanogaster, GI161076488, Length=507, Percent_Identity=35.3057199211045, Blast_Score=298, Evalue=6e-81,
Organism=Drosophila melanogaster, GI161076486, Length=507, Percent_Identity=35.3057199211045, Blast_Score=298, Evalue=8e-81,
Organism=Drosophila melanogaster, GI19921202, Length=498, Percent_Identity=37.14859437751, Blast_Score=293, Evalue=2e-79,
Organism=Drosophila melanogaster, GI24660075, Length=283, Percent_Identity=43.1095406360424, Blast_Score=238, Evalue=1e-62,
Organism=Drosophila melanogaster, GI281365776, Length=283, Percent_Identity=43.1095406360424, Blast_Score=237, Evalue=2e-62,
Organism=Drosophila melanogaster, GI45552965, Length=283, Percent_Identity=43.1095406360424, Blast_Score=237, Evalue=2e-62,
Organism=Drosophila melanogaster, GI24656825, Length=504, Percent_Identity=31.547619047619, Blast_Score=222, Evalue=8e-58,
Organism=Drosophila melanogaster, GI24656820, Length=439, Percent_Identity=33.7129840546697, Blast_Score=222, Evalue=8e-58,
Organism=Drosophila melanogaster, GI21355121, Length=510, Percent_Identity=30.9803921568627, Blast_Score=219, Evalue=6e-57,
Organism=Drosophila melanogaster, GI18860063, Length=233, Percent_Identity=42.0600858369099, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI281363136, Length=306, Percent_Identity=40.1960784313725, Blast_Score=193, Evalue=4e-49,
Organism=Drosophila melanogaster, GI78707192, Length=306, Percent_Identity=40.1960784313725, Blast_Score=193, Evalue=4e-49,
Organism=Drosophila melanogaster, GI24652279, Length=198, Percent_Identity=44.9494949494949, Blast_Score=189, Evalue=4e-48,
Organism=Drosophila melanogaster, GI281361487, Length=250, Percent_Identity=38.8, Blast_Score=189, Evalue=6e-48,
Organism=Drosophila melanogaster, GI24649446, Length=246, Percent_Identity=40.2439024390244, Blast_Score=187, Evalue=2e-47,
Organism=Drosophila melanogaster, GI24640100, Length=300, Percent_Identity=37, Blast_Score=186, Evalue=6e-47,
Organism=Drosophila melanogaster, GI17738151, Length=246, Percent_Identity=38.6178861788618, Blast_Score=184, Evalue=1e-46,
Organism=Drosophila melanogaster, GI24651451, Length=267, Percent_Identity=37.0786516853933, Blast_Score=183, Evalue=4e-46,
Organism=Drosophila melanogaster, GI19920408, Length=246, Percent_Identity=38.2113821138211, Blast_Score=183, Evalue=5e-46,
Organism=Drosophila melanogaster, GI24663015, Length=313, Percent_Identity=35.7827476038339, Blast_Score=182, Evalue=6e-46,
Organism=Drosophila melanogaster, GI17137738, Length=231, Percent_Identity=41.5584415584416, Blast_Score=177, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24658770, Length=247, Percent_Identity=40.080971659919, Blast_Score=169, Evalue=7e-42,
Organism=Drosophila melanogaster, GI24639391, Length=251, Percent_Identity=37.4501992031873, Blast_Score=157, Evalue=2e-38,
Organism=Drosophila melanogaster, GI24644145, Length=233, Percent_Identity=39.9141630901288, Blast_Score=156, Evalue=5e-38,
Organism=Drosophila melanogaster, GI28574878, Length=253, Percent_Identity=35.5731225296443, Blast_Score=149, Evalue=5e-36,
Organism=Drosophila melanogaster, GI24665814, Length=253, Percent_Identity=35.5731225296443, Blast_Score=149, Evalue=5e-36,
Organism=Drosophila melanogaster, GI17864540, Length=223, Percent_Identity=39.4618834080717, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI28573010, Length=236, Percent_Identity=37.2881355932203, Blast_Score=148, Evalue=1e-35,
Organism=Drosophila melanogaster, GI18859657, Length=229, Percent_Identity=35.8078602620087, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI281360146, Length=280, Percent_Identity=33.9285714285714, Blast_Score=142, Evalue=9e-34,
Organism=Drosophila melanogaster, GI281360138, Length=280, Percent_Identity=33.9285714285714, Blast_Score=142, Evalue=9e-34,
Organism=Drosophila melanogaster, GI281360144, Length=280, Percent_Identity=33.9285714285714, Blast_Score=142, Evalue=1e-33,
Organism=Drosophila melanogaster, GI281360140, Length=280, Percent_Identity=33.9285714285714, Blast_Score=142, Evalue=1e-33,
Organism=Drosophila melanogaster, GI281360142, Length=280, Percent_Identity=33.9285714285714, Blast_Score=142, Evalue=1e-33,
Organism=Drosophila melanogaster, GI21357333, Length=280, Percent_Identity=33.9285714285714, Blast_Score=142, Evalue=1e-33,
Organism=Drosophila melanogaster, GI281360136, Length=280, Percent_Identity=33.9285714285714, Blast_Score=142, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24644411, Length=280, Percent_Identity=33.9285714285714, Blast_Score=142, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24581396, Length=230, Percent_Identity=36.9565217391304, Blast_Score=139, Evalue=9e-33,
Organism=Drosophila melanogaster, GI20129423, Length=272, Percent_Identity=31.25, Blast_Score=133, Evalue=4e-31,
Organism=Drosophila melanogaster, GI28571849, Length=291, Percent_Identity=35.0515463917526, Blast_Score=129, Evalue=6e-30,
Organism=Drosophila melanogaster, GI28571847, Length=291, Percent_Identity=35.0515463917526, Blast_Score=129, Evalue=6e-30,
Organism=Drosophila melanogaster, GI24639486, Length=229, Percent_Identity=35.8078602620087, Blast_Score=128, Evalue=2e-29,
Organism=Drosophila melanogaster, GI20129529, Length=232, Percent_Identity=33.1896551724138, Blast_Score=127, Evalue=3e-29,
Organism=Drosophila melanogaster, GI45554047, Length=167, Percent_Identity=37.7245508982036, Blast_Score=120, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR003593
- InterPro:   IPR005938
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR003338
- InterPro:   IPR004201
- InterPro:   IPR015415 [H]

Pfam domain/function: PF00004 AAA; PF02933 CDC48_2; PF02359 CDC48_N; PF09336 Vps4_C [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 75347; Mature: 75216

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS00674 AAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHPDPARQLTLTARLNTSAVDSRRGVVRLHPNAIAALGIREWDAVSLTGSRTTAAVAGL
CCCCCCCCEEEEEEECCCHHHHCCCCEEEECCCEEEEECCCCCCEEEECCCCHHHHHHHH
AAADTAVGTVLLDDVTLSNAGLREGTEVIVSPVTVYGARSVTLSGSTLATQSVPPVTLRQ
HHHHHHHHEEEEECEEECCCCCCCCCEEEEECEEEECCEEEEECCCEEECCCCCCHHHHH
ALLGKVMTVGDAVSLLPRDLGPGTSTSAASRALAAAVGISWTSELLTVTGVDPDGPVSVQ
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEC
PNSLVTWGAGVPAAMGTSTAGQVSISSPEIQIEELKGAQPQAAKLTEWLKLALDEPHLLQ
CCCEEEECCCCCHHCCCCCCCEEEECCCCEEHHHHCCCCCHHHHHHHHHHHHCCCCHHHH
TLGAGTNLGVLVSGPAGVGKATLVRAVCDGRRLVTLDGPEIGALAAGDRVKAVASAVQAV
HHCCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHH
RHEGGVLLITDADALLPAAAEPVASLILSELRTAVATAGVVLIATSARPDQLDARLRSPE
HHCCCEEEEECCHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHCCCCC
LCDRELGLPLPDAATRKSLLEALLNPVPTGDLNLDEIASRTPGFVVADLAALVREAALRA
HHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHH
ASRASADGRPPMLHQDDLLGALTVIRPLSRSASDEVTVGDVTLDDVGDMAAAKQALTEAV
HHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCEEHHHHHHHHHHHHHHHHHH
LWPLQHPDTFARLGVEPPRGVLLYGPPGCGKTFVVRALASTGQLSVHAVKGSELMDKWVG
HCCCCCCCHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHCC
SSEKAVRELFRRARDSAPSLVFLDELDALAPRRGQSFDSGVSDRVVAALLTELDGIDPLR
CCHHHHHHHHHHHHCCCCCEEEEHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHH
DVVMLGATNRPDLIDPALLRPGRLERLVFVEPPDAAARREILRTAGKSIPLSSDVDLDEV
HHHHCCCCCCCCCCCHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCHHHH
AAGLDGYSAADCVALLREAALTAMRRSIDAANVTAADLATARETVRASLDPLQVASLRKF
HHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHC
GTKGDLRS
CCCCCCCC
>Mature Secondary Structure 
THPDPARQLTLTARLNTSAVDSRRGVVRLHPNAIAALGIREWDAVSLTGSRTTAAVAGL
CCCCCCCEEEEEEECCCHHHHCCCCEEEECCCEEEEECCCCCCEEEECCCCHHHHHHHH
AAADTAVGTVLLDDVTLSNAGLREGTEVIVSPVTVYGARSVTLSGSTLATQSVPPVTLRQ
HHHHHHHHEEEEECEEECCCCCCCCCEEEEECEEEECCEEEEECCCEEECCCCCCHHHHH
ALLGKVMTVGDAVSLLPRDLGPGTSTSAASRALAAAVGISWTSELLTVTGVDPDGPVSVQ
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCEEEC
PNSLVTWGAGVPAAMGTSTAGQVSISSPEIQIEELKGAQPQAAKLTEWLKLALDEPHLLQ
CCCEEEECCCCCHHCCCCCCCEEEECCCCEEHHHHCCCCCHHHHHHHHHHHHCCCCHHHH
TLGAGTNLGVLVSGPAGVGKATLVRAVCDGRRLVTLDGPEIGALAAGDRVKAVASAVQAV
HHCCCCCCEEEEECCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHH
RHEGGVLLITDADALLPAAAEPVASLILSELRTAVATAGVVLIATSARPDQLDARLRSPE
HHCCCEEEEECCHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHCCCCC
LCDRELGLPLPDAATRKSLLEALLNPVPTGDLNLDEIASRTPGFVVADLAALVREAALRA
HHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHH
ASRASADGRPPMLHQDDLLGALTVIRPLSRSASDEVTVGDVTLDDVGDMAAAKQALTEAV
HHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEECCEEHHHHHHHHHHHHHHHHHH
LWPLQHPDTFARLGVEPPRGVLLYGPPGCGKTFVVRALASTGQLSVHAVKGSELMDKWVG
HCCCCCCCHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEEEECCHHHHHHHCC
SSEKAVRELFRRARDSAPSLVFLDELDALAPRRGQSFDSGVSDRVVAALLTELDGIDPLR
CCHHHHHHHHHHHHCCCCCEEEEHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHH
DVVMLGATNRPDLIDPALLRPGRLERLVFVEPPDAAARREILRTAGKSIPLSSDVDLDEV
HHHHCCCCCCCCCCCHHHCCCCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCHHHH
AAGLDGYSAADCVALLREAALTAMRRSIDAANVTAADLATARETVRASLDPLQVASLRKF
HHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHC
GTKGDLRS
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]