Click here to switch to the map view.

The map label for this gene is lpqK [C]

Identifier: 121636311

GI number: 121636311

Start: 508142

End: 509371

Strand: Reverse

Name: lpqK [C]

Synonym: BCG_0436c

Alternate gene names: 121636311

Gene position: 509371-508142 (Counterclockwise)

Preceding gene: 121636312

Following gene: 121636310

Centisome position: 11.64

GC content: 64.55

Gene sequence:

>1230_bases
ATGCCCGTCTTGCGGCGCCTCGGGTGTTCGGTCCTGGCTCTCGGGCTGCTGGCCGGCTGCGCCCCACCCCGCACCGGGCC
GGCTTCGTCGCCGACCAACAACGGGGCCAAGGCCGACGCGGTCATCCGGATTGTGCGTGACTTCATGACGCAAGCGCATC
TGAAGGCGGTGCTGGTCCGGGTCACCGTGGCCGGCAAGGAGGTCGTGACGCGGGCCGTCGGCGACTCGATGACCGGCGTG
CCGGCCACCACCGCCATGCACTTTCGCAACGGCGCGGTCGCAATCTCCTATGTCGCGACGCTGTTGCTCAAACTGGTCGA
CGAAAAAAAGCTGCGCCTGGACGACAAGCTGTCCAGGTGGCTTCCCGACTTTCCGCACGCCGACCGGGTCACGCTGGGTC
AACTAGCGCAGATGACATCCGGCTACCCCGACTACGTCCTCGGCAACGAGGCGTTTGATGCCGAGCTTTACGCTAATCCG
TTCCGGCAGTGGACAACACAAGAGTTACTCGATCAAATCTCTTCACGGCCACTGCTTTACGACCCGGGCACCAACTGGAA
CTACGCGCACACCAATTACCTCTTGCTGGGGCTGGCGTTGGAGAAGGCCGCCGGCCAAGACATGCCAACCCTGCTGCAGC
GCAAGGTCCTTTCCCCCCTGGGCCTCACGGCCACCGCCAACTCCGATACCCCCGCCATCCCCGAGCCCGCCTTGCATGCA
TTCACCTCCGAGCGCCGAGCGGCCTTGAAAATTCCTGCCGGCGTGCCGTTTTACGAGGAATCGACCTTCTGGAATCCGTC
GTGGACCATCACCCACGGCGCCATCCAAACCACCACCATCTACGACATGGAGGCCACCGCGGTGGGGATCGGGTCGGGCA
GGCTGCTCTCGGCGGATTCGTACAAGAAGATGGTGTCGACCGAGCTGCGCGGCAAGACCCGCGCCCAGCCGGGCTGCCCC
ACCTGCTTCGAGCAGAACGACGGCTACAGCTATGGTCTCGGGATCGTCATATCCGGCCATTGGCTGCTGCAAAATCCCAT
GTTCGCCGGTTACGCCGCGGTGGAGGCCTATCTGCCGTCGCAACGGGTCGCGGTGGCGGTCGCAGTCACCTACGCCCCCG
AGGCCTTCGATGACCAGGGCAACTACCGCAACCAGGCCGACATACTATTTCGCAAGATCGGTGCCGAGGTAGCACCGAAC
GACGCCCCACCCATGCCGCCGGGGAGGTAG

Upstream 100 bases:

>100_bases
CCTGGAGTCGGTGCTCACCTACGAGGGCACGCCCGAGATGCATCAGCTGGTGCTCGGTCAGGCCTTCACGGGCTTGGCCG
CCTTCCGGTAGGACCGTCGC

Downstream 100 bases:

>100_bases
GTAGCCATGGGAGTCATTGCCCGCGTTGTCGGTGTCGCCGCGTGCGGTTTGTCCCTGGCCGTGCTGGCCGCCGCGCCCAC
CGCGGGCGCGGAACCCACCG

Product: putative lipoprotein lpqK

Products: NA

Alternate protein names: DD-carboxypeptidase; DD-peptidase [H]

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MPVLRRLGCSVLALGLLAGCAPPRTGPASSPTNNGAKADAVIRIVRDFMTQAHLKAVLVRVTVAGKEVVTRAVGDSMTGV
PATTAMHFRNGAVAISYVATLLLKLVDEKKLRLDDKLSRWLPDFPHADRVTLGQLAQMTSGYPDYVLGNEAFDAELYANP
FRQWTTQELLDQISSRPLLYDPGTNWNYAHTNYLLLGLALEKAAGQDMPTLLQRKVLSPLGLTATANSDTPAIPEPALHA
FTSERRAALKIPAGVPFYEESTFWNPSWTITHGAIQTTTIYDMEATAVGIGSGRLLSADSYKKMVSTELRGKTRAQPGCP
TCFEQNDGYSYGLGIVISGHWLLQNPMFAGYAAVEAYLPSQRVAVAVAVTYAPEAFDDQGNYRNQADILFRKIGAEVAPN
DAPPMPPGR

Sequences:

>Translated_409_residues
MPVLRRLGCSVLALGLLAGCAPPRTGPASSPTNNGAKADAVIRIVRDFMTQAHLKAVLVRVTVAGKEVVTRAVGDSMTGV
PATTAMHFRNGAVAISYVATLLLKLVDEKKLRLDDKLSRWLPDFPHADRVTLGQLAQMTSGYPDYVLGNEAFDAELYANP
FRQWTTQELLDQISSRPLLYDPGTNWNYAHTNYLLLGLALEKAAGQDMPTLLQRKVLSPLGLTATANSDTPAIPEPALHA
FTSERRAALKIPAGVPFYEESTFWNPSWTITHGAIQTTTIYDMEATAVGIGSGRLLSADSYKKMVSTELRGKTRAQPGCP
TCFEQNDGYSYGLGIVISGHWLLQNPMFAGYAAVEAYLPSQRVAVAVAVTYAPEAFDDQGNYRNQADILFRKIGAEVAPN
DAPPMPPGR
>Mature_408_residues
PVLRRLGCSVLALGLLAGCAPPRTGPASSPTNNGAKADAVIRIVRDFMTQAHLKAVLVRVTVAGKEVVTRAVGDSMTGVP
ATTAMHFRNGAVAISYVATLLLKLVDEKKLRLDDKLSRWLPDFPHADRVTLGQLAQMTSGYPDYVLGNEAFDAELYANPF
RQWTTQELLDQISSRPLLYDPGTNWNYAHTNYLLLGLALEKAAGQDMPTLLQRKVLSPLGLTATANSDTPAIPEPALHAF
TSERRAALKIPAGVPFYEESTFWNPSWTITHGAIQTTTIYDMEATAVGIGSGRLLSADSYKKMVSTELRGKTRAQPGCPT
CFEQNDGYSYGLGIVISGHWLLQNPMFAGYAAVEAYLPSQRVAVAVAVTYAPEAFDDQGNYRNQADILFRKIGAEVAPND
APPMPPGR

Specific function: Catalyzes distinct carboxypeptidation and transpeptidation reactions during the last stages of wall peptidoglycan synthesis. Mistaking a beta-lactam antibiotic molecule for a normal substrate (i.e., a D-alanyl-D-alanine- terminated peptide), it becomes im

COG id: COG1680

COG function: function code V; Beta-lactamase class C and other penicillin binding proteins

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S12 family [H]

Homologues:

Organism=Escherichia coli, GI87082101, Length=179, Percent_Identity=27.3743016759777, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.4.16.4 [H]

Molecular weight: Translated: 44309; Mature: 44178

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVLRRLGCSVLALGLLAGCAPPRTGPASSPTNNGAKADAVIRIVRDFMTQAHLKAVLVR
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VTVAGKEVVTRAVGDSMTGVPATTAMHFRNGAVAISYVATLLLKLVDEKKLRLDDKLSRW
EEECCHHHHHHHHCCCCCCCCCHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPDFPHADRVTLGQLAQMTSGYPDYVLGNEAFDAELYANPFRQWTTQELLDQISSRPLLY
CCCCCCCCCCHHHHHHHHHCCCCCCEECCCCCCHHHHHCHHHHHHHHHHHHHHHCCCEEE
DPGTNWNYAHTNYLLLGLALEKAAGQDMPTLLQRKVLSPLGLTATANSDTPAIPEPALHA
CCCCCCCCCCCCEEEEEEHHHHHCCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHH
FTSERRAALKIPAGVPFYEESTFWNPSWTITHGAIQTTTIYDMEATAVGIGSGRLLSADS
HHHCCCEEEECCCCCCCCCCCCEECCCEEEEECCEEEEEEEEEEEEEEECCCCCEECCHH
YKKMVSTELRGKTRAQPGCPTCFEQNDGYSYGLGIVISGHWLLQNPMFAGYAAVEAYLPS
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCEEECCCCHHHHHHHHHHCCC
QRVAVAVAVTYAPEAFDDQGNYRNQADILFRKIGAEVAPNDAPPMPPGR
CCEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PVLRRLGCSVLALGLLAGCAPPRTGPASSPTNNGAKADAVIRIVRDFMTQAHLKAVLVR
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VTVAGKEVVTRAVGDSMTGVPATTAMHFRNGAVAISYVATLLLKLVDEKKLRLDDKLSRW
EEECCHHHHHHHHCCCCCCCCCHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LPDFPHADRVTLGQLAQMTSGYPDYVLGNEAFDAELYANPFRQWTTQELLDQISSRPLLY
CCCCCCCCCCHHHHHHHHHCCCCCCEECCCCCCHHHHHCHHHHHHHHHHHHHHHCCCEEE
DPGTNWNYAHTNYLLLGLALEKAAGQDMPTLLQRKVLSPLGLTATANSDTPAIPEPALHA
CCCCCCCCCCCCEEEEEEHHHHHCCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCHHHHH
FTSERRAALKIPAGVPFYEESTFWNPSWTITHGAIQTTTIYDMEATAVGIGSGRLLSADS
HHHCCCEEEECCCCCCCCCCCCEECCCEEEEECCEEEEEEEEEEEEEEECCCCCEECCHH
YKKMVSTELRGKTRAQPGCPTCFEQNDGYSYGLGIVISGHWLLQNPMFAGYAAVEAYLPS
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCEEECCCCHHHHHHHHHHCCC
QRVAVAVAVTYAPEAFDDQGNYRNQADILFRKIGAEVAPNDAPPMPPGR
CCEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3830154; 7925404; 3030739; 2175384; 2386365; 3997832; 7490745 [H]