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The map label for this gene is mmpL3 [H]

Identifier: 121636118

GI number: 121636118

Start: 274387

End: 277221

Strand: Reverse

Name: mmpL3 [H]

Synonym: BCG_0243c

Alternate gene names: 121636118

Gene position: 277221-274387 (Counterclockwise)

Preceding gene: 121636119

Following gene: 121636116

Centisome position: 6.34

GC content: 65.29

Gene sequence:

>2835_bases
GTGTTCGCCTGGTGGGGTCGAACTGTGTACCGCTACCGGTTCATCGTAATCGGGGTCATGGTCGCTCTATGCCTCGGCGG
CGGCGTTTTCGGGCTGAGCCTCGGCAAGCACGTCACGCAGAGCGGCTTCTACGACGACGGCAGCCAATCGGTGCAAGCAT
CGGTGCTGGGCGACCAGGTCTACGGCCGAGACCGAAGCGGTCACATCGTCGCGATCTTCCAAGCCCCAGCCGGCAAGACC
GTTGACGACCCGGCCTGGTCAAAGAAGGTCGTCGACGAGCTCAACCGGTTCCAGCAGGATCACCCCGACCAGGTCTTGGG
ATGGGCCGGCTACCTGAGAGCGAGTCAGGCGACCGGCATGGCCACCGCCGACAAGAAGTACACCTTCGTTTCCATCCCGC
TCAAGGGTGATGACGACGACACCATCCTCAACAACTACAAGGCCATCGCACCCGACCTGCAGCGGCTCGACGGAGGCACG
GTGAAGCTCGCCGGGCTGCAACCGGTGGCCGAGGCGTTGACCGGCACCATCGCCACCGACCAACGGCGAATGGAAGTGCT
GGCGCTGCCGTTGGTGGCGGTGGTGTTGTTCTTCGTGTTCGGCGGCGTGATCGCCGCCGGCCTACCGGTGATGGTCGGAG
GGCTGTGCATCGCCGGCGCGCTGGGCATCATGCGGTTCCTCGCGATCTTCGGTCCCGTGCACTATTTCGCCCAGCCCGTG
GTGTCGCTGATCGGTCTGGGGATCGCCATCGACTACGGGTTGTTCATCGTGAGCCGGTTCCGCGAAGAGATCGCCGAAGG
CTACGACACCGAGACGGCAGTACGGCGCACGGTGATCACCGCCGGACGCACGGTGACGTTCTCGGCGGTGTTGATCGTCG
CGTCGGCGATCGGTCTGCTGCTCTTCCCGCAGGGTTTCCTGAAGTCGCTGACCTACGCCACGATCGCATCGGTGATGCTG
TCGGCCATCCTGTCTATCACCGTGTTGCCGGCCTGTCTGGGGATCCTGGGCAAACACGTCGACGCGCTCGGCGTGCGGAC
CCTGTTCCGGGTGCCCTTCCTGGCGAACTGGAAGATTTCGGCCGCCTACCTGAACTGGCTCGCCGACCGCCTGCAGCGGA
CCAAGACCCGCGAAGAGGTCGAAGCCGGCATCTGGGGCAAGCTGGTTAACCGGGTGATGAAGCGCCCAGTGCTGTTCGCC
GCACCGATCGTCATCATCATGATTTTGCTGATTATCCCGGTGGGCAAGCTGTCATTGGGCGGGATCAGCGAGAAGTACTT
GCCGCCGACCAATTCGGTGCGCCAGGCGCAGGAGGAGTTCGACAAACTCTTCCCCGGATACCGCACCAATCCGCTGACAC
TGGTGATCCAGACCAGCAACCATCAACCGGTCACCGAGGCGCAGATCGCTGACATCCGCAGCAAGGCGATGGCGATCGGC
GGATTCATCGAGCCGGACAACGATCCGGCGAATATGTGGCAAGAGCGTGCCTACGCGGTAGGCGCATCTAAAGATCCATC
GGTGCGCGTCCTGCAGAACGGGTTGATCAACCCGGCTGACGCGTCGAAGAAGCTCACCGAGCTGCGCGCGATCACCCCGC
CCAAAGGAATCACGGTCTTGGTCGGTGGAACTCCCGCCCTGGAGCTGGATTCAATCCACGGCCTGTTCGCGAAGATGCCG
CTGATGGTGGTCATCCTGCTGACCACCACGATCGTCTTGATGTTCTTGGCGTTCGGCTCGGTGGTGCTGCCAATCAAGGC
GACGCTGATGAGCGCTCTGACGCTCGGGTCCACCATGGGCATCCTGACGTGGATATTCGTCGACGGACACTTTTCGAAGT
GGCTGAATTTCACGCCGACCCCGCTGACAGCGCCGGTGATCGGGCTGATCATCGCGCTGGTCTTCGGCCTATCCACCGAC
TACGAGGTGTTCTTGGTGTCCCGGATGGTCGAGGCGCGAGAGCGCGGCATGTCGACCCAGGAGGCGATCCGGATCGGCAC
CGCAGCCACCGGACGCATCATTACCGCCGCGGCGCTGATTGTTGCCGTCGTCGCGGGCGCGTTCGTGTTCTCCGACCTGG
TGATGATGAAGTATCTGGCCTTTGGACTGATGGCGGCGCTGCTGCTGGACGCGACCGTGGTGCGGATGTTTTTAGTGCCA
TCGGTGATGAAGCTGCTCGGCGATGACTGCTGGTGGGCACCGCGCTGGGCCAGACGCCTGCAGACCCGCATCGGGCTGGG
CGAGATCCACCTGCCCGACGAGCGCAAGCGGCCCGTCAGCAACGGGCGTCCCGCACGTCCTCCGGTCACAGCTGGGCTGG
TTGCGGCGCGCGCCGCTGGGGACCCGCGCCCACCGCACGATCCGACCCATCCGCTGGCGGAGTCACCTCGACCGGCCCGC
TCGAGTCCAGCAAGCTCACCGGAGCTCACGCCTGCCCTGGAAGCAACTGCCGCGCCGGCGGCGCCGTCTGGGGCGAGCAC
CACACGGATGCAGATCGGGTCGTCGACGGAGCCGCCGACAACCCGCCTCGCGGCTGCCGGTCGGTCCGTGCAGTCGCCAG
CATCCACGCCGCCACCAACCCCGACCCCGCCATCGGCCCCGTCTGCCGGTCAGACCCGGGCTATGCCGCTTGCGGCGAAC
CGCTCCACAGACGCAGCCGGTGACCCGGCCGAACCCACCGCGGCCCTGCCAATCATACGGTCGGACGGCGACGACTCAGA
GGCAGCCACTGAGCAGCTGAATGCCCGCGGCACGAGCGATAAGACGCGTCAGCGCCGCCGCGGCGGCGGCGCCCTGTCCG
CCCAGGATCTGCTTCGCCGCGAAGGACGCCTTTAA

Upstream 100 bases:

>100_bases
GGCCGCTGTCCTCGCTGTTGACCTCGCGAGTGTGACAGCCGACGTGTGTGACAACCAAAAAGCAATACGCGGGTCGCTGC
CGATCCAGTAAGGAGCTTAC

Downstream 100 bases:

>100_bases
ACCTCGGTGAGGTGATCGGAAGAAACGTCTGCCACGTCGGCGAACGGATTCCCGCCCAGCAGCACCTGCACCGCATTGTT
GAAGAAAGCGGCCGTCGGGA

Product: transmembrane transport protein mmpL3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 944; Mature: 944

Protein sequence:

>944_residues
MFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQVYGRDRSGHIVAIFQAPAGKT
VDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGMATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGT
VKLAGLQPVAEALTGTIATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV
VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLLLFPQGFLKSLTYATIASVML
SAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKISAAYLNWLADRLQRTKTREEVEAGIWGKLVNRVMKRPVLFA
APIVIIMILLIIPVGKLSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTEAQIADIRSKAMAIG
GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVLVGGTPALELDSIHGLFAKMP
LMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTD
YEVFLVSRMVEARERGMSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP
SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAGDPRPPHDPTHPLAESPRPAR
SSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPTTRLAAAGRSVQSPASTPPPTPTPPSAPSAGQTRAMPLAAN
RSTDAAGDPAEPTAALPIIRSDGDDSEAATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL

Sequences:

>Translated_944_residues
MFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQVYGRDRSGHIVAIFQAPAGKT
VDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGMATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGT
VKLAGLQPVAEALTGTIATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV
VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLLLFPQGFLKSLTYATIASVML
SAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKISAAYLNWLADRLQRTKTREEVEAGIWGKLVNRVMKRPVLFA
APIVIIMILLIIPVGKLSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTEAQIADIRSKAMAIG
GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVLVGGTPALELDSIHGLFAKMP
LMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTD
YEVFLVSRMVEARERGMSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP
SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAGDPRPPHDPTHPLAESPRPAR
SSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPTTRLAAAGRSVQSPASTPPPTPTPPSAPSAGQTRAMPLAAN
RSTDAAGDPAEPTAALPIIRSDGDDSEAATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL
>Mature_944_residues
MFAWWGRTVYRYRFIVIGVMVALCLGGGVFGLSLGKHVTQSGFYDDGSQSVQASVLGDQVYGRDRSGHIVAIFQAPAGKT
VDDPAWSKKVVDELNRFQQDHPDQVLGWAGYLRASQATGMATADKKYTFVSIPLKGDDDDTILNNYKAIAPDLQRLDGGT
VKLAGLQPVAEALTGTIATDQRRMEVLALPLVAVVLFFVFGGVIAAGLPVMVGGLCIAGALGIMRFLAIFGPVHYFAQPV
VSLIGLGIAIDYGLFIVSRFREEIAEGYDTETAVRRTVITAGRTVTFSAVLIVASAIGLLLFPQGFLKSLTYATIASVML
SAILSITVLPACLGILGKHVDALGVRTLFRVPFLANWKISAAYLNWLADRLQRTKTREEVEAGIWGKLVNRVMKRPVLFA
APIVIIMILLIIPVGKLSLGGISEKYLPPTNSVRQAQEEFDKLFPGYRTNPLTLVIQTSNHQPVTEAQIADIRSKAMAIG
GFIEPDNDPANMWQERAYAVGASKDPSVRVLQNGLINPADASKKLTELRAITPPKGITVLVGGTPALELDSIHGLFAKMP
LMVVILLTTTIVLMFLAFGSVVLPIKATLMSALTLGSTMGILTWIFVDGHFSKWLNFTPTPLTAPVIGLIIALVFGLSTD
YEVFLVSRMVEARERGMSTQEAIRIGTAATGRIITAAALIVAVVAGAFVFSDLVMMKYLAFGLMAALLLDATVVRMFLVP
SVMKLLGDDCWWAPRWARRLQTRIGLGEIHLPDERKRPVSNGRPARPPVTAGLVAARAAGDPRPPHDPTHPLAESPRPAR
SSPASSPELTPALEATAAPAAPSGASTTRMQIGSSTEPPTTRLAAAGRSVQSPASTPPPTPTPPSAPSAGQTRAMPLAAN
RSTDAAGDPAEPTAALPIIRSDGDDSEAATEQLNARGTSDKTRQRRRGGGALSAQDLLRREGRL

Specific function: Unknown

COG id: COG2409

COG function: function code R; Predicted drug exporters of the RND superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mmpL family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004869
- InterPro:   IPR000731 [H]

Pfam domain/function: PF03176 MMPL [H]

EC number: NA

Molecular weight: Translated: 100886; Mature: 100886

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS50156 SSD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHCCCC
>Mature Secondary Structure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CCCCCHHHHHHHHHCCCCCHHHHHHHHCCCCCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]