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The map label for this gene is hpsA [H]

Identifier: 121610337

GI number: 121610337

Start: 3776740

End: 3777450

Strand: Direct

Name: hpsA [H]

Synonym: Veis_3405

Alternate gene names: 121610337

Gene position: 3776740-3777450 (Clockwise)

Preceding gene: 121610336

Following gene: 121610338

Centisome position: 67.84

GC content: 69.34

Gene sequence:

>711_bases
GTGCATCCCGCCACCCGCGAGCAGTTGCTGAAGGTCAGCACCGCCACCCTGTGCACAGCCCTGTTCAAGCGCGGTCTGCG
CAACCAGTTCATCCAGGACCTGCGGCCGCTGAACCCCGGTCTGCCGAACATGGTGGGCCCGGCCTTCACGCTGCGCTACA
TGCCGGCGCGCGAGGACCTGAACCCGATCAGCGTCTTTCTCGAACGCAACCACCCGCAGCGCCAGGCGATCGAGCAATGC
CCCGCCGGCGCGGTGCTGGTGATCGACAGCCGCAAGGACGCGCGCGCCGCCTCGGCCGGCGCCATCCTGGTCACGCGGCT
GATGCAGCGCGGCGCCGCCGGGGTGGTGACCGACGGCGGTTTGCGCGACAGCCCCGACATCGCCCGGCTGGCCTTCCCGG
CCTACCACCAGCGCCCGAGCGCGCCAACCAATCTGACGCTGCACCAGGCCATAGACATCAACCGGCCCATAGGCTGCGGC
GATGCGCCGGTGTTTCCCGGCGACGTGATCGTCGGCGACGCGGAAGGCGTGGTCGTCCTTCCGGCCCATTGGGCCGACGA
ACTCGCCGCCGAAGCCACCGAGATGACGGTCTTCGAAGACTTCGTGCAAGAAATGGTGCTCCAGGGCCGTTCCATCCTCG
GCCTGTACCCGCCCACCGACGAAAAAAGCCGCGCCGACTTTGCCGCCTGGCGCCAGGCCAGGGGCCGCTGA

Upstream 100 bases:

>100_bases
CAGGCCAACGAAGGCTGCGACTTCGACTTCCTGGAAACCAGCTTCGGCAAGCCGGTGCCCGAGCCCGACATCTTCTGAAA
TCTTCTGAAGGAGACGCGCA

Downstream 100 bases:

>100_bases
GGCCCCGCGAGAGCCTGCCCAGGCCCGTTCCGGCCCGATCCATCTCGATCCATTTCGAGGAGACGACACCATCATGCGCT
GCATCCCGCTGTTGATAGCC

Product: hypothetical protein

Products: NA

Alternate protein names: HPS; D-arabino-3-hexulose-6-phosphate formaldehyde lyase [H]

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MHPATREQLLKVSTATLCTALFKRGLRNQFIQDLRPLNPGLPNMVGPAFTLRYMPAREDLNPISVFLERNHPQRQAIEQC
PAGAVLVIDSRKDARAASAGAILVTRLMQRGAAGVVTDGGLRDSPDIARLAFPAYHQRPSAPTNLTLHQAIDINRPIGCG
DAPVFPGDVIVGDAEGVVVLPAHWADELAAEATEMTVFEDFVQEMVLQGRSILGLYPPTDEKSRADFAAWRQARGR

Sequences:

>Translated_236_residues
MHPATREQLLKVSTATLCTALFKRGLRNQFIQDLRPLNPGLPNMVGPAFTLRYMPAREDLNPISVFLERNHPQRQAIEQC
PAGAVLVIDSRKDARAASAGAILVTRLMQRGAAGVVTDGGLRDSPDIARLAFPAYHQRPSAPTNLTLHQAIDINRPIGCG
DAPVFPGDVIVGDAEGVVVLPAHWADELAAEATEMTVFEDFVQEMVLQGRSILGLYPPTDEKSRADFAAWRQARGR
>Mature_236_residues
MHPATREQLLKVSTATLCTALFKRGLRNQFIQDLRPLNPGLPNMVGPAFTLRYMPAREDLNPISVFLERNHPQRQAIEQC
PAGAVLVIDSRKDARAASAGAILVTRLMQRGAAGVVTDGGLRDSPDIARLAFPAYHQRPSAPTNLTLHQAIDINRPIGCG
DAPVFPGDVIVGDAEGVVVLPAHWADELAAEATEMTVFEDFVQEMVLQGRSILGLYPPTDEKSRADFAAWRQARGR

Specific function: Catalyzes the condensation of ribulose 5-phosphate with formaldehyde to form 3-hexulose 6-phosphate [H]

COG id: COG0684

COG function: function code H; Demethylmenaquinone methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPS/KGPDC family. HPS subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR017120
- InterPro:   IPR001754
- InterPro:   IPR011060
- InterPro:   IPR005493 [H]

Pfam domain/function: PF03737 Methyltransf_6; PF00215 OMPdecase [H]

EC number: =4.1.2.43 [H]

Molecular weight: Translated: 25724; Mature: 25724

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPATREQLLKVSTATLCTALFKRGLRNQFIQDLRPLNPGLPNMVGPAFTLRYMPAREDL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEEEECCCCCCC
NPISVFLERNHPQRQAIEQCPAGAVLVIDSRKDARAASAGAILVTRLMQRGAAGVVTDGG
CCEEHEEECCCCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEECCC
LRDSPDIARLAFPAYHQRPSAPTNLTLHQAIDINRPIGCGDAPVFPGDVIVGDAEGVVVL
CCCCCCHHHHHCCHHHCCCCCCCCEEEEHEECCCCCCCCCCCCCCCCCEEEECCCCEEEE
PAHWADELAAEATEMTVFEDFVQEMVLQGRSILGLYPPTDEKSRADFAAWRQARGR
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MHPATREQLLKVSTATLCTALFKRGLRNQFIQDLRPLNPGLPNMVGPAFTLRYMPAREDL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEEEECCCCCCC
NPISVFLERNHPQRQAIEQCPAGAVLVIDSRKDARAASAGAILVTRLMQRGAAGVVTDGG
CCEEHEEECCCCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEECCC
LRDSPDIARLAFPAYHQRPSAPTNLTLHQAIDINRPIGCGDAPVFPGDVIVGDAEGVVVL
CCCCCCHHHHHCCHHHCCCCCCCCEEEEHEECCCCCCCCCCCCCCCCCEEEECCCCEEEE
PAHWADELAAEATEMTVFEDFVQEMVLQGRSILGLYPPTDEKSRADFAAWRQARGR
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA