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The map label for this gene is argK [C]

Identifier: 121610332

GI number: 121610332

Start: 3769703

End: 3770734

Strand: Direct

Name: argK [C]

Synonym: Veis_3400

Alternate gene names: 121610332

Gene position: 3769703-3770734 (Clockwise)

Preceding gene: 121610331

Following gene: 121610333

Centisome position: 67.72

GC content: 66.57

Gene sequence:

>1032_bases
ATGCGTGATGCGATATTGCATGGCGACGCATCCGTCCAGCGCCGCGCCATCGCCAAAGCCATTACCCTGCTGGAATCCAC
GCGGGCGCAGCATCGCGCGCAGGGCGATGCGCTGCTGACGGCGCTGTTGCCATACACCGGCAAGTCTTTGCGCCTGGGGT
TCAGCGGCGTGCCGGGGGTGGGCAAATCCACCTTGATCGAGGCGCTGGGGCTGTACCTGATCGACCAGGGCCGGCGCGTG
GCGGTGCTCACCATCGACCCGTCGAGTTCCGTATCGGGTGGCTCCATCCTGGGCGACAAGACGCGCATGGAAAAGCTGTC
CATGCACGAGCAGGCGTTTATCCGCCCCAGCCCGAGCAGCGGCACGCTGGGCGGCGTGGCCGAAAAGACCCGCGAGGCCA
TGCTGGTGTGCGAAGCGGCGGGCTACGACATCGTCATCGTCGAAACCGTGGGCGTGGGCCAAAGCGAGGTGGCGGTGGCG
GGCATGACGGACATGCTGGTGCTGATGCAGTTGCCCAACGCCGGCGATGACCTGCAGGCCATCAAGAAAGGCGTGCTGGA
ACTGGCCGATCTGGTGCTCATCAACAAGGCCGACATCGATGCCGATGCCGCCACACGGGCCCAAGCGCAGATCAGTTCCG
GCCTGCAGTTGACGGAAATACACGGACACGCCAGCGCGCACCCGCAGCCGCAGGCGGCGGCGGGCGCGCAACGCGCGGCG
CACTGGCAGCCCCGGGTCATCACATCGAGCGCATTGCATGGCCAGGGCATTGACACCTTGTGGGCGGCTGTGCGCGAATT
TCAAACGCTGCAAATGGCCAATGGCGCGTTCCACACGAGGCGCCAGAGCCAGGCGCTGGCGTGGATGTGGCAGCGCATCG
ACGCCGGGCTGAAGCAGTCTTTCAAAAACCACCCGGCCGTGCGCCAGCAACTGCCGCAACTCAGCGCCGCAGTGCAGTCC
GGGCAGATCGCGGCCAGCACGGCTGCGCGCCATCTGCTTGCGGCGGCCGTCGGCGAGGTCCCAACGGATTGA

Upstream 100 bases:

>100_bases
GATGACTCTCAAATCGAAACAGTGGTCAATGGTTTGATAGGGCGAGCATATGTGTCCGTGTCTGAAGACCAGGAAAAGCT
GCGCTACCCGGAGTCGCTGG

Downstream 100 bases:

>100_bases
GCCGAAAAGATCGAACCGCGGAGAAAGAAACCATGCACGACATCCTTGCGCAGCTCGAAATCAAGCGCGAACGCGCGCGC
CAGGGCGGTGGCGAGAAACG

Product: arginine/ornithine transport system ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MRDAILHGDASVQRRAIAKAITLLESTRAQHRAQGDALLTALLPYTGKSLRLGFSGVPGVGKSTLIEALGLYLIDQGRRV
AVLTIDPSSSVSGGSILGDKTRMEKLSMHEQAFIRPSPSSGTLGGVAEKTREAMLVCEAAGYDIVIVETVGVGQSEVAVA
GMTDMLVLMQLPNAGDDLQAIKKGVLELADLVLINKADIDADAATRAQAQISSGLQLTEIHGHASAHPQPQAAAGAQRAA
HWQPRVITSSALHGQGIDTLWAAVREFQTLQMANGAFHTRRQSQALAWMWQRIDAGLKQSFKNHPAVRQQLPQLSAAVQS
GQIAASTAARHLLAAAVGEVPTD

Sequences:

>Translated_343_residues
MRDAILHGDASVQRRAIAKAITLLESTRAQHRAQGDALLTALLPYTGKSLRLGFSGVPGVGKSTLIEALGLYLIDQGRRV
AVLTIDPSSSVSGGSILGDKTRMEKLSMHEQAFIRPSPSSGTLGGVAEKTREAMLVCEAAGYDIVIVETVGVGQSEVAVA
GMTDMLVLMQLPNAGDDLQAIKKGVLELADLVLINKADIDADAATRAQAQISSGLQLTEIHGHASAHPQPQAAAGAQRAA
HWQPRVITSSALHGQGIDTLWAAVREFQTLQMANGAFHTRRQSQALAWMWQRIDAGLKQSFKNHPAVRQQLPQLSAAVQS
GQIAASTAARHLLAAAVGEVPTD
>Mature_343_residues
MRDAILHGDASVQRRAIAKAITLLESTRAQHRAQGDALLTALLPYTGKSLRLGFSGVPGVGKSTLIEALGLYLIDQGRRV
AVLTIDPSSSVSGGSILGDKTRMEKLSMHEQAFIRPSPSSGTLGGVAEKTREAMLVCEAAGYDIVIVETVGVGQSEVAVA
GMTDMLVLMQLPNAGDDLQAIKKGVLELADLVLINKADIDADAATRAQAQISSGLQLTEIHGHASAHPQPQAAAGAQRAA
HWQPRVITSSALHGQGIDTLWAAVREFQTLQMANGAFHTRRQSQALAWMWQRIDAGLKQSFKNHPAVRQQLPQLSAAVQS
GQIAASTAARHLLAAAVGEVPTD

Specific function: May have GTPase activity. May also bind and hydrolyze ATP. May function as chaperone [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=344, Percent_Identity=44.4767441860465, Blast_Score=282, Evalue=4e-76,
Organism=Escherichia coli, GI1789285, Length=321, Percent_Identity=45.1713395638629, Blast_Score=271, Evalue=6e-74,
Organism=Caenorhabditis elegans, GI71994271, Length=358, Percent_Identity=38.8268156424581, Blast_Score=251, Evalue=3e-67,
Organism=Caenorhabditis elegans, GI71994275, Length=291, Percent_Identity=41.2371134020619, Blast_Score=233, Evalue=1e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129
- InterPro:   IPR003593 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 36225; Mature: 36225

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDAILHGDASVQRRAIAKAITLLESTRAQHRAQGDALLTALLPYTGKSLRLGFSGVPGV
CCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCC
GKSTLIEALGLYLIDQGRRVAVLTIDPSSSVSGGSILGDKTRMEKLSMHEQAFIRPSPSS
CHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCC
GTLGGVAEKTREAMLVCEAAGYDIVIVETVGVGQSEVAVAGMTDMLVLMQLPNAGDDLQA
CCCCHHHHHHHHHEEEEECCCCCEEEEEEECCCCCCEEHHHHHHHHHHHCCCCCCHHHHH
IKKGVLELADLVLINKADIDADAATRAQAQISSGLQLTEIHGHASAHPQPQAAAGAQRAA
HHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHH
HWQPRVITSSALHGQGIDTLWAAVREFQTLQMANGAFHTRRQSQALAWMWQRIDAGLKQS
CCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
FKNHPAVRQQLPQLSAAVQSGQIAASTAARHLLAAAVGEVPTD
HCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MRDAILHGDASVQRRAIAKAITLLESTRAQHRAQGDALLTALLPYTGKSLRLGFSGVPGV
CCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCC
GKSTLIEALGLYLIDQGRRVAVLTIDPSSSVSGGSILGDKTRMEKLSMHEQAFIRPSPSS
CHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCC
GTLGGVAEKTREAMLVCEAAGYDIVIVETVGVGQSEVAVAGMTDMLVLMQLPNAGDDLQA
CCCCHHHHHHHHHEEEEECCCCCEEEEEEECCCCCCEEHHHHHHHHHHHCCCCCCHHHHH
IKKGVLELADLVLINKADIDADAATRAQAQISSGLQLTEIHGHASAHPQPQAAAGAQRAA
HHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHH
HWQPRVITSSALHGQGIDTLWAAVREFQTLQMANGAFHTRRQSQALAWMWQRIDAGLKQS
CCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
FKNHPAVRQQLPQLSAAVQSGQIAASTAARHLLAAAVGEVPTD
HCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]