Click here to switch to the map view.

The map label for this gene is csd [H]

Identifier: 121610238

GI number: 121610238

Start: 3680626

End: 3681807

Strand: Direct

Name: csd [H]

Synonym: Veis_3297

Alternate gene names: 121610238

Gene position: 3680626-3681807 (Clockwise)

Preceding gene: 121610237

Following gene: 121610239

Centisome position: 66.12

GC content: 57.95

Gene sequence:

>1182_bases
ATGAATCTCGACACCATCAGAAACGATCTTTGCCTCGACCCCGGCATCGCCTACCTCGACAATGCGGCGGCCTCTGTCAT
GCCGCGCCAGGTGTTGCAGGCGGTGACCGGCTATCTGGAGCGCACCGCCACGACAGGCCCCTACCTGCCGTCGTTTCGGC
GCGAAACCTATGCCAGGCTGGAGGAAATTCGCGCTTCCACGGCTGCTTTCATCGCCGCCTCAAGCGAAGAAATTGCATTC
AACAAAAATGGTTCGGAAGGCATCAGCTTGGTCGCGCAGGGCCTGGACTGGCAGGAGGGTGATGAGGTCATCATCACCGA
CTTCGAAATGCTGAGCAACCTCACGCCATGGCTGCTGCTGCAACAGACCAGACGCATCCTGGTTCGCACCGTCGTTTCCA
ACGCGCAGGGCTTGCTTGAGCCTCTTGCCCTGGCCGCCCTGATGACACCTCGCACCCGATTGATCTCGGTCACGCATCTG
CCGAATGCGACTGGCGCGGTCCAGCCCATTGCAGCGGTGTGCAGGCTGGCGCAAGAACGCGGCATCATGAGCTTGATCAA
TGCCTCGCAAAGTTTCGGCCTGCTCCCCATCGATGTGCGTGCACTGGGTTGTGATTTTCTTGTGGCATGCGGTCGCAAGG
CACTGCGCGGCCCCGAAGGAACCGGAATTTTGTATGTCCGCGCAGCACTGATTCCCAGGCTTACCCCGGTATTGACAGGA
TGGTGGAACAGCAGTTTCGACCCGGAACGAAACAGCTTTACCTTGCCGCTCACAGGCAAACGTTTTGAAGCCGGCTGCCC
GATCATGCCGTCCATGATCGGCCTGGGCGCAGCAATCGACTATGCCAATCAGATGGGCATCGACCAGATTGCCTGCCGTG
TGGCGCGGCTGACTGCCTATACGATAGAGCGCTTGCTCAGCATTCCCGGGGCACAAATTTATGGCCCCGAGTCGGTGCAT
GATCGCATGTTGATCATCCCGTTCAACATCCATGGCGTTGATGCGGACAAGATAGTGCAGCATCTCGATGCGCATGGCGT
CATTATCGAGGCCGGACACTTCATGGCAACCCCCATCATGAAGCGTCACCAGATCAGCAAAATGGCGCGCATTTCGCCAC
ATTACTTCAATACCGAAGCAGAAATTGAGCGTGCCGTCGCCCTGATTCGAGAACTACTCTGA

Upstream 100 bases:

>100_bases
CAACACCATGGCGGCCGGGTTCATTGCGGGCGATGCGCTCTACAACTTCTTCAAGCCGATCTTCATCAGCAAATGATTCG
ACCCAGAGGACCTGCACAAT

Downstream 100 bases:

>100_bases
CCACGGATTTGCCTTAGCATTTTTACAGGAACAACTGCCATGCGACTGCTATTGCTTTCCAATTCGATCAACCCTGGCGG
CGCGTATTTGCAGCATGCGC

Product: class V aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MNLDTIRNDLCLDPGIAYLDNAAASVMPRQVLQAVTGYLERTATTGPYLPSFRRETYARLEEIRASTAAFIAASSEEIAF
NKNGSEGISLVAQGLDWQEGDEVIITDFEMLSNLTPWLLLQQTRRILVRTVVSNAQGLLEPLALAALMTPRTRLISVTHL
PNATGAVQPIAAVCRLAQERGIMSLINASQSFGLLPIDVRALGCDFLVACGRKALRGPEGTGILYVRAALIPRLTPVLTG
WWNSSFDPERNSFTLPLTGKRFEAGCPIMPSMIGLGAAIDYANQMGIDQIACRVARLTAYTIERLLSIPGAQIYGPESVH
DRMLIIPFNIHGVDADKIVQHLDAHGVIIEAGHFMATPIMKRHQISKMARISPHYFNTEAEIERAVALIRELL

Sequences:

>Translated_393_residues
MNLDTIRNDLCLDPGIAYLDNAAASVMPRQVLQAVTGYLERTATTGPYLPSFRRETYARLEEIRASTAAFIAASSEEIAF
NKNGSEGISLVAQGLDWQEGDEVIITDFEMLSNLTPWLLLQQTRRILVRTVVSNAQGLLEPLALAALMTPRTRLISVTHL
PNATGAVQPIAAVCRLAQERGIMSLINASQSFGLLPIDVRALGCDFLVACGRKALRGPEGTGILYVRAALIPRLTPVLTG
WWNSSFDPERNSFTLPLTGKRFEAGCPIMPSMIGLGAAIDYANQMGIDQIACRVARLTAYTIERLLSIPGAQIYGPESVH
DRMLIIPFNIHGVDADKIVQHLDAHGVIIEAGHFMATPIMKRHQISKMARISPHYFNTEAEIERAVALIRELL
>Mature_393_residues
MNLDTIRNDLCLDPGIAYLDNAAASVMPRQVLQAVTGYLERTATTGPYLPSFRRETYARLEEIRASTAAFIAASSEEIAF
NKNGSEGISLVAQGLDWQEGDEVIITDFEMLSNLTPWLLLQQTRRILVRTVVSNAQGLLEPLALAALMTPRTRLISVTHL
PNATGAVQPIAAVCRLAQERGIMSLINASQSFGLLPIDVRALGCDFLVACGRKALRGPEGTGILYVRAALIPRLTPVLTG
WWNSSFDPERNSFTLPLTGKRFEAGCPIMPSMIGLGAAIDYANQMGIDQIACRVARLTAYTIERLLSIPGAQIYGPESVH
DRMLIIPFNIHGVDADKIVQHLDAHGVIIEAGHFMATPIMKRHQISKMARISPHYFNTEAEIERAVALIRELL

Specific function: Cysteine Desulfurases Mobilize The Sulfur From L- Cysteine To Yield L-Alanine, An Essential Step In Sulfur Metabolism For Biosynthesis Of A Variety Of Sulfur-Containing Biomolecules. Component Of The Suf Operon, Which Is Activated And Required Under Speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=309, Percent_Identity=25.5663430420712, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1787970, Length=376, Percent_Identity=33.5106382978723, Blast_Score=204, Evalue=8e-54,
Organism=Escherichia coli, GI1789175, Length=390, Percent_Identity=28.7179487179487, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI48994898, Length=218, Percent_Identity=28.8990825688073, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI25143064, Length=301, Percent_Identity=25.5813953488372, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319831, Length=197, Percent_Identity=28.9340101522843, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI20129463, Length=278, Percent_Identity=27.6978417266187, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 43054; Mature: 43054

Theoretical pI: Translated: 6.71; Mature: 6.71

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLDTIRNDLCLDPGIAYLDNAAASVMPRQVLQAVTGYLERTATTGPYLPSFRRETYARL
CCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
EEIRASTAAFIAASSEEIAFNKNGSEGISLVAQGLDWQEGDEVIITDFEMLSNLTPWLLL
HHHHHHHHHHEEECCCCEEECCCCCHHHHHHHHCCCCCCCCCEEEECHHHHHCCCHHHHH
QQTRRILVRTVVSNAQGLLEPLALAALMTPRTRLISVTHLPNATGAVQPIAAVCRLAQER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEECCCCCCHHHHHHHHHHHHHHC
GIMSLINASQSFGLLPIDVRALGCDFLVACGRKALRGPEGTGILYVRAALIPRLTPVLTG
CHHHHHHCCCCCCCEEEHHHHHHHHHHHHCCHHHHCCCCCCCEEEEHHHHHHHHHHHHCC
WWNSSFDPERNSFTLPLTGKRFEAGCPIMPSMIGLGAAIDYANQMGIDQIACRVARLTAY
CCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
TIERLLSIPGAQIYGPESVHDRMLIIPFNIHGVDADKIVQHLDAHGVIIEAGHFMATPIM
HHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHCCCCEEEECCCHHHHHHH
KRHQISKMARISPHYFNTEAEIERAVALIRELL
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHC
>Mature Secondary Structure
MNLDTIRNDLCLDPGIAYLDNAAASVMPRQVLQAVTGYLERTATTGPYLPSFRRETYARL
CCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
EEIRASTAAFIAASSEEIAFNKNGSEGISLVAQGLDWQEGDEVIITDFEMLSNLTPWLLL
HHHHHHHHHHEEECCCCEEECCCCCHHHHHHHHCCCCCCCCCEEEECHHHHHCCCHHHHH
QQTRRILVRTVVSNAQGLLEPLALAALMTPRTRLISVTHLPNATGAVQPIAAVCRLAQER
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEECCCCCCHHHHHHHHHHHHHHC
GIMSLINASQSFGLLPIDVRALGCDFLVACGRKALRGPEGTGILYVRAALIPRLTPVLTG
CHHHHHHCCCCCCCEEEHHHHHHHHHHHHCCHHHHCCCCCCCEEEEHHHHHHHHHHHHCC
WWNSSFDPERNSFTLPLTGKRFEAGCPIMPSMIGLGAAIDYANQMGIDQIACRVARLTAY
CCCCCCCCCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
TIERLLSIPGAQIYGPESVHDRMLIIPFNIHGVDADKIVQHLDAHGVIIEAGHFMATPIM
HHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHCCCCEEEECCCHHHHHHH
KRHQISKMARISPHYFNTEAEIERAVALIRELL
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]