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The map label for this gene is fliD [H]

Identifier: 120613035

GI number: 120613035

Start: 4888396

End: 4889832

Strand: Reverse

Name: fliD [H]

Synonym: Aave_4399

Alternate gene names: 120613035

Gene position: 4889832-4888396 (Counterclockwise)

Preceding gene: 120613036

Following gene: 120613034

Centisome position: 91.35

GC content: 65.21

Gene sequence:

>1437_bases
ATGGCGAGCTTTTCTTCTTTGGGCATCGGCCTGGGTGGAGGCGTCAATGTCAATGACCTCATCAAGGCGTCCGTGGATGC
CGTCAAGCTGCCCATCACCCGGACCAACGGCCTGAGCCAGCAGGCGGCCGTGACCAATTCGAAGGTGTCCGCCTTCGGCC
AGCTCAAGTCGCTGGTGTCCACGCTATCCGATGCCGCCAACAAGCTGACCAGCGTCACCGGATGGAACGGTGTGGCGGCG
ACGTCGTCCAGCACCGATTTCGTGACCGTGTCGGCGGTGGGTGGTGCGGCGGCGACGTCTTTCAACGTGCAGGTGCAGAA
CCTGGCCAAGGCCCAGTCCTCCATTTCCGATTCGCTGACGCCTGCCAAGAGCGCCGTGGGCGCCGGCACGCTCACCCTCA
CCACGGGTACCTGGAGCGGCAGCCCCAAGAGTTTTGCCGCGGGCGCGGACGAGGGGGTGAAGATCGACGTCGCCGCGACC
GATACGCTGGAGGACGTCGCCAGCAAGATCAACGGCTCCAAGGCCGGCGTCACGGCCACGGTCCTGACCGATGCCTCGGG
CCAGCGCCTGATGCTGCGCAGCAAGACCACCGGCGAGAGCGCCGGCTACCAGCTCAGCGTCTCGGACGCGGACGGCAACA
ACAGCGACGCCGCCGGCCTGTCCCGCCTGCTGTCCGGCTCGACTGAATATGCGCAGAACGCCAACGCCACGGTCAACGGG
GTGGCCGTGACGTCGGGCACCAATGTCTTCGCCAATACCGTGGCGGGCGTGACGTTCACGGCCGTCAAGCCCACCACGAC
GGACGTGTCCATCACGGTCACCAAGGACAACTCGGCCGTCAAGGCCAACATCCAGGCCTTCGTCACGGCCTACAACGCTG
TCAACAGCGCGCTGAACGAGTCCACCAAATACGACAAGGACACGAAGACGGCCGGGCTGCTGCAGGGCGACTCGGGCGCC
GTGACGCTGCAGAACACGCTGCGGATGGCACTGCAGTCGGTCAACCAGTCCGGCGCGCTCCGCTCGCTGTCCGAAGTGGG
CGTGGTGTCGGCCGGCGGAAGCGGCAACCTGTCGCCCGACGGCAGCCTGACCCTTGACGCCACCAAGTTCGACAAGGCGA
TGCAGAACCCCGATGACGTGAAGGCGTTCTTCCGCGGCGCGGACGGCGGCAGCGTGACGGACGGCTTCGCCGGCAAGTTC
AAGGCCGTCACCTCGAGGCTGCTGGCGTCCGACGGCTTCTTCGCCGGCAAGGACCAGTCGTACAAGGAGATGCTCAAGCG
CAATGCCGCCGATATCGAGCGCATCAACGAACGGGCCAGCGAAGTGGAGAAGAACCTCACGGCACGCTACACGGCGCTGG
ACACCAAGATGTCCAACATGAACGCGCTCAACAGCTACATCCAGCAGCAGGTGGTGGCCTGGAATAAAACCCTGTGA

Upstream 100 bases:

>100_bases
TGGGTGGGTTATCCTGTGCTTATCAGCGAGATGCGACGCTGCCGGAACAGGATAATCTCCGTCGATACAACGCATCGCAT
CGACTGAATGGAGGTGGTAT

Downstream 100 bases:

>100_bases
AGGGGCTTCAGTTTTTTGGCGGGACGCCGATAAATTGAACAACAGATTCCGAGGAGCGACCGCCATGTTCACCGCTTACC
AATCCCGTGCCAATGCCTAT

Product: flagellar hook-associated 2 domain-containing protein

Products: NA

Alternate protein names: HAP2; Filament cap protein [H]

Number of amino acids: Translated: 478; Mature: 477

Protein sequence:

>478_residues
MASFSSLGIGLGGGVNVNDLIKASVDAVKLPITRTNGLSQQAAVTNSKVSAFGQLKSLVSTLSDAANKLTSVTGWNGVAA
TSSSTDFVTVSAVGGAAATSFNVQVQNLAKAQSSISDSLTPAKSAVGAGTLTLTTGTWSGSPKSFAAGADEGVKIDVAAT
DTLEDVASKINGSKAGVTATVLTDASGQRLMLRSKTTGESAGYQLSVSDADGNNSDAAGLSRLLSGSTEYAQNANATVNG
VAVTSGTNVFANTVAGVTFTAVKPTTTDVSITVTKDNSAVKANIQAFVTAYNAVNSALNESTKYDKDTKTAGLLQGDSGA
VTLQNTLRMALQSVNQSGALRSLSEVGVVSAGGSGNLSPDGSLTLDATKFDKAMQNPDDVKAFFRGADGGSVTDGFAGKF
KAVTSRLLASDGFFAGKDQSYKEMLKRNAADIERINERASEVEKNLTARYTALDTKMSNMNALNSYIQQQVVAWNKTL

Sequences:

>Translated_478_residues
MASFSSLGIGLGGGVNVNDLIKASVDAVKLPITRTNGLSQQAAVTNSKVSAFGQLKSLVSTLSDAANKLTSVTGWNGVAA
TSSSTDFVTVSAVGGAAATSFNVQVQNLAKAQSSISDSLTPAKSAVGAGTLTLTTGTWSGSPKSFAAGADEGVKIDVAAT
DTLEDVASKINGSKAGVTATVLTDASGQRLMLRSKTTGESAGYQLSVSDADGNNSDAAGLSRLLSGSTEYAQNANATVNG
VAVTSGTNVFANTVAGVTFTAVKPTTTDVSITVTKDNSAVKANIQAFVTAYNAVNSALNESTKYDKDTKTAGLLQGDSGA
VTLQNTLRMALQSVNQSGALRSLSEVGVVSAGGSGNLSPDGSLTLDATKFDKAMQNPDDVKAFFRGADGGSVTDGFAGKF
KAVTSRLLASDGFFAGKDQSYKEMLKRNAADIERINERASEVEKNLTARYTALDTKMSNMNALNSYIQQQVVAWNKTL
>Mature_477_residues
ASFSSLGIGLGGGVNVNDLIKASVDAVKLPITRTNGLSQQAAVTNSKVSAFGQLKSLVSTLSDAANKLTSVTGWNGVAAT
SSSTDFVTVSAVGGAAATSFNVQVQNLAKAQSSISDSLTPAKSAVGAGTLTLTTGTWSGSPKSFAAGADEGVKIDVAATD
TLEDVASKINGSKAGVTATVLTDASGQRLMLRSKTTGESAGYQLSVSDADGNNSDAAGLSRLLSGSTEYAQNANATVNGV
AVTSGTNVFANTVAGVTFTAVKPTTTDVSITVTKDNSAVKANIQAFVTAYNAVNSALNESTKYDKDTKTAGLLQGDSGAV
TLQNTLRMALQSVNQSGALRSLSEVGVVSAGGSGNLSPDGSLTLDATKFDKAMQNPDDVKAFFRGADGGSVTDGFAGKFK
AVTSRLLASDGFFAGKDQSYKEMLKRNAADIERINERASEVEKNLTARYTALDTKMSNMNALNSYIQQQVVAWNKTL

Specific function: Required for the morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the

COG id: COG1345

COG function: function code N; Flagellar capping protein

Gene ontology:

Cell location: Secreted. Bacterial flagellum [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliD family [H]

Homologues:

Organism=Escherichia coli, GI1788233, Length=489, Percent_Identity=28.6298568507157, Blast_Score=112, Evalue=4e-26,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010810
- InterPro:   IPR010809
- InterPro:   IPR003481 [H]

Pfam domain/function: PF07196 Flagellin_IN; PF07195 FliD_C; PF02465 FliD_N [H]

EC number: NA

Molecular weight: Translated: 48844; Mature: 48712

Theoretical pI: Translated: 8.67; Mature: 8.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASFSSLGIGLGGGVNVNDLIKASVDAVKLPITRTNGLSQQAAVTNSKVSAFGQLKSLVS
CCCCCCCCCCCCCCCCHHHHHHHCCCEEEEEEEECCCCCHHHHHCCHHHHHHHHHHHHHH
TLSDAANKLTSVTGWNGVAATSSSTDFVTVSAVGGAAATSFNVQVQNLAKAQSSISDSLT
HHHHHHHHHHCCCCCCCEEECCCCCCEEEEEECCCCEEEEEEEEHHHHHHHHHHHHHCCC
PAKSAVGAGTLTLTTGTWSGSPKSFAAGADEGVKIDVAATDTLEDVASKINGSKAGVTAT
CHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEECHHHHHHHHHCCCCCCCEEEE
VLTDASGQRLMLRSKTTGESAGYQLSVSDADGNNSDAAGLSRLLSGSTEYAQNANATVNG
EEECCCCCEEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCHHHHCCCCCEEEE
VAVTSGTNVFANTVAGVTFTAVKPTTTDVSITVTKDNSAVKANIQAFVTAYNAVNSALNE
EEEECCCCHHHHHHCCEEEEEECCCCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHH
STKYDKDTKTAGLLQGDSGAVTLQNTLRMALQSVNQSGALRSLSEVGVVSAGGSGNLSPD
CCCCCCCCCCCCEEECCCCCEEHHHHHHHHHHHCCCCCHHHHHHHCCEEECCCCCCCCCC
GSLTLDATKFDKAMQNPDDVKAFFRGADGGSVTDGFAGKFKAVTSRLLASDGFFAGKDQS
CCEEEEHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHH
YKEMLKRNAADIERINERASEVEKNLTARYTALDTKMSNMNALNSYIQQQVVAWNKTL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ASFSSLGIGLGGGVNVNDLIKASVDAVKLPITRTNGLSQQAAVTNSKVSAFGQLKSLVS
CCCCCCCCCCCCCCCHHHHHHHCCCEEEEEEEECCCCCHHHHHCCHHHHHHHHHHHHHH
TLSDAANKLTSVTGWNGVAATSSSTDFVTVSAVGGAAATSFNVQVQNLAKAQSSISDSLT
HHHHHHHHHHCCCCCCCEEECCCCCCEEEEEECCCCEEEEEEEEHHHHHHHHHHHHHCCC
PAKSAVGAGTLTLTTGTWSGSPKSFAAGADEGVKIDVAATDTLEDVASKINGSKAGVTAT
CHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCEEEEEEECHHHHHHHHHCCCCCCCEEEE
VLTDASGQRLMLRSKTTGESAGYQLSVSDADGNNSDAAGLSRLLSGSTEYAQNANATVNG
EEECCCCCEEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHCCCHHHHCCCCCEEEE
VAVTSGTNVFANTVAGVTFTAVKPTTTDVSITVTKDNSAVKANIQAFVTAYNAVNSALNE
EEEECCCCHHHHHHCCEEEEEECCCCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHHHHH
STKYDKDTKTAGLLQGDSGAVTLQNTLRMALQSVNQSGALRSLSEVGVVSAGGSGNLSPD
CCCCCCCCCCCCEEECCCCCEEHHHHHHHHHHHCCCCCHHHHHHHCCEEECCCCCCCCCC
GSLTLDATKFDKAMQNPDDVKAFFRGADGGSVTDGFAGKFKAVTSRLLASDGFFAGKDQS
CCEEEEHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHH
YKEMLKRNAADIERINERASEVEKNLTARYTALDTKMSNMNALNSYIQQQVVAWNKTL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10678962; 10984043 [H]