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The map label for this gene is cheA [H]

Identifier: 120613014

GI number: 120613014

Start: 4870549

End: 4872726

Strand: Reverse

Name: cheA [H]

Synonym: Aave_4378

Alternate gene names: 120613014

Gene position: 4872726-4870549 (Counterclockwise)

Preceding gene: 120613015

Following gene: 120613013

Centisome position: 91.03

GC content: 67.77

Gene sequence:

>2178_bases
ATGGCCGAAAACTACCAAGAAGGCGCGGGCGGCGATTTCGACCTCAGCCAGTTCTATCAGATCTTTTTCGAGGAAGCTGG
CGAGAACCTGGACCAGATGGAGCACATGCTGCTGGATCTGGACCTGAGCGCGGCCAACGACGAAGAGCTCAACGGCATCT
TCCGCTGCGCGCACTCCATCAAGGGGGGCGCCGCGACGTTCGGCTTCTCCGATGTCGCCGAACTCACTCACCAGATGGAG
TCCCTGCTGGACCGCCTGCGCAGGCACGAGCTGCAGCCCATCCCGCAGATGGTGGATGTCCTGCTCGAATCCGCGGACGC
GTCCCGCAGCCTGCTGGCCCGCCACCAGGCGGGCGGCCAGGGGGAAGCCCTGTCCACCGGTGACCTGGTGCGCCGCATCA
GCGAACTGGCTGCGGGCGTCGTGCCTGCAGCCGGTCCCGCCACGCCGCCGCCCCCGGCTCCGGCGCCCGCCCCGGCTCCC
GTGCAGGCCGCGCCGGCCCCGGCCCCCGTGGCCGCGCCTGCGTCGATGCCCGCATCGTCCGGCCCCGGTGTGGCCCGTTC
GCTGGAAATCCGCATCGGTCCCGTCGAGCGCAACGAGCAGGCGGATGCCATCAAGGACCTGTTCCGCGACATCGTCGGCC
TGGGCACGATCCGCGACCTGCCCTCCGACCAGCCGGGCGTGCGCGTTTTCGGCGTCCAAACCACCTCCACGGACGACGAC
CTGCTCGATCTGTTCGCATTCCATGTCTCGAAGGAGCAGGTGCGGATCACCGCAGCCGGCGCTTCCGAGGCTGAGCCTGC
CGAAGAGGCCGCCGGCGTGGCGGCCGCCCCGTCCGCTCCCGGCGGTTCGCTGGAGGTTTCCTACGGTTTCTTCCCGGGGG
CCCCCGGCATGCCGGGCGACCGTCCCGATGCCGCCGCCAGCACGCCCTCGGGTGCCGCCGAGGGCCCCGCATCCAGGCAG
GCGGCCTCCGGTGGCCGTGCCTCGGAAACCAAGGCCGTCAGCCAGGCGCAGATGGAATCCACCACCATCCGGGTGGCCGT
CAACAAGGTGGACCAGCTGATCAACCTGGTGGGTGAACTCGTCATCACCCAGGCCATGCTGGCGCAAAACAGCCGCGGCC
TCGATGGCGCGGTGTACCAGCAACTGCTCGCGGGGCTGGCGGACCTCGACCGCAACACCCGGGATCTGCAGGAATCGGTG
ATGTCCATCCGCATGATTCCGATGTCCATCGTGTTCAGCCGTTTCCCGCGCATGCTGCGCGACCTGGCCAACAAGCTGGG
CAAGAAGGTCGATCTCGTCACCCTGGGCGAAGCCACCGAACTCGACAAGAGCCTCGTCGAGAAGATCACCGACCCGCTGA
CCCACCTGGTGCGCAACAGCTGCGACCACGGCATCGAAATGCCGGCGGACCGCCTCGCGGCCGGCAAGTCCGAGCACGGC
ACCATCACGCTGTCCGCATCGCACCAGGGCGGCTCCATCGTCATCGAGGTGCGGGACGACGGACGCGGCCTGTCGCGCGA
AAAGATCCTGCGCAAGGCGCGCGAACGGGGCCTCGATGTTTCCGACCAGATGAGCGATGCGGACGTCTGGGGCCTCATCT
TCGCGCCCGGCTTCTCCACCGCCGACGAGGTCACCGACGTGTCCGGCCGCGGCGTGGGCATGGACGTGGTCAAGAAGAAC
ATCGCCGCGCTCAACGGTTCGGTCGAGATCGACTCCGCCGAAGGCTACGGCATGCGTGTCTCGGTGCGGCTGCCGCTCAC
CCTCGCCATCATGGACGGCATGTCCGTCGGCGTCGGCGAGGAGGTCTACATCCTGCCGCTGTCGTCCGTCGTGGAGTCCT
TCCAGGTCAACCCCGACGACGTCAACACCGTTGCTCAGGGCTCGCAACTGGTCAAGGTGCGCGACGAGTACATGCCCGTC
ATCGCCCTGGAGAGAACCTTCCAGGTGCCGCGCGTGGACAAGAGCAAGTCCAGCAACATCATGGTGGTCGTCGAGGCGGA
CGGCAGCCGTGTTGCGCTCCTGGTGGACGAACTGCTGGGGCAGCACCAGGTCGTGGTGAAAAACCTCGAGACCAATTACC
GGAAGGTGCCCAACGTGTCGGGCGCCACCATTCTGGGCGACGGCACCGTGGCACTGATCCTCGACACCGGGGCCCTGGTC
CGCCGTGTCCGCCATTGA

Upstream 100 bases:

>100_bases
CTGGCTGGTGAAACCCTTCGACCCCAACCGCCTGATCGAGGTCATCCAGAAAGTGATCCGCTGAGCCTCGGCGTCATACA
CAAGCACAAGGGAGCCATTC

Downstream 100 bases:

>100_bases
TACGCCGCTGGGCAGACTGAAGGAGAGCCACTCATGGCGACTGTGATGGAAAAAACGACCGAAGCGGCTGGCGCTTCCGT
GGGGGGTGCCCGCGAATACC

Product: CheA signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 725; Mature: 724

Protein sequence:

>725_residues
MAENYQEGAGGDFDLSQFYQIFFEEAGENLDQMEHMLLDLDLSAANDEELNGIFRCAHSIKGGAATFGFSDVAELTHQME
SLLDRLRRHELQPIPQMVDVLLESADASRSLLARHQAGGQGEALSTGDLVRRISELAAGVVPAAGPATPPPPAPAPAPAP
VQAAPAPAPVAAPASMPASSGPGVARSLEIRIGPVERNEQADAIKDLFRDIVGLGTIRDLPSDQPGVRVFGVQTTSTDDD
LLDLFAFHVSKEQVRITAAGASEAEPAEEAAGVAAAPSAPGGSLEVSYGFFPGAPGMPGDRPDAAASTPSGAAEGPASRQ
AASGGRASETKAVSQAQMESTTIRVAVNKVDQLINLVGELVITQAMLAQNSRGLDGAVYQQLLAGLADLDRNTRDLQESV
MSIRMIPMSIVFSRFPRMLRDLANKLGKKVDLVTLGEATELDKSLVEKITDPLTHLVRNSCDHGIEMPADRLAAGKSEHG
TITLSASHQGGSIVIEVRDDGRGLSREKILRKARERGLDVSDQMSDADVWGLIFAPGFSTADEVTDVSGRGVGMDVVKKN
IAALNGSVEIDSAEGYGMRVSVRLPLTLAIMDGMSVGVGEEVYILPLSSVVESFQVNPDDVNTVAQGSQLVKVRDEYMPV
IALERTFQVPRVDKSKSSNIMVVVEADGSRVALLVDELLGQHQVVVKNLETNYRKVPNVSGATILGDGTVALILDTGALV
RRVRH

Sequences:

>Translated_725_residues
MAENYQEGAGGDFDLSQFYQIFFEEAGENLDQMEHMLLDLDLSAANDEELNGIFRCAHSIKGGAATFGFSDVAELTHQME
SLLDRLRRHELQPIPQMVDVLLESADASRSLLARHQAGGQGEALSTGDLVRRISELAAGVVPAAGPATPPPPAPAPAPAP
VQAAPAPAPVAAPASMPASSGPGVARSLEIRIGPVERNEQADAIKDLFRDIVGLGTIRDLPSDQPGVRVFGVQTTSTDDD
LLDLFAFHVSKEQVRITAAGASEAEPAEEAAGVAAAPSAPGGSLEVSYGFFPGAPGMPGDRPDAAASTPSGAAEGPASRQ
AASGGRASETKAVSQAQMESTTIRVAVNKVDQLINLVGELVITQAMLAQNSRGLDGAVYQQLLAGLADLDRNTRDLQESV
MSIRMIPMSIVFSRFPRMLRDLANKLGKKVDLVTLGEATELDKSLVEKITDPLTHLVRNSCDHGIEMPADRLAAGKSEHG
TITLSASHQGGSIVIEVRDDGRGLSREKILRKARERGLDVSDQMSDADVWGLIFAPGFSTADEVTDVSGRGVGMDVVKKN
IAALNGSVEIDSAEGYGMRVSVRLPLTLAIMDGMSVGVGEEVYILPLSSVVESFQVNPDDVNTVAQGSQLVKVRDEYMPV
IALERTFQVPRVDKSKSSNIMVVVEADGSRVALLVDELLGQHQVVVKNLETNYRKVPNVSGATILGDGTVALILDTGALV
RRVRH
>Mature_724_residues
AENYQEGAGGDFDLSQFYQIFFEEAGENLDQMEHMLLDLDLSAANDEELNGIFRCAHSIKGGAATFGFSDVAELTHQMES
LLDRLRRHELQPIPQMVDVLLESADASRSLLARHQAGGQGEALSTGDLVRRISELAAGVVPAAGPATPPPPAPAPAPAPV
QAAPAPAPVAAPASMPASSGPGVARSLEIRIGPVERNEQADAIKDLFRDIVGLGTIRDLPSDQPGVRVFGVQTTSTDDDL
LDLFAFHVSKEQVRITAAGASEAEPAEEAAGVAAAPSAPGGSLEVSYGFFPGAPGMPGDRPDAAASTPSGAAEGPASRQA
ASGGRASETKAVSQAQMESTTIRVAVNKVDQLINLVGELVITQAMLAQNSRGLDGAVYQQLLAGLADLDRNTRDLQESVM
SIRMIPMSIVFSRFPRMLRDLANKLGKKVDLVTLGEATELDKSLVEKITDPLTHLVRNSCDHGIEMPADRLAAGKSEHGT
ITLSASHQGGSIVIEVRDDGRGLSREKILRKARERGLDVSDQMSDADVWGLIFAPGFSTADEVTDVSGRGVGMDVVKKNI
AALNGSVEIDSAEGYGMRVSVRLPLTLAIMDGMSVGVGEEVYILPLSSVVESFQVNPDDVNTVAQGSQLVKVRDEYMPVI
ALERTFQVPRVDKSKSSNIMVVVEADGSRVALLVDELLGQHQVVVKNLETNYRKVPNVSGATILGDGTVALILDTGALVR
RVRH

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=403, Percent_Identity=60.545905707196, Blast_Score=479, Evalue=1e-136,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 76697; Mature: 76565

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAENYQEGAGGDFDLSQFYQIFFEEAGENLDQMEHMLLDLDLSAANDEELNGIFRCAHSI
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHC
KGGAATFGFSDVAELTHQMESLLDRLRRHELQPIPQMVDVLLESADASRSLLARHQAGGQ
CCCCEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCC
GEALSTGDLVRRISELAAGVVPAAGPATPPPPAPAPAPAPVQAAPAPAPVAAPASMPASS
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GPGVARSLEIRIGPVERNEQADAIKDLFRDIVGLGTIRDLPSDQPGVRVFGVQTTSTDDD
CCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEEEEEECCCCHH
LLDLFAFHVSKEQVRITAAGASEAEPAEEAAGVAAAPSAPGGSLEVSYGFFPGAPGMPGD
HHHHHHHHCCCCEEEEEECCCCCCCCHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCC
RPDAAASTPSGAAEGPASRQAASGGRASETKAVSQAQMESTTIRVAVNKVDQLINLVGEL
CCCCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHH
VITQAMLAQNSRGLDGAVYQQLLAGLADLDRNTRDLQESVMSIRMIPMSIVFSRFPRMLR
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLANKLGKKVDLVTLGEATELDKSLVEKITDPLTHLVRNSCDHGIEMPADRLAAGKSEHG
HHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCC
TITLSASHQGGSIVIEVRDDGRGLSREKILRKARERGLDVSDQMSDADVWGLIFAPGFST
EEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCC
ADEVTDVSGRGVGMDVVKKNIAALNGSVEIDSAEGYGMRVSVRLPLTLAIMDGMSVGVGE
HHHHHCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCEEEEEECCEEEEEECCCCCCCCC
EVYILPLSSVVESFQVNPDDVNTVAQGSQLVKVRDEYMPVIALERTFQVPRVDKSKSSNI
EEEEEEHHHHHHHHCCCCCHHHHHHCCCCEEEEHHHCCCEEEEHHHCCCCCCCCCCCCCE
MVVVEADGSRVALLVDELLGQHQVVVKNLETNYRKVPNVSGATILGDGTVALILDTGALV
EEEEECCCCEEEHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEECCHHHH
RRVRH
HHHCC
>Mature Secondary Structure 
AENYQEGAGGDFDLSQFYQIFFEEAGENLDQMEHMLLDLDLSAANDEELNGIFRCAHSI
CCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHC
KGGAATFGFSDVAELTHQMESLLDRLRRHELQPIPQMVDVLLESADASRSLLARHQAGGQ
CCCCEECCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCC
GEALSTGDLVRRISELAAGVVPAAGPATPPPPAPAPAPAPVQAAPAPAPVAAPASMPASS
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GPGVARSLEIRIGPVERNEQADAIKDLFRDIVGLGTIRDLPSDQPGVRVFGVQTTSTDDD
CCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCEEEEEEEECCCCHH
LLDLFAFHVSKEQVRITAAGASEAEPAEEAAGVAAAPSAPGGSLEVSYGFFPGAPGMPGD
HHHHHHHHCCCCEEEEEECCCCCCCCHHHHCCCCCCCCCCCCCEEEEECCCCCCCCCCCC
RPDAAASTPSGAAEGPASRQAASGGRASETKAVSQAQMESTTIRVAVNKVDQLINLVGEL
CCCCCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHH
VITQAMLAQNSRGLDGAVYQQLLAGLADLDRNTRDLQESVMSIRMIPMSIVFSRFPRMLR
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLANKLGKKVDLVTLGEATELDKSLVEKITDPLTHLVRNSCDHGIEMPADRLAAGKSEHG
HHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCC
TITLSASHQGGSIVIEVRDDGRGLSREKILRKARERGLDVSDQMSDADVWGLIFAPGFST
EEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCC
ADEVTDVSGRGVGMDVVKKNIAALNGSVEIDSAEGYGMRVSVRLPLTLAIMDGMSVGVGE
HHHHHCCCCCCCCHHHHHHHHHHCCCCEEEECCCCCCEEEEEECCEEEEEECCCCCCCCC
EVYILPLSSVVESFQVNPDDVNTVAQGSQLVKVRDEYMPVIALERTFQVPRVDKSKSSNI
EEEEEEHHHHHHHHCCCCCHHHHHHCCCCEEEEHHHCCCEEEEHHHCCCCCCCCCCCCCE
MVVVEADGSRVALLVDELLGQHQVVVKNLETNYRKVPNVSGATILGDGTVALILDTGALV
EEEEECCCCEEEHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEECCHHHH
RRVRH
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3278311; 11677609 [H]