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The map label for this gene is cheW [H]

Identifier: 120613013

GI number: 120613013

Start: 4870015

End: 4870515

Strand: Reverse

Name: cheW [H]

Synonym: Aave_4377

Alternate gene names: 120613013

Gene position: 4870515-4870015 (Counterclockwise)

Preceding gene: 120613014

Following gene: 120613012

Centisome position: 90.99

GC content: 60.68

Gene sequence:

>501_bases
ATGGCGACTGTGATGGAAAAAACGACCGAAGCGGCTGGCGCTTCCGTGGGGGGTGCCCGCGAATACCTGACGTTCCGCCT
CGACCAGGAGGAATACGGCATCGACATCCTCAAGGTCCAGGAAATCCGGGGCTACGAGCCGCCGACCCGCATCGCGAATG
CGCCCGAATTCATCAAGGGCGTGACGAACCTGCGGGGCACCATCGTGCCCATCGTGGACATGCGGCTCAAGTTCGACTGC
TCCAAGGCCGAATACAACAGTTTCACGGTGGTCATCATCCTGAACCTGCGCAACCGGGTCGTGGGGATCGTGGTCGATTC
CGTGAGCGACGTCATGGAACTCACGTCCGACCAGATCCGGCTGGCCCCGGAAATCGAAAGCTCCATCGACAGCAACTGCA
TCGTGGGGCTCGGCTCCGTGGGCGAGCGCATGCTCATCCTTCTCGACATCGAGAAGCTCATGTCCAACCCGGACATGGGC
CTCATATCCACGCACGAATGA

Upstream 100 bases:

>100_bases
TCTGGGCGACGGCACCGTGGCACTGATCCTCGACACCGGGGCCCTGGTCCGCCGTGTCCGCCATTGATACGCCGCTGGGC
AGACTGAAGGAGAGCCACTC

Downstream 100 bases:

>100_bases
TCTGACGAAAGGGGGGCGAGGCAGACAGGCCCCTCCAAGTCAACGCGGAACAAGAGCGGCGTTTCCCGGTGCACCGGCCG
GTTGCCAGAGATGCGGAACT

Product: CheW protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MATVMEKTTEAAGASVGGAREYLTFRLDQEEYGIDILKVQEIRGYEPPTRIANAPEFIKGVTNLRGTIVPIVDMRLKFDC
SKAEYNSFTVVIILNLRNRVVGIVVDSVSDVMELTSDQIRLAPEIESSIDSNCIVGLGSVGERMLILLDIEKLMSNPDMG
LISTHE

Sequences:

>Translated_166_residues
MATVMEKTTEAAGASVGGAREYLTFRLDQEEYGIDILKVQEIRGYEPPTRIANAPEFIKGVTNLRGTIVPIVDMRLKFDC
SKAEYNSFTVVIILNLRNRVVGIVVDSVSDVMELTSDQIRLAPEIESSIDSNCIVGLGSVGERMLILLDIEKLMSNPDMG
LISTHE
>Mature_165_residues
ATVMEKTTEAAGASVGGAREYLTFRLDQEEYGIDILKVQEIRGYEPPTRIANAPEFIKGVTNLRGTIVPIVDMRLKFDCS
KAEYNSFTVVIILNLRNRVVGIVVDSVSDVMELTSDQIRLAPEIESSIDSNCIVGLGSVGERMLILLDIEKLMSNPDMGL
ISTHE

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=151, Percent_Identity=60.2649006622517, Blast_Score=184, Evalue=4e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 18293; Mature: 18162

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATVMEKTTEAAGASVGGAREYLTFRLDQEEYGIDILKVQEIRGYEPPTRIANAPEFIKG
CCCHHHHHHHHCCCCCCCCCEEEEEEECCHHHCEEEEEEEECCCCCCCHHCCCCHHHHHH
VTNLRGTIVPIVDMRLKFDCSKAEYNSFTVVIILNLRNRVVGIVVDSVSDVMELTSDQIR
HHHCCCEEEEEEEEEEEEECCCCCCCCEEEEEEEECCCCEEEEEEHHHHHHHHHCCCCEE
LAPEIESSIDSNCIVGLGSVGERMLILLDIEKLMSNPDMGLISTHE
ECCCHHHCCCCCEEEEECCCCCEEEEEEEHHHHHCCCCCCEEECCC
>Mature Secondary Structure 
ATVMEKTTEAAGASVGGAREYLTFRLDQEEYGIDILKVQEIRGYEPPTRIANAPEFIKG
CCHHHHHHHHCCCCCCCCCEEEEEEECCHHHCEEEEEEEECCCCCCCHHCCCCHHHHHH
VTNLRGTIVPIVDMRLKFDCSKAEYNSFTVVIILNLRNRVVGIVVDSVSDVMELTSDQIR
HHHCCCEEEEEEEEEEEEECCCCCCCCEEEEEEEECCCCEEEEEEHHHHHHHHHCCCCEE
LAPEIESSIDSNCIVGLGSVGERMLILLDIEKLMSNPDMGLISTHE
ECCCHHHCCCCCEEEEECCCCCEEEEEEEHHHHHCCCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]