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The map label for this gene is 120612963

Identifier: 120612963

GI number: 120612963

Start: 4805678

End: 4806598

Strand: Direct

Name: 120612963

Synonym: Aave_4327

Alternate gene names: NA

Gene position: 4805678-4806598 (Clockwise)

Preceding gene: 120612962

Following gene: 120612964

Centisome position: 89.78

GC content: 73.18

Gene sequence:

>921_bases
ATGGATGACAGGTCCACCGCCGGCCACGCGCCGGCCGCAGCCCCTGCCGCCGTGCCGGGCACCGAGCACGAATACCTCCT
CGAAGGCCACGGACCGCTGGCCTCGACCGGCGTGCTGCTGATCCACGGCCTGACCGGCACGCCCAACGAGATGCGGCTGC
TCGCCAAGGGCCTGCACCGCGCGGGCTTCACCGTGCTGGCCGTGCAGCTGGCCGGCCACTGCGGGACGCAGGACGACCTG
GTCGCCACGCGCTGGCAGGACTGGGCGGCCAGCGCCCGCCGCGGCGCCGAACGTCTCATGCAGCACACCGGCCGGCCGGT
CGTCGCCTGCGGCCTGTCGATGGGCGCGCTGCTGGCGCTGGCCCTGGCCATCGAGCGGCCGCGGCAGGTGGCCGGCGTGG
TGGCCCTGTCCACCACCTTCCGCTACGACGGCTGGAGCATGCCGGCCTATACGCGCCTGGCCTTTCTGCTGCCGCTTTTC
CGGGCCCTCGGCATCGGCCGCCGCAGCGTCTTCATGGAAGCACCGCCCTACGGCATCAAGGATGAAGCCCTGCGCGAGCG
CGTGGTGTCGCAGATGCATTCGGGCGACAGCGTGGCCGCCGGCCTGCCGGGCAACCCCTGGTGGTCGGTGATCGAGCTGC
GGGCACTCTCCGCCCGCGTGCGGCGCAACCTGGGCGCGGTGCGCGCGCCCTGCCTGGTGATGCACGCCCGCAACGACGAC
ATCGCCGCGGCAGGCAACGCCGAGGACATCGTGCGCGGCGTGCGCCACGCCCCGGTGGAGCTGGTGCTGCTGGACGACAG
CTACCACATGATCACCATCGACCGCGACCGCCGCACGGTGCTGGCGCGCACGGTGGCCTTCGCCGAATCGATCGCGCAGC
AGCAGGCGCAGGCGCAACCGCAGGAAGGCGCCACGCCATGA

Upstream 100 bases:

>100_bases
GCGACTTCTCGGACACGCTGGAGATGCTGCACCAGCTCGACGCGCTGGCGCCCCGCCAGCTGGAGGTGGCATGAACGCTG
CCGCCGCGACCCTGCGCGCC

Downstream 100 bases:

>100_bases
CGCCTCCGGACGGCGGCGGCATCACGCCGCTGGTGGCCCTGCTGTGGTTGCTGAACATGCTGGTGGACACGGGCGGACAG
CTCGCCTTCAAGGCCGCGGC

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: MGLP [H]

Number of amino acids: Translated: 306; Mature: 306

Protein sequence:

>306_residues
MDDRSTAGHAPAAAPAAVPGTEHEYLLEGHGPLASTGVLLIHGLTGTPNEMRLLAKGLHRAGFTVLAVQLAGHCGTQDDL
VATRWQDWAASARRGAERLMQHTGRPVVACGLSMGALLALALAIERPRQVAGVVALSTTFRYDGWSMPAYTRLAFLLPLF
RALGIGRRSVFMEAPPYGIKDEALRERVVSQMHSGDSVAAGLPGNPWWSVIELRALSARVRRNLGAVRAPCLVMHARNDD
IAAAGNAEDIVRGVRHAPVELVLLDDSYHMITIDRDRRTVLARTVAFAESIAQQQAQAQPQEGATP

Sequences:

>Translated_306_residues
MDDRSTAGHAPAAAPAAVPGTEHEYLLEGHGPLASTGVLLIHGLTGTPNEMRLLAKGLHRAGFTVLAVQLAGHCGTQDDL
VATRWQDWAASARRGAERLMQHTGRPVVACGLSMGALLALALAIERPRQVAGVVALSTTFRYDGWSMPAYTRLAFLLPLF
RALGIGRRSVFMEAPPYGIKDEALRERVVSQMHSGDSVAAGLPGNPWWSVIELRALSARVRRNLGAVRAPCLVMHARNDD
IAAAGNAEDIVRGVRHAPVELVLLDDSYHMITIDRDRRTVLARTVAFAESIAQQQAQAQPQEGATP
>Mature_306_residues
MDDRSTAGHAPAAAPAAVPGTEHEYLLEGHGPLASTGVLLIHGLTGTPNEMRLLAKGLHRAGFTVLAVQLAGHCGTQDDL
VATRWQDWAASARRGAERLMQHTGRPVVACGLSMGALLALALAIERPRQVAGVVALSTTFRYDGWSMPAYTRLAFLLPLF
RALGIGRRSVFMEAPPYGIKDEALRERVVSQMHSGDSVAAGLPGNPWWSVIELRALSARVRRNLGAVRAPCLVMHARNDD
IAAAGNAEDIVRGVRHAPVELVLLDDSYHMITIDRDRRTVLARTVAFAESIAQQQAQAQPQEGATP

Specific function: Hydrolyzes monoacylglycerols, with the highest activity occurring with 1-monolauroylglycerol [H]

COG id: COG1647

COG function: function code R; Esterase/lipase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipase/esterase LIP3/BchO family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014940
- InterPro:   IPR012354 [H]

Pfam domain/function: PF08840 BAAT_C [H]

EC number: =3.1.1.23 [H]

Molecular weight: Translated: 32873; Mature: 32873

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDRSTAGHAPAAAPAAVPGTEHEYLLEGHGPLASTGVLLIHGLTGTPNEMRLLAKGLHR
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHH
AGFTVLAVQLAGHCGTQDDLVATRWQDWAASARRGAERLMQHTGRPVVACGLSMGALLAL
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHH
ALAIERPRQVAGVVALSTTFRYDGWSMPAYTRLAFLLPLFRALGIGRRSVFMEAPPYGIK
HHHHHCCHHHHHEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCC
DEALRERVVSQMHSGDSVAAGLPGNPWWSVIELRALSARVRRNLGAVRAPCLVMHARNDD
HHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC
IAAAGNAEDIVRGVRHAPVELVLLDDSYHMITIDRDRRTVLARTVAFAESIAQQQAQAQP
CCCCCCHHHHHHHHHCCCEEEEEEECCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCC
QEGATP
CCCCCC
>Mature Secondary Structure
MDDRSTAGHAPAAAPAAVPGTEHEYLLEGHGPLASTGVLLIHGLTGTPNEMRLLAKGLHR
CCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCEEEEECCCCCCHHHHHHHHHHHH
AGFTVLAVQLAGHCGTQDDLVATRWQDWAASARRGAERLMQHTGRPVVACGLSMGALLAL
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHH
ALAIERPRQVAGVVALSTTFRYDGWSMPAYTRLAFLLPLFRALGIGRRSVFMEAPPYGIK
HHHHHCCHHHHHEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCC
DEALRERVVSQMHSGDSVAAGLPGNPWWSVIELRALSARVRRNLGAVRAPCLVMHARNDD
HHHHHHHHHHHHCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCC
IAAAGNAEDIVRGVRHAPVELVLLDDSYHMITIDRDRRTVLARTVAFAESIAQQQAQAQP
CCCCCCHHHHHHHHHCCCEEEEEEECCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCC
QEGATP
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11226879; 10731713 [H]