Click here to switch to the map view.

The map label for this gene is yciR [C]

Identifier: 120612928

GI number: 120612928

Start: 4763577

End: 4765895

Strand: Reverse

Name: yciR [C]

Synonym: Aave_4292

Alternate gene names: 120612928

Gene position: 4765895-4763577 (Counterclockwise)

Preceding gene: 120612929

Following gene: 120612927

Centisome position: 89.04

GC content: 71.11

Gene sequence:

>2319_bases
ATGTTCCGGCTCGCCGGGGTGTCGCTGCTGCTGCTCCTGATGGTGCAGGCGGCCGGGTTCATGGTGGTGCGCGCATCCAT
CGAGCGCAATGCCCGGGCGCAGATCGCCGTGGGGCTGGATGCGGACGAGCGGGTCTGGCGGCGCCTCATCGAACAGAACG
CGGAGCGGCTGCAGCAGGCCTCGGCGCTGCTGGCGGCCGATTACGGCTTCCGTTCGGCCGTCAACTCCGGCGATGCCGAG
ACCATCGCGTCGGTGCTGAGCAACCACGGCAGTCGCATCGGCGCGGCGGTCGCGGCCCTGCTGGATACGGAAATGCAGCT
GGTGGTGTCGTCCGCCTCGGACGCTTCCAGCGATTCCCGGTCCGTGCTGCTCGGCGTGCTGCCTCTGCTGGCGCAGCACC
CGGGCCGCCGCCAGATCGCGATCGTCGGCGGCGTGCCCTACCAGTTCGTGATGGTCCCCATGCGCGCGCCCCTGCCGGTC
GGCTGGGTGCTGATGGGGTTCCCGGTCGGGCAGGCGCTCGCCACCGAAATGCGCCAATTGCAGTCGATCGAGGTGGCCAT
CGTGGTGCGCGGCCCCGACGGCCAGCGGTCCGTGCCCGTGAGCACCCTGCCGGAAGACGACCGGCAGCGGCTCGTCGGGC
TGGCGGGGGCCGGCGACGTGGATACGGACGCCGGGCCGATGCTGGTCCGCCGGGTGTCCATCGAGAGCGCCAACGGCCAG
ACGGAGGTCCTCCTGATGCGTTCCCTGGAGGGCGTGCTCGCGCCCTACCGCCAGCTGCAGATGCTGCTCGGCGCCATCAC
GCTCGCGGGCGTGGCATTGTTCGCCATCGGTTTCGCGCTCATGGCGCGGCGCGTGGCCGCTCCCCTGCGCGCGGTGACGG
AGGCCACCCAGCGCATTTCGCGCGGCAATTACGCCGAGCCCATCGAGCACACGCACCGCAAGGACGAGATCGGCCGCCTC
GCGCGCTCCTTCGATCGCATGCGGCTGGGCATCGCGGCGCAGCAGGACGAGATCCGCCAGCTCGCCGACACCGACCGGCT
CACCGGCGTGCCGAACCGGGAGCGGTTCCGCCGCATGCTGATGGAGGCCATGGAGCACGGGGGGCGCTCCGGGGAACCGC
TGTCGGTGATCGCACTGGACCTCGACCGCTTCAAGCAGGTCAACGACGTGCTGGGTTATGCGCTGGGCGACCGGCTGCTG
CAGGCGGTGGTGGCGCGCATCGCGTCCCACCTGCGCGCGCAGCGGGAGGTCGTGGCGCGGCTCGGGGGCAACGAGTTCGC
CGTGCTGCTGCCCGGTGCGGACGAGGCGTCCGCCCGCGACACGGCGCAGCGCATCACCCGGGCGTTCGAGTCGCCCCTGG
TGTTCGACGACCAGATGGTGGACCTGAGCGCGGGCATCGGCATCGCCTGCTGGCCGGGGCCCGCGCATGACGCCGACACC
CTGCTCGGCCATGCGGAAATCGCGATGTATGCGGCCAAGCGGCGCCTGCATGGCGCGCAGATCTACGACCCGTCGATGGA
GTCCTCCAGCGCCGAGGCGCTGTCGCTGCTGTCCGAGCTGCGCCGTGCGGTGGAAGCCGGCGAACTGCGGCTTTTCCTGC
AGCCCAAGCTCCGGCTGGACGGCCAGGGCGGCAGCGGGGCCGAGGCGCTCGTGCGCTGGCAACATCCGGTGCGCGGCCTC
GTGCCGCCCATGCAGTTCATCCCCTTCGCCGAGCAGACCGGCTTCGTGCGGCAGCTCACGCTCTGGATCTTCGAGCAGGC
CGCCCGCTACCTCGCACGGCCGCAGGTGCAGGGCCTGGGTCTGCGCATCTCGGTGAACCTGTCCACGCGCGACCTCATGG
ACACGGACCTGAGCACCCGCCTGGGCACGCTCATGGCGCGGCACGGCGTGGAGCCGGGGAGTTTCTGCCTGGAGATCACC
GAAAGCGCCATCATGGACGACCCCGGCCGGGCCGAGGCCATGCTGAACCGGCTGTCCGCGCAGGGCTTCAAGCTGTCCAT
CGACGACTTCGGCACCGGCTACTCCTCGCTGGCCTACCTCAAGCGCCTGCCGGTGGACGAACTGAAGATCGACAAGTCCT
TCGTCATGGGCATGGCGGCGGACGCGGGCGATGCGCAGATCGTGCGCTCCACCATCGACCTGGCGCACAACCTGGGGCTC
TCCGTCGTGGCCGAGGGCGTGGAATCCGCCGCGATCCTGGAGCAGCTGCGCGGGCTGCGCTGCGACGAAGCCCAGGGCTA
CCACATCGGCCGGCCGATGCCCGCGGACGACTTCCTCGCCTGGCACGAGGCCGCCGCCGCTGCCGCCGCGCGAAAATAG

Upstream 100 bases:

>100_bases
TGGCCCAGCCGCTCGCCGTCGCCGAACCGGGCGGGGCGCCGGTGACCGCGCGGCTGCCAGGGGCCGTGCAGTGAGCTGGC
GCGCGTTCGGCCAGAGCCTG

Downstream 100 bases:

>100_bases
CGCCATGTCCGATTCCGCTCCCCGCCGCCGCCTGTCGCTCCCGCCCAGCGGCCCGCGCGCCAGCCAGCCCGATCCCGCGC
CGCCCCGGCCGCCCCGGCCG

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 772; Mature: 772

Protein sequence:

>772_residues
MFRLAGVSLLLLLMVQAAGFMVVRASIERNARAQIAVGLDADERVWRRLIEQNAERLQQASALLAADYGFRSAVNSGDAE
TIASVLSNHGSRIGAAVAALLDTEMQLVVSSASDASSDSRSVLLGVLPLLAQHPGRRQIAIVGGVPYQFVMVPMRAPLPV
GWVLMGFPVGQALATEMRQLQSIEVAIVVRGPDGQRSVPVSTLPEDDRQRLVGLAGAGDVDTDAGPMLVRRVSIESANGQ
TEVLLMRSLEGVLAPYRQLQMLLGAITLAGVALFAIGFALMARRVAAPLRAVTEATQRISRGNYAEPIEHTHRKDEIGRL
ARSFDRMRLGIAAQQDEIRQLADTDRLTGVPNRERFRRMLMEAMEHGGRSGEPLSVIALDLDRFKQVNDVLGYALGDRLL
QAVVARIASHLRAQREVVARLGGNEFAVLLPGADEASARDTAQRITRAFESPLVFDDQMVDLSAGIGIACWPGPAHDADT
LLGHAEIAMYAAKRRLHGAQIYDPSMESSSAEALSLLSELRRAVEAGELRLFLQPKLRLDGQGGSGAEALVRWQHPVRGL
VPPMQFIPFAEQTGFVRQLTLWIFEQAARYLARPQVQGLGLRISVNLSTRDLMDTDLSTRLGTLMARHGVEPGSFCLEIT
ESAIMDDPGRAEAMLNRLSAQGFKLSIDDFGTGYSSLAYLKRLPVDELKIDKSFVMGMAADAGDAQIVRSTIDLAHNLGL
SVVAEGVESAAILEQLRGLRCDEAQGYHIGRPMPADDFLAWHEAAAAAAARK

Sequences:

>Translated_772_residues
MFRLAGVSLLLLLMVQAAGFMVVRASIERNARAQIAVGLDADERVWRRLIEQNAERLQQASALLAADYGFRSAVNSGDAE
TIASVLSNHGSRIGAAVAALLDTEMQLVVSSASDASSDSRSVLLGVLPLLAQHPGRRQIAIVGGVPYQFVMVPMRAPLPV
GWVLMGFPVGQALATEMRQLQSIEVAIVVRGPDGQRSVPVSTLPEDDRQRLVGLAGAGDVDTDAGPMLVRRVSIESANGQ
TEVLLMRSLEGVLAPYRQLQMLLGAITLAGVALFAIGFALMARRVAAPLRAVTEATQRISRGNYAEPIEHTHRKDEIGRL
ARSFDRMRLGIAAQQDEIRQLADTDRLTGVPNRERFRRMLMEAMEHGGRSGEPLSVIALDLDRFKQVNDVLGYALGDRLL
QAVVARIASHLRAQREVVARLGGNEFAVLLPGADEASARDTAQRITRAFESPLVFDDQMVDLSAGIGIACWPGPAHDADT
LLGHAEIAMYAAKRRLHGAQIYDPSMESSSAEALSLLSELRRAVEAGELRLFLQPKLRLDGQGGSGAEALVRWQHPVRGL
VPPMQFIPFAEQTGFVRQLTLWIFEQAARYLARPQVQGLGLRISVNLSTRDLMDTDLSTRLGTLMARHGVEPGSFCLEIT
ESAIMDDPGRAEAMLNRLSAQGFKLSIDDFGTGYSSLAYLKRLPVDELKIDKSFVMGMAADAGDAQIVRSTIDLAHNLGL
SVVAEGVESAAILEQLRGLRCDEAQGYHIGRPMPADDFLAWHEAAAAAAARK
>Mature_772_residues
MFRLAGVSLLLLLMVQAAGFMVVRASIERNARAQIAVGLDADERVWRRLIEQNAERLQQASALLAADYGFRSAVNSGDAE
TIASVLSNHGSRIGAAVAALLDTEMQLVVSSASDASSDSRSVLLGVLPLLAQHPGRRQIAIVGGVPYQFVMVPMRAPLPV
GWVLMGFPVGQALATEMRQLQSIEVAIVVRGPDGQRSVPVSTLPEDDRQRLVGLAGAGDVDTDAGPMLVRRVSIESANGQ
TEVLLMRSLEGVLAPYRQLQMLLGAITLAGVALFAIGFALMARRVAAPLRAVTEATQRISRGNYAEPIEHTHRKDEIGRL
ARSFDRMRLGIAAQQDEIRQLADTDRLTGVPNRERFRRMLMEAMEHGGRSGEPLSVIALDLDRFKQVNDVLGYALGDRLL
QAVVARIASHLRAQREVVARLGGNEFAVLLPGADEASARDTAQRITRAFESPLVFDDQMVDLSAGIGIACWPGPAHDADT
LLGHAEIAMYAAKRRLHGAQIYDPSMESSSAEALSLLSELRRAVEAGELRLFLQPKLRLDGQGGSGAEALVRWQHPVRGL
VPPMQFIPFAEQTGFVRQLTLWIFEQAARYLARPQVQGLGLRISVNLSTRDLMDTDLSTRLGTLMARHGVEPGSFCLEIT
ESAIMDDPGRAEAMLNRLSAQGFKLSIDDFGTGYSSLAYLKRLPVDELKIDKSFVMGMAADAGDAQIVRSTIDLAHNLGL
SVVAEGVESAAILEQLRGLRCDEAQGYHIGRPMPADDFLAWHEAAAAAAARK

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=430, Percent_Identity=36.5116279069767, Blast_Score=267, Evalue=2e-72,
Organism=Escherichia coli, GI87081921, Length=426, Percent_Identity=33.0985915492958, Blast_Score=223, Evalue=3e-59,
Organism=Escherichia coli, GI226510982, Length=551, Percent_Identity=27.4047186932849, Blast_Score=187, Evalue=2e-48,
Organism=Escherichia coli, GI1787055, Length=407, Percent_Identity=28.2555282555283, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1790496, Length=254, Percent_Identity=35.4330708661417, Blast_Score=153, Evalue=5e-38,
Organism=Escherichia coli, GI87082096, Length=503, Percent_Identity=28.0318091451292, Blast_Score=142, Evalue=6e-35,
Organism=Escherichia coli, GI1786507, Length=256, Percent_Identity=33.59375, Blast_Score=140, Evalue=4e-34,
Organism=Escherichia coli, GI1788502, Length=251, Percent_Identity=34.2629482071713, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI87081845, Length=243, Percent_Identity=34.5679012345679, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI87081743, Length=248, Percent_Identity=35.8870967741936, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1788849, Length=360, Percent_Identity=30.2777777777778, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI87081980, Length=268, Percent_Identity=32.4626865671642, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1788381, Length=436, Percent_Identity=26.605504587156, Blast_Score=102, Evalue=1e-22,
Organism=Escherichia coli, GI145693134, Length=153, Percent_Identity=35.2941176470588, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1787816, Length=158, Percent_Identity=32.9113924050633, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87082007, Length=178, Percent_Identity=33.7078651685393, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1786584, Length=164, Percent_Identity=26.8292682926829, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787802, Length=177, Percent_Identity=29.3785310734463, Blast_Score=74, Evalue=5e-14,
Organism=Escherichia coli, GI1787262, Length=107, Percent_Identity=35.5140186915888, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI87081977, Length=155, Percent_Identity=33.5483870967742, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1788956, Length=243, Percent_Identity=27.9835390946502, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1789650, Length=425, Percent_Identity=21.4117647058824, Blast_Score=63, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 83602; Mature: 83602

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS50885 HAMP ; PS00445 FGGY_KINASES_2 ; PS50883 EAL ; PS50887 GGDEF ; PS00284 SERPIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRLAGVSLLLLLMVQAAGFMVVRASIERNARAQIAVGLDADERVWRRLIEQNAERLQQA
CCCHHHHHHHHHHHHHHCCCEEEEEHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHH
SALLAADYGFRSAVNSGDAETIASVLSNHGSRIGAAVAALLDTEMQLVVSSASDASSDSR
HHHHHHCCCHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCHH
SVLLGVLPLLAQHPGRRQIAIVGGVPYQFVMVPMRAPLPVGWVLMGFPVGQALATEMRQL
HHHHHHHHHHHCCCCCCEEEEECCCCEEEEEEECCCCCCCCHHEECCCCHHHHHHHHHHH
QSIEVAIVVRGPDGQRSVPVSTLPEDDRQRLVGLAGAGDVDTDAGPMLVRRVSIESANGQ
HCCEEEEEEECCCCCCCCCCCCCCCHHHHHHEEECCCCCCCCCCCCCEEEEEEEECCCCC
TEVLLMRSLEGVLAPYRQLQMLLGAITLAGVALFAIGFALMARRVAAPLRAVTEATQRIS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGNYAEPIEHTHRKDEIGRLARSFDRMRLGIAAQQDEIRQLADTDRLTGVPNRERFRRML
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
MEAMEHGGRSGEPLSVIALDLDRFKQVNDVLGYALGDRLLQAVVARIASHLRAQREVVAR
HHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGGNEFAVLLPGADEASARDTAQRITRAFESPLVFDDQMVDLSAGIGIACWPGPAHDADT
CCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCEEEECCCCCCCHHH
LLGHAEIAMYAAKRRLHGAQIYDPSMESSSAEALSLLSELRRAVEAGELRLFLQPKLRLD
HHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCEEEC
GQGGSGAEALVRWQHPVRGLVPPMQFIPFAEQTGFVRQLTLWIFEQAARYLARPQVQGLG
CCCCCCHHHHHHHHCCHHCCCCCHHHCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCE
LRISVNLSTRDLMDTDLSTRLGTLMARHGVEPGSFCLEITESAIMDDPGRAEAMLNRLSA
EEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHC
QGFKLSIDDFGTGYSSLAYLKRLPVDELKIDKSFVMGMAADAGDAQIVRSTIDLAHNLGL
CCCEEECCCCCCCHHHHHHHHHCCHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCH
SVVAEGVESAAILEQLRGLRCDEAQGYHIGRPMPADDFLAWHEAAAAAAARK
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFRLAGVSLLLLLMVQAAGFMVVRASIERNARAQIAVGLDADERVWRRLIEQNAERLQQA
CCCHHHHHHHHHHHHHHCCCEEEEEHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHH
SALLAADYGFRSAVNSGDAETIASVLSNHGSRIGAAVAALLDTEMQLVVSSASDASSDSR
HHHHHHCCCHHHHCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCCCCCCCHH
SVLLGVLPLLAQHPGRRQIAIVGGVPYQFVMVPMRAPLPVGWVLMGFPVGQALATEMRQL
HHHHHHHHHHHCCCCCCEEEEECCCCEEEEEEECCCCCCCCHHEECCCCHHHHHHHHHHH
QSIEVAIVVRGPDGQRSVPVSTLPEDDRQRLVGLAGAGDVDTDAGPMLVRRVSIESANGQ
HCCEEEEEEECCCCCCCCCCCCCCCHHHHHHEEECCCCCCCCCCCCCEEEEEEEECCCCC
TEVLLMRSLEGVLAPYRQLQMLLGAITLAGVALFAIGFALMARRVAAPLRAVTEATQRIS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGNYAEPIEHTHRKDEIGRLARSFDRMRLGIAAQQDEIRQLADTDRLTGVPNRERFRRML
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHH
MEAMEHGGRSGEPLSVIALDLDRFKQVNDVLGYALGDRLLQAVVARIASHLRAQREVVAR
HHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGGNEFAVLLPGADEASARDTAQRITRAFESPLVFDDQMVDLSAGIGIACWPGPAHDADT
CCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCEEEECCCCCCCHHH
LLGHAEIAMYAAKRRLHGAQIYDPSMESSSAEALSLLSELRRAVEAGELRLFLQPKLRLD
HHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCEEEEECCCEEEC
GQGGSGAEALVRWQHPVRGLVPPMQFIPFAEQTGFVRQLTLWIFEQAARYLARPQVQGLG
CCCCCCHHHHHHHHCCHHCCCCCHHHCCCHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCE
LRISVNLSTRDLMDTDLSTRLGTLMARHGVEPGSFCLEITESAIMDDPGRAEAMLNRLSA
EEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHC
QGFKLSIDDFGTGYSSLAYLKRLPVDELKIDKSFVMGMAADAGDAQIVRSTIDLAHNLGL
CCCEEECCCCCCCHHHHHHHHHCCHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHCCH
SVVAEGVESAAILEQLRGLRCDEAQGYHIGRPMPADDFLAWHEAAAAAAARK
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]