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The map label for this gene is rhbA [H]

Identifier: 120612856

GI number: 120612856

Start: 4676758

End: 4678167

Strand: Direct

Name: rhbA [H]

Synonym: Aave_4220

Alternate gene names: 120612856

Gene position: 4676758-4678167 (Clockwise)

Preceding gene: 120612855

Following gene: 120612857

Centisome position: 87.37

GC content: 63.26

Gene sequence:

>1410_bases
ATGAACAAACCTCTCTATTTCACCCTCCCGGCACCGCAGGACATCGGCGGTCCCCTTGAACCCACTCCTCAGCGCCGGTT
CCAGCAGGGAGTGGAACTGAGGAACCAGGAGCGTCTGGAATCGGAGGTGCGGTCCTACCCGCGGCGCTTTCCCATGGCAA
TCCGCAGGGCCCAGGGAGCCATCGTTGAAGACACGCTGGGCCAGCGCTATCTGGATTGCCTGGCCGGAGCCGGAGCACTG
GCACTCGGGCACAACCACCCCGAGGTGACAGGAGCGGTGGTGGCGGCGATCCAGTCGGGCATTCCCCAGCAGGCACTTGA
CGTGGCGACACCTTCCAAGGACGCGCTCATACAGGAAATTATGGGATTTCTTCCTGCCAGCTTCGCCCAGGACTCCTGCA
TTCAGTTCTGCGGTCCGTCGGGATCGGACGCCGTGGAGGCTGCCATCAAACTGGCGAAGCAATGCACGGGACGCCACAAC
ATCGCCGCGTTCCATGGCGCCTACCATGGCATGACGAACGGTGCGCAGGCCCTGATGGGCAACCTGGGTGCGAAGCAGCG
GCGCACCGGGCTGATGCCCGATGTGCATTTCTTCCCATTTCCCTACGGCCTGCGCTGCAAGTTCGGCCTCGGCGGAGAGG
CCGGTGAACGGGCATCGATCAGGTACATCGAATCCGTGCTGCACGACCAGGAAAGCGGTATGGTCAAGCCCGCCGCCATG
ATTCTGGAACCCATTCAGGGCGAAGGAGGGGTTCTACCGGCCTCGGACTATTGGTTGCGGGAGATCCGACGCATCACATC
CGAACTGGGTATCGTCCTCGTCTTCGACGAAATCCAGTGCGGAGTAGCTCGCTCCGGACGCCACTTCGCTTTCGAACACG
CAGGCGTGGAACCGGACATCCTCGTGCTGTCGAAGGCTGTCGGGGGCGGGCTCCCCCTTTCGTGCCTGGTGTTCAAGAAG
CGGTTCGACAACTGGACCCCGGGGGAGCACGCGGGCACCTTCCGGGGCACCCAGTGGGCCATGGTTGCCGGCACCAGAAC
ATTGCAGATCATCCAGCGCGATGGCTTGGCCCTGAATGCGGACCGCATGGGAGCCAGCTTGAGCGGCAGGCTGGCAGCGC
TACGGCAGGACCATCCATGTATTGCGGAAATCCGCGGCAAGGGTTTGATGCTGGGCATTGAAATCGTTGACCCGAAACGC
GTGGATGCGCTGGGTCAACCGCTTGCCGACGGGCAGCGCGCGGCCCGGATTCAGGCCGCGGCCTTGCGGCATGGCCTGAT
GATAGAGAAGGGTGGACGGCATGGCGCGGTCTTGCGCTTTCTCCCCCCCTTGAACATCACGGATGATCAGATCGATTTCG
CGGCCCGGGCCTTCACACACGCCATGCAGGCCACGGAGCAGGCACGGTGA

Upstream 100 bases:

>100_bases
ACCCCACATCCCGCAAGACCGCCTTCCAGACCTTCGGCATCGAAGATCGCTGGAAGGACGAAGCATCCAGCCGGCAGCCC
ACCATGGCAGGCACAGCATC

Downstream 100 bases:

>100_bases
CGGAATCGTGGAAAGAGCACTTCATCCGGACGGGCTGCGGAGGTGCTGATCGTTATCGTGCCGTGATGGAGTCCTGCGTG
GAGGAACTGTCGAGTCTTTT

Product: aminotransferase

Products: NA

Alternate protein names: Diaminobutyrate transaminase; L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase; DABA aminotransferase; DABA-AT; L-diaminobutyric acid transaminase [H]

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MNKPLYFTLPAPQDIGGPLEPTPQRRFQQGVELRNQERLESEVRSYPRRFPMAIRRAQGAIVEDTLGQRYLDCLAGAGAL
ALGHNHPEVTGAVVAAIQSGIPQQALDVATPSKDALIQEIMGFLPASFAQDSCIQFCGPSGSDAVEAAIKLAKQCTGRHN
IAAFHGAYHGMTNGAQALMGNLGAKQRRTGLMPDVHFFPFPYGLRCKFGLGGEAGERASIRYIESVLHDQESGMVKPAAM
ILEPIQGEGGVLPASDYWLREIRRITSELGIVLVFDEIQCGVARSGRHFAFEHAGVEPDILVLSKAVGGGLPLSCLVFKK
RFDNWTPGEHAGTFRGTQWAMVAGTRTLQIIQRDGLALNADRMGASLSGRLAALRQDHPCIAEIRGKGLMLGIEIVDPKR
VDALGQPLADGQRAARIQAAALRHGLMIEKGGRHGAVLRFLPPLNITDDQIDFAARAFTHAMQATEQAR

Sequences:

>Translated_469_residues
MNKPLYFTLPAPQDIGGPLEPTPQRRFQQGVELRNQERLESEVRSYPRRFPMAIRRAQGAIVEDTLGQRYLDCLAGAGAL
ALGHNHPEVTGAVVAAIQSGIPQQALDVATPSKDALIQEIMGFLPASFAQDSCIQFCGPSGSDAVEAAIKLAKQCTGRHN
IAAFHGAYHGMTNGAQALMGNLGAKQRRTGLMPDVHFFPFPYGLRCKFGLGGEAGERASIRYIESVLHDQESGMVKPAAM
ILEPIQGEGGVLPASDYWLREIRRITSELGIVLVFDEIQCGVARSGRHFAFEHAGVEPDILVLSKAVGGGLPLSCLVFKK
RFDNWTPGEHAGTFRGTQWAMVAGTRTLQIIQRDGLALNADRMGASLSGRLAALRQDHPCIAEIRGKGLMLGIEIVDPKR
VDALGQPLADGQRAARIQAAALRHGLMIEKGGRHGAVLRFLPPLNITDDQIDFAARAFTHAMQATEQAR
>Mature_469_residues
MNKPLYFTLPAPQDIGGPLEPTPQRRFQQGVELRNQERLESEVRSYPRRFPMAIRRAQGAIVEDTLGQRYLDCLAGAGAL
ALGHNHPEVTGAVVAAIQSGIPQQALDVATPSKDALIQEIMGFLPASFAQDSCIQFCGPSGSDAVEAAIKLAKQCTGRHN
IAAFHGAYHGMTNGAQALMGNLGAKQRRTGLMPDVHFFPFPYGLRCKFGLGGEAGERASIRYIESVLHDQESGMVKPAAM
ILEPIQGEGGVLPASDYWLREIRRITSELGIVLVFDEIQCGVARSGRHFAFEHAGVEPDILVLSKAVGGGLPLSCLVFKK
RFDNWTPGEHAGTFRGTQWAMVAGTRTLQIIQRDGLALNADRMGASLSGRLAALRQDHPCIAEIRGKGLMLGIEIVDPKR
VDALGQPLADGQRAARIQAAALRHGLMIEKGGRHGAVLRFLPPLNITDDQIDFAARAFTHAMQATEQAR

Specific function: Unknown

COG id: COG0160

COG function: function code E; 4-aminobutyrate aminotransferase and related aminotransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI13994255, Length=457, Percent_Identity=27.5711159737418, Blast_Score=149, Evalue=4e-36,
Organism=Homo sapiens, GI37574042, Length=425, Percent_Identity=27.5294117647059, Blast_Score=139, Evalue=8e-33,
Organism=Homo sapiens, GI4557809, Length=416, Percent_Identity=26.9230769230769, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI226442705, Length=425, Percent_Identity=26.5882352941176, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI24119277, Length=423, Percent_Identity=26.241134751773, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI226442709, Length=394, Percent_Identity=26.9035532994924, Blast_Score=122, Evalue=8e-28,
Organism=Homo sapiens, GI284507298, Length=216, Percent_Identity=34.2592592592593, Blast_Score=113, Evalue=4e-25,
Organism=Homo sapiens, GI188536080, Length=386, Percent_Identity=23.5751295336788, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI38679950, Length=386, Percent_Identity=23.5751295336788, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI38679946, Length=386, Percent_Identity=23.5751295336788, Blast_Score=86, Evalue=7e-17,
Organism=Escherichia coli, GI1787560, Length=430, Percent_Identity=34.1860465116279, Blast_Score=201, Evalue=6e-53,
Organism=Escherichia coli, GI1789016, Length=439, Percent_Identity=32.5740318906606, Blast_Score=193, Evalue=2e-50,
Organism=Escherichia coli, GI145693181, Length=415, Percent_Identity=31.8072289156626, Blast_Score=175, Evalue=6e-45,
Organism=Escherichia coli, GI1788044, Length=426, Percent_Identity=28.6384976525822, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1789759, Length=418, Percent_Identity=28.9473684210526, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI1786349, Length=417, Percent_Identity=27.3381294964029, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786991, Length=425, Percent_Identity=28, Blast_Score=108, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI32564660, Length=438, Percent_Identity=29.6803652968037, Blast_Score=172, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI71992977, Length=446, Percent_Identity=26.6816143497758, Blast_Score=145, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI25144271, Length=415, Percent_Identity=26.9879518072289, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI25144274, Length=239, Percent_Identity=31.7991631799163, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17541228, Length=444, Percent_Identity=23.8738738738739, Blast_Score=84, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324432, Length=441, Percent_Identity=29.0249433106576, Blast_Score=159, Evalue=9e-40,
Organism=Saccharomyces cerevisiae, GI6323470, Length=442, Percent_Identity=28.9592760180996, Blast_Score=147, Evalue=4e-36,
Organism=Saccharomyces cerevisiae, GI6321456, Length=404, Percent_Identity=25.990099009901, Blast_Score=97, Evalue=6e-21,
Organism=Drosophila melanogaster, GI28574759, Length=436, Percent_Identity=29.1284403669725, Blast_Score=145, Evalue=4e-35,
Organism=Drosophila melanogaster, GI161085790, Length=434, Percent_Identity=28.5714285714286, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI21357415, Length=416, Percent_Identity=27.4038461538462, Blast_Score=141, Evalue=9e-34,
Organism=Drosophila melanogaster, GI21356575, Length=457, Percent_Identity=27.7899343544858, Blast_Score=131, Evalue=1e-30,
Organism=Drosophila melanogaster, GI281366494, Length=491, Percent_Identity=23.8289205702648, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24667139, Length=491, Percent_Identity=23.8289205702648, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24667143, Length=491, Percent_Identity=23.8289205702648, Blast_Score=88, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR004637
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.76 [H]

Molecular weight: Translated: 50713; Mature: 50713

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKPLYFTLPAPQDIGGPLEPTPQRRFQQGVELRNQERLESEVRSYPRRFPMAIRRAQGA
CCCCEEEECCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IVEDTLGQRYLDCLAGAGALALGHNHPEVTGAVVAAIQSGIPQQALDVATPSKDALIQEI
HHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHH
MGFLPASFAQDSCIQFCGPSGSDAVEAAIKLAKQCTGRHNIAAFHGAYHGMTNGAQALMG
HHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHCCCCCHHHHHHH
NLGAKQRRTGLMPDVHFFPFPYGLRCKFGLGGEAGERASIRYIESVLHDQESGMVKPAAM
HCCCHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHH
ILEPIQGEGGVLPASDYWLREIRRITSELGIVLVFDEIQCGVARSGRHFAFEHAGVEPDI
HHHCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCEEEEECCCCCCCC
LVLSKAVGGGLPLSCLVFKKRFDNWTPGEHAGTFRGTQWAMVAGTRTLQIIQRDGLALNA
EEEEHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCEEEH
DRMGASLSGRLAALRQDHPCIAEIRGKGLMLGIEIVDPKRVDALGQPLADGQRAARIQAA
HHCCCCHHHHHHHHHCCCCCHHHHCCCEEEEEEEEECCHHHHHHCCCCCCCHHHHHHHHH
ALRHGLMIEKGGRHGAVLRFLPPLNITDDQIDFAARAFTHAMQATEQAR
HHHCCCEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNKPLYFTLPAPQDIGGPLEPTPQRRFQQGVELRNQERLESEVRSYPRRFPMAIRRAQGA
CCCCEEEECCCCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IVEDTLGQRYLDCLAGAGALALGHNHPEVTGAVVAAIQSGIPQQALDVATPSKDALIQEI
HHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHH
MGFLPASFAQDSCIQFCGPSGSDAVEAAIKLAKQCTGRHNIAAFHGAYHGMTNGAQALMG
HHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCEEEHHHHHCCCCCHHHHHHH
NLGAKQRRTGLMPDVHFFPFPYGLRCKFGLGGEAGERASIRYIESVLHDQESGMVKPAAM
HCCCHHHHCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHH
ILEPIQGEGGVLPASDYWLREIRRITSELGIVLVFDEIQCGVARSGRHFAFEHAGVEPDI
HHHCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCEEEEECCCCCCCC
LVLSKAVGGGLPLSCLVFKKRFDNWTPGEHAGTFRGTQWAMVAGTRTLQIIQRDGLALNA
EEEEHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCEEEEEECCCCEEEH
DRMGASLSGRLAALRQDHPCIAEIRGKGLMLGIEIVDPKRVDALGQPLADGQRAARIQAA
HHCCCCHHHHHHHHHCCCCCHHHHCCCEEEEEEEEECCHHHHHHCCCCCCCHHHHHHHHH
ALRHGLMIEKGGRHGAVLRFLPPLNITDDQIDFAARAFTHAMQATEQAR
HHHCCCEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11274118; 11481432 [H]