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The map label for this gene is otsB [H]

Identifier: 120612846

GI number: 120612846

Start: 4664965

End: 4665702

Strand: Direct

Name: otsB [H]

Synonym: Aave_4210

Alternate gene names: 120612846

Gene position: 4664965-4665702 (Clockwise)

Preceding gene: 120612844

Following gene: 120612847

Centisome position: 87.15

GC content: 70.05

Gene sequence:

>738_bases
ATGCAAAAGCCACCGTTGCTGACCGCGCGCCACGCGCTGTTTCTCGACTTCGACGGCACGCTTGCCGACATTGCACCGCA
CCCCGATGCGGTGCAGGTGCATCCGGGCGTGGTGCCGGCCCTGCGGGTCCTGCACGAACGCCTGGAGGGCGCCCTGGCCA
TCGCCACGGGCCGCACGCAGGCCGATATCGATCACTTCCTCAGCCCCCTGCAGCTGCCGCTGGCCTGCGAACACGGCGCC
CAGTACCGGATGGTCAACGGCGTCATCGGCGGCGTGCCGGCCCCCGATCTCGCACCCGTGGTGCGTGCCGTGCAGCCGCT
GCTGGACCGTTATCCAGCGCTGGTGCTCGAACGCAAGAGCGCGGGCATGGCGCTGCACTACCGCCAGGCGGTGGAGCTGG
AGCCGCTGTGCCGCGCCGCGCTCGAGCATGCGCTGGCGCAGGCGCCCGGCCTGGAACTCATGCAGGGCAAGTGCGTGCTG
GAGATCAAGCCCTCCGGGCCGAACAAGGGCCGGGCGATCGCCGACTTCATGCGCCAGACGCCGTTCGCGGGCCGCATCCC
CGTGTTCGCGGGAGACGACGTGACCGATGAATACGGCTTCGATGCGGCCCAGGCGCTCGGCGGCATCGGCATCAAGATCG
GAACCGGCGACACCCGGGCGCTGGCACGCTGCGGCGACACCACGGAGCTGCGCGAGTGGCTGTTCCAGATGGCATCGCCG
GAAGGGTTTCCCGCATGA

Upstream 100 bases:

>100_bases
CTGGGTTTTCAAGGCGCGCGCATGGCGGCTGGGCACGCCTACAGGGCGCCAGCCTCGCGGACTACAGGCTCGGCAATGCC
ATCTGGTAAGGTATGTGCCA

Downstream 100 bases:

>100_bases
CATCTCCGGCCTCCACGCCCCCTGCGTCGGCCCCGGCCCCGGCCCCGGCCCCGGCCCCGGCCCCGGCCCCGGCATCCGCT
GCCGCCAGCGCCGCCGCGGC

Product: HAD family hydrolase

Products: NA

Alternate protein names: TPP; Trehalose 6-phosphate phosphatase; Trehalose-phosphatase [H]

Number of amino acids: Translated: 245; Mature: 245

Protein sequence:

>245_residues
MQKPPLLTARHALFLDFDGTLADIAPHPDAVQVHPGVVPALRVLHERLEGALAIATGRTQADIDHFLSPLQLPLACEHGA
QYRMVNGVIGGVPAPDLAPVVRAVQPLLDRYPALVLERKSAGMALHYRQAVELEPLCRAALEHALAQAPGLELMQGKCVL
EIKPSGPNKGRAIADFMRQTPFAGRIPVFAGDDVTDEYGFDAAQALGGIGIKIGTGDTRALARCGDTTELREWLFQMASP
EGFPA

Sequences:

>Translated_245_residues
MQKPPLLTARHALFLDFDGTLADIAPHPDAVQVHPGVVPALRVLHERLEGALAIATGRTQADIDHFLSPLQLPLACEHGA
QYRMVNGVIGGVPAPDLAPVVRAVQPLLDRYPALVLERKSAGMALHYRQAVELEPLCRAALEHALAQAPGLELMQGKCVL
EIKPSGPNKGRAIADFMRQTPFAGRIPVFAGDDVTDEYGFDAAQALGGIGIKIGTGDTRALARCGDTTELREWLFQMASP
EGFPA
>Mature_245_residues
MQKPPLLTARHALFLDFDGTLADIAPHPDAVQVHPGVVPALRVLHERLEGALAIATGRTQADIDHFLSPLQLPLACEHGA
QYRMVNGVIGGVPAPDLAPVVRAVQPLLDRYPALVLERKSAGMALHYRQAVELEPLCRAALEHALAQAPGLELMQGKCVL
EIKPSGPNKGRAIADFMRQTPFAGRIPVFAGDDVTDEYGFDAAQALGGIGIKIGTGDTRALARCGDTTELREWLFQMASP
EGFPA

Specific function: Removes the phosphate from trehalose 6-phosphate to produce free trehalose [H]

COG id: COG1877

COG function: function code G; Trehalose-6-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trehalose phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788207, Length=236, Percent_Identity=43.2203389830509, Blast_Score=187, Evalue=4e-49,
Organism=Drosophila melanogaster, GI19920676, Length=212, Percent_Identity=31.1320754716981, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006379
- InterPro:   IPR003337 [H]

Pfam domain/function: PF02358 Trehalose_PPase [H]

EC number: =3.1.3.12 [H]

Molecular weight: Translated: 26229; Mature: 26229

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKPPLLTARHALFLDFDGTLADIAPHPDAVQVHPGVVPALRVLHERLEGALAIATGRTQ
CCCCCCEEECEEEEEECCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHCCEEEEECCCCH
ADIDHFLSPLQLPLACEHGAQYRMVNGVIGGVPAPDLAPVVRAVQPLLDRYPALVLERKS
HHHHHHHCHHCCCEECCCCCCEEEECCEECCCCCCHHHHHHHHHHHHHHHCHHHEEECCC
AGMALHYRQAVELEPLCRAALEHALAQAPGLELMQGKCVLEIKPSGPNKGRAIADFMRQT
CCEEEEHHHHCCCCHHHHHHHHHHHHHCCCCCEECCCEEEEEECCCCCCCHHHHHHHHHC
PFAGRIPVFAGDDVTDEYGFDAAQALGGIGIKIGTGDTRALARCGDTTELREWLFQMASP
CCCCCCCEEECCCCCHHHCCHHHHHHCCCEEEECCCCHHHHHHCCCHHHHHHHHHHHCCC
EGFPA
CCCCC
>Mature Secondary Structure
MQKPPLLTARHALFLDFDGTLADIAPHPDAVQVHPGVVPALRVLHERLEGALAIATGRTQ
CCCCCCEEECEEEEEECCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHCCEEEEECCCCH
ADIDHFLSPLQLPLACEHGAQYRMVNGVIGGVPAPDLAPVVRAVQPLLDRYPALVLERKS
HHHHHHHCHHCCCEECCCCCCEEEECCEECCCCCCHHHHHHHHHHHHHHHCHHHEEECCC
AGMALHYRQAVELEPLCRAALEHALAQAPGLELMQGKCVLEIKPSGPNKGRAIADFMRQT
CCEEEEHHHHCCCCHHHHHHHHHHHHHCCCCCEECCCEEEEEECCCCCCCHHHHHHHHHC
PFAGRIPVFAGDDVTDEYGFDAAQALGGIGIKIGTGDTRALARCGDTTELREWLFQMASP
CCCCCCCEEECCCCCHHHCCHHHHHHCCCEEEECCCCHHHHHHCCCHHHHHHHHHHHCCC
EGFPA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]