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The map label for this gene is azlB [H]

Identifier: 120612824

GI number: 120612824

Start: 4640018

End: 4640584

Strand: Reverse

Name: azlB [H]

Synonym: Aave_4188

Alternate gene names: 120612824

Gene position: 4640584-4640018 (Counterclockwise)

Preceding gene: 120612830

Following gene: 120612823

Centisome position: 86.69

GC content: 68.08

Gene sequence:

>567_bases
ATGGCCGCGTTCCACCCGGACAAACCCGGGGAGGGCGCCGGCGGGCCGTGCCCGCACACGCGGGGCTTCGTAGAATCCTG
TGCCATGAGCGCTTCCCACGCACTGGACCGGCTTGATCGGGCGATCCTGCGCTGCCTTCAGGACAACGGCCGCGAAACCT
ACGACGTCATCGGCGAACAGGTGGGCCTGTCGCCCAGCGCGGTGCTGCGCCGCGCCAAGCGCCTGGAAGATGCCGGCGTG
ATCGACCGCTACGTCGCCCTGGTGCGTCCGGAGGCCGTGGGCCTGGGCCTCACGGCCTACCTCAACGTCCGCCTGGAAAA
GCACACCGAAAGCCACAAGCGCAACCCCATGGACCTGTTCCGCGCGAGCGTCCAGACCTGGCCCGAAGTGGTGGAGTGCT
CCGCCCTCACCGGCGAGATGGACTACCTGCTGCGCGTGGTCGTGGCCGACATGGCCCACTACAGCCGGTTCATCATGGAC
ACCCTGCTCAAGCACCCCAGCGTGCAGGACTGCAAGACCAGCTTCGTGCTCGACCGCGTGAAGAGCACCACCGCGGTGCC
CGTCTGA

Upstream 100 bases:

>100_bases
CGCGAAGGGTTCCGTTCATGGTTGCTTGTCTCCGTCGTTGTAGTGATGCGCACAAAAAAGAACGACCGTTCTTTTTTGTG
AATTCCATTATTCGCCGCCC

Downstream 100 bases:

>100_bases
CACATTGGCGACAGATTTGCCATTGAATAAGTAGCAACCGAGCGCCGAGGGCAGGGCGTCTGGAACTGCCCGTGCCCGAG
AGTTCGGAAGGCCGGCGTGT

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MAAFHPDKPGEGAGGPCPHTRGFVESCAMSASHALDRLDRAILRCLQDNGRETYDVIGEQVGLSPSAVLRRAKRLEDAGV
IDRYVALVRPEAVGLGLTAYLNVRLEKHTESHKRNPMDLFRASVQTWPEVVECSALTGEMDYLLRVVVADMAHYSRFIMD
TLLKHPSVQDCKTSFVLDRVKSTTAVPV

Sequences:

>Translated_188_residues
MAAFHPDKPGEGAGGPCPHTRGFVESCAMSASHALDRLDRAILRCLQDNGRETYDVIGEQVGLSPSAVLRRAKRLEDAGV
IDRYVALVRPEAVGLGLTAYLNVRLEKHTESHKRNPMDLFRASVQTWPEVVECSALTGEMDYLLRVVVADMAHYSRFIMD
TLLKHPSVQDCKTSFVLDRVKSTTAVPV
>Mature_187_residues
AAFHPDKPGEGAGGPCPHTRGFVESCAMSASHALDRLDRAILRCLQDNGRETYDVIGEQVGLSPSAVLRRAKRLEDAGVI
DRYVALVRPEAVGLGLTAYLNVRLEKHTESHKRNPMDLFRASVQTWPEVVECSALTGEMDYLLRVVVADMAHYSRFIMDT
LLKHPSVQDCKTSFVLDRVKSTTAVPV

Specific function: Transcriptional repressor of the azlBCD operon involved in branched-chain amino acid transport [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081742, Length=155, Percent_Identity=36.7741935483871, Blast_Score=103, Evalue=8e-24,
Organism=Escherichia coli, GI1787116, Length=154, Percent_Identity=35.0649350649351, Blast_Score=101, Evalue=3e-23,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 20763; Mature: 20632

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAFHPDKPGEGAGGPCPHTRGFVESCAMSASHALDRLDRAILRCLQDNGRETYDVIGEQ
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
VGLSPSAVLRRAKRLEDAGVIDRYVALVRPEAVGLGLTAYLNVRLEKHTESHKRNPMDLF
HCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHCCCHHHHH
RASVQTWPEVVECSALTGEMDYLLRVVVADMAHYSRFIMDTLLKHPSVQDCKTSFVLDRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
KSTTAVPV
HHHCCCCC
>Mature Secondary Structure 
AAFHPDKPGEGAGGPCPHTRGFVESCAMSASHALDRLDRAILRCLQDNGRETYDVIGEQ
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
VGLSPSAVLRRAKRLEDAGVIDRYVALVRPEAVGLGLTAYLNVRLEKHTESHKRNPMDLF
HCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHCCCHHHHH
RASVQTWPEVVECSALTGEMDYLLRVVVADMAHYSRFIMDTLLKHPSVQDCKTSFVLDRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
KSTTAVPV
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9287000; 9308178; 9384377 [H]