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The map label for this gene is mmgC [H]

Identifier: 120612726

GI number: 120612726

Start: 4541673

End: 4543478

Strand: Reverse

Name: mmgC [H]

Synonym: Aave_4089

Alternate gene names: 120612726

Gene position: 4543478-4541673 (Counterclockwise)

Preceding gene: 120612727

Following gene: 120612725

Centisome position: 84.88

GC content: 64.73

Gene sequence:

>1806_bases
ATGCCGACCTACACGCCCTCCCTGCGCGACATGCAATTCGTCCTCCACGAGGTTTTCCGGGTCACGGAGGAGTTCAAGGC
GATCCCGCGCCATGCGGAGGTGGATGCCGACACCGTGAATGCCGTGCTGGAAGAGGCCGGCAAGTTCGCCGCGGGCGTGG
CGTTCCCGCTCAACATGAGCGGCGACGAGGAGGGCTGCACGCTGGACAAGGCCACGCACGAAGTGACCACGCCCAAGGGC
TTCAAGGATGCCTACGCGCAGTATGTGGAAGGCGGCTGGGCGGCGCTGTCGTGCGATCCGGAGTATGGCGGCCAGGGCCT
GCCGTTCGTCGTGAACCAGTGCCTCTATGAAATGCTCAACAGCGCCAACCAGGCCTGGACCATGTATCCGGGGCTGTCGC
ACGGCGCCTACGAGGCGTTGCATGCGCACGGGACCGAAGAGCAGAAGAAGCTCTACCTGCCCAAGCTCACCAGCGGCGAA
TGGACCGGCACCATGTGCCTGACCGAGCCCCACTGCGGCACCGACCTGGGCCTGCTGCGCACCAGGGCCGAGCCCGTGGC
CGGCGCGCCCGAGGGTACGTACAAGATCACGGGCAACAAGATCTTCATCAGCGCGGGCGAACATGATTTCACCGAGAACA
TCGTGCACCTGGTGCTCGCCCGCCTGCCGGATGCGCCGAAGGGCAGCAAGGGCATCAGCCTGTTCGTGGTGCCCAAGTAC
AAGGTGAACGCCGACGGCTCGATCGGCGAGCGCAACCCGATCTATTGCACGGGCCTGGAGCACAAGATGGGCATCCATGG
CAACGCCACCGCCCAGATCTCCATCGACGGCGCCATCGGCACGCTGGTGGGCCAGCCGCACAAGGGCCTGCAGGCCATGT
TCGTGATGATGAACGCCGCCCGCCTGGGCGTGGGCAACCAGTCGCTGGGCCTGACCGAAGTGGCTTTCCAGAACGCGCTG
GCCTATGCCAAGGACCGCATCCAGATGCGCAGCCTGTCGGGCACGAAGGCCAAGGACAAGGAGGCCGATCCGATCATCGT
GCACCCCGACGTGCGCAAGATGCTGCTCACGGCCAAGGCCTACGCCGAAGGCGCCCGCGCGCTGCAGATCTACTGCACGC
TGCTGCTGGACAAGGCGCACAGCCATCCCGACGAGAAGGTGCGCAAGGACAGTGATGAACTCGTGGCGCTGCTCACGCCC
ATCGTGAAGGCCTTCATCACCGACAACGGGCATATTTCCACCAATGCCTGCATGCAGGTCTTCGGTGGCCACGGCTTCAT
CAAGGAATGGGGCATGGAGCAGTTCGTGCGGGACAACCGCATCAACATGATCTACGAAGGCACGAACACCGTGCAGTCGC
TGGACCTGCTGGGCCGCAAGATCCTCGGCAACAACGGCGCCACGCTCAAGAAGTTCGGCAAGCTCGTGGGCAAGCTGGTC
GAGGAAGAGGGCGTGAACGAGAAGATGGCCGAGTTCATCAACCCCATCGCCTACCTGGGCGACCAGATGACGAAGTTCAC
CACCGAGATCGGCTTCAAGGGTTTCCAGAACCCCGACGAGGTGGGCGCCGCGGCCGTGGACTACCTGCGTGTGGCGGGTC
ACCTGGTGTTCGGCTACATGTTCGCCCGCATGGCCCAGGTGGCCCTGCGGGAGATCGCTGCCGGCAATACCGACCCGTTC
TACCAGGCCAAGCTGCAGACGGCGCGCTTCTACTTCGCCAAGCTGTTCCCCGAGACGGCGACCCTGATGCGCACCGCGCG
CACCGGTGCCAAGCCGCTGATGGACACGGACGCCGCCCTGGCCTGA

Upstream 100 bases:

>100_bases
TCCTCGCCCGCTATGCCGCCAGGCCGGCGGGTTGAACGTTTTTTTCGTCTTTTCCGCCTACGCATTCCACCATCCAACGC
ACCGAACTAGGAGCCCATCC

Downstream 100 bases:

>100_bases
CCCCGTCGCCCCGGCCTTCATTTCAATCAGACCACAGGGATGCCGCTATGAGAACCGCTTTGTTGGCTATTGCCTTGGCA
GCCGCCGCGCTGCCCTCCTG

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 601; Mature: 600

Protein sequence:

>601_residues
MPTYTPSLRDMQFVLHEVFRVTEEFKAIPRHAEVDADTVNAVLEEAGKFAAGVAFPLNMSGDEEGCTLDKATHEVTTPKG
FKDAYAQYVEGGWAALSCDPEYGGQGLPFVVNQCLYEMLNSANQAWTMYPGLSHGAYEALHAHGTEEQKKLYLPKLTSGE
WTGTMCLTEPHCGTDLGLLRTRAEPVAGAPEGTYKITGNKIFISAGEHDFTENIVHLVLARLPDAPKGSKGISLFVVPKY
KVNADGSIGERNPIYCTGLEHKMGIHGNATAQISIDGAIGTLVGQPHKGLQAMFVMMNAARLGVGNQSLGLTEVAFQNAL
AYAKDRIQMRSLSGTKAKDKEADPIIVHPDVRKMLLTAKAYAEGARALQIYCTLLLDKAHSHPDEKVRKDSDELVALLTP
IVKAFITDNGHISTNACMQVFGGHGFIKEWGMEQFVRDNRINMIYEGTNTVQSLDLLGRKILGNNGATLKKFGKLVGKLV
EEEGVNEKMAEFINPIAYLGDQMTKFTTEIGFKGFQNPDEVGAAAVDYLRVAGHLVFGYMFARMAQVALREIAAGNTDPF
YQAKLQTARFYFAKLFPETATLMRTARTGAKPLMDTDAALA

Sequences:

>Translated_601_residues
MPTYTPSLRDMQFVLHEVFRVTEEFKAIPRHAEVDADTVNAVLEEAGKFAAGVAFPLNMSGDEEGCTLDKATHEVTTPKG
FKDAYAQYVEGGWAALSCDPEYGGQGLPFVVNQCLYEMLNSANQAWTMYPGLSHGAYEALHAHGTEEQKKLYLPKLTSGE
WTGTMCLTEPHCGTDLGLLRTRAEPVAGAPEGTYKITGNKIFISAGEHDFTENIVHLVLARLPDAPKGSKGISLFVVPKY
KVNADGSIGERNPIYCTGLEHKMGIHGNATAQISIDGAIGTLVGQPHKGLQAMFVMMNAARLGVGNQSLGLTEVAFQNAL
AYAKDRIQMRSLSGTKAKDKEADPIIVHPDVRKMLLTAKAYAEGARALQIYCTLLLDKAHSHPDEKVRKDSDELVALLTP
IVKAFITDNGHISTNACMQVFGGHGFIKEWGMEQFVRDNRINMIYEGTNTVQSLDLLGRKILGNNGATLKKFGKLVGKLV
EEEGVNEKMAEFINPIAYLGDQMTKFTTEIGFKGFQNPDEVGAAAVDYLRVAGHLVFGYMFARMAQVALREIAAGNTDPF
YQAKLQTARFYFAKLFPETATLMRTARTGAKPLMDTDAALA
>Mature_600_residues
PTYTPSLRDMQFVLHEVFRVTEEFKAIPRHAEVDADTVNAVLEEAGKFAAGVAFPLNMSGDEEGCTLDKATHEVTTPKGF
KDAYAQYVEGGWAALSCDPEYGGQGLPFVVNQCLYEMLNSANQAWTMYPGLSHGAYEALHAHGTEEQKKLYLPKLTSGEW
TGTMCLTEPHCGTDLGLLRTRAEPVAGAPEGTYKITGNKIFISAGEHDFTENIVHLVLARLPDAPKGSKGISLFVVPKYK
VNADGSIGERNPIYCTGLEHKMGIHGNATAQISIDGAIGTLVGQPHKGLQAMFVMMNAARLGVGNQSLGLTEVAFQNALA
YAKDRIQMRSLSGTKAKDKEADPIIVHPDVRKMLLTAKAYAEGARALQIYCTLLLDKAHSHPDEKVRKDSDELVALLTPI
VKAFITDNGHISTNACMQVFGGHGFIKEWGMEQFVRDNRINMIYEGTNTVQSLDLLGRKILGNNGATLKKFGKLVGKLVE
EEGVNEKMAEFINPIAYLGDQMTKFTTEIGFKGFQNPDEVGAAAVDYLRVAGHLVFGYMFARMAQVALREIAAGNTDPFY
QAKLQTARFYFAKLFPETATLMRTARTGAKPLMDTDAALA

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=375, Percent_Identity=26.9333333333333, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI76496475, Length=396, Percent_Identity=28.2828282828283, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI4557235, Length=396, Percent_Identity=28.2828282828283, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI7656849, Length=384, Percent_Identity=26.0416666666667, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI21361497, Length=373, Percent_Identity=23.5924932975871, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI4557233, Length=371, Percent_Identity=23.989218328841, Blast_Score=93, Evalue=7e-19,
Organism=Homo sapiens, GI226958412, Length=398, Percent_Identity=25.3768844221106, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI226958414, Length=376, Percent_Identity=26.063829787234, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI4501857, Length=324, Percent_Identity=25, Blast_Score=89, Evalue=2e-17,
Organism=Homo sapiens, GI4557231, Length=318, Percent_Identity=25.7861635220126, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI187960098, Length=318, Percent_Identity=25.7861635220126, Blast_Score=72, Evalue=2e-12,
Organism=Escherichia coli, GI87082384, Length=407, Percent_Identity=26.044226044226, Blast_Score=100, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17508101, Length=369, Percent_Identity=28.1842818428184, Blast_Score=112, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI17533517, Length=428, Percent_Identity=25.9345794392523, Blast_Score=108, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI17506239, Length=368, Percent_Identity=26.9021739130435, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17569725, Length=374, Percent_Identity=27.5401069518717, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI86563383, Length=420, Percent_Identity=25.4761904761905, Blast_Score=96, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI86563381, Length=420, Percent_Identity=25.4761904761905, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI71985184, Length=427, Percent_Identity=26.463700234192, Blast_Score=96, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17534899, Length=375, Percent_Identity=29.0666666666667, Blast_Score=96, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17538396, Length=381, Percent_Identity=25.4593175853018, Blast_Score=79, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI32563615, Length=233, Percent_Identity=27.8969957081545, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71990804, Length=245, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17534353, Length=339, Percent_Identity=27.7286135693215, Blast_Score=72, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71985192, Length=299, Percent_Identity=27.4247491638796, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17570075, Length=388, Percent_Identity=23.4536082474227, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71982178, Length=242, Percent_Identity=28.099173553719, Blast_Score=66, Evalue=4e-11,
Organism=Drosophila melanogaster, GI21356377, Length=376, Percent_Identity=25.531914893617, Blast_Score=109, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24666513, Length=367, Percent_Identity=25.0681198910082, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24646207, Length=390, Percent_Identity=23.3333333333333, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI281363737, Length=421, Percent_Identity=25.1781472684086, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21355753, Length=381, Percent_Identity=25.9842519685039, Blast_Score=83, Evalue=5e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 65588; Mature: 65457

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTYTPSLRDMQFVLHEVFRVTEEFKAIPRHAEVDADTVNAVLEEAGKFAAGVAFPLNMS
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHCCEEEEECCC
GDEEGCTLDKATHEVTTPKGFKDAYAQYVEGGWAALSCDPEYGGQGLPFVVNQCLYEMLN
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHH
SANQAWTMYPGLSHGAYEALHAHGTEEQKKLYLPKLTSGEWTGTMCLTEPHCGTDLGLLR
CCCCEEEECCCCCCHHHHHHHHCCCCHHHEEECCCCCCCCCCEEEEEECCCCCCCHHHHH
TRAEPVAGAPEGTYKITGNKIFISAGEHDFTENIVHLVLARLPDAPKGSKGISLFVVPKY
HCCCCCCCCCCCCEEEECCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECE
KVNADGSIGERNPIYCTGLEHKMGIHGNATAQISIDGAIGTLVGQPHKGLQAMFVMMNAA
EECCCCCCCCCCCEEEECCCCCCCCCCCCEEEEEECCCHHHHCCCCCHHHHHHHHHHHHH
RLGVGNQSLGLTEVAFQNALAYAKDRIQMRSLSGTKAKDKEADPIIVHPDVRKMLLTAKA
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCHHHHHHHHHHH
YAEGARALQIYCTLLLDKAHSHPDEKVRKDSDELVALLTPIVKAFITDNGHISTNACMQV
HHCCHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
FGGHGFIKEWGMEQFVRDNRINMIYEGTNTVQSLDLLGRKILGNNGATLKKFGKLVGKLV
HCCCCHHHHHCHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
EEEGVNEKMAEFINPIAYLGDQMTKFTTEIGFKGFQNPDEVGAAAVDYLRVAGHLVFGYM
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FARMAQVALREIAAGNTDPFYQAKLQTARFYFAKLFPETATLMRTARTGAKPLMDTDAAL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
A
C
>Mature Secondary Structure 
PTYTPSLRDMQFVLHEVFRVTEEFKAIPRHAEVDADTVNAVLEEAGKFAAGVAFPLNMS
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHCCEEEEECCC
GDEEGCTLDKATHEVTTPKGFKDAYAQYVEGGWAALSCDPEYGGQGLPFVVNQCLYEMLN
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHHHHHHHHH
SANQAWTMYPGLSHGAYEALHAHGTEEQKKLYLPKLTSGEWTGTMCLTEPHCGTDLGLLR
CCCCEEEECCCCCCHHHHHHHHCCCCHHHEEECCCCCCCCCCEEEEEECCCCCCCHHHHH
TRAEPVAGAPEGTYKITGNKIFISAGEHDFTENIVHLVLARLPDAPKGSKGISLFVVPKY
HCCCCCCCCCCCCEEEECCEEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEEEECE
KVNADGSIGERNPIYCTGLEHKMGIHGNATAQISIDGAIGTLVGQPHKGLQAMFVMMNAA
EECCCCCCCCCCCEEEECCCCCCCCCCCCEEEEEECCCHHHHCCCCCHHHHHHHHHHHHH
RLGVGNQSLGLTEVAFQNALAYAKDRIQMRSLSGTKAKDKEADPIIVHPDVRKMLLTAKA
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCHHHHHHHHHHH
YAEGARALQIYCTLLLDKAHSHPDEKVRKDSDELVALLTPIVKAFITDNGHISTNACMQV
HHCCHHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
FGGHGFIKEWGMEQFVRDNRINMIYEGTNTVQSLDLLGRKILGNNGATLKKFGKLVGKLV
HCCCCHHHHHCHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
EEEGVNEKMAEFINPIAYLGDQMTKFTTEIGFKGFQNPDEVGAAAVDYLRVAGHLVFGYM
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FARMAQVALREIAAGNTDPFYQAKLQTARFYFAKLFPETATLMRTARTGAKPLMDTDAAL
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]