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The map label for this gene is pkn6 [H]

Identifier: 120612691

GI number: 120612691

Start: 4503820

End: 4505757

Strand: Reverse

Name: pkn6 [H]

Synonym: Aave_4054

Alternate gene names: 120612691

Gene position: 4505757-4503820 (Counterclockwise)

Preceding gene: 120612693

Following gene: 120612690

Centisome position: 84.18

GC content: 72.08

Gene sequence:

>1938_bases
ATGTCCGCTCCCACCCTCGTCACCGAACCCCAGAGCGAAGCCCACCACGTGGACGCATTGCCTGCGGGATCCCGCCTCGG
AGAATTCGAGGTGGTCTCGCTGCTCGGCGTCGGGGGCTTCGGCATGGTCTACAAGGCATTCGACCATTCGCTGCTCCGGT
TCGTGGCCATCAAGGAATACATGCCCACGGCGCTGGCCGCCCGTGCGCACGGGCAGTCGCTCTGGGTGCGCTCCTCCTCG
CACGAGCAGTCGTTCCAGGCGGGCCTGGCGTCCTTCGTGGCCGAGGCCCGGCTGCTCGCGCAGTTCGACCATCCCTCGCT
GGTGAAGGTCTTCCGTTTCTGGGAAGCCAACCAGACCGCCTACATGGTGATGCCGCTCTATGCGGGCATGACGCTCAAGC
AGGCGCGCGCCCACATGCGCACGCCGCCGCCCGAGGCCTGGCTGCGCAAGGTGCTCTGGTCCGTGCTGGGTGCGCTGCGG
GTGCTGCACGAGGGCCAGACCCTGCACCGCGACATCTCTCCCGACAACATCTTCCTGCAGGACTCGGGGCTGCCGGTGCT
GCTGGACCTCGGCGCTGCCCGGCATGCGATCACCGACCATTCCCACCGGCTCACGGCGGTGCTCAAGGTCAACTACGCGC
CGATCGAGCAGTACAACGACGAGGGCAACGACCTGCGCCAGGGGCCCTGGAGCGATCTGTATTCCGTGGGGGCCGTCGTG
CATGGCTGCCTGTGCAACGACACGCCGCTGCCCGCGACCCTGCGCGCGATCCGTGACCGGATGGTGCCGTTCTCCCGTGT
CGCCAAGACCGTGAAGCGCCAGTTCGGCGTCGAGTATTCGCCGCCCTTCGTGGCCGCTGTCTCGCAGACGCTCGCGCTGC
AGCCGCAGGACCGGCCGCAGAGCATCGACGATTTCCTGCGCACCCTCGAGATGACGGCCCCGCCGGAAGGCATGGAGCAA
TTCGACTTCCGCGCCGAACTCGGCGACATCTGGGTCGAGCCGGCCGATCGCCGCGCCACGGGGGTGGCCGTTCCGATGAT
CGACATCACGTCCGTGCCGGCGCCGATGTCGGGCCTTCCGGTGCCCGAACCCATGGCTGCGCCCGTGCTGGCTCCCGAGC
CAGTCGCCGTCACCACCGTGGTGCGCCGCGGTGCCGCGCCTCCCGTCGAGCCCGAGCGTGCCCCCCGCGACATGGCGCCA
GGCGGCGATACGGTTTTCCTCGACAGTGCGGCCGAGGCCGGCGACTCCTGGTTCGAGCCTGCGGGCGTACACCGGCCGGG
CGGTACAGCCACGCCCGGAGCGGGGGAAGCGGCCGTGGACAAAGCCGGGTCTGCGGCGGGCCGGCGGTCGCGCGCATGGA
TCATGGCGGGGGTGGCGGCCGTGGCTCTGGTCGCCGCCGCTGGCGGGGGATGGTGGGCCGCGCGTTCCGCCGACGACCAG
CCGGCGGTGGCGGCAGCGGCCGTGCCCAGGACCCCGGAAGAGGAGATCATCACGGAAACGGTGGAGCCTGCTCCTCCTCC
TGCGGCCGCTGCGGCCCAGGGGGCATCCTCTGCCCTGGCGGTGCCGGACCCCGCGCCCCCGGGTTCGGCAGAGGCCGGCA
CCCGATCCGCGGCAGCCTCCGCGCCGGGCGCAACTGCGGCTGCGGCGTCTTCTCCGCGCAACCGCCCGCCGGTGCGCAAG
ACGGCGGAGGCTGCCGTGGCGGCCGCCCCCGCCACGCCCACGGCATCCCAGGCCGCGCTGGCGCCTGCGCCGCCACCGAA
GCCCGCCCCGCGCGTGATCGGCCCGGACGAGGCGTGCGCGGATGCCGGCTTCCTGGCCCGGCCCATGTGCATCCACCAGG
AATGCCAGCGTCCCGCGGTGGCGAACCATCCCCTGTGCGTGGAGAACCGCCGCCGGCTGGAGGCCGAGGAGCGCCGCCGG
CTGATGCAGCCGCAGTGA

Upstream 100 bases:

>100_bases
TTGCCCGTCCACGGTCCGCTTGCTGCATGATGGCGGCCATCGGCCGCTCCGGCAGACACCGCCGTGCCGTGGCGGCCCCC
TGGATTTTTGCTTTTTCCCT

Downstream 100 bases:

>100_bases
GCGCAGGCGGCGCTCCTGCAGAGCGCTGTCGCTGCGTGCCGGAAGCGCCACGCCGATTGCCAGGGGCGGCTTCCGGGAGG
GGAATTGCGTTGACCCGAAG

Product: serine/threonine protein kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 645; Mature: 644

Protein sequence:

>645_residues
MSAPTLVTEPQSEAHHVDALPAGSRLGEFEVVSLLGVGGFGMVYKAFDHSLLRFVAIKEYMPTALAARAHGQSLWVRSSS
HEQSFQAGLASFVAEARLLAQFDHPSLVKVFRFWEANQTAYMVMPLYAGMTLKQARAHMRTPPPEAWLRKVLWSVLGALR
VLHEGQTLHRDISPDNIFLQDSGLPVLLDLGAARHAITDHSHRLTAVLKVNYAPIEQYNDEGNDLRQGPWSDLYSVGAVV
HGCLCNDTPLPATLRAIRDRMVPFSRVAKTVKRQFGVEYSPPFVAAVSQTLALQPQDRPQSIDDFLRTLEMTAPPEGMEQ
FDFRAELGDIWVEPADRRATGVAVPMIDITSVPAPMSGLPVPEPMAAPVLAPEPVAVTTVVRRGAAPPVEPERAPRDMAP
GGDTVFLDSAAEAGDSWFEPAGVHRPGGTATPGAGEAAVDKAGSAAGRRSRAWIMAGVAAVALVAAAGGGWWAARSADDQ
PAVAAAAVPRTPEEEIITETVEPAPPPAAAAAQGASSALAVPDPAPPGSAEAGTRSAAASAPGATAAAASSPRNRPPVRK
TAEAAVAAAPATPTASQAALAPAPPPKPAPRVIGPDEACADAGFLARPMCIHQECQRPAVANHPLCVENRRRLEAEERRR
LMQPQ

Sequences:

>Translated_645_residues
MSAPTLVTEPQSEAHHVDALPAGSRLGEFEVVSLLGVGGFGMVYKAFDHSLLRFVAIKEYMPTALAARAHGQSLWVRSSS
HEQSFQAGLASFVAEARLLAQFDHPSLVKVFRFWEANQTAYMVMPLYAGMTLKQARAHMRTPPPEAWLRKVLWSVLGALR
VLHEGQTLHRDISPDNIFLQDSGLPVLLDLGAARHAITDHSHRLTAVLKVNYAPIEQYNDEGNDLRQGPWSDLYSVGAVV
HGCLCNDTPLPATLRAIRDRMVPFSRVAKTVKRQFGVEYSPPFVAAVSQTLALQPQDRPQSIDDFLRTLEMTAPPEGMEQ
FDFRAELGDIWVEPADRRATGVAVPMIDITSVPAPMSGLPVPEPMAAPVLAPEPVAVTTVVRRGAAPPVEPERAPRDMAP
GGDTVFLDSAAEAGDSWFEPAGVHRPGGTATPGAGEAAVDKAGSAAGRRSRAWIMAGVAAVALVAAAGGGWWAARSADDQ
PAVAAAAVPRTPEEEIITETVEPAPPPAAAAAQGASSALAVPDPAPPGSAEAGTRSAAASAPGATAAAASSPRNRPPVRK
TAEAAVAAAPATPTASQAALAPAPPPKPAPRVIGPDEACADAGFLARPMCIHQECQRPAVANHPLCVENRRRLEAEERRR
LMQPQ
>Mature_644_residues
SAPTLVTEPQSEAHHVDALPAGSRLGEFEVVSLLGVGGFGMVYKAFDHSLLRFVAIKEYMPTALAARAHGQSLWVRSSSH
EQSFQAGLASFVAEARLLAQFDHPSLVKVFRFWEANQTAYMVMPLYAGMTLKQARAHMRTPPPEAWLRKVLWSVLGALRV
LHEGQTLHRDISPDNIFLQDSGLPVLLDLGAARHAITDHSHRLTAVLKVNYAPIEQYNDEGNDLRQGPWSDLYSVGAVVH
GCLCNDTPLPATLRAIRDRMVPFSRVAKTVKRQFGVEYSPPFVAAVSQTLALQPQDRPQSIDDFLRTLEMTAPPEGMEQF
DFRAELGDIWVEPADRRATGVAVPMIDITSVPAPMSGLPVPEPMAAPVLAPEPVAVTTVVRRGAAPPVEPERAPRDMAPG
GDTVFLDSAAEAGDSWFEPAGVHRPGGTATPGAGEAAVDKAGSAAGRRSRAWIMAGVAAVALVAAAGGGWWAARSADDQP
AVAAAAVPRTPEEEIITETVEPAPPPAAAAAQGASSALAVPDPAPPGSAEAGTRSAAASAPGATAAAASSPRNRPPVRKT
AEAAVAAAPATPTASQAALAPAPPPKPAPRVIGPDEACADAGFLARPMCIHQECQRPAVANHPLCVENRRRLEAEERRRL
MQPQ

Specific function: Pkn5 and pkn6 may have reciprocal roles in growth and development. Pkn6 may be a transmembrane sensor of external signals for development [H]

COG id: COG0515

COG function: function code RTKL; Serine/threonine protein kinase

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain [H]

Homologues:

Organism=Homo sapiens, GI207029299, Length=192, Percent_Identity=30.2083333333333, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI37596297, Length=169, Percent_Identity=23.6686390532544, Blast_Score=68, Evalue=3e-11,
Organism=Homo sapiens, GI4885583, Length=226, Percent_Identity=28.7610619469027, Blast_Score=67, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI86562808, Length=182, Percent_Identity=29.6703296703297, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17565634, Length=217, Percent_Identity=25.8064516129032, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6320685, Length=246, Percent_Identity=24.390243902439, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324557, Length=221, Percent_Identity=25.3393665158371, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI18858209, Length=227, Percent_Identity=29.5154185022026, Blast_Score=80, Evalue=4e-15,
Organism=Drosophila melanogaster, GI45552745, Length=241, Percent_Identity=24.4813278008299, Blast_Score=79, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45552743, Length=241, Percent_Identity=24.4813278008299, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI62471747, Length=241, Percent_Identity=24.4813278008299, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45552741, Length=241, Percent_Identity=24.4813278008299, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI45552747, Length=241, Percent_Identity=24.4813278008299, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281363794, Length=241, Percent_Identity=24.4813278008299, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281363796, Length=241, Percent_Identity=24.4813278008299, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281363800, Length=241, Percent_Identity=24.4813278008299, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45552739, Length=241, Percent_Identity=24.4813278008299, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45552731, Length=241, Percent_Identity=24.4813278008299, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45552735, Length=241, Percent_Identity=24.4813278008299, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45552737, Length=241, Percent_Identity=24.4813278008299, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI45552733, Length=241, Percent_Identity=24.4813278008299, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281363798, Length=264, Percent_Identity=24.6212121212121, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45552749, Length=264, Percent_Identity=24.6212121212121, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI62471745, Length=264, Percent_Identity=24.6212121212121, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI62471749, Length=264, Percent_Identity=24.6212121212121, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI45552751, Length=264, Percent_Identity=24.6212121212121, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011009
- InterPro:   IPR013229
- InterPro:   IPR000719
- InterPro:   IPR017442
- InterPro:   IPR008266 [H]

Pfam domain/function: PF08308 PEGA; PF00069 Pkinase [H]

EC number: =2.7.11.1 [H]

Molecular weight: Translated: 68178; Mature: 68047

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00107 PROTEIN_KINASE_ATP ; PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAPTLVTEPQSEAHHVDALPAGSRLGEFEVVSLLGVGGFGMVYKAFDHSLLRFVAIKEY
CCCCCCCCCCCCHHCCCCCCCCCCCCCCHHEEHHHCCCCHHHHHHHHHHHHHHHHHHHHH
MPTALAARAHGQSLWVRSSSHEQSFQAGLASFVAEARLLAQFDHPSLVKVFRFWEANQTA
HHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCE
YMVMPLYAGMTLKQARAHMRTPPPEAWLRKVLWSVLGALRVLHEGQTLHRDISPDNIFLQ
EEEEHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEEE
DSGLPVLLDLGAARHAITDHSHRLTAVLKVNYAPIEQYNDEGNDLRQGPWSDLYSVGAVV
CCCCEEEEECCCHHHHHCCCCCEEEEEEEECCCHHHHHCCCCCCCCCCCHHHHHHHHHHH
HGCLCNDTPLPATLRAIRDRMVPFSRVAKTVKRQFGVEYSPPFVAAVSQTLALQPQDRPQ
HHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCC
SIDDFLRTLEMTAPPEGMEQFDFRAELGDIWVEPADRRATGVAVPMIDITSVPAPMSGLP
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHEECCCCCCCCCCEEEEEEEECCCCCCCCCCC
VPEPMAAPVLAPEPVAVTTVVRRGAAPPVEPERAPRDMAPGGDTVFLDSAAEAGDSWFEP
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCHHHCCCCCCCC
AGVHRPGGTATPGAGEAAVDKAGSAAGRRSRAWIMAGVAAVALVAAAGGGWWAARSADDQ
CCCCCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCC
PAVAAAAVPRTPEEEIITETVEPAPPPAAAAAQGASSALAVPDPAPPGSAEAGTRSAAAS
CCCHHHCCCCCCHHHHHHHCCCCCCCCHHHHHCCCCCEEECCCCCCCCCCCCCCCHHHCC
APGATAAAASSPRNRPPVRKTAEAAVAAAPATPTASQAALAPAPPPKPAPRVIGPDEACA
CCCCHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
DAGFLARPMCIHQECQRPAVANHPLCVENRRRLEAEERRRLMQPQ
CCCHHHCCHHHHHHHCCCCCCCCCCCCCHHHCCCHHHHHHCCCCC
>Mature Secondary Structure 
SAPTLVTEPQSEAHHVDALPAGSRLGEFEVVSLLGVGGFGMVYKAFDHSLLRFVAIKEY
CCCCCCCCCCCHHCCCCCCCCCCCCCCHHEEHHHCCCCHHHHHHHHHHHHHHHHHHHHH
MPTALAARAHGQSLWVRSSSHEQSFQAGLASFVAEARLLAQFDHPSLVKVFRFWEANQTA
HHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCE
YMVMPLYAGMTLKQARAHMRTPPPEAWLRKVLWSVLGALRVLHEGQTLHRDISPDNIFLQ
EEEEHHHCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCEEEEE
DSGLPVLLDLGAARHAITDHSHRLTAVLKVNYAPIEQYNDEGNDLRQGPWSDLYSVGAVV
CCCCEEEEECCCHHHHHCCCCCEEEEEEEECCCHHHHHCCCCCCCCCCCHHHHHHHHHHH
HGCLCNDTPLPATLRAIRDRMVPFSRVAKTVKRQFGVEYSPPFVAAVSQTLALQPQDRPQ
HHHHCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCC
SIDDFLRTLEMTAPPEGMEQFDFRAELGDIWVEPADRRATGVAVPMIDITSVPAPMSGLP
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHEECCCCCCCCCCEEEEEEEECCCCCCCCCCC
VPEPMAAPVLAPEPVAVTTVVRRGAAPPVEPERAPRDMAPGGDTVFLDSAAEAGDSWFEP
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEECCHHHCCCCCCCC
AGVHRPGGTATPGAGEAAVDKAGSAAGRRSRAWIMAGVAAVALVAAAGGGWWAARSADDQ
CCCCCCCCCCCCCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCC
PAVAAAAVPRTPEEEIITETVEPAPPPAAAAAQGASSALAVPDPAPPGSAEAGTRSAAAS
CCCHHHCCCCCCHHHHHHHCCCCCCCCHHHHHCCCCCEEECCCCCCCCCCCCCCCHHHCC
APGATAAAASSPRNRPPVRKTAEAAVAAAPATPTASQAALAPAPPPKPAPRVIGPDEACA
CCCCHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
DAGFLARPMCIHQECQRPAVANHPLCVENRRRLEAEERRRLMQPQ
CCCHHHCCHHHHHHHCCCCCCCCCCCCCHHHCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8733241 [H]