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The map label for this gene is ushA [C]

Identifier: 120612659

GI number: 120612659

Start: 4469425

End: 4471350

Strand: Direct

Name: ushA [C]

Synonym: Aave_4022

Alternate gene names: 120612659

Gene position: 4469425-4471350 (Clockwise)

Preceding gene: 120612655

Following gene: 120612661

Centisome position: 83.5

GC content: 69.52

Gene sequence:

>1926_bases
ATGATGGCCGACGTGTGGAGAAGCAAGGGAAAGAACGTGCGCTGCCTCGCATGGCGCGCTGCCGCGGTGGCGGCGGCAGC
GCTGGCGGCGGCCTGCGGCGGCGGATCGGGTGGCGGCGAGCCGATGGAACTCACCATCCTGCACGTCAATGACCACCACT
CCACGCTGGAGTCGAAGTCCAGGACCCTGCAGCTCTCCACGGGCGGCTCCGCTCCGGTCGCCGTGGCCGTGGACGCGGGT
GGCTTCCCGCGCGTCACCGCGGCGATCGACGAACTTTCCAGGCGCGCGCCCAACGTGCTCAAGCTGCACGCGGGCGACGC
CCTGACCGGCACCCTGTATTTCAACCGCGCCGGTGCGGACGGCGAAGCCGACGCGGCCATGATGAACACCGTCTGCTTCG
ACGCCTTCACCCTCGGCAACCACGAATTCGACAAGGGCGACACGGGCCTCAAGAACTTCCTGGACCTGCTGCGCAAGGGC
AGCTGCAAGACGCCGGCCCTGAGCGCCAACGTGCGCTTCGGCGCCAGCTCCGCGCTCAATGCCGCCAAGGCCCCGGATGC
CGTCCAGGCTTCCACCATCGTCGAGCGCGGCGGCCAGAAAATCGGCATCGTCGGCCTCACCATCGCCGGCAAGACCAAGG
CCTCCTCCAGCCCCGACCCGGACACCACCTTCGAGGACGAAGCCACCGCCGCCCAGCGCGAGATCGACCGCCTGCGCGGC
CAGGGCATCAACAAGATCGTGCTGATGAGCCACATCGGCTACGACGCCGACCGCCAGATCGTGCCGAAGCTTTCCGGCGT
GGACGTGGTGGTGGGCGGCGACTCGCACACCCTGCTCGGCCCGGACGCGCTCAAGGCCACCGGCGTGGGCACGCCCGGCG
GTGCCTACCCGACGCGCACCACCGACAAGGACGGTCGCACCGTCTGCATCGTCCAGGCCTGGGAATACGCCCAGGTGGTG
GGCGAGCTGAAGGTGAACTTCGATGCCGACGGCAACGTCACCCAGTGCGCCGGCACCCCGCACGTGCTCATCGGCGACAA
CTTCACCATCGGCGGCAAGGCCCCGACGGATGCGGAAGCCAAGGCCCTGCAGGCCAGCGTGGCCGCCACCGGCTTCCTGC
GCGTGATCCAGCCCTCCGCCGCGGCCACCGCCACCCTGCAGCCCTTCAAGGACCGCGTGACCGTCTTCAACCGCACCCAG
GTCGCCGTGGCGCCCGAGGAACTGTGCTCCCGCCGCGTGCCCGGCGGCGCCGGCTCCACCGACTACAGCCGCTCCAGCGC
CGCCTGCAACGCCGAAGGCAGCGTGAGCGCGCGCGGCGGCGACATCCAGCAACTCGTCGCCCAGGCGTATCTCGACGTGG
CCAACGCACGTTACGGCGGCGCCGACATCTCGCTGCAAAGCGGCGGCGGCGTGCGCATCCCCCTGCAGGGCACCGTCTCG
GCCGCCCAGGTCATCCAGGTACTGCCCTTCGGCAACATGCTCTTCCGCCTGGACGTGACCGGCACGGAAGTGAAGGCCAT
GCTGGAAGACGGCATGGAAGCCGTCTTCGGCACCGGCGGCTCCACCGGCCCCTACCCCTACACCGGCGGCCTGCGCTTCG
ACGTGAATGCCGCCGCCGCGGCCGGCCAGCGCGTGTCCGGCATCGAAGTGCGCAACGCCGCCTCGGGCGCCTGGGAGCCG
CTCAATGCGACGAAGACGTACAAGCTCTTCGTGTTGAGCTTCAACGCCACGGGCGGCGATGGGTACAAGACGCTGGCGGC
CGTGCCTGCGGCGCGGCGGCTGGACATCGGCGTGCTGGATGCGGATGTGTTCTTCAGCTACATCGAAAAGCAGGGGAAGG
ACGGGACGACGGGGTTGCCGACGCTCAAGCGGTTGCCGCGGGACCTGTACAGCACGAAGACGTTCCAGGGACCGGCAGGA
AAGTAA

Upstream 100 bases:

>100_bases
AAATCGTGCCCAAACCACCCGCTCCGCCTCCCCATTCATCGTTCTGTCACGCCGCGCCGCAAGGATGCGGACTTTTGTCA
CAAGCAGTAAGGAGAGCGCC

Downstream 100 bases:

>100_bases
GGGAGAGCCCGGGGGACGGAGAGCTACGCATCACCGTTTTTCGAGGCGCCTCCGCCGAAGCAATACCGCAAAAACGCCTC
GCCCCCCGCCCCCAGCGTCC

Product: 5'-nucleotidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 641; Mature: 641

Protein sequence:

>641_residues
MMADVWRSKGKNVRCLAWRAAAVAAAALAAACGGGSGGGEPMELTILHVNDHHSTLESKSRTLQLSTGGSAPVAVAVDAG
GFPRVTAAIDELSRRAPNVLKLHAGDALTGTLYFNRAGADGEADAAMMNTVCFDAFTLGNHEFDKGDTGLKNFLDLLRKG
SCKTPALSANVRFGASSALNAAKAPDAVQASTIVERGGQKIGIVGLTIAGKTKASSSPDPDTTFEDEATAAQREIDRLRG
QGINKIVLMSHIGYDADRQIVPKLSGVDVVVGGDSHTLLGPDALKATGVGTPGGAYPTRTTDKDGRTVCIVQAWEYAQVV
GELKVNFDADGNVTQCAGTPHVLIGDNFTIGGKAPTDAEAKALQASVAATGFLRVIQPSAAATATLQPFKDRVTVFNRTQ
VAVAPEELCSRRVPGGAGSTDYSRSSAACNAEGSVSARGGDIQQLVAQAYLDVANARYGGADISLQSGGGVRIPLQGTVS
AAQVIQVLPFGNMLFRLDVTGTEVKAMLEDGMEAVFGTGGSTGPYPYTGGLRFDVNAAAAAGQRVSGIEVRNAASGAWEP
LNATKTYKLFVLSFNATGGDGYKTLAAVPAARRLDIGVLDADVFFSYIEKQGKDGTTGLPTLKRLPRDLYSTKTFQGPAG
K

Sequences:

>Translated_641_residues
MMADVWRSKGKNVRCLAWRAAAVAAAALAAACGGGSGGGEPMELTILHVNDHHSTLESKSRTLQLSTGGSAPVAVAVDAG
GFPRVTAAIDELSRRAPNVLKLHAGDALTGTLYFNRAGADGEADAAMMNTVCFDAFTLGNHEFDKGDTGLKNFLDLLRKG
SCKTPALSANVRFGASSALNAAKAPDAVQASTIVERGGQKIGIVGLTIAGKTKASSSPDPDTTFEDEATAAQREIDRLRG
QGINKIVLMSHIGYDADRQIVPKLSGVDVVVGGDSHTLLGPDALKATGVGTPGGAYPTRTTDKDGRTVCIVQAWEYAQVV
GELKVNFDADGNVTQCAGTPHVLIGDNFTIGGKAPTDAEAKALQASVAATGFLRVIQPSAAATATLQPFKDRVTVFNRTQ
VAVAPEELCSRRVPGGAGSTDYSRSSAACNAEGSVSARGGDIQQLVAQAYLDVANARYGGADISLQSGGGVRIPLQGTVS
AAQVIQVLPFGNMLFRLDVTGTEVKAMLEDGMEAVFGTGGSTGPYPYTGGLRFDVNAAAAAGQRVSGIEVRNAASGAWEP
LNATKTYKLFVLSFNATGGDGYKTLAAVPAARRLDIGVLDADVFFSYIEKQGKDGTTGLPTLKRLPRDLYSTKTFQGPAG
K
>Mature_641_residues
MMADVWRSKGKNVRCLAWRAAAVAAAALAAACGGGSGGGEPMELTILHVNDHHSTLESKSRTLQLSTGGSAPVAVAVDAG
GFPRVTAAIDELSRRAPNVLKLHAGDALTGTLYFNRAGADGEADAAMMNTVCFDAFTLGNHEFDKGDTGLKNFLDLLRKG
SCKTPALSANVRFGASSALNAAKAPDAVQASTIVERGGQKIGIVGLTIAGKTKASSSPDPDTTFEDEATAAQREIDRLRG
QGINKIVLMSHIGYDADRQIVPKLSGVDVVVGGDSHTLLGPDALKATGVGTPGGAYPTRTTDKDGRTVCIVQAWEYAQVV
GELKVNFDADGNVTQCAGTPHVLIGDNFTIGGKAPTDAEAKALQASVAATGFLRVIQPSAAATATLQPFKDRVTVFNRTQ
VAVAPEELCSRRVPGGAGSTDYSRSSAACNAEGSVSARGGDIQQLVAQAYLDVANARYGGADISLQSGGGVRIPLQGTVS
AAQVIQVLPFGNMLFRLDVTGTEVKAMLEDGMEAVFGTGGSTGPYPYTGGLRFDVNAAAAAGQRVSGIEVRNAASGAWEP
LNATKTYKLFVLSFNATGGDGYKTLAAVPAARRLDIGVLDADVFFSYIEKQGKDGTTGLPTLKRLPRDLYSTKTFQGPAG
K

Specific function: Degradation Of External Udp-Glucose To Uridine Monophosphate And Glucose-1-Phosphate, Which Can Then Be Used By The Cell. [C]

COG id: COG0737

COG function: function code F; 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5'-nucleotidase family [H]

Homologues:

Organism=Homo sapiens, GI4505467, Length=611, Percent_Identity=31.5875613747954, Blast_Score=206, Evalue=7e-53,
Organism=Escherichia coli, GI1786687, Length=590, Percent_Identity=26.1016949152542, Blast_Score=117, Evalue=3e-27,
Organism=Drosophila melanogaster, GI19922446, Length=579, Percent_Identity=29.0155440414508, Blast_Score=189, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24654424, Length=579, Percent_Identity=29.0155440414508, Blast_Score=189, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24641187, Length=606, Percent_Identity=27.3927392739274, Blast_Score=188, Evalue=1e-47,
Organism=Drosophila melanogaster, GI28573524, Length=558, Percent_Identity=29.2114695340502, Blast_Score=180, Evalue=3e-45,
Organism=Drosophila melanogaster, GI19922444, Length=574, Percent_Identity=29.0940766550523, Blast_Score=176, Evalue=4e-44,
Organism=Drosophila melanogaster, GI221329836, Length=460, Percent_Identity=28.4782608695652, Blast_Score=152, Evalue=9e-37,
Organism=Drosophila melanogaster, GI161076508, Length=242, Percent_Identity=28.5123966942149, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24652512, Length=242, Percent_Identity=28.5123966942149, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI19921980, Length=242, Percent_Identity=28.5123966942149, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008334
- InterPro:   IPR006146
- InterPro:   IPR006179
- InterPro:   IPR004843
- InterPro:   IPR006420 [H]

Pfam domain/function: PF02872 5_nucleotid_C; PF00149 Metallophos [H]

EC number: =3.1.3.5 [H]

Molecular weight: Translated: 66301; Mature: 66301

Theoretical pI: Translated: 7.47; Mature: 7.47

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00786 5_NUCLEOTIDASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMADVWRSKGKNVRCLAWRAAAVAAAALAAACGGGSGGGEPMELTILHVNDHHSTLESKS
CCCHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCHHHHHCCC
RTLQLSTGGSAPVAVAVDAGGFPRVTAAIDELSRRAPNVLKLHAGDALTGTLYFNRAGAD
CEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCEEEEEEEEEECCCC
GEADAAMMNTVCFDAFTLGNHEFDKGDTGLKNFLDLLRKGSCKTPALSANVRFGASSALN
CCCHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCEECEEEECCHHHCC
AAKAPDAVQASTIVERGGQKIGIVGLTIAGKTKASSSPDPDTTFEDEATAAQREIDRLRG
CCCCCCHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
QGINKIVLMSHIGYDADRQIVPKLSGVDVVVGGDSHTLLGPDALKATGVGTPGGAYPTRT
CCCCEEEEEEECCCCCCCHHCCCCCCCEEEECCCCCEEECCCHHHCCCCCCCCCCCCCCC
TDKDGRTVCIVQAWEYAQVVGELKVNFDADGNVTQCAGTPHVLIGDNFTIGGKAPTDAEA
CCCCCCEEEEEECCHHHHHHEEEEEEECCCCCEEEECCCCEEEECCCEEECCCCCCCHHH
KALQASVAATGFLRVIQPSAAATATLQPFKDRVTVFNRTQVAVAPEELCSRRVPGGAGST
HHHHHHHHHHHHHEEECCCCCCEEECCCCCCCEEEEECEEEEECHHHHHHCCCCCCCCCC
DYSRSSAACNAEGSVSARGGDIQQLVAQAYLDVANARYGGADISLQSGGGVRIPLQGTVS
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEECCCCC
AAQVIQVLPFGNMLFRLDVTGTEVKAMLEDGMEAVFGTGGSTGPYPYTGGLRFDVNAAAA
HHHHHHHCCCCCEEEEEECCCHHHHHHHHHCHHHEECCCCCCCCCCCCCCEEEECCHHHH
AGQRVSGIEVRNAASGAWEPLNATKTYKLFVLSFNATGGDGYKTLAAVPAARRLDIGVLD
CCCCCCCEEEECCCCCCCCCCCCCCEEEEEEEEEECCCCCCCHHHHHCCCCCCCEEEEEC
ADVFFSYIEKQGKDGTTGLPTLKRLPRDLYSTKTFQGPAGK
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MMADVWRSKGKNVRCLAWRAAAVAAAALAAACGGGSGGGEPMELTILHVNDHHSTLESKS
CCCHHHHHCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCHHHHHCCC
RTLQLSTGGSAPVAVAVDAGGFPRVTAAIDELSRRAPNVLKLHAGDALTGTLYFNRAGAD
CEEEEECCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEEEECCCEEEEEEEEEECCCC
GEADAAMMNTVCFDAFTLGNHEFDKGDTGLKNFLDLLRKGSCKTPALSANVRFGASSALN
CCCHHHHHHHHHHHEEECCCCCCCCCCCCHHHHHHHHHCCCCCCCCEECEEEECCHHHCC
AAKAPDAVQASTIVERGGQKIGIVGLTIAGKTKASSSPDPDTTFEDEATAAQREIDRLRG
CCCCCCHHHHHHHHHCCCCEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
QGINKIVLMSHIGYDADRQIVPKLSGVDVVVGGDSHTLLGPDALKATGVGTPGGAYPTRT
CCCCEEEEEEECCCCCCCHHCCCCCCCEEEECCCCCEEECCCHHHCCCCCCCCCCCCCCC
TDKDGRTVCIVQAWEYAQVVGELKVNFDADGNVTQCAGTPHVLIGDNFTIGGKAPTDAEA
CCCCCCEEEEEECCHHHHHHEEEEEEECCCCCEEEECCCCEEEECCCEEECCCCCCCHHH
KALQASVAATGFLRVIQPSAAATATLQPFKDRVTVFNRTQVAVAPEELCSRRVPGGAGST
HHHHHHHHHHHHHEEECCCCCCEEECCCCCCCEEEEECEEEEECHHHHHHCCCCCCCCCC
DYSRSSAACNAEGSVSARGGDIQQLVAQAYLDVANARYGGADISLQSGGGVRIPLQGTVS
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCEEEEECCCCC
AAQVIQVLPFGNMLFRLDVTGTEVKAMLEDGMEAVFGTGGSTGPYPYTGGLRFDVNAAAA
HHHHHHHCCCCCEEEEEECCCHHHHHHHHHCHHHEECCCCCCCCCCCCCCEEEECCHHHH
AGQRVSGIEVRNAASGAWEPLNATKTYKLFVLSFNATGGDGYKTLAAVPAARRLDIGVLD
CCCCCCCEEEECCCCCCCCCCCCCCEEEEEEEEEECCCCCCCHHHHHCCCCCCCEEEEEC
ADVFFSYIEKQGKDGTTGLPTLKRLPRDLYSTKTFQGPAGK
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]