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The map label for this gene is katE [H]

Identifier: 120612629

GI number: 120612629

Start: 4425027

End: 4427168

Strand: Direct

Name: katE [H]

Synonym: Aave_3991

Alternate gene names: 120612629

Gene position: 4425027-4427168 (Clockwise)

Preceding gene: 120612627

Following gene: 120612630

Centisome position: 82.67

GC content: 69.79

Gene sequence:

>2142_bases
ATGCCCAAGAACACCCTCTCCCCCAGCGACTCCGCCGGAAAGAAGGCACCGCACAAGGTGCAGGCCGCCTCCGCCGCGGC
CACCGGCGACACCGCGCGCGGCCAGGGCGGAGAACTGCAGCAGCAGGCCGGCGGCGGCCACCCGGTGCTCACCACGCAGC
AGGGCATCCCCGTTGCGGACAACCAGAACTCGCTGCGCCCCACGCCGCGCGGGCCCACGCTGCTCGAGGATTTCATCCTG
CGCGAGAAGATCACGCATTTCGACCACGAGCGCATTCCCGAGCGCATCGTGCATGCGCGCGGCAACGCGGCGCACGGCGT
GTTCGAACTCACGGAAAGCCTGGAAAAGTACACCACCGCGCGCATCCTCACCGAGGTCGGCAGGCAGACGCCCGTGTTCT
GCCGCTTCTCCACGGTGGCGGGCGGCGCGGGCTCGGTGGACACGCCGCGCGACGTGCGCGGCTTCGCCGTGAAGTTCTAC
ACCGGCGAAGGCAACTGGGACCTGGTGGGCAACAACATCCCCGTGTTCTTCATCCAGGACGCGATGAAGTTCCCCGACCT
CGTCCACGCCGTGAAGATGGAACCGGACCGCGCGTTCCCCCAGGCCGCGAGCGCGCACGACACGTTCTGGGATTTCATCT
CGCTCATGCCCGAGAGCCTGCACATGATCATGTGGGCGATGAGCGACCGCACCATCCCGCGCAGCCTGCGCACGATGGAA
GGCTTCGGCGTGCATTCCTTCCGCCTGCTCGACGCGCAGGGCGGGAGCACGTTCGTGAAGTTCCACTGGCGCCCGCGCCT
GGGCATCCAATCGACCGTGTGGGACGAGGCGGTGAAGTTGCAGAGCGCCGACAACGATTTCCACCGGCGCGACCTGTTCG
AGGCGATCCAGGCGGGCGACTTTCCCGAATGGGACCTGGCCGTGCAGCTCTTCACCGAGGAAGAGGCCGCGCGCTTCCCG
TTCGACCACCTCGACCCGACCAAGCTGGTGCCGGAAGAACTCGTGCCCCTGAAGACCATCGGCCGCATGACCCTGAACCG
CTGGCCCGACAACTTCTTCGCCGAAACCGAGCAGGTGGCCTTCTGCCCCGCCAACGTGCCGCCGGGCATCGATTTCTCGA
ACGACCCGCTGCTGCAGGGACGCCTCTTCTCGTACCTGGACACGCAGCTCTCGCGCCTGGGCAGCCCGAACTTCGTGCAG
ATCCCGATCAACGCGCCCAAGTGCCCGTTCCACAACATGCAGCGCGACGGCCACATGCAGATGCAGGTGCCCAAGGGCCG
CGTGGCCTATGAGCCGAGCAGCCTGCAGCAGGACACGCCGCGCGCCTCCGTGGCCCAGGGATTCCGTCATTTCGCCGAGC
GCCTGGCCGGCGACGACGGCGCCAAGGGCCGCCTGCGGCCGGAGAGCTTCGCCGACCACTACAGCCAGGCCCGCCTGTTC
TACCGCAGCCAGAGCGCCATCGAGCAGGCGCACATGGCCTCCGCGCTGGTGTTCGAGCTGTCCAAGGTGGAGACCGAGCG
CGTGCGCGTCGCCGTCGTCGCCCAGTTGCTGAACGTGGACGAGGGCCTGGCCCAGCGGGTCGCGGACGGCCTCGGCCTGC
CGGAACTGCCTGCGCCCTTCCCGGCCGCGGCGCCCGCGCAGGACCTGCCGCTGTCGCCCGCGCTGCGCATCATCGACCGC
ATGAAGCCCACGCTGCAGGGCCGCTGCATCGGCATCCTGGTGGCCGACGGATCCGCGCCGGAGGCGATCGCCGCGCTGCG
CAAGGCGGCCGAGAAGGCCGGCGCGAAGGTGAAGATCGTGGCGCCCAAGGTCGGCGGCGCCGTACTGTCCGACGGATCGC
GGCTGCCGGCCGATGGCCAGCTCGCGGGCACGCCGTCGGTGGTGTTCGACGCGGTGGCCTCCGTGCTCGCTCCCCAGGCC
GGCGCACGGCTCGCCCGCGAAGCCGCGGCGGTGGACTGGTTCCGCGACGCCTACGGCCACCTCAAGGCGATCGCCGCCTG
CAAGGGTTCCCAGCCCATTCTGGCGGCCGCCGGCATCGAGCCGGACGCCGGCGTGCTGGCCCCGGACGACGTCTCCGCCT
TCATCGATGCGGCCGCGACCCGCCAGTGGGAACGCGAACCCAAGGTACGGATGCTGGCATGA

Upstream 100 bases:

>100_bases
TCCCCAGCCAAAGCGCGCTTGTCCTACAGCCCCGTTCCCCATGGCGGAAAAAGATGCCGTTTTCCGCGACCAGCGGCCCA
CTTCCCACAAGGAACGCCCC

Downstream 100 bases:

>100_bases
TCCAGTCCCCCGCGCCGGCCCATGCCACCGATTTCCTCCGACCTTCCACCCCCGAACCCCTCCAAGGGACAGACCACTCC
ATGACCCCGCTGCGTATCCT

Product: catalase

Products: NA

Alternate protein names: KAT2 [H]

Number of amino acids: Translated: 713; Mature: 712

Protein sequence:

>713_residues
MPKNTLSPSDSAGKKAPHKVQAASAAATGDTARGQGGELQQQAGGGHPVLTTQQGIPVADNQNSLRPTPRGPTLLEDFIL
REKITHFDHERIPERIVHARGNAAHGVFELTESLEKYTTARILTEVGRQTPVFCRFSTVAGGAGSVDTPRDVRGFAVKFY
TGEGNWDLVGNNIPVFFIQDAMKFPDLVHAVKMEPDRAFPQAASAHDTFWDFISLMPESLHMIMWAMSDRTIPRSLRTME
GFGVHSFRLLDAQGGSTFVKFHWRPRLGIQSTVWDEAVKLQSADNDFHRRDLFEAIQAGDFPEWDLAVQLFTEEEAARFP
FDHLDPTKLVPEELVPLKTIGRMTLNRWPDNFFAETEQVAFCPANVPPGIDFSNDPLLQGRLFSYLDTQLSRLGSPNFVQ
IPINAPKCPFHNMQRDGHMQMQVPKGRVAYEPSSLQQDTPRASVAQGFRHFAERLAGDDGAKGRLRPESFADHYSQARLF
YRSQSAIEQAHMASALVFELSKVETERVRVAVVAQLLNVDEGLAQRVADGLGLPELPAPFPAAAPAQDLPLSPALRIIDR
MKPTLQGRCIGILVADGSAPEAIAALRKAAEKAGAKVKIVAPKVGGAVLSDGSRLPADGQLAGTPSVVFDAVASVLAPQA
GARLAREAAAVDWFRDAYGHLKAIAACKGSQPILAAAGIEPDAGVLAPDDVSAFIDAAATRQWEREPKVRMLA

Sequences:

>Translated_713_residues
MPKNTLSPSDSAGKKAPHKVQAASAAATGDTARGQGGELQQQAGGGHPVLTTQQGIPVADNQNSLRPTPRGPTLLEDFIL
REKITHFDHERIPERIVHARGNAAHGVFELTESLEKYTTARILTEVGRQTPVFCRFSTVAGGAGSVDTPRDVRGFAVKFY
TGEGNWDLVGNNIPVFFIQDAMKFPDLVHAVKMEPDRAFPQAASAHDTFWDFISLMPESLHMIMWAMSDRTIPRSLRTME
GFGVHSFRLLDAQGGSTFVKFHWRPRLGIQSTVWDEAVKLQSADNDFHRRDLFEAIQAGDFPEWDLAVQLFTEEEAARFP
FDHLDPTKLVPEELVPLKTIGRMTLNRWPDNFFAETEQVAFCPANVPPGIDFSNDPLLQGRLFSYLDTQLSRLGSPNFVQ
IPINAPKCPFHNMQRDGHMQMQVPKGRVAYEPSSLQQDTPRASVAQGFRHFAERLAGDDGAKGRLRPESFADHYSQARLF
YRSQSAIEQAHMASALVFELSKVETERVRVAVVAQLLNVDEGLAQRVADGLGLPELPAPFPAAAPAQDLPLSPALRIIDR
MKPTLQGRCIGILVADGSAPEAIAALRKAAEKAGAKVKIVAPKVGGAVLSDGSRLPADGQLAGTPSVVFDAVASVLAPQA
GARLAREAAAVDWFRDAYGHLKAIAACKGSQPILAAAGIEPDAGVLAPDDVSAFIDAAATRQWEREPKVRMLA
>Mature_712_residues
PKNTLSPSDSAGKKAPHKVQAASAAATGDTARGQGGELQQQAGGGHPVLTTQQGIPVADNQNSLRPTPRGPTLLEDFILR
EKITHFDHERIPERIVHARGNAAHGVFELTESLEKYTTARILTEVGRQTPVFCRFSTVAGGAGSVDTPRDVRGFAVKFYT
GEGNWDLVGNNIPVFFIQDAMKFPDLVHAVKMEPDRAFPQAASAHDTFWDFISLMPESLHMIMWAMSDRTIPRSLRTMEG
FGVHSFRLLDAQGGSTFVKFHWRPRLGIQSTVWDEAVKLQSADNDFHRRDLFEAIQAGDFPEWDLAVQLFTEEEAARFPF
DHLDPTKLVPEELVPLKTIGRMTLNRWPDNFFAETEQVAFCPANVPPGIDFSNDPLLQGRLFSYLDTQLSRLGSPNFVQI
PINAPKCPFHNMQRDGHMQMQVPKGRVAYEPSSLQQDTPRASVAQGFRHFAERLAGDDGAKGRLRPESFADHYSQARLFY
RSQSAIEQAHMASALVFELSKVETERVRVAVVAQLLNVDEGLAQRVADGLGLPELPAPFPAAAPAQDLPLSPALRIIDRM
KPTLQGRCIGILVADGSAPEAIAALRKAAEKAGAKVKIVAPKVGGAVLSDGSRLPADGQLAGTPSVVFDAVASVLAPQAG
ARLAREAAAVDWFRDAYGHLKAIAACKGSQPILAAAGIEPDAGVLAPDDVSAFIDAAATRQWEREPKVRMLA

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. Could protect cells in nodules which have a high potential to produce hydrogen peroxide because of the strong reducing conditions requ

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family. HPII subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=401, Percent_Identity=47.1321695760599, Blast_Score=382, Evalue=1e-106,
Organism=Escherichia coli, GI48994891, Length=683, Percent_Identity=51.8301610541728, Blast_Score=670, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71998444, Length=400, Percent_Identity=45.75, Blast_Score=380, Evalue=1e-105,
Organism=Caenorhabditis elegans, GI25147792, Length=438, Percent_Identity=44.0639269406393, Blast_Score=375, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI25151141, Length=438, Percent_Identity=44.0639269406393, Blast_Score=375, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6320462, Length=403, Percent_Identity=40.1985111662531, Blast_Score=305, Evalue=1e-83,
Organism=Saccharomyces cerevisiae, GI6321525, Length=546, Percent_Identity=34.981684981685, Blast_Score=296, Evalue=1e-80,
Organism=Drosophila melanogaster, GI17981717, Length=397, Percent_Identity=44.8362720403023, Blast_Score=351, Evalue=1e-96,
Organism=Drosophila melanogaster, GI19920968, Length=420, Percent_Identity=41.1904761904762, Blast_Score=333, Evalue=3e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 77631; Mature: 77500

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: PS00437 CATALASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKNTLSPSDSAGKKAPHKVQAASAAATGDTARGQGGELQQQAGGGHPVLTTQQGIPVAD
CCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCEEECCCCCCCCC
NQNSLRPTPRGPTLLEDFILREKITHFDHERIPERIVHARGNAAHGVFELTESLEKYTTA
CCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
RILTEVGRQTPVFCRFSTVAGGAGSVDTPRDVRGFAVKFYTGEGNWDLVGNNIPVFFIQD
HHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEEEECCCCEEEECCCCCEEEECC
AMKFPDLVHAVKMEPDRAFPQAASAHDTFWDFISLMPESLHMIMWAMSDRTIPRSLRTME
HHCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
GFGVHSFRLLDAQGGSTFVKFHWRPRLGIQSTVWDEAVKLQSADNDFHRRDLFEAIQAGD
CCCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
FPEWDLAVQLFTEEEAARFPFDHLDPTKLVPEELVPLKTIGRMTLNRWPDNFFAETEQVA
CCCCCEEEEEEECHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCHHHCCCCCEE
FCPANVPPGIDFSNDPLLQGRLFSYLDTQLSRLGSPNFVQIPINAPKCPFHNMQRDGHMQ
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCEE
MQVPKGRVAYEPSSLQQDTPRASVAQGFRHFAERLAGDDGAKGRLRPESFADHYSQARLF
EECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
YRSQSAIEQAHMASALVFELSKVETERVRVAVVAQLLNVDEGLAQRVADGLGLPELPAPF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCC
PAAAPAQDLPLSPALRIIDRMKPTLQGRCIGILVADGSAPEAIAALRKAAEKAGAKVKIV
CCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCEEEEE
APKVGGAVLSDGSRLPADGQLAGTPSVVFDAVASVLAPQAGARLAREAAAVDWFRDAYGH
CCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LKAIAACKGSQPILAAAGIEPDAGVLAPDDVSAFIDAAATRQWEREPKVRMLA
HHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEECC
>Mature Secondary Structure 
PKNTLSPSDSAGKKAPHKVQAASAAATGDTARGQGGELQQQAGGGHPVLTTQQGIPVAD
CCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCEEECCCCCCCCC
NQNSLRPTPRGPTLLEDFILREKITHFDHERIPERIVHARGNAAHGVFELTESLEKYTTA
CCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHH
RILTEVGRQTPVFCRFSTVAGGAGSVDTPRDVRGFAVKFYTGEGNWDLVGNNIPVFFIQD
HHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEEEECCCCEEEECCCCCEEEECC
AMKFPDLVHAVKMEPDRAFPQAASAHDTFWDFISLMPESLHMIMWAMSDRTIPRSLRTME
HHCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
GFGVHSFRLLDAQGGSTFVKFHWRPRLGIQSTVWDEAVKLQSADNDFHRRDLFEAIQAGD
CCCCCEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
FPEWDLAVQLFTEEEAARFPFDHLDPTKLVPEELVPLKTIGRMTLNRWPDNFFAETEQVA
CCCCCEEEEEEECHHHHHCCCCCCCCCCCCHHHHCCHHHHHHHHHHCCCCHHHCCCCCEE
FCPANVPPGIDFSNDPLLQGRLFSYLDTQLSRLGSPNFVQIPINAPKCPFHNMQRDGHMQ
EECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCEE
MQVPKGRVAYEPSSLQQDTPRASVAQGFRHFAERLAGDDGAKGRLRPESFADHYSQARLF
EECCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
YRSQSAIEQAHMASALVFELSKVETERVRVAVVAQLLNVDEGLAQRVADGLGLPELPAPF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCC
PAAAPAQDLPLSPALRIIDRMKPTLQGRCIGILVADGSAPEAIAALRKAAEKAGAKVKIV
CCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCCCEEEEE
APKVGGAVLSDGSRLPADGQLAGTPSVVFDAVASVLAPQAGARLAREAAAVDWFRDAYGH
CCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
LKAIAACKGSQPILAAAGIEPDAGVLAPDDVSAFIDAAATRQWEREPKVRMLA
HHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10198032; 11481431 [H]