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The map label for this gene is gbpR [H]

Identifier: 120612622

GI number: 120612622

Start: 4416316

End: 4417308

Strand: Reverse

Name: gbpR [H]

Synonym: Aave_3983

Alternate gene names: 120612622

Gene position: 4417308-4416316 (Counterclockwise)

Preceding gene: 120612625

Following gene: 120612618

Centisome position: 82.52

GC content: 73.11

Gene sequence:

>993_bases
ATGGACGCCACCACAGGCCGCCTCGTGCGCAAGCTCCGGCTGCGCCATCTGGAACTGCTCGCCGTGCTCGCCGGGGCGGA
CACCATGCGCAGCGCGTCCGCGCGGCTGCACCTGAGCCAGCCCGCCATCAGCAAGATGCTCGGCGAGATCGAGGCCTGTT
TCGGCGCGCGCCTGTTCGAGCGCAACCACCAGGGCATCCATCCGAATGCGCTGGGCGCCGGGGCGGTCTTCCACGCCCGG
GCGGTGCTGAACCAGCTGGCGCGCGCCACCGAGGACGTCGGCGCGATGCAGCAGGGCGCGCACGCCGTGCTGCGCGTGGG
CGCTCCCTCCGTCACAGCCACCGTGCCGACGGCGGTCGCGCGGCTGCGCGAGCGCATGCCCGGCGCCACGGTGCAGATCC
GCGAGGGCCGGGTGCAGGAGCTGATCCAGCGCCTGCTGGAAGGCGAACTCGACTGCGTGTACGGCGCCGTGACGCCCGAG
CTCATCACCGCCGACATCACGCCGATGCTGGAGCCCGTCGCGATGCTGCGCGACGAGCTGTGCGTGCTGGCGTCGGTGCC
GCGCCAGGGGGCCGGCGCGGGCCATCGGCGGCTGCGGTGGCGAGACCTGGGCCATGCTCCGTGGCTGCTGCCGCCGAAGG
AAACACTGGTGCGCCAGGCCTTCGTGACCGCCTTCCTGAATGACGGCGCGACGCCGCCGGTGCCGGTGATCGAGGCGATC
TCGTCCGTGACCATCGGCGCGCTGATGCGCCAGGATCCGTCGCTGCTGTGCGCGGTGCGGCTGGAGCATGCCGTGGACGA
GATCGGGCGTGGCGGGGTGCTGCGGCTCGATGTCGCGCCCAAGGTGCCGTTGCCCTCCTTCGGGCTTTTCTTCCGACGGG
ACGGCATGGAACGGCCGCCCGTGCTGCTGGTCTTCGCCGACGCGGTGAAGGCCGTCGCCGCGCGCCTCGGCATGCGGCAA
CGCGGTGCCCGGGGCGGCGCGGGCGCTCGTTGA

Upstream 100 bases:

>100_bases
TTGAATGGGCATGGGCGGACCTTATCGCCGCCAGCGATTCTTGAAAATTCGATAATCGTGATGGAGTGATCACGGTATGG
AATCGAGACAAGGAACGTCC

Downstream 100 bases:

>100_bases
CCTCCGGGCGGCGCCGGCCGGCTTGTCCGGGTTTTACTTGACCGGGATCGGCGTGGAGCGGTCCACCGGCACGGCCGTCA
CGGCGTTCTGCGGCGAGCCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MDATTGRLVRKLRLRHLELLAVLAGADTMRSASARLHLSQPAISKMLGEIEACFGARLFERNHQGIHPNALGAGAVFHAR
AVLNQLARATEDVGAMQQGAHAVLRVGAPSVTATVPTAVARLRERMPGATVQIREGRVQELIQRLLEGELDCVYGAVTPE
LITADITPMLEPVAMLRDELCVLASVPRQGAGAGHRRLRWRDLGHAPWLLPPKETLVRQAFVTAFLNDGATPPVPVIEAI
SSVTIGALMRQDPSLLCAVRLEHAVDEIGRGGVLRLDVAPKVPLPSFGLFFRRDGMERPPVLLVFADAVKAVAARLGMRQ
RGARGGAGAR

Sequences:

>Translated_330_residues
MDATTGRLVRKLRLRHLELLAVLAGADTMRSASARLHLSQPAISKMLGEIEACFGARLFERNHQGIHPNALGAGAVFHAR
AVLNQLARATEDVGAMQQGAHAVLRVGAPSVTATVPTAVARLRERMPGATVQIREGRVQELIQRLLEGELDCVYGAVTPE
LITADITPMLEPVAMLRDELCVLASVPRQGAGAGHRRLRWRDLGHAPWLLPPKETLVRQAFVTAFLNDGATPPVPVIEAI
SSVTIGALMRQDPSLLCAVRLEHAVDEIGRGGVLRLDVAPKVPLPSFGLFFRRDGMERPPVLLVFADAVKAVAARLGMRQ
RGARGGAGAR
>Mature_330_residues
MDATTGRLVRKLRLRHLELLAVLAGADTMRSASARLHLSQPAISKMLGEIEACFGARLFERNHQGIHPNALGAGAVFHAR
AVLNQLARATEDVGAMQQGAHAVLRVGAPSVTATVPTAVARLRERMPGATVQIREGRVQELIQRLLEGELDCVYGAVTPE
LITADITPMLEPVAMLRDELCVLASVPRQGAGAGHRRLRWRDLGHAPWLLPPKETLVRQAFVTAFLNDGATPPVPVIEAI
SSVTIGALMRQDPSLLCAVRLEHAVDEIGRGGVLRLDVAPKVPLPSFGLFFRRDGMERPPVLLVFADAVKAVAARLGMRQ
RGARGGAGAR

Specific function: Does not seem to be required for sbpA expression [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=294, Percent_Identity=26.1904761904762, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI87081904, Length=157, Percent_Identity=33.1210191082803, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1789506, Length=239, Percent_Identity=22.1757322175732, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1787879, Length=146, Percent_Identity=30.8219178082192, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35465; Mature: 35465

Theoretical pI: Translated: 10.99; Mature: 10.99

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDATTGRLVRKLRLRHLELLAVLAGADTMRSASARLHLSQPAISKMLGEIEACFGARLFE
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHH
RNHQGIHPNALGAGAVFHARAVLNQLARATEDVGAMQQGAHAVLRVGAPSVTATVPTAVA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCHHHHHHHHHH
RLRERMPGATVQIREGRVQELIQRLLEGELDCVYGAVTPELITADITPMLEPVAMLRDEL
HHHHHCCCCEEEECCCHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHH
CVLASVPRQGAGAGHRRLRWRDLGHAPWLLPPKETLVRQAFVTAFLNDGATPPVPVIEAI
HHHHHCCCCCCCCCHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHH
SSVTIGALMRQDPSLLCAVRLEHAVDEIGRGGVLRLDVAPKVPLPSFGLFFRRDGMERPP
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHCCCCCCC
VLLVFADAVKAVAARLGMRQRGARGGAGAR
EEEEHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MDATTGRLVRKLRLRHLELLAVLAGADTMRSASARLHLSQPAISKMLGEIEACFGARLFE
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHEEECCHHHHHHHHHHHHHHHHHHHH
RNHQGIHPNALGAGAVFHARAVLNQLARATEDVGAMQQGAHAVLRVGAPSVTATVPTAVA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEEECCCCHHHHHHHHHH
RLRERMPGATVQIREGRVQELIQRLLEGELDCVYGAVTPELITADITPMLEPVAMLRDEL
HHHHHCCCCEEEECCCHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHH
CVLASVPRQGAGAGHRRLRWRDLGHAPWLLPPKETLVRQAFVTAFLNDGATPPVPVIEAI
HHHHHCCCCCCCCCHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHH
SSVTIGALMRQDPSLLCAVRLEHAVDEIGRGGVLRLDVAPKVPLPSFGLFFRRDGMERPP
HHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHCCCCCCC
VLLVFADAVKAVAARLGMRQRGARGGAGAR
EEEEHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]