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The map label for this gene is tcp [H]

Identifier: 120612520

GI number: 120612520

Start: 4303253

End: 4304926

Strand: Direct

Name: tcp [H]

Synonym: Aave_3880

Alternate gene names: 120612520

Gene position: 4303253-4304926 (Clockwise)

Preceding gene: 120612519

Following gene: 120612522

Centisome position: 80.39

GC content: 69.24

Gene sequence:

>1674_bases
ATGATGACCCTCGATAACTGGATGATGCGCACCAAACTGCTGGCCGGCTTCGGCCTCGTGCTGGTCATCGCCTGTATCGT
CAGCCTGCTGGGCGTTGCCAACCTGTCCAGCATGAACGACCGCTCCACCGAGATATCCCGGAAGTCCCTGCCAAGCGTGG
CGGCCTCGGGAACGATCAGCAGGAATCTGTCTGCCCTGCGCATCGCCCGCCTGGGCCTGATCCTCACGGGGCCCAATTCG
CCCATGCCGCAGGCGATCGCCGCGGTGGAAAGCGCCAGCACGGCGCTCAATGCCTCCGTCGAGGCCGCAGCCCCGCTCTT
CACCAGCGCCGAAGAACGACCGCTCTACGAGGAGCTGCGCAATCAGGTCGCGGCCTACAGCTCGACACTGCCGCAGCAAC
TGCAGCACGCAAGGAACAACGACATCGACGCGGTGCGCGCGATCTTCGTGGGCCCGGCAGCCGTGGCCTACCGGGCCGCC
AACAAGGCGCTCGACGACCTGATCGCCATCAACAACAAGGGCAGCGATCTCGCCGCCGAACGCGCCGCGGCCACCTACAG
GGAAGGCCGCGTGCAACTCGCGGCCGGACTGGTGGCGATGATCGCGCTCAGCGCCGTGATCGCCGTCCTGCTGGCGGGCA
ACCTGTCGCGCCGGTCCCGGCAGGGCATGGACGCGGCCCTGCGCATGGCCCGCGGCGAACTCGGCCATCCCCTTGCGACC
AGCGGGAAGGACGAGCTCGCGCAGATGATGCAGGCGCTCGAGGCGACCCGCGAACACTTGCGGACGACCGTGGGCAATGT
GCGTCAGAACGCGGAAGCCGTGGCGACGGCGAGCGCGGAGATATCCCAGGGCAACCAGGACCTCAGCGGCCGCACCGAGA
GCCAGGCGAGCGCGCTGGAGCAGACGGCCGCCTCCATGGAAGAGCTGGGCACCACCGTGCAGCAGAACGCCGACAGCGCG
CGCCAGGCCAACCAGCTCGCCAAGAATGCGGCCATGGTCGCGGTGCAGGGCGGCGAGGTCGTGGGCCAGGTCGTGGAAAC
CATGAAGGGCATCAACGAGTCGTCCCGGCAGATCGCGGACATCATCCAGGTGATCGACGGCATCGCCTTCCAGACCAACA
TCCTGGCACTGAACGCGGCCGTGGAAGCCGCCCGGGCCGGCGAGCAGGGCCGGGGCTTCGCCGTGGTGGCCAGCGAGGTG
CGCAGCCTGGCGGGCCGCTCCGCCGACGCGGCCAAGGAGATCAAGAACCTCATCGGGGCCAGCGTGGAGCGCGTGGCGGC
CGGCAACGCGCTGGTGGACCAGGCCGGTGCCACCATGCAGGAGATCGTCGGCGCCATCAACCGCGTGACGGACATCATGG
GCGAGATCAGCGCCGCCAGCGTGGAGCAGGCATCGGGCGTGAGCCAAGTAGGCGAGGCCGTGACGCAGATGGACCGGGCG
ACACAGCAGAACGCCGCGCTGGTCGAGGAAATGGCCGCGGCGGCCGGCAGCCTCAAGAAGCAGGCCGAGGATCTGGTGCG
CGGAGTGGCGACGTTCCAGCTCGGCGATGGCCGGCTGGCCATGTCTTCCGCCGCCTCCGCTTCCTCCGGTCCCATGGAGT
TACGCCGTCCCGTGGCGCTGTCCAGCCAGTCCGGCCCTGCTCTGGCGCTGGCCGCGGCCGGCACGGCTTCGTGA

Upstream 100 bases:

>100_bases
TACATACGATTACATCCAGAGCGCTTCCAGACACATAACAACCCCAGCGCCTCCCCCATATCCGCCCCTGCTCCGGCGGC
GTTTCCCCCTTTGAAAGACC

Downstream 100 bases:

>100_bases
AATCGTGGGCGACGCGCGGGGCACCCTGCTCGCAGGCCAATCGATATTTTCAAACCTGCCGCGAATGGTGCCGCCATTAC
CACCGCGGTTTTGAATCACC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 557; Mature: 557

Protein sequence:

>557_residues
MMTLDNWMMRTKLLAGFGLVLVIACIVSLLGVANLSSMNDRSTEISRKSLPSVAASGTISRNLSALRIARLGLILTGPNS
PMPQAIAAVESASTALNASVEAAAPLFTSAEERPLYEELRNQVAAYSSTLPQQLQHARNNDIDAVRAIFVGPAAVAYRAA
NKALDDLIAINNKGSDLAAERAAATYREGRVQLAAGLVAMIALSAVIAVLLAGNLSRRSRQGMDAALRMARGELGHPLAT
SGKDELAQMMQALEATREHLRTTVGNVRQNAEAVATASAEISQGNQDLSGRTESQASALEQTAASMEELGTTVQQNADSA
RQANQLAKNAAMVAVQGGEVVGQVVETMKGINESSRQIADIIQVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEV
RSLAGRSADAAKEIKNLIGASVERVAAGNALVDQAGATMQEIVGAINRVTDIMGEISAASVEQASGVSQVGEAVTQMDRA
TQQNAALVEEMAAAAGSLKKQAEDLVRGVATFQLGDGRLAMSSAASASSGPMELRRPVALSSQSGPALALAAAGTAS

Sequences:

>Translated_557_residues
MMTLDNWMMRTKLLAGFGLVLVIACIVSLLGVANLSSMNDRSTEISRKSLPSVAASGTISRNLSALRIARLGLILTGPNS
PMPQAIAAVESASTALNASVEAAAPLFTSAEERPLYEELRNQVAAYSSTLPQQLQHARNNDIDAVRAIFVGPAAVAYRAA
NKALDDLIAINNKGSDLAAERAAATYREGRVQLAAGLVAMIALSAVIAVLLAGNLSRRSRQGMDAALRMARGELGHPLAT
SGKDELAQMMQALEATREHLRTTVGNVRQNAEAVATASAEISQGNQDLSGRTESQASALEQTAASMEELGTTVQQNADSA
RQANQLAKNAAMVAVQGGEVVGQVVETMKGINESSRQIADIIQVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEV
RSLAGRSADAAKEIKNLIGASVERVAAGNALVDQAGATMQEIVGAINRVTDIMGEISAASVEQASGVSQVGEAVTQMDRA
TQQNAALVEEMAAAAGSLKKQAEDLVRGVATFQLGDGRLAMSSAASASSGPMELRRPVALSSQSGPALALAAAGTAS
>Mature_557_residues
MMTLDNWMMRTKLLAGFGLVLVIACIVSLLGVANLSSMNDRSTEISRKSLPSVAASGTISRNLSALRIARLGLILTGPNS
PMPQAIAAVESASTALNASVEAAAPLFTSAEERPLYEELRNQVAAYSSTLPQQLQHARNNDIDAVRAIFVGPAAVAYRAA
NKALDDLIAINNKGSDLAAERAAATYREGRVQLAAGLVAMIALSAVIAVLLAGNLSRRSRQGMDAALRMARGELGHPLAT
SGKDELAQMMQALEATREHLRTTVGNVRQNAEAVATASAEISQGNQDLSGRTESQASALEQTAASMEELGTTVQQNADSA
RQANQLAKNAAMVAVQGGEVVGQVVETMKGINESSRQIADIIQVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEV
RSLAGRSADAAKEIKNLIGASVERVAAGNALVDQAGATMQEIVGAINRVTDIMGEISAASVEQASGVSQVGEAVTQMDRA
TQQNAALVEEMAAAAGSLKKQAEDLVRGVATFQLGDGRLAMSSAASASSGPMELRRPVALSSQSGPALALAAAGTAS

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1788194, Length=304, Percent_Identity=55.5921052631579, Blast_Score=298, Evalue=5e-82,
Organism=Escherichia coli, GI1788195, Length=323, Percent_Identity=55.1083591331269, Blast_Score=297, Evalue=1e-81,
Organism=Escherichia coli, GI2367378, Length=344, Percent_Identity=52.6162790697674, Blast_Score=294, Evalue=1e-80,
Organism=Escherichia coli, GI1787690, Length=461, Percent_Identity=42.5162689804772, Blast_Score=289, Evalue=3e-79,
Organism=Escherichia coli, GI1789453, Length=288, Percent_Identity=40.9722222222222, Blast_Score=201, Evalue=1e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 57461; Mature: 57461

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS00287 CYSTATIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTLDNWMMRTKLLAGFGLVLVIACIVSLLGVANLSSMNDRSTEISRKSLPSVAASGTIS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHCCCHH
RNLSALRIARLGLILTGPNSPMPQAIAAVESASTALNASVEAAAPLFTSAEERPLYEELR
HHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHH
NQVAAYSSTLPQQLQHARNNDIDAVRAIFVGPAAVAYRAANKALDDLIAINNKGSDLAAE
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
RAAATYREGRVQLAAGLVAMIALSAVIAVLLAGNLSRRSRQGMDAALRMARGELGHPLAT
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCC
SGKDELAQMMQALEATREHLRTTVGNVRQNAEAVATASAEISQGNQDLSGRTESQASALE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
QTAASMEELGTTVQQNADSARQANQLAKNAAMVAVQGGEVVGQVVETMKGINESSRQIAD
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHCCCHHHHHHHH
IIQVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRSLAGRSADAAKEIKNLIGA
HHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
SVERVAAGNALVDQAGATMQEIVGAINRVTDIMGEISAASVEQASGVSQVGEAVTQMDRA
HHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
TQQNAALVEEMAAAAGSLKKQAEDLVRGVATFQLGDGRLAMSSAASASSGPMELRRPVAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEHHHCCCCCCCCHHHHCCCCC
SSQSGPALALAAAGTAS
CCCCCCEEEEECCCCCC
>Mature Secondary Structure
MMTLDNWMMRTKLLAGFGLVLVIACIVSLLGVANLSSMNDRSTEISRKSLPSVAASGTIS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHCCCHH
RNLSALRIARLGLILTGPNSPMPQAIAAVESASTALNASVEAAAPLFTSAEERPLYEELR
HHHHHHHHHHHCEEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHH
NQVAAYSSTLPQQLQHARNNDIDAVRAIFVGPAAVAYRAANKALDDLIAINNKGSDLAAE
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
RAAATYREGRVQLAAGLVAMIALSAVIAVLLAGNLSRRSRQGMDAALRMARGELGHPLAT
HHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCC
SGKDELAQMMQALEATREHLRTTVGNVRQNAEAVATASAEISQGNQDLSGRTESQASALE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
QTAASMEELGTTVQQNADSARQANQLAKNAAMVAVQGGEVVGQVVETMKGINESSRQIAD
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHCCCHHHHHHHH
IIQVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRSLAGRSADAAKEIKNLIGA
HHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHH
SVERVAAGNALVDQAGATMQEIVGAINRVTDIMGEISAASVEQASGVSQVGEAVTQMDRA
HHHHHHCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
TQQNAALVEEMAAAAGSLKKQAEDLVRGVATFQLGDGRLAMSSAASASSGPMELRRPVAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEHHHCCCCCCCCHHHHCCCCC
SSQSGPALALAAAGTAS
CCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]