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The map label for this gene is ycgM [C]

Identifier: 120612516

GI number: 120612516

Start: 4299108

End: 4299959

Strand: Reverse

Name: ycgM [C]

Synonym: Aave_3875

Alternate gene names: 120612516

Gene position: 4299959-4299108 (Counterclockwise)

Preceding gene: 120612517

Following gene: 120612514

Centisome position: 80.33

GC content: 67.14

Gene sequence:

>852_bases
ATGAAATTGGTACGTTACGGCCAGCCTGGCCGGGAAAAGCCCGGACTCGTCGATGCCGAGGGCCGGATACGCGACCTCTC
GGGCCATGTGTCCGACGTGGATCCCGACCTGCTGTCGTCGCCCGAAGCCTGGGCGTCGTTGTCCAGCCTCGATCCTGCGA
GCCTGCCCGTGGTGGATGGGAGCGTGCGCTACGGTCCCCCCGTTGCCCGTGTAGGCAAGATCGTCTGCGTGGGACTCAAC
TACGCGGACCACGCGGCGGAAACGGGGGCGCCGATCCCGGCCGAGCCCATTCTTTTCCTGAAGCCGAGCTCCTGCATCGT
CGGGCCGGACGATACCGTGGTGATTCCCCGCGGCTCCACCAAGACCGACTGGGAGGTCGAACTGGGCGTGGTGATCGGCC
GCAAGGCCTCGTATGTCGCCGAGGGCGATGCGATGGACCATGTGGCGGGCTACACAGTGGTCAATGACGTATCCGAGCGG
GCTTACCAGATGGAGCGCGGAGGCCAGTGGGACAAGGGCAAGGGATGCGACACCTTCGCGCCCATCGGCCCCTGGCTGGT
TTCGAAGGACGAGGTGCCCGACCCGCAAAACCTCCGCCTGTGGCTCGATGTCAACGGCCGGCGCTACCAGGACGGCAGCA
CGCGCACGATGATCTTCCCGGTGGCCAGGCTGGTGAGCTACATCAGCGAATTCATGTCGCTCATGCCGGGCGACATCATC
AGCACCGGAACGCCGCCCGGCGTGGGCCTGGGCCAGAAGCCGCCGGTGTACCTGAAGGCGGGCGACACCATGCGGCTGGG
CATCGAAGGCCTGGGCGAGCAGCGGCAGGCCACGCGCGCCTGGGCGCGCTGA

Upstream 100 bases:

>100_bases
GCCTCCTTCACGACCGGCGCCATCCACATGATCGACGGTGGATGGTCCAACTGACGCAGGTTCGCCGAGAATGTCCGGCA
AACCCCGTCTGGAGATACGC

Downstream 100 bases:

>100_bases
TCCGTTCCGTGCTCCGGTTCCGGTGCGGGCCCTGCCTCAGGCGAGCAGGGCCTGCGCGAACTCGCGGGCGCTGAAGGTTT
CCAGGTCTTCCAGCTTCTCG

Product: 5-carboxymethyl-2-hydroxymuconate delta-isomerase

Products: NA

Alternate protein names: UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MKLVRYGQPGREKPGLVDAEGRIRDLSGHVSDVDPDLLSSPEAWASLSSLDPASLPVVDGSVRYGPPVARVGKIVCVGLN
YADHAAETGAPIPAEPILFLKPSSCIVGPDDTVVIPRGSTKTDWEVELGVVIGRKASYVAEGDAMDHVAGYTVVNDVSER
AYQMERGGQWDKGKGCDTFAPIGPWLVSKDEVPDPQNLRLWLDVNGRRYQDGSTRTMIFPVARLVSYISEFMSLMPGDII
STGTPPGVGLGQKPPVYLKAGDTMRLGIEGLGEQRQATRAWAR

Sequences:

>Translated_283_residues
MKLVRYGQPGREKPGLVDAEGRIRDLSGHVSDVDPDLLSSPEAWASLSSLDPASLPVVDGSVRYGPPVARVGKIVCVGLN
YADHAAETGAPIPAEPILFLKPSSCIVGPDDTVVIPRGSTKTDWEVELGVVIGRKASYVAEGDAMDHVAGYTVVNDVSER
AYQMERGGQWDKGKGCDTFAPIGPWLVSKDEVPDPQNLRLWLDVNGRRYQDGSTRTMIFPVARLVSYISEFMSLMPGDII
STGTPPGVGLGQKPPVYLKAGDTMRLGIEGLGEQRQATRAWAR
>Mature_283_residues
MKLVRYGQPGREKPGLVDAEGRIRDLSGHVSDVDPDLLSSPEAWASLSSLDPASLPVVDGSVRYGPPVARVGKIVCVGLN
YADHAAETGAPIPAEPILFLKPSSCIVGPDDTVVIPRGSTKTDWEVELGVVIGRKASYVAEGDAMDHVAGYTVVNDVSER
AYQMERGGQWDKGKGCDTFAPIGPWLVSKDEVPDPQNLRLWLDVNGRRYQDGSTRTMIFPVARLVSYISEFMSLMPGDII
STGTPPGVGLGQKPPVYLKAGDTMRLGIEGLGEQRQATRAWAR

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI156231349, Length=222, Percent_Identity=53.1531531531532, Blast_Score=238, Evalue=5e-63,
Organism=Homo sapiens, GI40786394, Length=222, Percent_Identity=51.3513513513513, Blast_Score=227, Evalue=1e-59,
Organism=Homo sapiens, GI215422413, Length=209, Percent_Identity=41.1483253588517, Blast_Score=154, Evalue=1e-37,
Organism=Homo sapiens, GI66348062, Length=202, Percent_Identity=41.5841584158416, Blast_Score=152, Evalue=3e-37,
Organism=Homo sapiens, GI13654274, Length=202, Percent_Identity=41.5841584158416, Blast_Score=152, Evalue=4e-37,
Organism=Escherichia coli, GI1787428, Length=203, Percent_Identity=37.4384236453202, Blast_Score=138, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI17557057, Length=199, Percent_Identity=39.6984924623116, Blast_Score=147, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6324161, Length=213, Percent_Identity=33.8028169014084, Blast_Score=115, Evalue=7e-27,
Organism=Drosophila melanogaster, GI28572127, Length=217, Percent_Identity=47.0046082949309, Blast_Score=201, Evalue=5e-52,
Organism=Drosophila melanogaster, GI24663695, Length=275, Percent_Identity=32, Blast_Score=149, Evalue=1e-36,
Organism=Drosophila melanogaster, GI28571789, Length=204, Percent_Identity=40.1960784313725, Blast_Score=148, Evalue=4e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.3.2.3 [H]

Molecular weight: Translated: 30470; Mature: 30470

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVRYGQPGREKPGLVDAEGRIRDLSGHVSDVDPDLLSSPEAWASLSSLDPASLPVVDG
CCCCCCCCCCCCCCCEECCCCCEEECCCCCCCCCHHHHCCCHHHHHHHCCCCCCCCEECC
SVRYGPPVARVGKIVCVGLNYADHAAETGAPIPAEPILFLKPSSCIVGPDDTVVIPRGST
CCCCCCCHHHCCEEEEEECCCHHHHHHCCCCCCCCCEEEECCCCEEECCCCEEEEECCCC
KTDWEVELGVVIGRKASYVAEGDAMDHVAGYTVVNDVSERAYQMERGGQWDKGKGCDTFA
CCCEEEEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
PIGPWLVSKDEVPDPQNLRLWLDVNGRRYQDGSTRTMIFPVARLVSYISEFMSLMPGDII
CCCCEEECCCCCCCCCCEEEEEEECCEEECCCCCEEHHHHHHHHHHHHHHHHHHCCCCEE
STGTPPGVGLGQKPPVYLKAGDTMRLGIEGLGEQRQATRAWAR
CCCCCCCCCCCCCCCEEEECCCEEEECHHCCCHHHHHHHHHCC
>Mature Secondary Structure
MKLVRYGQPGREKPGLVDAEGRIRDLSGHVSDVDPDLLSSPEAWASLSSLDPASLPVVDG
CCCCCCCCCCCCCCCEECCCCCEEECCCCCCCCCHHHHCCCHHHHHHHCCCCCCCCEECC
SVRYGPPVARVGKIVCVGLNYADHAAETGAPIPAEPILFLKPSSCIVGPDDTVVIPRGST
CCCCCCCHHHCCEEEEEECCCHHHHHHCCCCCCCCCEEEECCCCEEECCCCEEEEECCCC
KTDWEVELGVVIGRKASYVAEGDAMDHVAGYTVVNDVSERAYQMERGGQWDKGKGCDTFA
CCCEEEEEEEEECCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
PIGPWLVSKDEVPDPQNLRLWLDVNGRRYQDGSTRTMIFPVARLVSYISEFMSLMPGDII
CCCCEEECCCCCCCCCCEEEEEEECCEEECCCCCEEHHHHHHHHHHHHHHHHHHCCCCEE
STGTPPGVGLGQKPPVYLKAGDTMRLGIEGLGEQRQATRAWAR
CCCCCCCCCCCCCCCEEEECCCEEEECHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA