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The map label for this gene is grx [H]

Identifier: 120612497

GI number: 120612497

Start: 4283473

End: 4283730

Strand: Reverse

Name: grx [H]

Synonym: Aave_3856

Alternate gene names: 120612497

Gene position: 4283730-4283473 (Counterclockwise)

Preceding gene: 120612498

Following gene: 120612496

Centisome position: 80.03

GC content: 67.05

Gene sequence:

>258_bases
ATGCAACCCGTCAAGATGTACACCACCGCCGTCTGCCCCTACTGCATCCGGGCCAAGCAGATCCTCAAGGCCAAGGGCGT
GGAGCAGATCGAGGAGATCCGCGTCGATCTCGATCCCGAGGCCCGTTCCCACATGATGGAGGTCACCGGGCGGCGTACGG
TGCCGCAGATCTTCATCGGCGACACCCACGTGGGCGGCCACGACGACCTGGTCGCGCTGGACGGCCGCGGTGGCCTGATG
CCCCTGCTCGGCGCCTGA

Upstream 100 bases:

>100_bases
CTGAAGGCCTGGCGCGAGGCCGGCATGCCGGTTGAAAAGGCCTGAAGCGGCACCACGTGCTCTTTCGTACCCTCACGCAA
TCTTCCAGGAAGGCCGCCCC

Downstream 100 bases:

>100_bases
AAGGCGCGCTGGCCGGGCGCTGCATAATGCGGCCCCGGGTGCTGCCCGCTGCGGGAACGCGATGTCCCCGGCGGGCTTTG
TCTTACCTGCCCCTTTCCCC

Product: glutaredoxin 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 85; Mature: 85

Protein sequence:

>85_residues
MQPVKMYTTAVCPYCIRAKQILKAKGVEQIEEIRVDLDPEARSHMMEVTGRRTVPQIFIGDTHVGGHDDLVALDGRGGLM
PLLGA

Sequences:

>Translated_85_residues
MQPVKMYTTAVCPYCIRAKQILKAKGVEQIEEIRVDLDPEARSHMMEVTGRRTVPQIFIGDTHVGGHDDLVALDGRGGLM
PLLGA
>Mature_85_residues
MQPVKMYTTAVCPYCIRAKQILKAKGVEQIEEIRVDLDPEARSHMMEVTGRRTVPQIFIGDTHVGGHDDLVALDGRGGLM
PLLGA

Specific function: Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins [H]

COG id: COG0695

COG function: function code O; Glutaredoxin and related proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutaredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790039, Length=83, Percent_Identity=53.0120481927711, Blast_Score=90, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011767
- InterPro:   IPR002109
- InterPro:   IPR014025
- InterPro:   IPR011900
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00462 Glutaredoxin [H]

EC number: NA

Molecular weight: Translated: 9346; Mature: 9346

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00195 GLUTAREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
8.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
5.9 %Met     (Mature Protein)
8.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPVKMYTTAVCPYCIRAKQILKAKGVEQIEEIRVDLDPEARSHMMEVTGRRTVPQIFIG
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEC
DTHVGGHDDLVALDGRGGLMPLLGA
CCCCCCCCCEEEECCCCCCCCCCCC
>Mature Secondary Structure
MQPVKMYTTAVCPYCIRAKQILKAKGVEQIEEIRVDLDPEARSHMMEVTGRRTVPQIFIG
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEC
DTHVGGHDDLVALDGRGGLMPLLGA
CCCCCCCCCEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]