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The map label for this gene is ydeP [H]

Identifier: 120612468

GI number: 120612468

Start: 4251266

End: 4253599

Strand: Reverse

Name: ydeP [H]

Synonym: Aave_3827

Alternate gene names: 120612468

Gene position: 4253599-4251266 (Counterclockwise)

Preceding gene: 120612469

Following gene: 120612467

Centisome position: 79.47

GC content: 69.62

Gene sequence:

>2334_bases
ATGAGCGAACAGAAAATCGAGTTCTACAAAGGCCCTGCGGGCGGCTGGGGCGCGCTCAACAGCGTGAAGAACACCCTGCT
GCGGCAGGACATCCCCCTCAAGGGCGCGAAAACGCTCCTCTCGGCGAACCAGCCCGACGGCTTCGACTGCCCCGGCTGCG
CCTGGCCGGACCGCAACCATGCCTCCACCTTCGAGTTCTGCGAAAACGGCGCCAAGGCCGTGGCGGCGGAGGCCACCGCC
CGTCGCGCCGGGCCGGAACTGTTCGCGCGCCACACGGTCGCCGAGCTGGCCGCCCAGAGCGACTTCTGGCTGGAAGACCA
GGGCCGCCTCACGCACCCCATGGTGTACGACGCCGCGAGCGACCGCTACGTGCCGATCGCCTGGGACGACGCCTTCGCGC
TCGTCGCCAGGCACCTGAACGCGCTGCCCGACCCCGACCAGGCGATCTTCTACACCTCGGGCCGTGCGAGCAACGAAGCC
GCGTTCCTCTACCAATTGTTCGTGCGCGAATACGGCACGAACAATTTCCCGGACTGCTCCAACATGTGCCACGAGCCCAG
CGGCAGCGCCATGCGCCCGCAGATCGGCGTGGGCAAGGGCACGGTCACGCTGCAGGATTTCGAGCAGGCCGACGCGATCT
TCATCTTCGGCCAGAACCCCGGCACCAACCACCCGCGGATGCTGGGCGAGCTGCGCGAGGCCCACAAGCGCGGTGCGCAG
ATCGTGAGCTTCAATCCGCTGCGCGAGCGCGGCCTGGAGCGCTTCGCCGACCCGCAGAACAAGATGGAGATGGCCACCCT
GGGCTCCACGCCGATCAGCACGCACTACTTCCAGGTGCGCGTGGGCGGCGACCTGGCCGTGGTCAAGGGCATGATGAAGC
ATCTGGTGGAGGCCGAGTACCGCGAGGGCGGCGTGCTGGACCATGCCTTCATCCGGGAGCACACCACGGGCGTCGAGGCG
CTGCTGGCGGACCTGCGCGCCGAGTCCTGGGCGCTGATCGAGCAGGAGTCGGGCCTGTCCGAGGCGCAGATCCGGGCCGC
CGCCGAGGTCTATCGCCAGGCCCGCAGCGTCATCGCCTGCTGGGGCATGGGCATCACACAGCACATGCATTCCGTGGCGA
CGATCCAGATGATCGTCAACTGGCTGCTGCTGCGCGGCAACATCGGCCGCCCGGGCGCGGGCCCGTGCCCCGTGCGGGGC
CACAGCAACGTGCAGGGCGACCGCACCATGGGCATCTGGGAAAAGCCCCCGGCCGCGCTGCTGGACCGCCTGCAGGAGGT
CTTCGGCTTCGAGCCGCCGCGCGAGCCCGGCGTGGACACGGTGGAGGCCATCCAGGCCATGCTGGACGGCAAGGCGCGCG
TCTTCTTCGCGCTGGGCGGCAATTTCGCCGCCGCCACCCCGGACACCTACGAAACCTGGAAGGCGCTGCAGCGCTGCGAC
CTCACGGTGCACGTGACGACCAAGCTCAACCGCAGCCACATCGTGCACGGGCGCGAGGCCCTGATCCTGCCCTGCCTGGG
CCGCACCGAGATCGACATGCAGGCCGCCGGCCCGCAGGGCGTGACGGTGGAGGACTCCATGAGCATGGTGCACATCTCCG
TGGGCATCAACCCGCCCGCATCCGGGCACCTGCTGTCCGAGCCCGCCATCGTCGCGCGGCTGGCCGCGGCCACGCTGGGC
GCGCGCAGCCGCGTTCCCTGGCTCTGGATGATCGAGGACTACGCCCGCATCCGCGACAAGATCGAGCAGGTGTTCCCCGA
CTTCAAGGATTTCAACCGGCGCATCGCGGTGCCGGGCGGTTTCCGGCTGCGCAACACGGCCAGCGAGCGCATCTGGAACA
CCGGGCCGCACAAGGCCGTCTTCGTGGCCCACCCGGTGCCGCAGGACACGCCGGTGCACCAGGCCCGCGCCCGCACGCGC
GACACCGTGGTGTTCACGCTGCTCACCACGCGCTCGCACGACCAGTACAACACCACCATCTACGGCCACGACGACCGCTA
CCGGGGTGTCTATGGGCAGCGCCGCGTGGTCTTCATCCACCCCGAGGACATCCGCGCGCTGGGCATGAAGGACGGCGACT
GGGTCGATATCCAGACCGTGTGGAGCGACGGACAGGAGCGGCGTGCCGACCGCTTCAAGCTCGTCGGCTACGACATCCCG
CGCGGCAATCTCGCGGCCTACTACCCCGAGACGAACCCGCTGGTGCCGCTGTCGTCCGTGGCGCTGAACGCGGGCACGCC
GACTTCCAAGTCCATCCCCGTCGTGCTGGTGCCCAGCGCCGCCGGGGCCGCGGCAGCAGGCCCGTCCGCCGAAGTGGCGC
CCGCCGCCGTCTGA

Upstream 100 bases:

>100_bases
GGCCGGGGTATCGGGCGTAGCCTTCCGGGCGATGTGTCCGGCGCGGTGCCGGCGGGCACGCTCCCTCCATCCGCGATGAT
TCCGTTCCAAGGAGACCACG

Downstream 100 bases:

>100_bases
GCCCGCCTTGACCGTTCCGGACGACGATTTCACCGCTGCACTGCTCGCGGCGCTCGCCGAACTCGACGCGCCGCAGGGCG
TGTCCCTGCCGCGCCTCGCC

Product: oxidoreductase alpha (molybdopterin) subunit

Products: CO2; NADH

Alternate protein names: NA

Number of amino acids: Translated: 777; Mature: 776

Protein sequence:

>777_residues
MSEQKIEFYKGPAGGWGALNSVKNTLLRQDIPLKGAKTLLSANQPDGFDCPGCAWPDRNHASTFEFCENGAKAVAAEATA
RRAGPELFARHTVAELAAQSDFWLEDQGRLTHPMVYDAASDRYVPIAWDDAFALVARHLNALPDPDQAIFYTSGRASNEA
AFLYQLFVREYGTNNFPDCSNMCHEPSGSAMRPQIGVGKGTVTLQDFEQADAIFIFGQNPGTNHPRMLGELREAHKRGAQ
IVSFNPLRERGLERFADPQNKMEMATLGSTPISTHYFQVRVGGDLAVVKGMMKHLVEAEYREGGVLDHAFIREHTTGVEA
LLADLRAESWALIEQESGLSEAQIRAAAEVYRQARSVIACWGMGITQHMHSVATIQMIVNWLLLRGNIGRPGAGPCPVRG
HSNVQGDRTMGIWEKPPAALLDRLQEVFGFEPPREPGVDTVEAIQAMLDGKARVFFALGGNFAAATPDTYETWKALQRCD
LTVHVTTKLNRSHIVHGREALILPCLGRTEIDMQAAGPQGVTVEDSMSMVHISVGINPPASGHLLSEPAIVARLAAATLG
ARSRVPWLWMIEDYARIRDKIEQVFPDFKDFNRRIAVPGGFRLRNTASERIWNTGPHKAVFVAHPVPQDTPVHQARARTR
DTVVFTLLTTRSHDQYNTTIYGHDDRYRGVYGQRRVVFIHPEDIRALGMKDGDWVDIQTVWSDGQERRADRFKLVGYDIP
RGNLAAYYPETNPLVPLSSVALNAGTPTSKSIPVVLVPSAAGAAAAGPSAEVAPAAV

Sequences:

>Translated_777_residues
MSEQKIEFYKGPAGGWGALNSVKNTLLRQDIPLKGAKTLLSANQPDGFDCPGCAWPDRNHASTFEFCENGAKAVAAEATA
RRAGPELFARHTVAELAAQSDFWLEDQGRLTHPMVYDAASDRYVPIAWDDAFALVARHLNALPDPDQAIFYTSGRASNEA
AFLYQLFVREYGTNNFPDCSNMCHEPSGSAMRPQIGVGKGTVTLQDFEQADAIFIFGQNPGTNHPRMLGELREAHKRGAQ
IVSFNPLRERGLERFADPQNKMEMATLGSTPISTHYFQVRVGGDLAVVKGMMKHLVEAEYREGGVLDHAFIREHTTGVEA
LLADLRAESWALIEQESGLSEAQIRAAAEVYRQARSVIACWGMGITQHMHSVATIQMIVNWLLLRGNIGRPGAGPCPVRG
HSNVQGDRTMGIWEKPPAALLDRLQEVFGFEPPREPGVDTVEAIQAMLDGKARVFFALGGNFAAATPDTYETWKALQRCD
LTVHVTTKLNRSHIVHGREALILPCLGRTEIDMQAAGPQGVTVEDSMSMVHISVGINPPASGHLLSEPAIVARLAAATLG
ARSRVPWLWMIEDYARIRDKIEQVFPDFKDFNRRIAVPGGFRLRNTASERIWNTGPHKAVFVAHPVPQDTPVHQARARTR
DTVVFTLLTTRSHDQYNTTIYGHDDRYRGVYGQRRVVFIHPEDIRALGMKDGDWVDIQTVWSDGQERRADRFKLVGYDIP
RGNLAAYYPETNPLVPLSSVALNAGTPTSKSIPVVLVPSAAGAAAAGPSAEVAPAAV
>Mature_776_residues
SEQKIEFYKGPAGGWGALNSVKNTLLRQDIPLKGAKTLLSANQPDGFDCPGCAWPDRNHASTFEFCENGAKAVAAEATAR
RAGPELFARHTVAELAAQSDFWLEDQGRLTHPMVYDAASDRYVPIAWDDAFALVARHLNALPDPDQAIFYTSGRASNEAA
FLYQLFVREYGTNNFPDCSNMCHEPSGSAMRPQIGVGKGTVTLQDFEQADAIFIFGQNPGTNHPRMLGELREAHKRGAQI
VSFNPLRERGLERFADPQNKMEMATLGSTPISTHYFQVRVGGDLAVVKGMMKHLVEAEYREGGVLDHAFIREHTTGVEAL
LADLRAESWALIEQESGLSEAQIRAAAEVYRQARSVIACWGMGITQHMHSVATIQMIVNWLLLRGNIGRPGAGPCPVRGH
SNVQGDRTMGIWEKPPAALLDRLQEVFGFEPPREPGVDTVEAIQAMLDGKARVFFALGGNFAAATPDTYETWKALQRCDL
TVHVTTKLNRSHIVHGREALILPCLGRTEIDMQAAGPQGVTVEDSMSMVHISVGINPPASGHLLSEPAIVARLAAATLGA
RSRVPWLWMIEDYARIRDKIEQVFPDFKDFNRRIAVPGGFRLRNTASERIWNTGPHKAVFVAHPVPQDTPVHQARARTRD
TVVFTLLTTRSHDQYNTTIYGHDDRYRGVYGQRRVVFIHPEDIRALGMKDGDWVDIQTVWSDGQERRADRFKLVGYDIPR
GNLAAYYPETNPLVPLSSVALNAGTPTSKSIPVVLVPSAAGAAAAGPSAEVAPAAV

Specific function: Probably involved in acid resistance [H]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787778, Length=764, Percent_Identity=50.261780104712, Blast_Score=763, Evalue=0.0,
Organism=Escherichia coli, GI3868721, Length=390, Percent_Identity=27.6923076923077, Blast_Score=154, Evalue=2e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR010046 [H]

Pfam domain/function: PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.2.1.2

Molecular weight: Translated: 85327; Mature: 85195

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEQKIEFYKGPAGGWGALNSVKNTLLRQDIPLKGAKTLLSANQPDGFDCPGCAWPDRNH
CCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCC
ASTFEFCENGAKAVAAEATARRAGPELFARHTVAELAAQSDFWLEDQGRLTHPMVYDAAS
CHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEECCCCCCCCCEEEECCC
DRYVPIAWDDAFALVARHLNALPDPDQAIFYTSGRASNEAAFLYQLFVREYGTNNFPDCS
CCEEEEEECHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCHH
NMCHEPSGSAMRPQIGVGKGTVTLQDFEQADAIFIFGQNPGTNHPRMLGELREAHKRGAQ
HHCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCE
IVSFNPLRERGLERFADPQNKMEMATLGSTPISTHYFQVRVGGDLAVVKGMMKHLVEAEY
EEEECHHHHHHHHHHCCCCHHEEEEECCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHH
REGGVLDHAFIREHTTGVEALLADLRAESWALIEQESGLSEAQIRAAAEVYRQARSVIAC
HCCCCCHHHHHHHHCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
WGMGITQHMHSVATIQMIVNWLLLRGNIGRPGAGPCPVRGHSNVQGDRTMGIWEKPPAAL
HCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCHHHH
LDRLQEVFGFEPPREPGVDTVEAIQAMLDGKARVFFALGGNFAAATPDTYETWKALQRCD
HHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCEEECCCCHHHHHHHHHHCC
LTVHVTTKLNRSHIVHGREALILPCLGRTEIDMQAAGPQGVTVEDSMSMVHISVGINPPA
EEEEEEEECCCHHEECCCCEEEEECCCCCCEEEECCCCCCCEEECCCEEEEEEECCCCCC
SGHLLSEPAIVARLAAATLGARSRVPWLWMIEDYARIRDKIEQVFPDFKDFNRRIAVPGG
CCCCCCCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHCCCHHHCCCEEECCCC
FRLRNTASERIWNTGPHKAVFVAHPVPQDTPVHQARARTRDTVVFTLLTTRSHDQYNTTI
CEECCCHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHCCCCEEEEEEEEECCCCCCCCEE
YGHDDRYRGVYGQRRVVFIHPEDIRALGMKDGDWVDIQTVWSDGQERRADRFKLVGYDIP
ECCCCCCCCCCCCCEEEEECCCCHHEECCCCCCEEEEEEECCCCHHHCCCCEEEEEEECC
RGNLAAYYPETNPLVPLSSVALNAGTPTSKSIPVVLVPSAAGAAAAGPSAEVAPAAV
CCCEEEECCCCCCCCCHHHEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SEQKIEFYKGPAGGWGALNSVKNTLLRQDIPLKGAKTLLSANQPDGFDCPGCAWPDRNH
CCCCEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCC
ASTFEFCENGAKAVAAEATARRAGPELFARHTVAELAAQSDFWLEDQGRLTHPMVYDAAS
CHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEECCCCCCCCCEEEECCC
DRYVPIAWDDAFALVARHLNALPDPDQAIFYTSGRASNEAAFLYQLFVREYGTNNFPDCS
CCEEEEEECHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCHH
NMCHEPSGSAMRPQIGVGKGTVTLQDFEQADAIFIFGQNPGTNHPRMLGELREAHKRGAQ
HHCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCE
IVSFNPLRERGLERFADPQNKMEMATLGSTPISTHYFQVRVGGDLAVVKGMMKHLVEAEY
EEEECHHHHHHHHHHCCCCHHEEEEECCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHH
REGGVLDHAFIREHTTGVEALLADLRAESWALIEQESGLSEAQIRAAAEVYRQARSVIAC
HCCCCCHHHHHHHHCHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
WGMGITQHMHSVATIQMIVNWLLLRGNIGRPGAGPCPVRGHSNVQGDRTMGIWEKPPAAL
HCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCHHHH
LDRLQEVFGFEPPREPGVDTVEAIQAMLDGKARVFFALGGNFAAATPDTYETWKALQRCD
HHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEEEEEECCCEEECCCCHHHHHHHHHHCC
LTVHVTTKLNRSHIVHGREALILPCLGRTEIDMQAAGPQGVTVEDSMSMVHISVGINPPA
EEEEEEEECCCHHEECCCCEEEEECCCCCCEEEECCCCCCCEEECCCEEEEEEECCCCCC
SGHLLSEPAIVARLAAATLGARSRVPWLWMIEDYARIRDKIEQVFPDFKDFNRRIAVPGG
CCCCCCCHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHCCCHHHCCCEEECCCC
FRLRNTASERIWNTGPHKAVFVAHPVPQDTPVHQARARTRDTVVFTLLTTRSHDQYNTTI
CEECCCHHHHHCCCCCCCEEEEECCCCCCCCCHHHHHCCCCEEEEEEEEECCCCCCCCEE
YGHDDRYRGVYGQRRVVFIHPEDIRALGMKDGDWVDIQTVWSDGQERRADRFKLVGYDIP
ECCCCCCCCCCCCCEEEEECCCCHHEECCCCCCEEEEEEECCCCHHHCCCCEEEEEEECC
RGNLAAYYPETNPLVPLSSVALNAGTPTSKSIPVVLVPSAAGAAAAGPSAEVAPAAV
CCCEEEECCCCCCCCCHHHEEEECCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formate; NAD+

Specific reaction: formate + NAD+ = CO2 + NADH

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]