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The map label for this gene is ytfL [H]

Identifier: 120612312

GI number: 120612312

Start: 4044655

End: 4046013

Strand: Direct

Name: ytfL [H]

Synonym: Aave_3668

Alternate gene names: 120612312

Gene position: 4044655-4046013 (Clockwise)

Preceding gene: 120612311

Following gene: 120612315

Centisome position: 75.56

GC content: 67.99

Gene sequence:

>1359_bases
ATGGCGGCGCCCGCCCGTCCCATGACCCTGTCGCAAAGCTTCTTCCTCATCGGCCTCCTCATCGTGGCCAGCGCCTTCTT
CTCCGTCGCGGAGATCTCCCTGGCTGCCTCCCGCCGCCTGCGCCTGCGCCAGCTCGCCGACGAGGGCGAAGCGCGCGCCG
AGAGCGTCATGCGCATGCAGGAGCAGCCAGGCGACTATTTCACCGTGGTGCAGGTGGGCCAGAACGCCGTGGCCATCCTC
GGCGGCATCGTCGGCGAAGGCGCGCTCAGCCCCCAATTCACCGCCCTGCTCCAGTTCTGGCTCAGCGACGCGCGTGCCGA
AACCTTCGGCTTCCTGGCATCGTTTCTGACCATCACCTCGCTCTTCATCCTGTTCGCCGACCTGTTCCCCAAGCGCCTGG
GCATGGTCAACTCCGAGCGCCTCGCCGTGGTCGTCGCGCGGCCCATGGCGATTCTCATGGCGGTGCTGCGGCCCGTCGTC
TGGCTTTACAGCCGCGCCGCCGACCTGCTGTTCCGTGTGCTCGGCCTGTCGTCACTGCGCGACGACCGCATCACGTCCGA
CGACATCCTGGCCATGATGGAGGCCGGTACCCGGGCCGGCGTGCTGGCGGCGCGCGAGCAGCAGGTGATCGAGAACGTGT
TCGAACTCGACTCCCGCCCGGTGAGCAGCGCCATGTCGCCGCGCGACCGGATCGCCTTCTTCCTGCGCGACGATCCGGAC
CAGCTCATCCGCGCCCGCATCGCCGCGGAGCCCTTCTCCACCTACCCCGTGTGCGAGGGAGATATCGACCACGTCGTCGG
CTACGTCGATGCCAAGGACCTTTTCCAGCGCGTGCTGAACAACCAGCCCATCTCCCTGAAGGACGAAGGCCTCGTGCGCA
AGGTACTCATCGTGCCCGACCGCCTTTCGCTGGCCGAGGTGCTGGACCAGTTCCGCCAGGTGCACGAGGATTTCGCCGTC
ATCGTCAACGAGTACAGCCTCGTCGTGGGCGTCGTCACCCTGAACGACGTGATGAGCACGGTGATGGGCGACCTGATCGG
CCCCGACGACGAGGAGCAGATCGTCCGGCGCGACGAGAACTCCTGGCTGATCGACGGCGTCACGCCCGTGGGCGACGTGC
TGCGGGCCCTGCACCTCGACGAACTGCCCCATGCCGGCGAATACGAAACCCTGGCGGGCTTCCTCATGGTCATGCTGCGC
CGCGTGCCCCGCCGCACGGACAGCGTGAACTGGGGCGGCTACAAGTTCGAGGTGCTCGACGTGGACAGCTACCGCATCGA
CCAGATCATGGTGTCGCGCCTGCAGGAAGGCGGCGCCCATCCCGCCGGGCCCGGGCCGGCACCGGCCCCGGGCGGCTGA

Upstream 100 bases:

>100_bases
GATCCGCCGCGCAAGCCGGCTGGACTGTTCCGCACGGCCGCGCCCGCACGGCCCGCGTACACTCGGGACGCTGGCGCACG
GCCCTCCACACGACAACTCC

Downstream 100 bases:

>100_bases
ACGCGGCGCATCGGCCTGCTCAGGCGGACCGGACGCGGTCCTCGAACAGCCAGTTGCGCTGCGCCGCGAACACCGCGTCC
GGGTACGGCGAACGCCCGCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MAAPARPMTLSQSFFLIGLLIVASAFFSVAEISLAASRRLRLRQLADEGEARAESVMRMQEQPGDYFTVVQVGQNAVAIL
GGIVGEGALSPQFTALLQFWLSDARAETFGFLASFLTITSLFILFADLFPKRLGMVNSERLAVVVARPMAILMAVLRPVV
WLYSRAADLLFRVLGLSSLRDDRITSDDILAMMEAGTRAGVLAAREQQVIENVFELDSRPVSSAMSPRDRIAFFLRDDPD
QLIRARIAAEPFSTYPVCEGDIDHVVGYVDAKDLFQRVLNNQPISLKDEGLVRKVLIVPDRLSLAEVLDQFRQVHEDFAV
IVNEYSLVVGVVTLNDVMSTVMGDLIGPDDEEQIVRRDENSWLIDGVTPVGDVLRALHLDELPHAGEYETLAGFLMVMLR
RVPRRTDSVNWGGYKFEVLDVDSYRIDQIMVSRLQEGGAHPAGPGPAPAPGG

Sequences:

>Translated_452_residues
MAAPARPMTLSQSFFLIGLLIVASAFFSVAEISLAASRRLRLRQLADEGEARAESVMRMQEQPGDYFTVVQVGQNAVAIL
GGIVGEGALSPQFTALLQFWLSDARAETFGFLASFLTITSLFILFADLFPKRLGMVNSERLAVVVARPMAILMAVLRPVV
WLYSRAADLLFRVLGLSSLRDDRITSDDILAMMEAGTRAGVLAAREQQVIENVFELDSRPVSSAMSPRDRIAFFLRDDPD
QLIRARIAAEPFSTYPVCEGDIDHVVGYVDAKDLFQRVLNNQPISLKDEGLVRKVLIVPDRLSLAEVLDQFRQVHEDFAV
IVNEYSLVVGVVTLNDVMSTVMGDLIGPDDEEQIVRRDENSWLIDGVTPVGDVLRALHLDELPHAGEYETLAGFLMVMLR
RVPRRTDSVNWGGYKFEVLDVDSYRIDQIMVSRLQEGGAHPAGPGPAPAPGG
>Mature_451_residues
AAPARPMTLSQSFFLIGLLIVASAFFSVAEISLAASRRLRLRQLADEGEARAESVMRMQEQPGDYFTVVQVGQNAVAILG
GIVGEGALSPQFTALLQFWLSDARAETFGFLASFLTITSLFILFADLFPKRLGMVNSERLAVVVARPMAILMAVLRPVVW
LYSRAADLLFRVLGLSSLRDDRITSDDILAMMEAGTRAGVLAAREQQVIENVFELDSRPVSSAMSPRDRIAFFLRDDPDQ
LIRARIAAEPFSTYPVCEGDIDHVVGYVDAKDLFQRVLNNQPISLKDEGLVRKVLIVPDRLSLAEVLDQFRQVHEDFAVI
VNEYSLVVGVVTLNDVMSTVMGDLIGPDDEEQIVRRDENSWLIDGVTPVGDVLRALHLDELPHAGEYETLAGFLMVMLRR
VPRRTDSVNWGGYKFEVLDVDSYRIDQIMVSRLQEGGAHPAGPGPAPAPGG

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=385, Percent_Identity=24.9350649350649, Blast_Score=153, Evalue=3e-37,
Organism=Escherichia coli, GI1790664, Length=423, Percent_Identity=53.9007092198582, Blast_Score=486, Evalue=1e-138,
Organism=Escherichia coli, GI87082033, Length=284, Percent_Identity=30.9859154929577, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI145693175, Length=418, Percent_Identity=23.6842105263158, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1788119, Length=279, Percent_Identity=26.8817204301075, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1786879, Length=272, Percent_Identity=23.1617647058824, Blast_Score=75, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 49847; Mature: 49716

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAPARPMTLSQSFFLIGLLIVASAFFSVAEISLAASRRLRLRQLADEGEARAESVMRMQ
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQPGDYFTVVQVGQNAVAILGGIVGEGALSPQFTALLQFWLSDARAETFGFLASFLTITS
HCCCCEEEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFILFADLFPKRLGMVNSERLAVVVARPMAILMAVLRPVVWLYSRAADLLFRVLGLSSLR
HHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DDRITSDDILAMMEAGTRAGVLAAREQQVIENVFELDSRPVSSAMSPRDRIAFFLRDDPD
CCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHEEEEEECCHH
QLIRARIAAEPFSTYPVCEGDIDHVVGYVDAKDLFQRVLNNQPISLKDEGLVRKVLIVPD
HHHHHHHHCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHEEEEECCC
RLSLAEVLDQFRQVHEDFAVIVNEYSLVVGVVTLNDVMSTVMGDLIGPDDEEQIVRRDEN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCC
SWLIDGVTPVGDVLRALHLDELPHAGEYETLAGFLMVMLRRVPRRTDSVNWGGYKFEVLD
CEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEE
VDSYRIDQIMVSRLQEGGAHPAGPGPAPAPGG
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AAPARPMTLSQSFFLIGLLIVASAFFSVAEISLAASRRLRLRQLADEGEARAESVMRMQ
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQPGDYFTVVQVGQNAVAILGGIVGEGALSPQFTALLQFWLSDARAETFGFLASFLTITS
HCCCCEEEEEEECCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFILFADLFPKRLGMVNSERLAVVVARPMAILMAVLRPVVWLYSRAADLLFRVLGLSSLR
HHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DDRITSDDILAMMEAGTRAGVLAAREQQVIENVFELDSRPVSSAMSPRDRIAFFLRDDPD
CCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCHHHEEEEEECCHH
QLIRARIAAEPFSTYPVCEGDIDHVVGYVDAKDLFQRVLNNQPISLKDEGLVRKVLIVPD
HHHHHHHHCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHCCCCCCCCCCCHHEEEEECCC
RLSLAEVLDQFRQVHEDFAVIVNEYSLVVGVVTLNDVMSTVMGDLIGPDDEEQIVRRDEN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCC
SWLIDGVTPVGDVLRALHLDELPHAGEYETLAGFLMVMLRRVPRRTDSVNWGGYKFEVLD
CEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEE
VDSYRIDQIMVSRLQEGGAHPAGPGPAPAPGG
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]