Click here to switch to the map view.

The map label for this gene is ybhO [H]

Identifier: 120612278

GI number: 120612278

Start: 4004468

End: 4005736

Strand: Reverse

Name: ybhO [H]

Synonym: Aave_3632

Alternate gene names: 120612278

Gene position: 4005736-4004468 (Counterclockwise)

Preceding gene: 120612279

Following gene: 120612277

Centisome position: 74.83

GC content: 74.07

Gene sequence:

>1269_bases
GTGCCCCGCTTCACCCTGCGCCGGCGCCGCGCGGCTCCGGCCCCCTTGTCCGGCGGGCACCGCGTCGCGCTGCTGCAGGG
CTCGGCGGAGCTGTTCGCCGCGCTGATGGCCGACATGGATGCGGCGCTCTCGGACATCCAGTTCGAGACCTACATCTTCG
ACTGCACCGGCTCCGGGGCCGACATCGCGGAGGCGCTGATCCGCGCGGCCCGCCGGGGCGTGCGCGTGCAGCTCGTGGTG
GACGGGGTGGGCACGGGCCGCCTCTGCCCGCCGTGGCCCGAGCGCTTCGAAGAGGCCGGGGTGCGCATGCAGGTGTACTC
GCCGCTGGGCCCGCTGGGCCTGCTGCTGCCCAGGCGCTGGCGGCGCCTGCACCGCAAGCTGTGCGTGGTGGACGGCTGCG
TGCTGTACTGCGGCGGCATCAATGTGCTGGACGACCTGCACGACCCCAACCATGGCGCGCTGGAGTCTCCGCGGTTCGAC
TTCGCCGTGCGGGTGGAAGGCCGCCTCGTGGAGGAGGCCGGCGAAGCCATGGAGCAGGTCTGGTGGCGCCTGCAGGCCAC
GCGCGATGCACGCCAGCACCGGCTGGCCGACCTGATGCGCGATCTGCGCGCCGCCGCGCAGGCGCGCCAGGCGGAGCGCA
GGGCCCGGGAGGCCGCGTCCGATGGCCCTACGGCGGCGCACGGGCTGCGTGCCGGGCTGCTGCTGCGCGACAACCTGCGC
AACCGCAGCCGCATCGAGCGCGCCTACCGCCGCGCCATCGGCAACGCCCGCCACGAAGTCATCATCGCCAACGCCTACTT
CCTGCCGGGGCGCAAGCTGCGGCACGCGCTCGTGCTGGCCGCGCGCCGCGGCGTGCGCGTGCGGCTGCTGCTGCAGGGGC
GCTACGAATATTTCATGCAGTACCACGCGGCGCGGCCGGTCTATGGCGCGCTGCTGGCGGCCGGGGTGGAAATCCACGAG
TACGCGCCGAGCTTCCTGCACGCCAAGGTGGCGGTGATCGACGCGCAGGGAGAGCGCCCCTGGGCGACCGTGGGTTCGTC
CAACCTCGATCCGCTGTCCATGCTGCTGGCGCGCGAGGCGAACGTGGTGGTGGAGGACGCAGGATTCGCCCGGGTGCTGC
GGGAGCGGCTGGTGGACGCCATGGAGCACGCCGGCCGGCGGCTGGACCCGCAGGCCTGCGGGGCGCGCCCCTGGGGCCAG
CGGCTGCGCGACCGGGTGGCGTTCGCGCTCATGCGCCTCGCTCTGTGGGTGACCGGCAGCCGGTACTGA

Upstream 100 bases:

>100_bases
CGGACCACCTGCCGCTGATCGCGGAATTCCGGCTGTGACGCCGCAGGCCCCGCGTTCCGCTGCGCCGGCACCCGCGTCCG
CGCCCGCACCGCGGCGCGGC

Downstream 100 bases:

>100_bases
GGCGGCCCTGCCTATCGGGCGTTTGCTATTGATTTGGTAGCTCGATGTGGCCCGTTGGCGCCGCCAGAGCCCGCGAAACC
CTTGTCGAGCCGGGGTGGCG

Product: phospholipase D/transphosphatidylase

Products: NA

Alternate protein names: CL synthase [H]

Number of amino acids: Translated: 422; Mature: 421

Protein sequence:

>422_residues
MPRFTLRRRRAAPAPLSGGHRVALLQGSAELFAALMADMDAALSDIQFETYIFDCTGSGADIAEALIRAARRGVRVQLVV
DGVGTGRLCPPWPERFEEAGVRMQVYSPLGPLGLLLPRRWRRLHRKLCVVDGCVLYCGGINVLDDLHDPNHGALESPRFD
FAVRVEGRLVEEAGEAMEQVWWRLQATRDARQHRLADLMRDLRAAAQARQAERRAREAASDGPTAAHGLRAGLLLRDNLR
NRSRIERAYRRAIGNARHEVIIANAYFLPGRKLRHALVLAARRGVRVRLLLQGRYEYFMQYHAARPVYGALLAAGVEIHE
YAPSFLHAKVAVIDAQGERPWATVGSSNLDPLSMLLAREANVVVEDAGFARVLRERLVDAMEHAGRRLDPQACGARPWGQ
RLRDRVAFALMRLALWVTGSRY

Sequences:

>Translated_422_residues
MPRFTLRRRRAAPAPLSGGHRVALLQGSAELFAALMADMDAALSDIQFETYIFDCTGSGADIAEALIRAARRGVRVQLVV
DGVGTGRLCPPWPERFEEAGVRMQVYSPLGPLGLLLPRRWRRLHRKLCVVDGCVLYCGGINVLDDLHDPNHGALESPRFD
FAVRVEGRLVEEAGEAMEQVWWRLQATRDARQHRLADLMRDLRAAAQARQAERRAREAASDGPTAAHGLRAGLLLRDNLR
NRSRIERAYRRAIGNARHEVIIANAYFLPGRKLRHALVLAARRGVRVRLLLQGRYEYFMQYHAARPVYGALLAAGVEIHE
YAPSFLHAKVAVIDAQGERPWATVGSSNLDPLSMLLAREANVVVEDAGFARVLRERLVDAMEHAGRRLDPQACGARPWGQ
RLRDRVAFALMRLALWVTGSRY
>Mature_421_residues
PRFTLRRRRAAPAPLSGGHRVALLQGSAELFAALMADMDAALSDIQFETYIFDCTGSGADIAEALIRAARRGVRVQLVVD
GVGTGRLCPPWPERFEEAGVRMQVYSPLGPLGLLLPRRWRRLHRKLCVVDGCVLYCGGINVLDDLHDPNHGALESPRFDF
AVRVEGRLVEEAGEAMEQVWWRLQATRDARQHRLADLMRDLRAAAQARQAERRAREAASDGPTAAHGLRAGLLLRDNLRN
RSRIERAYRRAIGNARHEVIIANAYFLPGRKLRHALVLAARRGVRVRLLLQGRYEYFMQYHAARPVYGALLAAGVEIHEY
APSFLHAKVAVIDAQGERPWATVGSSNLDPLSMLLAREANVVVEDAGFARVLRERLVDAMEHAGRRLDPQACGARPWGQR
LRDRVAFALMRLALWVTGSRY

Specific function: Catalyzes, in vitro, the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol [H]

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PLD phosphodiesterase domains [H]

Homologues:

Organism=Escherichia coli, GI1787007, Length=403, Percent_Identity=33.9950372208437, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI1787502, Length=408, Percent_Identity=27.4509803921569, Blast_Score=134, Evalue=9e-33,
Organism=Escherichia coli, GI87081826, Length=427, Percent_Identity=26.463700234192, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001736 [H]

Pfam domain/function: PF00614 PLDc [H]

EC number: 2.7.8.-

Molecular weight: Translated: 47214; Mature: 47083

Theoretical pI: Translated: 10.70; Mature: 10.70

Prosite motif: PS50035 PLD ; PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRFTLRRRRAAPAPLSGGHRVALLQGSAELFAALMADMDAALSDIQFETYIFDCTGSGA
CCCCHHHHHCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCEEEEEEEEECCCCH
DIAEALIRAARRGVRVQLVVDGVGTGRLCPPWPERFEEAGVRMQVYSPLGPLGLLLPRRW
HHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHCCCEEEEECCCCHHHHHHHHHH
RRLHRKLCVVDGCVLYCGGINVLDDLHDPNHGALESPRFDFAVRVEGRLVEEAGEAMEQV
HHHHHHHHHHCCHHHEECCCHHHHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHH
WWRLQATRDARQHRLADLMRDLRAAAQARQAERRAREAASDGPTAAHGLRAGLLLRDNLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC
NRSRIERAYRRAIGNARHEVIIANAYFLPGRKLRHALVLAARRGVRVRLLLQGRYEYFMQ
HHHHHHHHHHHHHCCCCCEEEEEEEEECCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHH
YHAARPVYGALLAAGVEIHEYAPSFLHAKVAVIDAQGERPWATVGSSNLDPLSMLLAREA
HHCCCHHHHHHHHHCCHHHHHCCHHHHEEEEEEECCCCCCCEECCCCCCCHHHHHHHHCC
NVVVEDAGFARVLRERLVDAMEHAGRRLDPQACGARPWGQRLRDRVAFALMRLALWVTGS
CEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
RY
CC
>Mature Secondary Structure 
PRFTLRRRRAAPAPLSGGHRVALLQGSAELFAALMADMDAALSDIQFETYIFDCTGSGA
CCCHHHHHCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHCEEEEEEEEECCCCH
DIAEALIRAARRGVRVQLVVDGVGTGRLCPPWPERFEEAGVRMQVYSPLGPLGLLLPRRW
HHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCHHHHHHCCCEEEEECCCCHHHHHHHHHH
RRLHRKLCVVDGCVLYCGGINVLDDLHDPNHGALESPRFDFAVRVEGRLVEEAGEAMEQV
HHHHHHHHHHCCHHHEECCCHHHHHCCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHH
WWRLQATRDARQHRLADLMRDLRAAAQARQAERRAREAASDGPTAAHGLRAGLLLRDNLR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCC
NRSRIERAYRRAIGNARHEVIIANAYFLPGRKLRHALVLAARRGVRVRLLLQGRYEYFMQ
HHHHHHHHHHHHHCCCCCEEEEEEEEECCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHH
YHAARPVYGALLAAGVEIHEYAPSFLHAKVAVIDAQGERPWATVGSSNLDPLSMLLAREA
HHCCCHHHHHHHHHCCHHHHHCCHHHHEEEEEEECCCCCCCEECCCCCCCHHHHHHHHCC
NVVVEDAGFARVLRERLVDAMEHAGRRLDPQACGARPWGQRLRDRVAFALMRLALWVTGS
CEEEECCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
RY
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]