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The map label for this gene is ybbO [C]

Identifier: 120612221

GI number: 120612221

Start: 3945647

End: 3946450

Strand: Reverse

Name: ybbO [C]

Synonym: Aave_3574

Alternate gene names: 120612221

Gene position: 3946450-3945647 (Counterclockwise)

Preceding gene: 120612224

Following gene: 120612217

Centisome position: 73.73

GC content: 69.15

Gene sequence:

>804_bases
ATGGAAACGATCGACGGTAATGGGGACATGCGGCCCCTGGCGGTGGTGACGGGAGCGTCGTCCGGTATCGGCCTGGAACT
GGCACGGTGTGCCGCGCGGGGCGGTTACGACCTCGTGCTGGCGGCGGACACTCCGCTCAACGGTGCCGCCGACGCCTTGC
GCGCCGAAGGCGCGGAGGTCGAGTTCATCCAGGTGGACCTGGCCACGGCCGAAGGGCTGGAAAAGCTCTGGGCGGTCATT
GGCGACCGCATGGTGCATGCGCTCATGGCCAATGCGGGCCACGGCCTGGGCGGGGCCTTCCTGGACCAGCCTTTTGCCGA
TGTGCGCCACGTGATCGACACCAACGTGACCGGTACCGTATGGCTGGTGCAGCGCGTGGCGCAGCGCATGTGCGCGGCCG
GCCGGGGGCGCATCCTCATCACCGGTTCGATTGCCGGCTTCCTGCCCGGCAGCTTCCAGGCCGTGTACAACGGGACCAAG
GCGTTCATCGATTCGTTCGCGGCCGCGCTGCGCGACGAGCTGCAGGACTGCGGGGTGACGGTGACCTGCCTGATGCCGGG
AGTGACCGATACCGCATTCTTCGAGCGGGCGGGCATGCTGGACACGAAGTTCGGCACCCAGTCCGGCAAGTCCGATCCGG
CCGAGGTGGCGCGAACGGGCTACGCGGCGATGGAGGCCGGCGAGGCGGATGTGGTGGTGGGGCTGGGCAACAAGCTGCAG
GTGGCCCTGGCGAAGGTGACCCCCTCCCAGCTGGTCGCGGCGCAGCACCGGAAAATGGCCGAGCCCGGCACGGCCGACCG
CTAG

Upstream 100 bases:

>100_bases
GAGGCGCCCGAGCCGCTCCTGCCCGGCCCGTCTTGCATGGGACGGGGCGGTGGCGCGGGTGCCGGGCCTTTCACGCATCT
GATCGGAAAGAGGTTTCGCA

Downstream 100 bases:

>100_bases
CGGCCGCGGCAGTGCCCCCGGAGCGGCGCGGGCAGGCCGCTCAACTGCCGGCGTGCTCGAGGGTGTAGAGGCCCACGTCG
ATGTGCCCCGTGCGGAAGCC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
METIDGNGDMRPLAVVTGASSGIGLELARCAARGGYDLVLAADTPLNGAADALRAEGAEVEFIQVDLATAEGLEKLWAVI
GDRMVHALMANAGHGLGGAFLDQPFADVRHVIDTNVTGTVWLVQRVAQRMCAAGRGRILITGSIAGFLPGSFQAVYNGTK
AFIDSFAAALRDELQDCGVTVTCLMPGVTDTAFFERAGMLDTKFGTQSGKSDPAEVARTGYAAMEAGEADVVVGLGNKLQ
VALAKVTPSQLVAAQHRKMAEPGTADR

Sequences:

>Translated_267_residues
METIDGNGDMRPLAVVTGASSGIGLELARCAARGGYDLVLAADTPLNGAADALRAEGAEVEFIQVDLATAEGLEKLWAVI
GDRMVHALMANAGHGLGGAFLDQPFADVRHVIDTNVTGTVWLVQRVAQRMCAAGRGRILITGSIAGFLPGSFQAVYNGTK
AFIDSFAAALRDELQDCGVTVTCLMPGVTDTAFFERAGMLDTKFGTQSGKSDPAEVARTGYAAMEAGEADVVVGLGNKLQ
VALAKVTPSQLVAAQHRKMAEPGTADR
>Mature_267_residues
METIDGNGDMRPLAVVTGASSGIGLELARCAARGGYDLVLAADTPLNGAADALRAEGAEVEFIQVDLATAEGLEKLWAVI
GDRMVHALMANAGHGLGGAFLDQPFADVRHVIDTNVTGTVWLVQRVAQRMCAAGRGRILITGSIAGFLPGSFQAVYNGTK
AFIDSFAAALRDELQDCGVTVTCLMPGVTDTAFFERAGMLDTKFGTQSGKSDPAEVARTGYAAMEAGEADVVVGLGNKLQ
VALAKVTPSQLVAAQHRKMAEPGTADR

Specific function: Unknown

COG id: COG0300

COG function: function code R; Short-chain dehydrogenases of various substrate specificities

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI223718074, Length=194, Percent_Identity=31.9587628865979, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI7705855, Length=180, Percent_Identity=28.8888888888889, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI20149619, Length=286, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI4557649, Length=185, Percent_Identity=28.6486486486486, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1786701, Length=214, Percent_Identity=27.5700934579439, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87082160, Length=182, Percent_Identity=31.8681318681319, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1787335, Length=200, Percent_Identity=33, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788459, Length=212, Percent_Identity=28.7735849056604, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082100, Length=212, Percent_Identity=31.1320754716981, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787820, Length=205, Percent_Identity=27.8048780487805, Blast_Score=62, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319635, Length=195, Percent_Identity=27.1794871794872, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322067, Length=176, Percent_Identity=31.25, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323882, Length=190, Percent_Identity=31.0526315789474, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24640442, Length=190, Percent_Identity=31.0526315789474, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI116007236, Length=198, Percent_Identity=32.3232323232323, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24639444, Length=185, Percent_Identity=31.3513513513514, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24648944, Length=195, Percent_Identity=31.2820512820513, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21356301, Length=191, Percent_Identity=30.8900523560209, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 27739; Mature: 27739

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METIDGNGDMRPLAVVTGASSGIGLELARCAARGGYDLVLAADTPLNGAADALRAEGAEV
CCCCCCCCCCCEEEEEECCCCCCCHHHHHHHCCCCCEEEEEECCCCCHHHHHHHCCCCEE
EFIQVDLATAEGLEKLWAVIGDRMVHALMANAGHGLGGAFLDQPFADVRHVIDTNVTGTV
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHCCCCCHHH
WLVQRVAQRMCAAGRGRILITGSIAGFLPGSFQAVYNGTKAFIDSFAAALRDELQDCGVT
HHHHHHHHHHHHCCCCEEEEEECHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCEE
VTCLMPGVTDTAFFERAGMLDTKFGTQSGKSDPAEVARTGYAAMEAGEADVVVGLGNKLQ
EEEECCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCHHHHCCCCCEEEEECCCCEE
VALAKVTPSQLVAAQHRKMAEPGTADR
EEEECCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
METIDGNGDMRPLAVVTGASSGIGLELARCAARGGYDLVLAADTPLNGAADALRAEGAEV
CCCCCCCCCCCEEEEEECCCCCCCHHHHHHHCCCCCEEEEEECCCCCHHHHHHHCCCCEE
EFIQVDLATAEGLEKLWAVIGDRMVHALMANAGHGLGGAFLDQPFADVRHVIDTNVTGTV
EEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHHHCCCCCHHH
WLVQRVAQRMCAAGRGRILITGSIAGFLPGSFQAVYNGTKAFIDSFAAALRDELQDCGVT
HHHHHHHHHHHHCCCCEEEEEECHHHHCCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCEE
VTCLMPGVTDTAFFERAGMLDTKFGTQSGKSDPAEVARTGYAAMEAGEADVVVGLGNKLQ
EEEECCCCCHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHCHHHHCCCCCEEEEECCCCEE
VALAKVTPSQLVAAQHRKMAEPGTADR
EEEECCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1730672 [H]