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The map label for this gene is cfa [H]

Identifier: 120612220

GI number: 120612220

Start: 3944473

End: 3945606

Strand: Direct

Name: cfa [H]

Synonym: Aave_3573

Alternate gene names: 120612220

Gene position: 3944473-3945606 (Clockwise)

Preceding gene: 120612219

Following gene: 120612222

Centisome position: 73.69

GC content: 70.02

Gene sequence:

>1134_bases
ATGGCCTGCGGGTCGCTCTCGGTGCACCTGCCCGATGGCAGGATCCTGCATGGCGCCGGCGCAGAGCCCGGGCCGCAGGC
GGCCATGGTCCTGCACGGGTGGAAGCTCGTGTGGCGGCTGCTGGCCGGGGGCGACCTCGGCCTGGCGGAGGGATACCGCC
AGGGTGAATGGTCCACGCCGGACCTCACGGCCCTGCTGGAGTGCGGCAGCCGCAACGAGGCCCCCTGGAGCCGCGCCACC
GAAGGCGGCTGGCCCGCGCGCTGGGCCGGCAGGCTGCGCCATCTGCTGCGCTCCAACACGCGCGGCGGTAGCCGGCGCAA
CATCGCCTTCCACTACGACCTGGGCAACGACTTCTACGCGCAGTGGCTGGACCCGTCGATGCTCTACTCCAGCGCGATCT
ATCCCACGGGGACGGAATCGCTCGAGGAAGCCCAGGCCGTCAAGCTGGAACGCATCGCGCAGCACCTGGCACTCGAGCCC
GGCGACGACGTGCTGGAAATCGGCTGCGGCTGGGGCGCCCTGGCCCAGGACATGGCGCAGCGGGGTGCCCGGGTGACGGG
CATCACCCTGTCCGCGGAGCAACTGCGATTCGCCCGGGAACGCATCCGGCAGGCGGGGCTGCAGGACGCCGTGGAATTGC
GGCTGCAGGACTACCGGGACGTGCCCGGCACCTTCGACCACATCGTCTCCATCGAGATGCTGGAGGCCGTCGGCGAATCC
TACTGGCCCACCTACTTCGCCACCCTGCGCGACCGCCTGCGGCCGGGCGGGCGCGCCGTACTCCAGGTGATCACCATCGC
CGACCGCCATTTCGAGCACTACCGTTCGGGCGCGGACTTCATCCAGCGGTATATCTTCCCGGGCGGCATGCTGCCTTCGC
CTTCGGTGCTTGCCAGCCAGGCCGCGGGCGCAGGCCTGCGCATCCGCTCGAGCGAGACCTTCGGCCCCGACTACGCCAAA
ACCCTGGCGTACTGGCGCCAGCGCTTCCAGTCCGCCTGGCCGTCCATCGAGCCGCTGGGCTTCGATGAGCCGTTCCGCAG
GCTCTGGGAATACTACCTGTGCTATTGCGAAGCCGGCTTCCGCACGGGGCACATCGACGTGGGCCTCTACACCCTCGAGC
ACGCCGGCAGTTGA

Upstream 100 bases:

>100_bases
GGAATCCACCGTCCACCACCTGCCCCATGCGCGGCGATCCGCCGGCAGGCCCTGGCTGCAGCGCCCCTTCGAACTCCTGC
TGCGCCGGCTGCTCTCCTGC

Downstream 100 bases:

>100_bases
GCGGCCTGCCCGCGCCGCTCCGGGGGCACTGCCGCGGCCGCTAGCGGTCGGCCGTGCCGGGCTCGGCCATTTTCCGGTGC
TGCGCCGCGACCAGCTGGGA

Product: cyclopropane-fatty-acyl-phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MACGSLSVHLPDGRILHGAGAEPGPQAAMVLHGWKLVWRLLAGGDLGLAEGYRQGEWSTPDLTALLECGSRNEAPWSRAT
EGGWPARWAGRLRHLLRSNTRGGSRRNIAFHYDLGNDFYAQWLDPSMLYSSAIYPTGTESLEEAQAVKLERIAQHLALEP
GDDVLEIGCGWGALAQDMAQRGARVTGITLSAEQLRFARERIRQAGLQDAVELRLQDYRDVPGTFDHIVSIEMLEAVGES
YWPTYFATLRDRLRPGGRAVLQVITIADRHFEHYRSGADFIQRYIFPGGMLPSPSVLASQAAGAGLRIRSSETFGPDYAK
TLAYWRQRFQSAWPSIEPLGFDEPFRRLWEYYLCYCEAGFRTGHIDVGLYTLEHAGS

Sequences:

>Translated_377_residues
MACGSLSVHLPDGRILHGAGAEPGPQAAMVLHGWKLVWRLLAGGDLGLAEGYRQGEWSTPDLTALLECGSRNEAPWSRAT
EGGWPARWAGRLRHLLRSNTRGGSRRNIAFHYDLGNDFYAQWLDPSMLYSSAIYPTGTESLEEAQAVKLERIAQHLALEP
GDDVLEIGCGWGALAQDMAQRGARVTGITLSAEQLRFARERIRQAGLQDAVELRLQDYRDVPGTFDHIVSIEMLEAVGES
YWPTYFATLRDRLRPGGRAVLQVITIADRHFEHYRSGADFIQRYIFPGGMLPSPSVLASQAAGAGLRIRSSETFGPDYAK
TLAYWRQRFQSAWPSIEPLGFDEPFRRLWEYYLCYCEAGFRTGHIDVGLYTLEHAGS
>Mature_376_residues
ACGSLSVHLPDGRILHGAGAEPGPQAAMVLHGWKLVWRLLAGGDLGLAEGYRQGEWSTPDLTALLECGSRNEAPWSRATE
GGWPARWAGRLRHLLRSNTRGGSRRNIAFHYDLGNDFYAQWLDPSMLYSSAIYPTGTESLEEAQAVKLERIAQHLALEPG
DDVLEIGCGWGALAQDMAQRGARVTGITLSAEQLRFARERIRQAGLQDAVELRLQDYRDVPGTFDHIVSIEMLEAVGESY
WPTYFATLRDRLRPGGRAVLQVITIADRHFEHYRSGADFIQRYIFPGGMLPSPSVLASQAAGAGLRIRSSETFGPDYAKT
LAYWRQRFQSAWPSIEPLGFDEPFRRLWEYYLCYCEAGFRTGHIDVGLYTLEHAGS

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=337, Percent_Identity=38.8724035608309, Blast_Score=191, Evalue=6e-50,
Organism=Caenorhabditis elegans, GI133904226, Length=394, Percent_Identity=37.8172588832487, Blast_Score=243, Evalue=9e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 42031; Mature: 41900

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MACGSLSVHLPDGRILHGAGAEPGPQAAMVLHGWKLVWRLLAGGDLGLAEGYRQGEWSTP
CCCCCEEEECCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCC
DLTALLECGSRNEAPWSRATEGGWPARWAGRLRHLLRSNTRGGSRRNIAFHYDLGNDFYA
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHH
QWLDPSMLYSSAIYPTGTESLEEAQAVKLERIAQHLALEPGDDVLEIGCGWGALAQDMAQ
HHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHH
RGARVTGITLSAEQLRFARERIRQAGLQDAVELRLQDYRDVPGTFDHIVSIEMLEAVGES
CCCEEEEEEECHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
YWPTYFATLRDRLRPGGRAVLQVITIADRHFEHYRSGADFIQRYIFPGGMLPSPSVLASQ
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
AAGAGLRIRSSETFGPDYAKTLAYWRQRFQSAWPSIEPLGFDEPFRRLWEYYLCYCEAGF
HCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCC
RTGHIDVGLYTLEHAGS
CCCCEEEEEEEECCCCC
>Mature Secondary Structure 
ACGSLSVHLPDGRILHGAGAEPGPQAAMVLHGWKLVWRLLAGGDLGLAEGYRQGEWSTP
CCCCEEEECCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCCC
DLTALLECGSRNEAPWSRATEGGWPARWAGRLRHLLRSNTRGGSRRNIAFHYDLGNDFYA
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCHHH
QWLDPSMLYSSAIYPTGTESLEEAQAVKLERIAQHLALEPGDDVLEIGCGWGALAQDMAQ
HHCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHH
RGARVTGITLSAEQLRFARERIRQAGLQDAVELRLQDYRDVPGTFDHIVSIEMLEAVGES
CCCEEEEEEECHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCC
YWPTYFATLRDRLRPGGRAVLQVITIADRHFEHYRSGADFIQRYIFPGGMLPSPSVLASQ
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
AAGAGLRIRSSETFGPDYAKTLAYWRQRFQSAWPSIEPLGFDEPFRRLWEYYLCYCEAGF
HCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCC
RTGHIDVGLYTLEHAGS
CCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]