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The map label for this gene is atoS [C]

Identifier: 120612211

GI number: 120612211

Start: 3935879

End: 3937513

Strand: Direct

Name: atoS [C]

Synonym: Aave_3564

Alternate gene names: 120612211

Gene position: 3935879-3937513 (Clockwise)

Preceding gene: 120612202

Following gene: 120612212

Centisome position: 73.53

GC content: 67.46

Gene sequence:

>1635_bases
ATGAGCAGCGAGAAGCCCCCCATTACCGGCCAGGCGCGTCCTTTCGTCGCGGAAGGCGCTCCCAACGAGGTCGCCGAGCA
CAAGGACGACATCTTTTTCGCGGCCATCGAAACCACGCGGATGCCGATGCTGGTCACGGATCCGCGCCAGCCCGACAACC
CCATCGTGTTCTGCAACCGCGCCTTCGTCGCGATGACGGGCTACCAGCCGCAGGACATCCTCGGGCACAACTGCCGGTTC
CTCCAGGGCCCCGCCACCGACCGCAACACCGTCGCGGCCCTGCGCGAAGCCATCGATCAGCGGCGCGAGATCTCGCTGGA
GCTGCTCAACTACCGCAAGGACGGCTCCACGTTCTGGAACGCGCTGTTCATCTCGCCGGTCTACAACGCGCGTGGCGAGC
TCGTCTATTTCTTCGCTTCGCAGCTCGACGTGAGCCGGCGCCGGGACGCCGAGGAAGCGCTGTCGCAGGCGCAGAAGATG
GAGGCGCTCGGCCAGCTGACCGGTGGCATCTCGCACGACTTCAACAACCTGCTGCAGGTCATGTCCGGCCACCTGGACGT
GATGCGCGTGCGCAACCGCAGCCAGAAGCTCGGTCGCGAGGACATCGACCGCTCCATCGACAGCATCCGCAGCGCCGTCG
GCAAGGCCTCCACGCTCACACAGCAACTGCTGGCGTTCTCCCGCAAGCAGAAGCTCCAGGGCCGGGTCGTCAGCCTGAAT
GCGCTGGCCACGGGCATGGCCTCGCTGGCCGAACGCACGCTCGGCGAAGCGATCGAGATCGACTACGTGCTCGGTGACGA
CGTACCCAACTGCGAACTGGACACCACCCAACTGGAAGTGGCGGTGCTCAACCTGCTCCTCAACTCCCGCGATGCCATGC
CCAACGGCGGCCGCATCCGGGTCGAGACGCGCGGCATCGAGCTGCACGCCCAGGACGGCCATGCCTTCTCCGGCCTGCCC
CCGGGCCGCTATGCCACCCTGTCGGTGACCGATACCGGCTCGGGCATCCCGGCCGACATGGTGCCGCGCGTGATGGACCC
GTTCTTCACCACCAAGGAAGAAGGCAAGGGTACCGGCCTGGGGCTGTCCATGGTGTACGGTTTCGCCAAGCAATCGGGCG
GTGCCGTCACGATCTATTCGGAAGTCGGCGTGGGCACCACGGTGCGCATGTACTTCCCGGCCGTGCACGGGCGCACGCAC
CCCGAACTGGTGGAATCGCTCGCCCCCCATGCGCGCGGCGGCACGGAAACCGTGCTGGTCGTGGACGACCGCGTCGAGGT
GGCCGACCTCGCCCAGGCCATGCTGGAAGGCCTGGGGTACACGGTCCACGTGGCGCACAGCGCGCACGCGGCCCTCAAGC
TCGTGCGCTCCCTGGAGCCCTCCGCGCTTCCGCACCTGCTCTTCACCGACGTGGTGATGCCCGGCGGCCTGAACGGCTAC
GAGCTGGCCCGCGAGATGCGCAAGACGGTGGCCGGCATCCATATCCTGCTGACCACGGGCTTCGACCGCGACATGGGCAG
CCTCGCCAACGTCGCGCCCACCGAATTCGAGATCCTGAAGAAGCCCTACCGGCTGGCGGATCTCGCACGGCGCGTGCGCA
TGGTGCTCGACGGCGCCACCGGCACCAAGACCTGA

Upstream 100 bases:

>100_bases
AGGACGCCACCGCCACCTGCACCGCACGGCGCCTGCGCCTACAGGCCGGCCGCCCCGGGGGAAATGTCCAGGCCGCTGGT
TTGTCCGTATAGTCCACCTG

Downstream 100 bases:

>100_bases
ACCCGCGGCGGCAGCCGCGGGACGCCGGCGCGCCGGCGTCCTGCAATCCAAACAGGAGCCCGCCGCGTACAGGCCGGAAC
CAGGCGGGCCATCCGGCACG

Product: histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 544; Mature: 543

Protein sequence:

>544_residues
MSSEKPPITGQARPFVAEGAPNEVAEHKDDIFFAAIETTRMPMLVTDPRQPDNPIVFCNRAFVAMTGYQPQDILGHNCRF
LQGPATDRNTVAALREAIDQRREISLELLNYRKDGSTFWNALFISPVYNARGELVYFFASQLDVSRRRDAEEALSQAQKM
EALGQLTGGISHDFNNLLQVMSGHLDVMRVRNRSQKLGREDIDRSIDSIRSAVGKASTLTQQLLAFSRKQKLQGRVVSLN
ALATGMASLAERTLGEAIEIDYVLGDDVPNCELDTTQLEVAVLNLLLNSRDAMPNGGRIRVETRGIELHAQDGHAFSGLP
PGRYATLSVTDTGSGIPADMVPRVMDPFFTTKEEGKGTGLGLSMVYGFAKQSGGAVTIYSEVGVGTTVRMYFPAVHGRTH
PELVESLAPHARGGTETVLVVDDRVEVADLAQAMLEGLGYTVHVAHSAHAALKLVRSLEPSALPHLLFTDVVMPGGLNGY
ELAREMRKTVAGIHILLTTGFDRDMGSLANVAPTEFEILKKPYRLADLARRVRMVLDGATGTKT

Sequences:

>Translated_544_residues
MSSEKPPITGQARPFVAEGAPNEVAEHKDDIFFAAIETTRMPMLVTDPRQPDNPIVFCNRAFVAMTGYQPQDILGHNCRF
LQGPATDRNTVAALREAIDQRREISLELLNYRKDGSTFWNALFISPVYNARGELVYFFASQLDVSRRRDAEEALSQAQKM
EALGQLTGGISHDFNNLLQVMSGHLDVMRVRNRSQKLGREDIDRSIDSIRSAVGKASTLTQQLLAFSRKQKLQGRVVSLN
ALATGMASLAERTLGEAIEIDYVLGDDVPNCELDTTQLEVAVLNLLLNSRDAMPNGGRIRVETRGIELHAQDGHAFSGLP
PGRYATLSVTDTGSGIPADMVPRVMDPFFTTKEEGKGTGLGLSMVYGFAKQSGGAVTIYSEVGVGTTVRMYFPAVHGRTH
PELVESLAPHARGGTETVLVVDDRVEVADLAQAMLEGLGYTVHVAHSAHAALKLVRSLEPSALPHLLFTDVVMPGGLNGY
ELAREMRKTVAGIHILLTTGFDRDMGSLANVAPTEFEILKKPYRLADLARRVRMVLDGATGTKT
>Mature_543_residues
SSEKPPITGQARPFVAEGAPNEVAEHKDDIFFAAIETTRMPMLVTDPRQPDNPIVFCNRAFVAMTGYQPQDILGHNCRFL
QGPATDRNTVAALREAIDQRREISLELLNYRKDGSTFWNALFISPVYNARGELVYFFASQLDVSRRRDAEEALSQAQKME
ALGQLTGGISHDFNNLLQVMSGHLDVMRVRNRSQKLGREDIDRSIDSIRSAVGKASTLTQQLLAFSRKQKLQGRVVSLNA
LATGMASLAERTLGEAIEIDYVLGDDVPNCELDTTQLEVAVLNLLLNSRDAMPNGGRIRVETRGIELHAQDGHAFSGLPP
GRYATLSVTDTGSGIPADMVPRVMDPFFTTKEEGKGTGLGLSMVYGFAKQSGGAVTIYSEVGVGTTVRMYFPAVHGRTHP
ELVESLAPHARGGTETVLVVDDRVEVADLAQAMLEGLGYTVHVAHSAHAALKLVRSLEPSALPHLLFTDVVMPGGLNGYE
LAREMRKTVAGIHILLTTGFDRDMGSLANVAPTEFEILKKPYRLADLARRVRMVLDGATGTKT

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Homo sapiens, GI38569493, Length=276, Percent_Identity=24.6376811594203, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI6912446, Length=95, Percent_Identity=37.8947368421053, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI27886667, Length=275, Percent_Identity=25.0909090909091, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI1788549, Length=351, Percent_Identity=27.0655270655271, Blast_Score=112, Evalue=6e-26,
Organism=Escherichia coli, GI1790436, Length=274, Percent_Identity=25.9124087591241, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI145693157, Length=284, Percent_Identity=25.3521126760563, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI48994928, Length=174, Percent_Identity=30.4597701149425, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17136946, Length=101, Percent_Identity=34.6534653465347, Blast_Score=79, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 59341; Mature: 59209

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSEKPPITGQARPFVAEGAPNEVAEHKDDIFFAAIETTRMPMLVTDPRQPDNPIVFCNR
CCCCCCCCCCCCCCEEECCCCHHHHHCCCCEEEEEEECCCCCEEEECCCCCCCCEEEECC
AFVAMTGYQPQDILGHNCRFLQGPATDRNTVAALREAIDQRREISLELLNYRKDGSTFWN
EEEEEECCCCHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEH
ALFISPVYNARGELVYFFASQLDVSRRRDAEEALSQAQKMEALGQLTGGISHDFNNLLQV
HEEECCCCCCCCCEEEEEEHHHCHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
MSGHLDVMRVRNRSQKLGREDIDRSIDSIRSAVGKASTLTQQLLAFSRKQKLQGRVVSLN
HHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCEEEEHH
ALATGMASLAERTLGEAIEIDYVLGDDVPNCELDTTQLEVAVLNLLLNSRDAMPNGGRIR
HHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEE
VETRGIELHAQDGHAFSGLPPGRYATLSVTDTGSGIPADMVPRVMDPFFTTKEEGKGTGL
EEECCEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCC
GLSMVYGFAKQSGGAVTIYSEVGVGTTVRMYFPAVHGRTHPELVESLAPHARGGTETVLV
HHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECHHCCCCCHHHHHHHCCCCCCCCCEEEE
VDDRVEVADLAQAMLEGLGYTVHVAHSAHAALKLVRSLEPSALPHLLFTDVVMPGGLNGY
EECCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHH
ELAREMRKTVAGIHILLTTGFDRDMGSLANVAPTEFEILKKPYRLADLARRVRMVLDGAT
HHHHHHHHHHCCEEEEEEECCCCCHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHCCCC
GTKT
CCCC
>Mature Secondary Structure 
SSEKPPITGQARPFVAEGAPNEVAEHKDDIFFAAIETTRMPMLVTDPRQPDNPIVFCNR
CCCCCCCCCCCCCEEECCCCHHHHHCCCCEEEEEEECCCCCEEEECCCCCCCCEEEECC
AFVAMTGYQPQDILGHNCRFLQGPATDRNTVAALREAIDQRREISLELLNYRKDGSTFWN
EEEEEECCCCHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEH
ALFISPVYNARGELVYFFASQLDVSRRRDAEEALSQAQKMEALGQLTGGISHDFNNLLQV
HEEECCCCCCCCCEEEEEEHHHCHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
MSGHLDVMRVRNRSQKLGREDIDRSIDSIRSAVGKASTLTQQLLAFSRKQKLQGRVVSLN
HHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCEEEEHH
ALATGMASLAERTLGEAIEIDYVLGDDVPNCELDTTQLEVAVLNLLLNSRDAMPNGGRIR
HHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEE
VETRGIELHAQDGHAFSGLPPGRYATLSVTDTGSGIPADMVPRVMDPFFTTKEEGKGTGL
EEECCEEEEECCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCCCC
GLSMVYGFAKQSGGAVTIYSEVGVGTTVRMYFPAVHGRTHPELVESLAPHARGGTETVLV
HHHHHHHHHHCCCCEEEEEECCCCCEEEEEEECHHCCCCCHHHHHHHCCCCCCCCCEEEE
VDDRVEVADLAQAMLEGLGYTVHVAHSAHAALKLVRSLEPSALPHLLFTDVVMPGGLNGY
EECCCCHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCHH
ELAREMRKTVAGIHILLTTGFDRDMGSLANVAPTEFEILKKPYRLADLARRVRMVLDGAT
HHHHHHHHHHCCEEEEEEECCCCCHHHHHCCCCCHHHHHHCCHHHHHHHHHHHHHHCCCC
GTKT
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA