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The map label for this gene is cysU [H]

Identifier: 120612108

GI number: 120612108

Start: 3818051

End: 3818875

Strand: Direct

Name: cysU [H]

Synonym: Aave_3455

Alternate gene names: 120612108

Gene position: 3818051-3818875 (Clockwise)

Preceding gene: 120612107

Following gene: 120612109

Centisome position: 71.33

GC content: 71.15

Gene sequence:

>825_bases
ATGACGGCACGCCACGGCGGCTTCGCTCCTTCGCGCGCCCTGCTGGCCGCGTGCGCCGCGCCGGCCGTGGCGTTCTTCGC
GGCCTTCTGGCTGCTGCCCACGGCCCTGCTGGTGGCGCTGCCGGCGCGCCAGGGCTGGGCGACGTATTTCGCGGTGCTGA
CGAACGGCCGCTACCTGCAGAGCCTGCTGCAGACGCTGGGTCTGTCGCTGGCCGTGACGCTCGCCACGCTGATGCTCGGC
GCCCTGGTGGGCATCACGCTGGCGCGCCAGCGCTTTCCCGGGCGGCAGCTGCTGCTGTCGCTGCTGACGCTGCCGCTGTC
CTTTCCCGGCGTGATCGTGGGATTCTTCATGATTTTGCTGGGCGGTCGCCAGGGCACGCTGGCGGGCCTGACGCAGGCGC
TGGGCTGGGGCCGGATCACCTTCGCCTATGGGCTGGTGGGCCTGTTCCTGGCCTACCTGTACTTTTCGCTGCCGCGCGCC
ATCGCCACCTACACGGCGGCGGCCGGCGCCATGGACGCGCAGCTCGAAGAAGCCGCGCGCTCGCTCGGCGCCTCGCGCTG
GCGCGTGGCGCGCGACGTGTGGATGCCGGCGCTCGCGCCCACCACGCTGGCCTGCGGCGCGATCGTGTTCGCCACGGCCA
TGGGCGCCTTCGGCACGGCGTTCACGCTGTCGGCGAAGTTCGAGGTGCTGCCCATCACCATCTACGACGAATTCACCAAC
TACGCCAACTTCGCGCTGGCAGCCAGCCTGTCGATCGCGCTGGGCCTGATCACCTGGCTGGTGCTCTGGGTGTCCCGCCG
CTGGGCCGGCACGTCCGCGTTCTAA

Upstream 100 bases:

>100_bases
TCCTGCCCGCCAGCGAATATGCCCGCGCGAAGACGGTGGACTACGGCCGCATGGCCGCGGTGCAGAAGGCGTTCTCCGAC
CGCTACCTGCGGGACGTGAA

Downstream 100 bases:

>100_bases
GGAATCTCCATGCGCAACGCACGACAGGCACCCTGGGCGCTGATCGCCCTCACCGCGCTGGTGACGCTCTTCATGGCCGC
GCCCATCGCCCTGTCGGTGA

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MTARHGGFAPSRALLAACAAPAVAFFAAFWLLPTALLVALPARQGWATYFAVLTNGRYLQSLLQTLGLSLAVTLATLMLG
ALVGITLARQRFPGRQLLLSLLTLPLSFPGVIVGFFMILLGGRQGTLAGLTQALGWGRITFAYGLVGLFLAYLYFSLPRA
IATYTAAAGAMDAQLEEAARSLGASRWRVARDVWMPALAPTTLACGAIVFATAMGAFGTAFTLSAKFEVLPITIYDEFTN
YANFALAASLSIALGLITWLVLWVSRRWAGTSAF

Sequences:

>Translated_274_residues
MTARHGGFAPSRALLAACAAPAVAFFAAFWLLPTALLVALPARQGWATYFAVLTNGRYLQSLLQTLGLSLAVTLATLMLG
ALVGITLARQRFPGRQLLLSLLTLPLSFPGVIVGFFMILLGGRQGTLAGLTQALGWGRITFAYGLVGLFLAYLYFSLPRA
IATYTAAAGAMDAQLEEAARSLGASRWRVARDVWMPALAPTTLACGAIVFATAMGAFGTAFTLSAKFEVLPITIYDEFTN
YANFALAASLSIALGLITWLVLWVSRRWAGTSAF
>Mature_273_residues
TARHGGFAPSRALLAACAAPAVAFFAAFWLLPTALLVALPARQGWATYFAVLTNGRYLQSLLQTLGLSLAVTLATLMLGA
LVGITLARQRFPGRQLLLSLLTLPLSFPGVIVGFFMILLGGRQGTLAGLTQALGWGRITFAYGLVGLFLAYLYFSLPRAI
ATYTAAAGAMDAQLEEAARSLGASRWRVARDVWMPALAPTTLACGAIVFATAMGAFGTAFTLSAKFEVLPITIYDEFTNY
ANFALAASLSIALGLITWLVLWVSRRWAGTSAF

Specific function: Part of the ABC transporter complex CysAWTP (TC 3.A.1.6.1) involved in sulfate/thiosulfate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0555

COG function: function code O; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788764, Length=214, Percent_Identity=29.4392523364486, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1786980, Length=223, Percent_Identity=32.7354260089686, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1786254, Length=168, Percent_Identity=31.547619047619, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI87082099, Length=207, Percent_Identity=27.0531400966184, Blast_Score=65, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515
- InterPro:   IPR011865
- InterPro:   IPR005667 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29125; Mature: 28994

Theoretical pI: Translated: 10.68; Mature: 10.68

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTARHGGFAPSRALLAACAAPAVAFFAAFWLLPTALLVALPARQGWATYFAVLTNGRYLQ
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHH
SLLQTLGLSLAVTLATLMLGALVGITLARQRFPGRQLLLSLLTLPLSFPGVIVGFFMILL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHH
GGRQGTLAGLTQALGWGRITFAYGLVGLFLAYLYFSLPRAIATYTAAAGAMDAQLEEAAR
CCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLGASRWRVARDVWMPALAPTTLACGAIVFATAMGAFGTAFTLSAKFEVLPITIYDEFTN
HHCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECEEEEEEEEEHHHHH
YANFALAASLSIALGLITWLVLWVSRRWAGTSAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TARHGGFAPSRALLAACAAPAVAFFAAFWLLPTALLVALPARQGWATYFAVLTNGRYLQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHH
SLLQTLGLSLAVTLATLMLGALVGITLARQRFPGRQLLLSLLTLPLSFPGVIVGFFMILL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHH
GGRQGTLAGLTQALGWGRITFAYGLVGLFLAYLYFSLPRAIATYTAAAGAMDAQLEEAAR
CCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLGASRWRVARDVWMPALAPTTLACGAIVFATAMGAFGTAFTLSAKFEVLPITIYDEFTN
HHCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEEEEECEEEEEEEEEHHHHH
YANFALAASLSIALGLITWLVLWVSRRWAGTSAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2188958; 9205837; 9278503; 2188959 [H]