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The map label for this gene is chiA1 [H]

Identifier: 120612095

GI number: 120612095

Start: 3801584

End: 3802828

Strand: Direct

Name: chiA1 [H]

Synonym: Aave_3442

Alternate gene names: 120612095

Gene position: 3801584-3802828 (Clockwise)

Preceding gene: 120612094

Following gene: 120612096

Centisome position: 71.02

GC content: 71.16

Gene sequence:

>1245_bases
ATGTCCGCCCACGCCCACGCCTACGCCCACGCGGCAGCGCCCGCACGCGAAATGGTGGGCTACTTCACGTCCTGGGGCAT
CTATGCCCGCGGCTACACCGCGAGAAGCCTGGCCTCCCAGGGCGCCCTGCCCCGCATCACCACGCTGAACTATGCGTTCG
GCAGCGTGGCGCCCGCCAGCGCGGACGGCAGCGGCCCGGTGGGCTGTCGGCTCGGCGACGCGTGGGCCGACGTGGAGCGT
CCCTGGACGGCCGAGGAAAGCGTGGACGGCACGGCGGTGGACGACACCCAGCCGCTGCGCGGCAACTTCCAGCAGCTGCG
CGCGCTCAAGCGCCTGCGGCCCGGGCTGAAGGTGCTGGTCTCGCTGGGGGGATGGAACGGATCGAAGTGGTTCTCCGACG
CGGCGCTCACGCCCGCGTCGCGCAGCGCGTTCGTGAAGTCGTGCGTCGATCTCTTCATCCGCGGCCGCACCGGAGGGGAA
ACCGAAGGCGACGGCCCGGCCGCGGGCGTGTTCGACGGCATCGACATCGACTGGGAGCACGTCGCCGCCGAGGCTGCACC
GGGCAATATCGTGCGGCCAGAGGATACGGCGAACTTCACGCTGCTGCTGCAGGAATTCCGCCGGCAGCTCGATGCGATCG
ACCCGGCGCTGCGCCTGACCATCGCGGCCCCCGCGGGCCCGCAGAACAGCGCGAAGATCGAGCTCGCGGCCGTGGCGAAG
ACGGTGGATTTCATCAACCTGATGGCCTACGACCTCCATGTTTCCCCGGAGCGCCGCACCAACCACCAGGCCGCGCTCGC
ACCCAGCCCGCGCGACCCCGACCGGGCAAAGGATCTCTCGGTGGTGGAAGCCGTCGGCCGGTACCTGCAGGCCGGCGTGC
CGCGCAGCAAGCTCGTGGTCGGCGCACCGCTGTACTCGCAGGGATGGAGCGGCGTGAATCCGGCTGGCAACGGCCTCTAC
CAGCCGGCCACGGGGCCCGCGCAGGGCACCTACGAGGCCGGCGTGGATGATTTCAAGACCGTGCGCGCCAAGCCCGGTTT
CACGCGCCACCGGGACGCGTGGTCGCGCGCGGCCTGGCTTTTCGACGGCAGCACGTTCTGGACCTTCGACGACGAACAGG
TCGTGCGCGAGAAGGCGCGCACCGTGCGGGCCGCGGGCCTGCGCGGCATGATGTTCTGGGAGCTTTCCGGCGATGGTGGC
GAGCTGGTGCGCGCGGCGGGAGAGGAGCTGTCCACGGGCCGCTGA

Upstream 100 bases:

>100_bases
CTGGACCCGCCCCCTGGGCATCGCCTGCCTGGCCTTCCTGGCCGCCCCTGCCTGGAGCGGCACGGCCGCGCCGGACGCCG
GGCAACAGCCGCGCTTCGCC

Downstream 100 bases:

>100_bases
AACCCGCGGGACGCGCCGTGGAAGGCGAATCCGGGATAATCCCGTGATTCCCTGCAGCCGGGCCGAGCGCCCGGCTCTCT
ATTTTCAGCACGAGACATGA

Product: glycosyl hydrolase family chitinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MSAHAHAYAHAAAPAREMVGYFTSWGIYARGYTARSLASQGALPRITTLNYAFGSVAPASADGSGPVGCRLGDAWADVER
PWTAEESVDGTAVDDTQPLRGNFQQLRALKRLRPGLKVLVSLGGWNGSKWFSDAALTPASRSAFVKSCVDLFIRGRTGGE
TEGDGPAAGVFDGIDIDWEHVAAEAAPGNIVRPEDTANFTLLLQEFRRQLDAIDPALRLTIAAPAGPQNSAKIELAAVAK
TVDFINLMAYDLHVSPERRTNHQAALAPSPRDPDRAKDLSVVEAVGRYLQAGVPRSKLVVGAPLYSQGWSGVNPAGNGLY
QPATGPAQGTYEAGVDDFKTVRAKPGFTRHRDAWSRAAWLFDGSTFWTFDDEQVVREKARTVRAAGLRGMMFWELSGDGG
ELVRAAGEELSTGR

Sequences:

>Translated_414_residues
MSAHAHAYAHAAAPAREMVGYFTSWGIYARGYTARSLASQGALPRITTLNYAFGSVAPASADGSGPVGCRLGDAWADVER
PWTAEESVDGTAVDDTQPLRGNFQQLRALKRLRPGLKVLVSLGGWNGSKWFSDAALTPASRSAFVKSCVDLFIRGRTGGE
TEGDGPAAGVFDGIDIDWEHVAAEAAPGNIVRPEDTANFTLLLQEFRRQLDAIDPALRLTIAAPAGPQNSAKIELAAVAK
TVDFINLMAYDLHVSPERRTNHQAALAPSPRDPDRAKDLSVVEAVGRYLQAGVPRSKLVVGAPLYSQGWSGVNPAGNGLY
QPATGPAQGTYEAGVDDFKTVRAKPGFTRHRDAWSRAAWLFDGSTFWTFDDEQVVREKARTVRAAGLRGMMFWELSGDGG
ELVRAAGEELSTGR
>Mature_413_residues
SAHAHAYAHAAAPAREMVGYFTSWGIYARGYTARSLASQGALPRITTLNYAFGSVAPASADGSGPVGCRLGDAWADVERP
WTAEESVDGTAVDDTQPLRGNFQQLRALKRLRPGLKVLVSLGGWNGSKWFSDAALTPASRSAFVKSCVDLFIRGRTGGET
EGDGPAAGVFDGIDIDWEHVAAEAAPGNIVRPEDTANFTLLLQEFRRQLDAIDPALRLTIAAPAGPQNSAKIELAAVAKT
VDFINLMAYDLHVSPERRTNHQAALAPSPRDPDRAKDLSVVEAVGRYLQAGVPRSKLVVGAPLYSQGWSGVNPAGNGLYQ
PATGPAQGTYEAGVDDFKTVRAKPGFTRHRDAWSRAAWLFDGSTFWTFDDEQVVREKARTVRAAGLRGMMFWELSGDGGE
LVRAAGEELSTGR

Specific function: Unknown

COG id: COG3325

COG function: function code G; Chitinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 fibronectin type-III domains [H]

Homologues:

Organism=Homo sapiens, GI4502809, Length=394, Percent_Identity=29.4416243654822, Blast_Score=146, Evalue=4e-35,
Organism=Homo sapiens, GI133893286, Length=309, Percent_Identity=29.126213592233, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI144226251, Length=401, Percent_Identity=28.1795511221945, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI42542398, Length=274, Percent_Identity=28.4671532846715, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI68533260, Length=315, Percent_Identity=27.9365079365079, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI58386720, Length=400, Percent_Identity=26, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI68533255, Length=315, Percent_Identity=27.9365079365079, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI68533253, Length=315, Percent_Identity=27.9365079365079, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17551250, Length=393, Percent_Identity=28.7531806615776, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17563680, Length=405, Percent_Identity=25.9259259259259, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17559362, Length=403, Percent_Identity=24.0694789081886, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71995504, Length=345, Percent_Identity=23.768115942029, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6320579, Length=414, Percent_Identity=22.7053140096618, Blast_Score=80, Evalue=6e-16,
Organism=Drosophila melanogaster, GI221330815, Length=394, Percent_Identity=30.7106598984772, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI161077700, Length=416, Percent_Identity=28.6057692307692, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI221329807, Length=416, Percent_Identity=28.6057692307692, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI45550474, Length=397, Percent_Identity=26.9521410579345, Blast_Score=119, Evalue=4e-27,
Organism=Drosophila melanogaster, GI116007452, Length=393, Percent_Identity=26.972010178117, Blast_Score=106, Evalue=2e-23,
Organism=Drosophila melanogaster, GI22024049, Length=313, Percent_Identity=29.073482428115, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24655584, Length=292, Percent_Identity=27.7397260273973, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI28573679, Length=312, Percent_Identity=30.7692307692308, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21358195, Length=402, Percent_Identity=23.134328358209, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24640248, Length=323, Percent_Identity=24.4582043343653, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003610
- InterPro:   IPR011583
- InterPro:   IPR008957
- InterPro:   IPR003961
- InterPro:   IPR001223
- InterPro:   IPR001579
- InterPro:   IPR017853
- InterPro:   IPR013781
- InterPro:   IPR013783 [H]

Pfam domain/function: PF02839 CBM_5_12; PF00041 fn3; PF00704 Glyco_hydro_18 [H]

EC number: =3.2.1.14 [H]

Molecular weight: Translated: 44370; Mature: 44239

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: PS01095 CHITINASE_18

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAHAHAYAHAAAPAREMVGYFTSWGIYARGYTARSLASQGALPRITTLNYAFGSVAPAS
CCCCCHHHHHHHCCHHHHHHHHHHCCCEECCCHHHHHHHCCCCCEEEEECCCCCCCCCCC
ADGSGPVGCRLGDAWADVERPWTAEESVDGTAVDDTQPLRGNFQQLRALKRLRPGLKVLV
CCCCCCCCEEECCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEE
SLGGWNGSKWFSDAALTPASRSAFVKSCVDLFIRGRTGGETEGDGPAAGVFDGIDIDWEH
EECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCHHH
VAAEAAPGNIVRPEDTANFTLLLQEFRRQLDAIDPALRLTIAAPAGPQNSAKIELAAVAK
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEHHHHHH
TVDFINLMAYDLHVSPERRTNHQAALAPSPRDPDRAKDLSVVEAVGRYLQAGVPRSKLVV
HHHHHHHHEEEEECCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHEEE
GAPLYSQGWSGVNPAGNGLYQPATGPAQGTYEAGVDDFKTVRAKPGFTRHRDAWSRAAWL
ECCHHHCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHHHCCCCCCHHHHHHHHEEEE
FDGSTFWTFDDEQVVREKARTVRAAGLRGMMFWELSGDGGELVRAAGEELSTGR
ECCCEEEEECHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SAHAHAYAHAAAPAREMVGYFTSWGIYARGYTARSLASQGALPRITTLNYAFGSVAPAS
CCCCHHHHHHHCCHHHHHHHHHHCCCEECCCHHHHHHHCCCCCEEEEECCCCCCCCCCC
ADGSGPVGCRLGDAWADVERPWTAEESVDGTAVDDTQPLRGNFQQLRALKRLRPGLKVLV
CCCCCCCCEEECCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEE
SLGGWNGSKWFSDAALTPASRSAFVKSCVDLFIRGRTGGETEGDGPAAGVFDGIDIDWEH
EECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCHHH
VAAEAAPGNIVRPEDTANFTLLLQEFRRQLDAIDPALRLTIAAPAGPQNSAKIELAAVAK
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCEEEHHHHHH
TVDFINLMAYDLHVSPERRTNHQAALAPSPRDPDRAKDLSVVEAVGRYLQAGVPRSKLVV
HHHHHHHHEEEEECCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHEEE
GAPLYSQGWSGVNPAGNGLYQPATGPAQGTYEAGVDDFKTVRAKPGFTRHRDAWSRAAWL
ECCHHHCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHHHCCCCCCHHHHHHHHEEEE
FDGSTFWTFDDEQVVREKARTVRAAGLRGMMFWELSGDGGELVRAAGEELSTGR
ECCCEEEEECHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2203782; 8103047 [H]