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The map label for this gene is acdA [H]

Identifier: 120612093

GI number: 120612093

Start: 3798445

End: 3799560

Strand: Direct

Name: acdA [H]

Synonym: Aave_3440

Alternate gene names: 120612093

Gene position: 3798445-3799560 (Clockwise)

Preceding gene: 120612092

Following gene: 120612094

Centisome position: 70.96

GC content: 70.7

Gene sequence:

>1116_bases
ATGGATTTTGATTTTTCTGAAGACCAGCAATCGTTGCGCGATGCGGTGCGGCGCTGGGTGGACAAGGGCTACACGTTCGA
GCGGCGCCGCGGCATCGTGGCGGCGGGCGGGTTCGACCGTGCGGCGTACGGCGAGCTGGCGGAGCTGGGCCTGACGGCAC
TGACGGTGCCGGAGGCGCACGACGGGCTGGGCCAGGGCGCGGTGGATGCCATGGTGGCGATGGAGGAGCTGGGCCGCGGC
ATCGTGCTGGAGCCGCTGGCGCAGACCTTCGTGGCCAGCGGCATGCTGGCGCAGTGCGCACCCGAGGCGGTGCAGGCCGC
GTGGCTGCCGCGCATCGCGAGTGGCGAGGCACTGGTGGTGCTGGCGCACCAGGAGCGCAAGGCACGCTACCGGCTGGACG
TTTGCGAGGCCCAGGCCACCGGTTCGGGCGACAGCGCCACGGTGACGGGCACCAAGAGCCTCGTGCCCGCGGGCGACCAG
GCCGATGCGTTCCTGGTGCCGGCACAGCACCAGGGCCGCGTGGCCCTTTTCCTGGTCGAGCGCGGCGCGCAGGGCGTGGC
CACGCGCGGGTACGTGACGCAGGACGGCAGCCGCGCGGCGGAGGTCCAGTTCGACAACGCGCCGGCCACGCTGGTCGCCG
AGGACGGGCTCGCGGCGCTGGAACTCGCGGTGGACATCGGCATCGCCGCGGCGTGCGCCGAGGCCGTGGGCGTGATGGAC
CAGACCGTGGCGCTCACCGTGGACTACATGAACCAGCGCAAGCAGTTCGGCGTGCCGATCGCCACCTTCCAGGCGCTGCG
CCACCGCGTGGCCGACATGAAGATGCAGCTGGAGCTGGCGCGCTCGATGAGCTATTACGCCAGCCTGAAGCTCGGCGCCC
CCGCCGAGGAGCGCCGCCGCGCCCTGTCGCGCGCGAAGGTGCAGCTCGGGCAGTCGATGCGCTTCGTGGGCCAGCAGTCC
GTGCAGTTGCATGGCGGCATCGGCGTGACCGATGAATACATCGGCAGCCACTACTTCAAGAAGCTCACGCAACTGGAAAT
GACCTGGGGCGATACGCTGCACCACCTGGGCGAGGTGTCGGCGCGCATGCAGGACACGGCGGGCGTGTTCGCCTGA

Upstream 100 bases:

>100_bases
CCCCCAGGCCCCCTCCGCGAGGGGGCTCCAGCATGAGCTTCGCTGATCTTTGAAGGGGGGCGTGCAAGCGCCCCGCCCTG
AACGGCTTTTGGAGACGAAC

Downstream 100 bases:

>100_bases
CCCGGGCGACAACGCGACCGTCTGGGCGCGGTAACACGAACCCCGCGACGGAGGGGTAGGCAGGGCGGGAACTCTGTGTT
CAAGTGCGAGGTTCATCCGA

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MDFDFSEDQQSLRDAVRRWVDKGYTFERRRGIVAAGGFDRAAYGELAELGLTALTVPEAHDGLGQGAVDAMVAMEELGRG
IVLEPLAQTFVASGMLAQCAPEAVQAAWLPRIASGEALVVLAHQERKARYRLDVCEAQATGSGDSATVTGTKSLVPAGDQ
ADAFLVPAQHQGRVALFLVERGAQGVATRGYVTQDGSRAAEVQFDNAPATLVAEDGLAALELAVDIGIAAACAEAVGVMD
QTVALTVDYMNQRKQFGVPIATFQALRHRVADMKMQLELARSMSYYASLKLGAPAEERRRALSRAKVQLGQSMRFVGQQS
VQLHGGIGVTDEYIGSHYFKKLTQLEMTWGDTLHHLGEVSARMQDTAGVFA

Sequences:

>Translated_371_residues
MDFDFSEDQQSLRDAVRRWVDKGYTFERRRGIVAAGGFDRAAYGELAELGLTALTVPEAHDGLGQGAVDAMVAMEELGRG
IVLEPLAQTFVASGMLAQCAPEAVQAAWLPRIASGEALVVLAHQERKARYRLDVCEAQATGSGDSATVTGTKSLVPAGDQ
ADAFLVPAQHQGRVALFLVERGAQGVATRGYVTQDGSRAAEVQFDNAPATLVAEDGLAALELAVDIGIAAACAEAVGVMD
QTVALTVDYMNQRKQFGVPIATFQALRHRVADMKMQLELARSMSYYASLKLGAPAEERRRALSRAKVQLGQSMRFVGQQS
VQLHGGIGVTDEYIGSHYFKKLTQLEMTWGDTLHHLGEVSARMQDTAGVFA
>Mature_371_residues
MDFDFSEDQQSLRDAVRRWVDKGYTFERRRGIVAAGGFDRAAYGELAELGLTALTVPEAHDGLGQGAVDAMVAMEELGRG
IVLEPLAQTFVASGMLAQCAPEAVQAAWLPRIASGEALVVLAHQERKARYRLDVCEAQATGSGDSATVTGTKSLVPAGDQ
ADAFLVPAQHQGRVALFLVERGAQGVATRGYVTQDGSRAAEVQFDNAPATLVAEDGLAALELAVDIGIAAACAEAVGVMD
QTVALTVDYMNQRKQFGVPIATFQALRHRVADMKMQLELARSMSYYASLKLGAPAEERRRALSRAKVQLGQSMRFVGQQS
VQLHGGIGVTDEYIGSHYFKKLTQLEMTWGDTLHHLGEVSARMQDTAGVFA

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=302, Percent_Identity=25.1655629139073, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4557233, Length=322, Percent_Identity=24.8447204968944, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI226958414, Length=262, Percent_Identity=25.9541984732824, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI4557235, Length=316, Percent_Identity=27.8481012658228, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI76496475, Length=316, Percent_Identity=27.8481012658228, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI4501859, Length=319, Percent_Identity=25.3918495297806, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI7656849, Length=228, Percent_Identity=28.0701754385965, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI21361497, Length=361, Percent_Identity=24.3767313019391, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17538396, Length=352, Percent_Identity=25.8522727272727, Blast_Score=108, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI17506239, Length=350, Percent_Identity=26.5714285714286, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17508101, Length=317, Percent_Identity=27.4447949526814, Blast_Score=91, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71985184, Length=326, Percent_Identity=26.3803680981595, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI71990804, Length=263, Percent_Identity=26.2357414448669, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI71985192, Length=303, Percent_Identity=26.4026402640264, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17569725, Length=367, Percent_Identity=23.7057220708447, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17534899, Length=364, Percent_Identity=22.5274725274725, Blast_Score=68, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17570075, Length=363, Percent_Identity=25.3443526170799, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=26.8398268398268, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356377, Length=359, Percent_Identity=25.3481894150418, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24646207, Length=324, Percent_Identity=25.3086419753086, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21355753, Length=303, Percent_Identity=26.0726072607261, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24666513, Length=348, Percent_Identity=23.5632183908046, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281363737, Length=308, Percent_Identity=23.7012987012987, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 39817; Mature: 39817

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDFDFSEDQQSLRDAVRRWVDKGYTFERRRGIVAAGGFDRAAYGELAELGLTALTVPEAH
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHCCEEEECCCCHHHHHHHHHCCCEEEECCCCC
DGLGQGAVDAMVAMEELGRGIVLEPLAQTFVASGMLAQCAPEAVQAAWLPRIASGEALVV
CCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHCCHHHHHCHHHHHHHHCCCCCCCCEEEE
LAHQERKARYRLDVCEAQATGSGDSATVTGTKSLVPAGDQADAFLVPAQHQGRVALFLVE
EECCCCCHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCEEEECCCCCCCEEEEEEE
RGAQGVATRGYVTQDGSRAAEVQFDNAPATLVAEDGLAALELAVDIGIAAACAEAVGVMD
CCCCCCEECCEEECCCCCEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
QTVALTVDYMNQRKQFGVPIATFQALRHRVADMKMQLELARSMSYYASLKLGAPAEERRR
HHHEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHH
ALSRAKVQLGQSMRFVGQQSVQLHGGIGVTDEYIGSHYFKKLTQLEMTWGDTLHHLGEVS
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARMQDTAGVFA
HHHHHHCCCCC
>Mature Secondary Structure
MDFDFSEDQQSLRDAVRRWVDKGYTFERRRGIVAAGGFDRAAYGELAELGLTALTVPEAH
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHCCEEEECCCCHHHHHHHHHCCCEEEECCCCC
DGLGQGAVDAMVAMEELGRGIVLEPLAQTFVASGMLAQCAPEAVQAAWLPRIASGEALVV
CCCCCHHHHHHHHHHHHCCCEEEHHHHHHHHHCCHHHHHCHHHHHHHHCCCCCCCCEEEE
LAHQERKARYRLDVCEAQATGSGDSATVTGTKSLVPAGDQADAFLVPAQHQGRVALFLVE
EECCCCCHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCCCCCEEEECCCCCCCEEEEEEE
RGAQGVATRGYVTQDGSRAAEVQFDNAPATLVAEDGLAALELAVDIGIAAACAEAVGVMD
CCCCCCEECCEEECCCCCEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
QTVALTVDYMNQRKQFGVPIATFQALRHRVADMKMQLELARSMSYYASLKLGAPAEERRR
HHHEEEEHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHH
ALSRAKVQLGQSMRFVGQQSVQLHGGIGVTDEYIGSHYFKKLTQLEMTWGDTLHHLGEVS
HHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARMQDTAGVFA
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]