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The map label for this gene is trxB [H]

Identifier: 120612080

GI number: 120612080

Start: 3786267

End: 3787226

Strand: Direct

Name: trxB [H]

Synonym: Aave_3427

Alternate gene names: 120612080

Gene position: 3786267-3787226 (Clockwise)

Preceding gene: 120612077

Following gene: 120612081

Centisome position: 70.73

GC content: 66.98

Gene sequence:

>960_bases
ATGTCCACTACGCAACACGCCAAAGTCATGATCCTGGGCTCCGGCCCCGCCGGCTACACGGCCGCCGTGTACGCCGCCCG
CGCCAACCTGAATCCCGTGCTGATCACCGGCATCGCGCAGGGCGGCCAACTCATGACGACGACGGAAGTGGACAACTGGC
CCGCCGACGTGAACGGTGTGCAGGGCCCGGAACTGATGCAGCGCTTCCTGGAGCACGCCGAGCGCTTCAAGACCCAGGTG
GTGTTCGACCACATCAACCAGGTGGACCTGTCCAAGCGCCCGTTCACGCTCACCGGCGACAGCGGCACCTACACCTGCGA
CGCGCTCATCATCGCCACGGGCGCCTCGGCCAAGTACCTGGGGCTGCCCTCCGAAGAGGCGTTCATGGGCCGCGGCGTCT
CGGGCTGCGCGACCTGCGACGGCTTCTTCTACCGCGAGCAGGACGTGTGCGTGGTGGGCGGCGGCAACACCGCCGTGGAA
GAAGCGCTCTACCTCTCCAACATCGCCCGCAAGGTGACGCTGGTGCACCGGCGCGACAAGTTCAAGGCCGAGCCCATCCT
GGTGGACAAGCTCAACGAGAAGGTCGCCGCCGGCAAGATCGAGCTGAAGGTGTTCCACACGCTCGACGAGGTGCTGGGCA
ACGACAGTGGCGTGACGGGCATCCGCATCAGGAGCACGCAGGACGGCAGCACCCAGGACATCGCCCTGCAGGGCTGCTTC
ATCGCCATCGGCCATGCGCCCAACACCGGCATCTTCGAAGGCCAGCTGACGCTGGAGAACGGCTACATCGTCACGCAGGG
CGGCCTCAAGGGCTTCGCCACGCAGACCAGCGTGCCCGGCGTGTTCGCGGCCGGCGACGTGCAGGACCACGTCTATCGCC
AGGCGATCACCAGCGCCGGCACGGGCTGCATGGCGGCGCTCGACGCACAGCGTTTCCTGGAGCAGGAAGGCGTGATCTGA

Upstream 100 bases:

>100_bases
CCCGCGCCCGCGCGGGCCGGCCCCGGGTGGATACTCGTGGAACCGACCGCATGGACGGAATGCACCCGCCACCCGGCGGC
ACAAACTCTTACCTTTCACC

Downstream 100 bases:

>100_bases
CGCCCTGCCCGGTCCGTCCGCGCGGGCGGCAGCCGTGCGGGCTGGACACCCATTTGAAGGCCGCGCTATAATGCGCGGCT
TTGCTGCATCTTGCGCACCG

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MSTTQHAKVMILGSGPAGYTAAVYAARANLNPVLITGIAQGGQLMTTTEVDNWPADVNGVQGPELMQRFLEHAERFKTQV
VFDHINQVDLSKRPFTLTGDSGTYTCDALIIATGASAKYLGLPSEEAFMGRGVSGCATCDGFFYREQDVCVVGGGNTAVE
EALYLSNIARKVTLVHRRDKFKAEPILVDKLNEKVAAGKIELKVFHTLDEVLGNDSGVTGIRIRSTQDGSTQDIALQGCF
IAIGHAPNTGIFEGQLTLENGYIVTQGGLKGFATQTSVPGVFAAGDVQDHVYRQAITSAGTGCMAALDAQRFLEQEGVI

Sequences:

>Translated_319_residues
MSTTQHAKVMILGSGPAGYTAAVYAARANLNPVLITGIAQGGQLMTTTEVDNWPADVNGVQGPELMQRFLEHAERFKTQV
VFDHINQVDLSKRPFTLTGDSGTYTCDALIIATGASAKYLGLPSEEAFMGRGVSGCATCDGFFYREQDVCVVGGGNTAVE
EALYLSNIARKVTLVHRRDKFKAEPILVDKLNEKVAAGKIELKVFHTLDEVLGNDSGVTGIRIRSTQDGSTQDIALQGCF
IAIGHAPNTGIFEGQLTLENGYIVTQGGLKGFATQTSVPGVFAAGDVQDHVYRQAITSAGTGCMAALDAQRFLEQEGVI
>Mature_318_residues
STTQHAKVMILGSGPAGYTAAVYAARANLNPVLITGIAQGGQLMTTTEVDNWPADVNGVQGPELMQRFLEHAERFKTQVV
FDHINQVDLSKRPFTLTGDSGTYTCDALIIATGASAKYLGLPSEEAFMGRGVSGCATCDGFFYREQDVCVVGGGNTAVEE
ALYLSNIARKVTLVHRRDKFKAEPILVDKLNEKVAAGKIELKVFHTLDEVLGNDSGVTGIRIRSTQDGSTQDIALQGCFI
AIGHAPNTGIFEGQLTLENGYIVTQGGLKGFATQTSVPGVFAAGDVQDHVYRQAITSAGTGCMAALDAQRFLEQEGVI

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=315, Percent_Identity=69.5238095238095, Blast_Score=464, Evalue=1e-132,
Organism=Escherichia coli, GI87081763, Length=319, Percent_Identity=31.0344827586207, Blast_Score=125, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6320560, Length=320, Percent_Identity=45, Blast_Score=265, Evalue=1e-71,
Organism=Saccharomyces cerevisiae, GI6321898, Length=329, Percent_Identity=42.8571428571429, Blast_Score=258, Evalue=1e-69,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33953; Mature: 33822

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTTQHAKVMILGSGPAGYTAAVYAARANLNPVLITGIAQGGQLMTTTEVDNWPADVNGV
CCCCCCEEEEEEECCCCCCEEEEEEEECCCCEEEEEEECCCCEEEEEEECCCCCCCCCCC
QGPELMQRFLEHAERFKTQVVFDHINQVDLSKRPFTLTGDSGTYTCDALIIATGASAKYL
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEEEEEECCCCEEE
GLPSEEAFMGRGVSGCATCDGFFYREQDVCVVGGGNTAVEEALYLSNIARKVTLVHRRDK
CCCCCHHHHCCCCCCCEECCCEEEECCCEEEECCCCHHHHHHHHHHHHHHHHHEEECCCC
FKAEPILVDKLNEKVAAGKIELKVFHTLDEVLGNDSGVTGIRIRSTQDGSTQDIALQGCF
CCCCCEEEECCCCHHHCCEEEEEEHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEEEEE
IAIGHAPNTGIFEGQLTLENGYIVTQGGLKGFATQTSVPGVFAAGDVQDHVYRQAITSAG
EEEECCCCCCEEEEEEEEECCEEEECCCCCCCEECCCCCCEEEECCHHHHHHHHHHHHCC
TGCMAALDAQRFLEQEGVI
CCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
STTQHAKVMILGSGPAGYTAAVYAARANLNPVLITGIAQGGQLMTTTEVDNWPADVNGV
CCCCCEEEEEEECCCCCCEEEEEEEECCCCEEEEEEECCCCEEEEEEECCCCCCCCCCC
QGPELMQRFLEHAERFKTQVVFDHINQVDLSKRPFTLTGDSGTYTCDALIIATGASAKYL
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCEEEEEEEEEECCCCEEE
GLPSEEAFMGRGVSGCATCDGFFYREQDVCVVGGGNTAVEEALYLSNIARKVTLVHRRDK
CCCCCHHHHCCCCCCCEECCCEEEECCCEEEECCCCHHHHHHHHHHHHHHHHHEEECCCC
FKAEPILVDKLNEKVAAGKIELKVFHTLDEVLGNDSGVTGIRIRSTQDGSTQDIALQGCF
CCCCCEEEECCCCHHHCCEEEEEEHHHHHHHHCCCCCCEEEEEECCCCCCCCEEEEEEEE
IAIGHAPNTGIFEGQLTLENGYIVTQGGLKGFATQTSVPGVFAAGDVQDHVYRQAITSAG
EEEECCCCCCEEEEEEEEECCEEEECCCCCCCEECCCCCCEEEECCHHHHHHHHHHHHCC
TGCMAALDAQRFLEQEGVI
CCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]