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The map label for this gene is mhpD [H]

Identifier: 120612070

GI number: 120612070

Start: 3773155

End: 3774024

Strand: Reverse

Name: mhpD [H]

Synonym: Aave_3417

Alternate gene names: 120612070

Gene position: 3774024-3773155 (Counterclockwise)

Preceding gene: 120612072

Following gene: 120612069

Centisome position: 70.51

GC content: 71.95

Gene sequence:

>870_bases
ATGGCCCTGCAGCAAACCCTCATCGCGGCGCTGGCCGCCGTCGCCTGCGTTACAGGAGCGCGGGCCGCGTGCCTGGACGA
TGCGCAGGTGGCCGATCTCGCGGCGCACTACATGGCCCGCACGCCCGCGGCCAATCCGCCGCCCATGGACGCCGCCGATG
CCGCCTGCACCCGCGGCAAGTTCAATGCGCTGCTGGAGCAGCGCCTGGGCCGGCCCGTCGGCTACAAGGCCGGCCTCACC
AACCCGGCGGTACAGCAGCGCTTCCGTACGGACCAGCCCGTGTGGGGCCGCCTCTATCCGGGCATGGTGCTACCCTCCGG
CAGCACCGTGGATGCTGCCTTCGGTGCACGGCCGCTCTATGAAGCCGACATGCTGGTTCGCGTGAAGAGCACAGCCGTCA
ACCACGCGCGCACGCCGCTGGAGGTACTGGACGCCATCGACCAGGTGATTCCCTTCATCGAACTGCCCGACCTGCTGGTG
CAGGTGCCGCCCCAGCTCGACGGGGCGGGCGTGGCTGCGATCAACGTGGGTGCGCGCCTGGGCGTGGCCGGCACGCCTAT
CGCCGTGCCGGCGCTGCGGGCCGAGCGCTACGCGATGCTCGATGCCCTGGCCGCGATGACGGTCACGCTCACCGACGGCA
CGGGCGCCAGGCTCGGCGGCGGCCGCGGCAGCGACATCCTGGGGCATCCGCTGCAGGCCGTGGTGTGGCTGGCCGGTGCG
CTGCAGAAGGAAGACGCCGCGCTGAAGCCGGGCGACCTTGTCAGCCTGGGCTCGTTCTCCGCATTGCTGCCGCCGCGGCC
GGGCCTTGCGGTGACGGCCACGTTCGCCGGACTGCCGGGGGCCGCGCCCGTGGAAGTGCGTTTCAGGTAA

Upstream 100 bases:

>100_bases
TGTAGTGGATGAGGGCCATGGTGGTGATGGGGGTTGCCAGGATGCGCGCCCTGGCGTATTGGTGGTCTGATCACGCCAAT
CTACAACCCCGGAGCTTTCC

Downstream 100 bases:

>100_bases
GAAGCTATGGCCGCGGCTGCGTCCTGCGCCCCGGTCGCGCAGGGCACTGCAGGCGGCACCGGTTTCGGGGATGATCGGCG
ATGCGCCGCAGTGCGTGTTC

Product: hydratase/decarboxylase

Products: NA

Alternate protein names: 2-hydroxypentadienoic acid hydratase [H]

Number of amino acids: Translated: 289; Mature: 288

Protein sequence:

>289_residues
MALQQTLIAALAAVACVTGARAACLDDAQVADLAAHYMARTPAANPPPMDAADAACTRGKFNALLEQRLGRPVGYKAGLT
NPAVQQRFRTDQPVWGRLYPGMVLPSGSTVDAAFGARPLYEADMLVRVKSTAVNHARTPLEVLDAIDQVIPFIELPDLLV
QVPPQLDGAGVAAINVGARLGVAGTPIAVPALRAERYAMLDALAAMTVTLTDGTGARLGGGRGSDILGHPLQAVVWLAGA
LQKEDAALKPGDLVSLGSFSALLPPRPGLAVTATFAGLPGAAPVEVRFR

Sequences:

>Translated_289_residues
MALQQTLIAALAAVACVTGARAACLDDAQVADLAAHYMARTPAANPPPMDAADAACTRGKFNALLEQRLGRPVGYKAGLT
NPAVQQRFRTDQPVWGRLYPGMVLPSGSTVDAAFGARPLYEADMLVRVKSTAVNHARTPLEVLDAIDQVIPFIELPDLLV
QVPPQLDGAGVAAINVGARLGVAGTPIAVPALRAERYAMLDALAAMTVTLTDGTGARLGGGRGSDILGHPLQAVVWLAGA
LQKEDAALKPGDLVSLGSFSALLPPRPGLAVTATFAGLPGAAPVEVRFR
>Mature_288_residues
ALQQTLIAALAAVACVTGARAACLDDAQVADLAAHYMARTPAANPPPMDAADAACTRGKFNALLEQRLGRPVGYKAGLTN
PAVQQRFRTDQPVWGRLYPGMVLPSGSTVDAAFGARPLYEADMLVRVKSTAVNHARTPLEVLDAIDQVIPFIELPDLLVQ
VPPQLDGAGVAAINVGARLGVAGTPIAVPALRAERYAMLDALAAMTVTLTDGTGARLGGGRGSDILGHPLQAVVWLAGAL
QKEDAALKPGDLVSLGSFSALLPPRPGLAVTATFAGLPGAAPVEVRFR

Specific function: Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid [H]

COG id: COG3971

COG function: function code Q; 2-keto-4-pentenoate hydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hydratase/decarboxylase family. MhpD subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081722, Length=236, Percent_Identity=28.8135593220339, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: =4.2.1.80 [H]

Molecular weight: Translated: 29833; Mature: 29702

Theoretical pI: Translated: 7.44; Mature: 7.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALQQTLIAALAAVACVTGARAACLDDAQVADLAAHYMARTPAANPPPMDAADAACTRGK
CCHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
FNALLEQRLGRPVGYKAGLTNPAVQQRFRTDQPVWGRLYPGMVLPSGSTVDAAFGARPLY
HHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCHHCCCCEECCCCCCCCHHHCCCCCC
EADMLVRVKSTAVNHARTPLEVLDAIDQVIPFIELPDLLVQVPPQLDGAGVAAINVGARL
CCHHEEEEHHHHHHHCCCHHHHHHHHHHHHCHHCCCHHHHCCCCCCCCCCEEEEECCCCC
GVAGTPIAVPALRAERYAMLDALAAMTVTLTDGTGARLGGGRGSDILGHPLQAVVWLAGA
CCCCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHH
LQKEDAALKPGDLVSLGSFSALLPPRPGLAVTATFAGLPGAAPVEVRFR
HHCCCCCCCCCCEEECCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEC
>Mature Secondary Structure 
ALQQTLIAALAAVACVTGARAACLDDAQVADLAAHYMARTPAANPPPMDAADAACTRGK
CHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
FNALLEQRLGRPVGYKAGLTNPAVQQRFRTDQPVWGRLYPGMVLPSGSTVDAAFGARPLY
HHHHHHHHCCCCCCCCCCCCCHHHHHHHCCCCCCCHHCCCCEECCCCCCCCHHHCCCCCC
EADMLVRVKSTAVNHARTPLEVLDAIDQVIPFIELPDLLVQVPPQLDGAGVAAINVGARL
CCHHEEEEHHHHHHHCCCHHHHHHHHHHHHCHHCCCHHHHCCCCCCCCCCEEEEECCCCC
GVAGTPIAVPALRAERYAMLDALAAMTVTLTDGTGARLGGGRGSDILGHPLQAVVWLAGA
CCCCCCCCHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHH
LQKEDAALKPGDLVSLGSFSALLPPRPGLAVTATFAGLPGAAPVEVRFR
HHCCCCCCCCCCEEECCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA