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The map label for this gene is foxA [H]

Identifier: 120611982

GI number: 120611982

Start: 3677583

End: 3679796

Strand: Reverse

Name: foxA [H]

Synonym: Aave_3326

Alternate gene names: 120611982

Gene position: 3679796-3677583 (Counterclockwise)

Preceding gene: 120611986

Following gene: 120611981

Centisome position: 68.75

GC content: 71.86

Gene sequence:

>2214_bases
ATGCCTTTCTCTTCCGTCTCCGGGCCCCGCGCGTGGGCTGTCCTGCTGGGTGCCGTGCCCGTGGCTGCCATGGCGCAGTC
GCCCGCTTCCGATTCGTCGCCCACCCAACTGCCGCCGGTGGAGGTGCGCGAGCGCGCCGAAACGCCGCGCCTCGCGCAGC
CTGCCGCCGCGGCCTCGCGCCTGGGGCTGACCGTGCGCGAGACGCCGGCCTCCATCGACGTGGTGCCGCGCGAGATGCTG
GCCGAGCGCGGGTCGCGCACGGTGTCGGAGGCCGCGCAGGCGGCCGTGGGCGTGCTGGCGGGGGATTTTCCTGCGGAGCC
GGCTGCGTTCTCCATGCGCGGCTTCGCCAACAGCCAGATCAACACCCTCTACAACGGCATCAAGATAGGCCCGCCGAACA
TGACCTCGCGCGTCATGGGCACGGCGAATCTCGAACGCGTGGAGTTCCTCAAGGGACCCGCGTCGCTGATGTCGGGCGAG
GGCGCGGCCGGCGGCGCGGTGAACTTCGTCACGCGCGCGCCGCACCGCGGCCCGGTGGAAACCGAGGTGACCGCCGCGGC
CGGATCCTTCGGCGAGCGGCGCCTGTCCGTCGGCACCGGCGGCACCACGGCCCGGAAGGACGTGGACTTCCGCCTCGACG
CGAGCGGTTCGGACAATGACGGCTTCGTGCGGGACACGGGCCAGCGCCTGTGGCACCTGTCGGGCGGCCTGGACTGGTAC
CTGCGGCCGGGGCTCAAGCTGTTCGTCGCCGCTGAAGTGCAGCGCGACCGCGGCCATCCGTACTGGGGCACGCCGCTGGT
CTCCGCGGCGGCGCCGGGCATCCAGGCGCAGCCGGGCGTGGTGTCCGGCACCTATGTGTCGGGCTTCAACGGCAGCGTGC
TCGCACCGGTGGCCATCGACCGCCGCACGCTGCGCACGAACTACAACGTGCTGGACAACCGCAACGAAGCGCGCGAGACC
TGGCTGCGCACGGGCGTGGACTGGCGCATCGACGCCGCGTGGACGCTGCGCAGCCAGCTCTACCGCTACACCGCCACGCG
CTCGTGGCTGAACAACGAGGTGCTCGCGTTCAACACCGGCACCGGCCTGGTGGACCGCGAGCGTTTCTTCGTGGCGCAGG
ACCAGACGACCACAGGCAACAAGACCGAACTGCAGTGGGACGGTCGTCTGGCAGGCCGGGAAAACCGCTTCGTCGCCGCG
CTGGAACTGAGCGACACGGACCTGGACCGCCCCGGCGCCGCCAACTTCCCCGGCGACAGCGTGTCGCTGATTTCACCCGA
CCGCGGCTTCTACGGCCCGCTGGTGCAGCAGCGGCAGACCACGCGGTTGCGCAATGCGGCGGTCGCGCTGGAGGACCGGC
TGCGCATCACGCCCGCCGTGGCCCTCATTGGAGGCCTGCGGCACGAATCCATCGAACTCGACCGCACCTCCACCGACGCG
GCGGGCGCGGCGCGCCGCGGCTTTCCCTACGGCAAGACCTGGCACCCGACCACCGGCCGGCTGGGCCTGACGTGGGAGCC
CGCGGCGGGCACCATGCTCTACGCCCAGGCCGCGACGGGTGCCGACGTGGCCGCCAACAACATCTTCCTGCTCGGCCCCG
GCCAGCCGCTGGAGCTCACCCGGGCGCGCAATGCCGAGGTGGGCGTCAAGCAGGGCTTCTGGCAGGACCGCGGCGAATGG
ACGCTGGCCCTCTACGATGCCGAGCGCCGCAACGTCTATGCGGGGCAGGGTGGCCAGTCGCTGGCGCGCGCCGGCGCGCT
GCGATCGCGTGGCGCGGAGCTGTCCCTGGCGCTGCGCCCCGCGGCCGCCTGGAGCGTCTGGACGCAACTGGCCTTCAACC
GTGCGCGCTACGATGATTTCGTGCTGGCCAACGGTACATCCTTCTCCGGCCACACCCCGCCCAACACCCCGAAGGTGATG
GCCAGCGTCGGCGCGGCCTACCGCTTCACCGCGGGCCTGCCGATGCAGATCTCCGCTTCGCTGCGGCACGTGGGCGAGCG
CTTCCACAGCGACGCCAACACGGTCCGCCTGTCGGCCTACCGCGTGATCGATGCGGCCTGGAGCGTGGACGTGGCCCCGG
GCACCCAGCTCACCCTGCGGGGCCGCAACCTGGCCAACAAGGTCTATGCCGCCTGGGCGGATCCGTTCTACCCGGACCAG
ATCCTGCTCGGCGCGCCGCGCAGTTTCGAGCTGGCCCTGCGCTGGACGCTCTGA

Upstream 100 bases:

>100_bases
TCTGCATGGGTGCCATGATTTTTGTTAATGCAACACGATTGCGTTAACATCGGCAACAGCGGCACCGTCGAGCGTGCCCG
CGTGTCGCCGACAATATTCC

Downstream 100 bases:

>100_bases
CGCGGGCTGTGGACATGGTCGTGGCATTGCAGGCCGAAGGCCTCGGATGGAAGTCGCCACGCGGCGACTGGCTGCTGCAG
GACGTGGGGCTGGAAGCCGG

Product: TonB-dependent receptor, plug

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 737; Mature: 736

Protein sequence:

>737_residues
MPFSSVSGPRAWAVLLGAVPVAAMAQSPASDSSPTQLPPVEVRERAETPRLAQPAAAASRLGLTVRETPASIDVVPREML
AERGSRTVSEAAQAAVGVLAGDFPAEPAAFSMRGFANSQINTLYNGIKIGPPNMTSRVMGTANLERVEFLKGPASLMSGE
GAAGGAVNFVTRAPHRGPVETEVTAAAGSFGERRLSVGTGGTTARKDVDFRLDASGSDNDGFVRDTGQRLWHLSGGLDWY
LRPGLKLFVAAEVQRDRGHPYWGTPLVSAAAPGIQAQPGVVSGTYVSGFNGSVLAPVAIDRRTLRTNYNVLDNRNEARET
WLRTGVDWRIDAAWTLRSQLYRYTATRSWLNNEVLAFNTGTGLVDRERFFVAQDQTTTGNKTELQWDGRLAGRENRFVAA
LELSDTDLDRPGAANFPGDSVSLISPDRGFYGPLVQQRQTTRLRNAAVALEDRLRITPAVALIGGLRHESIELDRTSTDA
AGAARRGFPYGKTWHPTTGRLGLTWEPAAGTMLYAQAATGADVAANNIFLLGPGQPLELTRARNAEVGVKQGFWQDRGEW
TLALYDAERRNVYAGQGGQSLARAGALRSRGAELSLALRPAAAWSVWTQLAFNRARYDDFVLANGTSFSGHTPPNTPKVM
ASVGAAYRFTAGLPMQISASLRHVGERFHSDANTVRLSAYRVIDAAWSVDVAPGTQLTLRGRNLANKVYAAWADPFYPDQ
ILLGAPRSFELALRWTL

Sequences:

>Translated_737_residues
MPFSSVSGPRAWAVLLGAVPVAAMAQSPASDSSPTQLPPVEVRERAETPRLAQPAAAASRLGLTVRETPASIDVVPREML
AERGSRTVSEAAQAAVGVLAGDFPAEPAAFSMRGFANSQINTLYNGIKIGPPNMTSRVMGTANLERVEFLKGPASLMSGE
GAAGGAVNFVTRAPHRGPVETEVTAAAGSFGERRLSVGTGGTTARKDVDFRLDASGSDNDGFVRDTGQRLWHLSGGLDWY
LRPGLKLFVAAEVQRDRGHPYWGTPLVSAAAPGIQAQPGVVSGTYVSGFNGSVLAPVAIDRRTLRTNYNVLDNRNEARET
WLRTGVDWRIDAAWTLRSQLYRYTATRSWLNNEVLAFNTGTGLVDRERFFVAQDQTTTGNKTELQWDGRLAGRENRFVAA
LELSDTDLDRPGAANFPGDSVSLISPDRGFYGPLVQQRQTTRLRNAAVALEDRLRITPAVALIGGLRHESIELDRTSTDA
AGAARRGFPYGKTWHPTTGRLGLTWEPAAGTMLYAQAATGADVAANNIFLLGPGQPLELTRARNAEVGVKQGFWQDRGEW
TLALYDAERRNVYAGQGGQSLARAGALRSRGAELSLALRPAAAWSVWTQLAFNRARYDDFVLANGTSFSGHTPPNTPKVM
ASVGAAYRFTAGLPMQISASLRHVGERFHSDANTVRLSAYRVIDAAWSVDVAPGTQLTLRGRNLANKVYAAWADPFYPDQ
ILLGAPRSFELALRWTL
>Mature_736_residues
PFSSVSGPRAWAVLLGAVPVAAMAQSPASDSSPTQLPPVEVRERAETPRLAQPAAAASRLGLTVRETPASIDVVPREMLA
ERGSRTVSEAAQAAVGVLAGDFPAEPAAFSMRGFANSQINTLYNGIKIGPPNMTSRVMGTANLERVEFLKGPASLMSGEG
AAGGAVNFVTRAPHRGPVETEVTAAAGSFGERRLSVGTGGTTARKDVDFRLDASGSDNDGFVRDTGQRLWHLSGGLDWYL
RPGLKLFVAAEVQRDRGHPYWGTPLVSAAAPGIQAQPGVVSGTYVSGFNGSVLAPVAIDRRTLRTNYNVLDNRNEARETW
LRTGVDWRIDAAWTLRSQLYRYTATRSWLNNEVLAFNTGTGLVDRERFFVAQDQTTTGNKTELQWDGRLAGRENRFVAAL
ELSDTDLDRPGAANFPGDSVSLISPDRGFYGPLVQQRQTTRLRNAAVALEDRLRITPAVALIGGLRHESIELDRTSTDAA
GAARRGFPYGKTWHPTTGRLGLTWEPAAGTMLYAQAATGADVAANNIFLLGPGQPLELTRARNAEVGVKQGFWQDRGEWT
LALYDAERRNVYAGQGGQSLARAGALRSRGAELSLALRPAAAWSVWTQLAFNRARYDDFVLANGTSFSGHTPPNTPKVMA
SVGAAYRFTAGLPMQISASLRHVGERFHSDANTVRLSAYRVIDAAWSVDVAPGTQLTLRGRNLANKVYAAWADPFYPDQI
LLGAPRSFELALRWTL

Specific function: Ferrioxamine binding and uptake, in association with the tonB protein. May play a role in intestinal colonization [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1787344, Length=272, Percent_Identity=24.2647058823529, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 79443; Mature: 79312

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFSSVSGPRAWAVLLGAVPVAAMAQSPASDSSPTQLPPVEVRERAETPRLAQPAAAASR
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHH
LGLTVRETPASIDVVPREMLAERGSRTVSEAAQAAVGVLAGDFPAEPAAFSMRGFANSQI
CCCEEECCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCHH
NTLYNGIKIGPPNMTSRVMGTANLERVEFLKGPASLMSGEGAAGGAVNFVTRAPHRGPVE
HHHHCCEEECCCCHHHHHHCCCCCHHHHHHCCCHHHHCCCCCCCCCEEEEECCCCCCCCC
TEVTAAAGSFGERRLSVGTGGTTARKDVDFRLDASGSDNDGFVRDTGQRLWHLSGGLDWY
CEEEECCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCCEECCCCEEEEECCCCCEE
LRPGLKLFVAAEVQRDRGHPYWGTPLVSAAAPGIQAQPGVVSGTYVSGFNGSVLAPVAID
ECCCEEEEEEEEEHHCCCCCCCCCCHHHHCCCCCCCCCCEEECEEECCCCCCEEEEEEEC
RRTLRTNYNVLDNRNEARETWLRTGVDWRIDAAWTLRSQLYRYTATRSWLNNEVLAFNTG
CEEHCCCCCCCCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECC
TGLVDRERFFVAQDQTTTGNKTELQWDGRLAGRENRFVAALELSDTDLDRPGAANFPGDS
CCCEECCEEEEEECCCCCCCCEEEEECCEECCCCCCEEEEEEECCCCCCCCCCCCCCCCC
VSLISPDRGFYGPLVQQRQTTRLRNAAVALEDRLRITPAVALIGGLRHESIELDRTSTDA
EEEECCCCCCCCHHHHHHHHHHHHHHHHEECCCCEECHHHHHHHCCCCCCEEECCCCCCC
AGAARRGFPYGKTWHPTTGRLGLTWEPAAGTMLYAQAATGADVAANNIFLLGPGQPLELT
CCHHHCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCEECCCEEEECCCCCEEEE
RARNAEVGVKQGFWQDRGEWTLALYDAERRNVYAGQGGQSLARAGALRSRGAELSLALRP
CCCCCCCCHHCCCCCCCCCEEEEEEECCCCEEECCCCCHHHHHHHHHHHCCCEEEEEECC
AAAWSVWTQLAFNRARYDDFVLANGTSFSGHTPPNTPKVMASVGAAYRFTAGLPMQISAS
HHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHCCCEEEECCCCHHHHHH
LRHVGERFHSDANTVRLSAYRVIDAAWSVDVAPGTQLTLRGRNLANKVYAAWADPFYPDQ
HHHHHHHHCCCCCEEEEEEEEEEEEHEEEECCCCCEEEEECCCCCCHHEEEECCCCCCCC
ILLGAPRSFELALRWTL
EEECCCCCEEEEEEEEC
>Mature Secondary Structure 
PFSSVSGPRAWAVLLGAVPVAAMAQSPASDSSPTQLPPVEVRERAETPRLAQPAAAASR
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCCCCHHHHHH
LGLTVRETPASIDVVPREMLAERGSRTVSEAAQAAVGVLAGDFPAEPAAFSMRGFANSQI
CCCEEECCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCHH
NTLYNGIKIGPPNMTSRVMGTANLERVEFLKGPASLMSGEGAAGGAVNFVTRAPHRGPVE
HHHHCCEEECCCCHHHHHHCCCCCHHHHHHCCCHHHHCCCCCCCCCEEEEECCCCCCCCC
TEVTAAAGSFGERRLSVGTGGTTARKDVDFRLDASGSDNDGFVRDTGQRLWHLSGGLDWY
CEEEECCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCCCCCEECCCCEEEEECCCCCEE
LRPGLKLFVAAEVQRDRGHPYWGTPLVSAAAPGIQAQPGVVSGTYVSGFNGSVLAPVAID
ECCCEEEEEEEEEHHCCCCCCCCCCHHHHCCCCCCCCCCEEECEEECCCCCCEEEEEEEC
RRTLRTNYNVLDNRNEARETWLRTGVDWRIDAAWTLRSQLYRYTATRSWLNNEVLAFNTG
CEEHCCCCCCCCCCCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCEEEEECC
TGLVDRERFFVAQDQTTTGNKTELQWDGRLAGRENRFVAALELSDTDLDRPGAANFPGDS
CCCEECCEEEEEECCCCCCCCEEEEECCEECCCCCCEEEEEEECCCCCCCCCCCCCCCCC
VSLISPDRGFYGPLVQQRQTTRLRNAAVALEDRLRITPAVALIGGLRHESIELDRTSTDA
EEEECCCCCCCCHHHHHHHHHHHHHHHHEECCCCEECHHHHHHHCCCCCCEEECCCCCCC
AGAARRGFPYGKTWHPTTGRLGLTWEPAAGTMLYAQAATGADVAANNIFLLGPGQPLELT
CCHHHCCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCCCEECCCEEEECCCCCEEEE
RARNAEVGVKQGFWQDRGEWTLALYDAERRNVYAGQGGQSLARAGALRSRGAELSLALRP
CCCCCCCCHHCCCCCCCCCEEEEEEECCCCEEECCCCCHHHHHHHHHHHCCCEEEEEECC
AAAWSVWTQLAFNRARYDDFVLANGTSFSGHTPPNTPKVMASVGAAYRFTAGLPMQISAS
HHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHCCCEEEECCCCHHHHHH
LRHVGERFHSDANTVRLSAYRVIDAAWSVDVAPGTQLTLRGRNLANKVYAAWADPFYPDQ
HHHHHHHHCCCCCEEEEEEEEEEEEHEEEECCCCCEEEEECCCCCCHHEEEECCCCCCCC
ILLGAPRSFELALRWTL
EEECCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 10103258; 7642488 [H]