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The map label for this gene is adiA [H]

Identifier: 120611915

GI number: 120611915

Start: 3600450

End: 3602831

Strand: Reverse

Name: adiA [H]

Synonym: Aave_3257

Alternate gene names: 120611915

Gene position: 3602831-3600450 (Counterclockwise)

Preceding gene: 120611920

Following gene: 120611914

Centisome position: 67.31

GC content: 64.86

Gene sequence:

>2382_bases
ATGAAATTCCGCTTTCCCATCGTCATCATCGACGAGGACTACCGTTCCGAGAATACATCGGGCCTGGGTATCCGGGCCCT
GGCCCAGGCGATCGAGGCCGAGGGTTTCGAGGTGCTCGGCGTGACGAGCTACGGCGACCTGTCGCAGTTCGCGCAGCAGC
AGAGCCGGGCGAGCGCCTTCATCCTGTCGATCGACGACGAGGAGTTCACGCTGGGCTCGGGGCTGGACCCGATCGTGCTG
AGCCTGCGCAACTTCATCGCCCAGGTGCGCCGCAAGAATTCCGACGTGCCGATCTACGTGCACGGCGAGACCAAGACCGC
GCGCCACCTGCCCAACGACATCCTGCGCGAGCTGCACGGCTTCATCCACATGTTCGAGGACACGCCGGAGTTCGTGGCCA
AGCACATCATCCGCGAGGCCAAGAGCTACCTGGAGAGCGTGCAGCCGCCGTTCTTCAAGGCGCTGCTGGACTATGCGGAA
GACGGCTCCTACTCGTGGCACTGCCCGGGCCACTCCGGCGGCGTGGCGTTCCTCAAGAGCCCCGTGGGCCAGATGTTCCA
CCAGTTCTTCGGCGAGAACATGCTGCGCGCGGACGTGTGCAACGCCGTGGAGGAGCTGGGCCAGCTGCTGGACCACAACG
GGGCCATCGGCGAGAGCGAGCGCAACGCGGCGCGCATCTTCAATGCCGACCACTGCTTCTTCGTGACCAACGGCACGAGC
ACCTCGAACAAGATGGTGTGGCACCACACGGTGGCGCCGGGCGACGTGGTGGTGGTGGACCGCAATTGCCACAAGTCCAT
CCTGCACTCGATCATCATGACCGGGGCGATCCCCGTGTTCCTGAAGCCCACGCGCAACCACTTCGGCATCATCGGCCCGA
TCCCGCAGGCCGAGTTCGAGAAGGAGGCGATCCAGGCGAAGATCCGCGCCAACCCGCTGCTCAAGGGCGTGGACGCCACC
ACGGTGAAGCCGCGCGTGCTGACGATCACGCAGTCCACCTACGACGGCGTGCTCTACAACACCGAGACCATCAAGTCGAT
GATGGACGGCTACGTGGACAACCTGCACTTCGACGAGGCCTGGCTGCCGCATGCGGCCTTCCATCCGTTCTACGGCAGCT
ACCACGCCATGGGCAAGAAGCGCGCGCGCCCGAAGCATTCGGTGGTGTATGCGACGCAGTCCATCCACAAGCTGCTGGCC
GGCATCAGCCAGGCGAGCCACGTACTGGTGCAGGATTCGCAGACGGTGAAACTGGACCGCCCGCTCTTCAACGAGGCGTA
CCTGATGCACACCTCGACCAGCCCGCAGTACAGCATCATCGCCAGCTGCGACGTGGCCGCGGCCATGATGGAGCCGCCCG
GCGGCACGGCGCTCGTGGAAGAGAGCCTGCTCGAAGCCCTGGATTTCCGCCGCGCCATGCGCAAGGTGGAAGAGGAGTTC
GGCAAGGACGACTGGTGGTTCAAGGTCTGGGGCCCGGAGAAGATGGCCGACGAGGGCGTGGGCCGCGCGGAGGACTGGAT
CATCCGCAGCGACGGCAAGGGCAAAAAGAACGGCAGCAAGTGGCACGGCTTCGGCCAGCTGGCCGACGGCTTCAACATGC
TGGACCCGATCAAGTCCACCATCGTCACGCCCGGCCTGAACCTGGACGGCAAGTTCGACAAGACCGGCATTCCCGCGTCC
ATCGTGACCAAGTACCTGGCCGAGCACGGCGTGGTGGTGGAGAAGACGGGGCTCTACAGCTTCTTCATCATGTTCACCAT
CGGCATCACCAAGGGCCGCTGGAACACGCTGCTGGCCGCGCTGCAGCAGTTCAAGGACGACTACGAGAAGAACCAGCCGA
TGTGGCGGATCCTTCCGGAGTTCTGCCAGCAGCACAAGCGCTACGAGCGCATGGGCCTGAAGGACCTGTGCCAGCACGTG
CATGCGCTCTACGCCAAGTACGACATCGCGCGGCTGACGACCGAGATGTACCTGTCGGACCTGACGCCGGCGATGAAGCC
CAGCGACGCCTATGCCCACATCGCGCACCGCAAGACCGAGCGCGTGGAGATCGACCACCTGGAAGGCCGCATCACCACCA
GCCTGATCACGCCGTACCCGCCGGGGATTCCGCTGCTGATCCCGGGCGAGGTCTTCAACAAGAAGATCGTGGACTACCTC
AAATTCGCGCGCGAGTTCGCCAAGCTCTGTCCGGGCTTCGAGACCGACATCCACGGCCTGGTGGAGATCGAGGACGACAA
CGGCCACGTGCGCTACTACGCCGATTGCGTGACCCGGACCGAGCAGCCCAAGCCCGGCCGCCGCGGCGGCCGCAAGGACG
CGCCCGACGCCGAGGACATCGTGCAGGTGGGCAGCGACGGGCCGTTCGGCCGGAAGATCTGA

Upstream 100 bases:

>100_bases
ATTCTGGGTCAAATGCCGATGTCTTCAAAGGGATGACATCGTTATTCCTTACACTTCGCGGCTGTTTCGTTTTTTGGGCC
CGCTTGCTCGGAGGCTGTGC

Downstream 100 bases:

>100_bases
TCGCCACGCACGGCGGAGCGTACCGCTCGCGGAAGCCCGGTGGCGTGAAGGCGCCTCCGGGCTTTCTTGCATGGAATGGG
TACCGGGCTTGATCCAGGCG

Product: lysine decarboxylase

Products: NA

Alternate protein names: ADC [H]

Number of amino acids: Translated: 793; Mature: 793

Protein sequence:

>793_residues
MKFRFPIVIIDEDYRSENTSGLGIRALAQAIEAEGFEVLGVTSYGDLSQFAQQQSRASAFILSIDDEEFTLGSGLDPIVL
SLRNFIAQVRRKNSDVPIYVHGETKTARHLPNDILRELHGFIHMFEDTPEFVAKHIIREAKSYLESVQPPFFKALLDYAE
DGSYSWHCPGHSGGVAFLKSPVGQMFHQFFGENMLRADVCNAVEELGQLLDHNGAIGESERNAARIFNADHCFFVTNGTS
TSNKMVWHHTVAPGDVVVVDRNCHKSILHSIIMTGAIPVFLKPTRNHFGIIGPIPQAEFEKEAIQAKIRANPLLKGVDAT
TVKPRVLTITQSTYDGVLYNTETIKSMMDGYVDNLHFDEAWLPHAAFHPFYGSYHAMGKKRARPKHSVVYATQSIHKLLA
GISQASHVLVQDSQTVKLDRPLFNEAYLMHTSTSPQYSIIASCDVAAAMMEPPGGTALVEESLLEALDFRRAMRKVEEEF
GKDDWWFKVWGPEKMADEGVGRAEDWIIRSDGKGKKNGSKWHGFGQLADGFNMLDPIKSTIVTPGLNLDGKFDKTGIPAS
IVTKYLAEHGVVVEKTGLYSFFIMFTIGITKGRWNTLLAALQQFKDDYEKNQPMWRILPEFCQQHKRYERMGLKDLCQHV
HALYAKYDIARLTTEMYLSDLTPAMKPSDAYAHIAHRKTERVEIDHLEGRITTSLITPYPPGIPLLIPGEVFNKKIVDYL
KFAREFAKLCPGFETDIHGLVEIEDDNGHVRYYADCVTRTEQPKPGRRGGRKDAPDAEDIVQVGSDGPFGRKI

Sequences:

>Translated_793_residues
MKFRFPIVIIDEDYRSENTSGLGIRALAQAIEAEGFEVLGVTSYGDLSQFAQQQSRASAFILSIDDEEFTLGSGLDPIVL
SLRNFIAQVRRKNSDVPIYVHGETKTARHLPNDILRELHGFIHMFEDTPEFVAKHIIREAKSYLESVQPPFFKALLDYAE
DGSYSWHCPGHSGGVAFLKSPVGQMFHQFFGENMLRADVCNAVEELGQLLDHNGAIGESERNAARIFNADHCFFVTNGTS
TSNKMVWHHTVAPGDVVVVDRNCHKSILHSIIMTGAIPVFLKPTRNHFGIIGPIPQAEFEKEAIQAKIRANPLLKGVDAT
TVKPRVLTITQSTYDGVLYNTETIKSMMDGYVDNLHFDEAWLPHAAFHPFYGSYHAMGKKRARPKHSVVYATQSIHKLLA
GISQASHVLVQDSQTVKLDRPLFNEAYLMHTSTSPQYSIIASCDVAAAMMEPPGGTALVEESLLEALDFRRAMRKVEEEF
GKDDWWFKVWGPEKMADEGVGRAEDWIIRSDGKGKKNGSKWHGFGQLADGFNMLDPIKSTIVTPGLNLDGKFDKTGIPAS
IVTKYLAEHGVVVEKTGLYSFFIMFTIGITKGRWNTLLAALQQFKDDYEKNQPMWRILPEFCQQHKRYERMGLKDLCQHV
HALYAKYDIARLTTEMYLSDLTPAMKPSDAYAHIAHRKTERVEIDHLEGRITTSLITPYPPGIPLLIPGEVFNKKIVDYL
KFAREFAKLCPGFETDIHGLVEIEDDNGHVRYYADCVTRTEQPKPGRRGGRKDAPDAEDIVQVGSDGPFGRKI
>Mature_793_residues
MKFRFPIVIIDEDYRSENTSGLGIRALAQAIEAEGFEVLGVTSYGDLSQFAQQQSRASAFILSIDDEEFTLGSGLDPIVL
SLRNFIAQVRRKNSDVPIYVHGETKTARHLPNDILRELHGFIHMFEDTPEFVAKHIIREAKSYLESVQPPFFKALLDYAE
DGSYSWHCPGHSGGVAFLKSPVGQMFHQFFGENMLRADVCNAVEELGQLLDHNGAIGESERNAARIFNADHCFFVTNGTS
TSNKMVWHHTVAPGDVVVVDRNCHKSILHSIIMTGAIPVFLKPTRNHFGIIGPIPQAEFEKEAIQAKIRANPLLKGVDAT
TVKPRVLTITQSTYDGVLYNTETIKSMMDGYVDNLHFDEAWLPHAAFHPFYGSYHAMGKKRARPKHSVVYATQSIHKLLA
GISQASHVLVQDSQTVKLDRPLFNEAYLMHTSTSPQYSIIASCDVAAAMMEPPGGTALVEESLLEALDFRRAMRKVEEEF
GKDDWWFKVWGPEKMADEGVGRAEDWIIRSDGKGKKNGSKWHGFGQLADGFNMLDPIKSTIVTPGLNLDGKFDKTGIPAS
IVTKYLAEHGVVVEKTGLYSFFIMFTIGITKGRWNTLLAALQQFKDDYEKNQPMWRILPEFCQQHKRYERMGLKDLCQHV
HALYAKYDIARLTTEMYLSDLTPAMKPSDAYAHIAHRKTERVEIDHLEGRITTSLITPYPPGIPLLIPGEVFNKKIVDYL
KFAREFAKLCPGFETDIHGLVEIEDDNGHVRYYADCVTRTEQPKPGRRGGRKDAPDAEDIVQVGSDGPFGRKI

Specific function: ADC can be found in two forms:biodegradative and biosynthetic. The biodegradative form may play a role in regulating pH by consuming proteins [H]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI221142684, Length=760, Percent_Identity=37.1052631578947, Blast_Score=515, Evalue=1e-147,
Organism=Escherichia coli, GI1790573, Length=720, Percent_Identity=38.3333333333333, Blast_Score=511, Evalue=1e-146,
Organism=Escherichia coli, GI1786384, Length=732, Percent_Identity=37.431693989071, Blast_Score=491, Evalue=1e-140,
Organism=Escherichia coli, GI1786909, Length=686, Percent_Identity=31.6326530612245, Blast_Score=355, Evalue=9e-99,
Organism=Escherichia coli, GI87082193, Length=706, Percent_Identity=31.728045325779, Blast_Score=345, Evalue=5e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.19 [H]

Molecular weight: Translated: 89036; Mature: 89036

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFRFPIVIIDEDYRSENTSGLGIRALAQAIEAEGFEVLGVTSYGDLSQFAQQQSRASAF
CCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCEEE
ILSIDDEEFTLGSGLDPIVLSLRNFIAQVRRKNSDVPIYVHGETKTARHLPNDILRELHG
EEEECCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHCCCHHHHHHHHH
FIHMFEDTPEFVAKHIIREAKSYLESVQPPFFKALLDYAEDGSYSWHCPGHSGGVAFLKS
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHH
PVGQMFHQFFGENMLRADVCNAVEELGQLLDHNGAIGESERNAARIFNADHCFFVTNGTS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEECCCEEEEEECCCC
TSNKMVWHHTVAPGDVVVVDRNCHKSILHSIIMTGAIPVFLKPTRNHFGIIGPIPQAEFE
CCCCEEEEEECCCCCEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCEECCCCCHHHH
KEAIQAKIRANPLLKGVDATTVKPRVLTITQSTYDGVLYNTETIKSMMDGYVDNLHFDEA
HHHHHHHHHCCCHHCCCCCCCCCCEEEEEECCCCCCEEECHHHHHHHHHHHHHCCCCCCC
WLPHAAFHPFYGSYHAMGKKRARPKHSVVYATQSIHKLLAGISQASHVLVQDSQTVKLDR
CCCCHHCCCCCCCHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHCEEEEECCCEEEECC
PLFNEAYLMHTSTSPQYSIIASCDVAAAMMEPPGGTALVEESLLEALDFRRAMRKVEEEF
CCCCCEEEEECCCCCCEEEEEECHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GKDDWWFKVWGPEKMADEGVGRAEDWIIRSDGKGKKNGSKWHGFGQLADGFNMLDPIKST
CCCCCEEEEECCHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHCCCCHHHHHHHH
IVTPGLNLDGKFDKTGIPASIVTKYLAEHGVVVEKTGLYSFFIMFTIGITKGRWNTLLAA
HCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHH
LQQFKDDYEKNQPMWRILPEFCQQHKRYERMGLKDLCQHVHALYAKYDIARLTTEMYLSD
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTPAMKPSDAYAHIAHRKTERVEIDHLEGRITTSLITPYPPGIPLLIPGEVFNKKIVDYL
CCCCCCCCHHHHHHHHCCCCCEEEECCCCEEEEEEECCCCCCCCEEECHHHHHHHHHHHH
KFAREFAKLCPGFETDIHGLVEIEDDNGHVRYYADCVTRTEQPKPGRRGGRKDAPDAEDI
HHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEEHHCCCCCCCCCCCCCCCCCCCHHHH
VQVGSDGPFGRKI
HHCCCCCCCCCCC
>Mature Secondary Structure
MKFRFPIVIIDEDYRSENTSGLGIRALAQAIEAEGFEVLGVTSYGDLSQFAQQQSRASAF
CCEEEEEEEECCCCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCEEE
ILSIDDEEFTLGSGLDPIVLSLRNFIAQVRRKNSDVPIYVHGETKTARHLPNDILRELHG
EEEECCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHCCCHHHHHHHHH
FIHMFEDTPEFVAKHIIREAKSYLESVQPPFFKALLDYAEDGSYSWHCPGHSGGVAFLKS
HHHHHCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEECCCCCCCHHHHHH
PVGQMFHQFFGENMLRADVCNAVEELGQLLDHNGAIGESERNAARIFNADHCFFVTNGTS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEECCCEEEEEECCCC
TSNKMVWHHTVAPGDVVVVDRNCHKSILHSIIMTGAIPVFLKPTRNHFGIIGPIPQAEFE
CCCCEEEEEECCCCCEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCCCEECCCCCHHHH
KEAIQAKIRANPLLKGVDATTVKPRVLTITQSTYDGVLYNTETIKSMMDGYVDNLHFDEA
HHHHHHHHHCCCHHCCCCCCCCCCEEEEEECCCCCCEEECHHHHHHHHHHHHHCCCCCCC
WLPHAAFHPFYGSYHAMGKKRARPKHSVVYATQSIHKLLAGISQASHVLVQDSQTVKLDR
CCCCHHCCCCCCCHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHCEEEEECCCEEEECC
PLFNEAYLMHTSTSPQYSIIASCDVAAAMMEPPGGTALVEESLLEALDFRRAMRKVEEEF
CCCCCEEEEECCCCCCEEEEEECHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
GKDDWWFKVWGPEKMADEGVGRAEDWIIRSDGKGKKNGSKWHGFGQLADGFNMLDPIKST
CCCCCEEEEECCHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHCCCCHHHHHHHH
IVTPGLNLDGKFDKTGIPASIVTKYLAEHGVVVEKTGLYSFFIMFTIGITKGRWNTLLAA
HCCCCCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCHHHHHHHHHHHCCCCHHHHHHHH
LQQFKDDYEKNQPMWRILPEFCQQHKRYERMGLKDLCQHVHALYAKYDIARLTTEMYLSD
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTPAMKPSDAYAHIAHRKTERVEIDHLEGRITTSLITPYPPGIPLLIPGEVFNKKIVDYL
CCCCCCCCHHHHHHHHCCCCCEEEECCCCEEEEEEECCCCCCCCEEECHHHHHHHHHHHH
KFAREFAKLCPGFETDIHGLVEIEDDNGHVRYYADCVTRTEQPKPGRRGGRKDAPDAEDI
HHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEEHHCCCCCCCCCCCCCCCCCCCHHHH
VQVGSDGPFGRKI
HHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8383109; 7610040; 9278503; 2830169; 4204273 [H]