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The map label for this gene is glcD [H]

Identifier: 120611867

GI number: 120611867

Start: 3538289

End: 3539758

Strand: Direct

Name: glcD [H]

Synonym: Aave_3209

Alternate gene names: 120611867

Gene position: 3538289-3539758 (Clockwise)

Preceding gene: 120611864

Following gene: 120611868

Centisome position: 66.1

GC content: 72.86

Gene sequence:

>1470_bases
ATGCGCGCCACCGTGACCGATCCCTCCCTGCCCGCCACGCTGGCCGCCATCGTGGGCGCCACGCACGTGCTCACCGCCCC
GGAAGACATGGCCCGCTACGAGGCCGAATGGCGCGGCACCTACCCGGGCGCTGCGCGCGCCGTGGTGCGGCCCGCCACGA
CCGGCGAGGTGTCCCGCGTGGTCGCCGCGTGCGCCGCCGCCGGCGCGTGCATCGTGCCGCAGGGGGGCAACACCGGCCTG
GTGGGCGGCTCCACCCCGGACGACTCCAGGACCGAGGTGGTGCTGAGCCTGGAGCGCATGCGCACGGTGCGCCGCAGCGA
CCCGCTGGACAACACGCTGACGGTGGAGGCCGGCTGCACGGTGCTGGCCGCGCAGGAGGCGGCGGCGTCCGTGGGCCGGC
TGTTCCCGCTGTCGCTGGCCTCGGAAGGCAGCGCCACCGTGGGCGGCGTGGTGTCCACCAACGCGGGGGGCGAGCAGGTG
CTGCGCTACGGCAATACCCGCGACCTGGTGCTGGGACTGGAGGCGGTGCTGGCCGACGGGCGCGTGCTGAACCTGCTGGG
CGCGCTGCGCAAGGACAACACGGGCTACGACCTCAAGCAGCTCTTCATCGGTGGCGAGGGCACGCTGGGCATCGTCACCG
CCGTCACGTTCAAGCTGTTCGCGCGTCCGCGCAACGTGGTGACGGCATGGGTGGCCGTGCGCGACCCGCGGGCGGCCGTG
GAGCTGCTGTCGCGCCTGACCGATGCGGTGGGCGAGCGCGTCACCGCCTTCGAGCTGATCGGCGACGGCCCGCTGGGCCT
GGTGCTGCGGCACGGCACGGCCGGCATGCGCTGCCCGCTCGGCGAGGTGCCGGCATGGTCGGTGCTGTTCGACGTGTCCG
AGGTGTCGGCCCGGATGGATCCCGCCCCCGCGGTGGAAGACGTGCTGGGCGCGGCGATGGAGGACGGGCTGGTGCAAGAC
GCCGCGCTGGCCGCTTCGGACAGCCAGGCCCATGCTTTCTGGGCGCTGCGCGAGCATGTGCCCGAGGCGCAGCGGCTGGA
GGGTCCGTCGATCAAGCACGACATCGCGGTGGCGATTTCGCGCATTCCGCAATTCATCGGCGAAGCCGGCGCGGCGCTGC
AGGCCTTCATGCCCGGCGTGCGCATCGTGTGCTTCGGCCACGTGGGCGACGGCAACCTGCACTACAACCAGAGCCTGCCC
CCGGGCATGGCGCCGGCGGATTTCCGCGCGCAGGAAGACGCGATCCACGACATCGTGCATGCCACGGCCGCCCGGCTGGG
CGGCTCGATCTCGGCCGAACACGGCATCGGCCGCCAGAAGCAGCAGGCGCTGCTGCACTACAAGAGCCCCGTCGCCCTGG
AGGCGATGGCGCGCATCAAGCGGGCCATGGACCCGCGCAACACATTCAACCCGGGCCGCATGCTGCCGCGCGCGCTCGTG
GAAGCCACCGCGTCCCTTTCCGACCACTGA

Upstream 100 bases:

>100_bases
TTAATAACTGAAATGTATTTCATTCATTGAAATACCGCAAGCCAATCAACGCCCCCCTCCATTGCCGCGCCACCGATGGT
AGCGGCCGACCTGCACCGAC

Downstream 100 bases:

>100_bases
ACCCCGACACTCCGACAGGACACCCATGCCCGTTTCCGTATTCGACATGCAGTCGCTCCAGCACCTCTGGGGCACCGACG
AGTTGCGCACCATCTTCGGC

Product: FAD linked oxidase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 489

Protein sequence:

>489_residues
MRATVTDPSLPATLAAIVGATHVLTAPEDMARYEAEWRGTYPGAARAVVRPATTGEVSRVVAACAAAGACIVPQGGNTGL
VGGSTPDDSRTEVVLSLERMRTVRRSDPLDNTLTVEAGCTVLAAQEAAASVGRLFPLSLASEGSATVGGVVSTNAGGEQV
LRYGNTRDLVLGLEAVLADGRVLNLLGALRKDNTGYDLKQLFIGGEGTLGIVTAVTFKLFARPRNVVTAWVAVRDPRAAV
ELLSRLTDAVGERVTAFELIGDGPLGLVLRHGTAGMRCPLGEVPAWSVLFDVSEVSARMDPAPAVEDVLGAAMEDGLVQD
AALAASDSQAHAFWALREHVPEAQRLEGPSIKHDIAVAISRIPQFIGEAGAALQAFMPGVRIVCFGHVGDGNLHYNQSLP
PGMAPADFRAQEDAIHDIVHATAARLGGSISAEHGIGRQKQQALLHYKSPVALEAMARIKRAMDPRNTFNPGRMLPRALV
EATASLSDH

Sequences:

>Translated_489_residues
MRATVTDPSLPATLAAIVGATHVLTAPEDMARYEAEWRGTYPGAARAVVRPATTGEVSRVVAACAAAGACIVPQGGNTGL
VGGSTPDDSRTEVVLSLERMRTVRRSDPLDNTLTVEAGCTVLAAQEAAASVGRLFPLSLASEGSATVGGVVSTNAGGEQV
LRYGNTRDLVLGLEAVLADGRVLNLLGALRKDNTGYDLKQLFIGGEGTLGIVTAVTFKLFARPRNVVTAWVAVRDPRAAV
ELLSRLTDAVGERVTAFELIGDGPLGLVLRHGTAGMRCPLGEVPAWSVLFDVSEVSARMDPAPAVEDVLGAAMEDGLVQD
AALAASDSQAHAFWALREHVPEAQRLEGPSIKHDIAVAISRIPQFIGEAGAALQAFMPGVRIVCFGHVGDGNLHYNQSLP
PGMAPADFRAQEDAIHDIVHATAARLGGSISAEHGIGRQKQQALLHYKSPVALEAMARIKRAMDPRNTFNPGRMLPRALV
EATASLSDH
>Mature_489_residues
MRATVTDPSLPATLAAIVGATHVLTAPEDMARYEAEWRGTYPGAARAVVRPATTGEVSRVVAACAAAGACIVPQGGNTGL
VGGSTPDDSRTEVVLSLERMRTVRRSDPLDNTLTVEAGCTVLAAQEAAASVGRLFPLSLASEGSATVGGVVSTNAGGEQV
LRYGNTRDLVLGLEAVLADGRVLNLLGALRKDNTGYDLKQLFIGGEGTLGIVTAVTFKLFARPRNVVTAWVAVRDPRAAV
ELLSRLTDAVGERVTAFELIGDGPLGLVLRHGTAGMRCPLGEVPAWSVLFDVSEVSARMDPAPAVEDVLGAAMEDGLVQD
AALAASDSQAHAFWALREHVPEAQRLEGPSIKHDIAVAISRIPQFIGEAGAALQAFMPGVRIVCFGHVGDGNLHYNQSLP
PGMAPADFRAQEDAIHDIVHATAARLGGSISAEHGIGRQKQQALLHYKSPVALEAMARIKRAMDPRNTFNPGRMLPRALV
EATASLSDH

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI119964728, Length=454, Percent_Identity=37.4449339207048, Blast_Score=271, Evalue=7e-73,
Organism=Homo sapiens, GI37595756, Length=471, Percent_Identity=31.4225053078556, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI37595754, Length=494, Percent_Identity=29.9595141700405, Blast_Score=151, Evalue=1e-36,
Organism=Homo sapiens, GI4501993, Length=178, Percent_Identity=32.0224719101124, Blast_Score=74, Evalue=5e-13,
Organism=Escherichia coli, GI1789351, Length=472, Percent_Identity=28.3898305084746, Blast_Score=129, Evalue=6e-31,
Organism=Escherichia coli, GI1787977, Length=504, Percent_Identity=23.8095238095238, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI48994907, Length=514, Percent_Identity=24.124513618677, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1788454, Length=165, Percent_Identity=33.9393939393939, Blast_Score=72, Evalue=8e-14,
Organism=Escherichia coli, GI48994914, Length=125, Percent_Identity=32, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17534361, Length=453, Percent_Identity=30.6843267108168, Blast_Score=224, Evalue=9e-59,
Organism=Caenorhabditis elegans, GI71992373, Length=489, Percent_Identity=28.6298568507157, Blast_Score=144, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI71992381, Length=497, Percent_Identity=27.7665995975855, Blast_Score=135, Evalue=7e-32,
Organism=Caenorhabditis elegans, GI71992392, Length=377, Percent_Identity=28.9124668435013, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17556096, Length=196, Percent_Identity=28.0612244897959, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320023, Length=472, Percent_Identity=33.0508474576271, Blast_Score=278, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6320764, Length=485, Percent_Identity=33.8144329896907, Blast_Score=270, Evalue=5e-73,
Organism=Saccharomyces cerevisiae, GI6320027, Length=438, Percent_Identity=27.6255707762557, Blast_Score=149, Evalue=1e-36,
Organism=Drosophila melanogaster, GI18921117, Length=475, Percent_Identity=34.7368421052632, Blast_Score=258, Evalue=6e-69,
Organism=Drosophila melanogaster, GI24639277, Length=475, Percent_Identity=34.7368421052632, Blast_Score=258, Evalue=6e-69,
Organism=Drosophila melanogaster, GI24639275, Length=475, Percent_Identity=34.7368421052632, Blast_Score=258, Evalue=6e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 51231; Mature: 51231

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRATVTDPSLPATLAAIVGATHVLTAPEDMARYEAEWRGTYPGAARAVVRPATTGEVSRV
CCCCCCCCCCHHHHHHHHHHHHEEECCHHHHHHHHHCCCCCCCCCCCEECCCCCHHHHHH
VAACAAAGACIVPQGGNTGLVGGSTPDDSRTEVVLSLERMRTVRRSDPLDNTLTVEAGCT
HHHHHHCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCE
VLAAQEAAASVGRLFPLSLASEGSATVGGVVSTNAGGEQVLRYGNTRDLVLGLEAVLADG
EEEHHHHHHHHHCCCEEEECCCCCCCCCCEEECCCCHHHHHHCCCCCHHHHHHHHHHHCC
RVLNLLGALRKDNTGYDLKQLFIGGEGTLGIVTAVTFKLFARPRNVVTAWVAVRDPRAAV
HHHHHHHHHHCCCCCCCHHHEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHH
ELLSRLTDAVGERVTAFELIGDGPLGLVLRHGTAGMRCPLGEVPAWSVLFDVSEVSARMD
HHHHHHHHHHCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCHHHEEEHHHHHHCCC
PAPAVEDVLGAAMEDGLVQDAALAASDSQAHAFWALREHVPEAQRLEGPSIKHDIAVAIS
CCCHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHH
RIPQFIGEAGAALQAFMPGVRIVCFGHVGDGNLHYNQSLPPGMAPADFRAQEDAIHDIVH
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHH
ATAARLGGSISAEHGIGRQKQQALLHYKSPVALEAMARIKRAMDPRNTFNPGRMLPRALV
HHHHHHCCCCCHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
EATASLSDH
HHHHHCCCC
>Mature Secondary Structure
MRATVTDPSLPATLAAIVGATHVLTAPEDMARYEAEWRGTYPGAARAVVRPATTGEVSRV
CCCCCCCCCCHHHHHHHHHHHHEEECCHHHHHHHHHCCCCCCCCCCCEECCCCCHHHHHH
VAACAAAGACIVPQGGNTGLVGGSTPDDSRTEVVLSLERMRTVRRSDPLDNTLTVEAGCT
HHHHHHCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCE
VLAAQEAAASVGRLFPLSLASEGSATVGGVVSTNAGGEQVLRYGNTRDLVLGLEAVLADG
EEEHHHHHHHHHCCCEEEECCCCCCCCCCEEECCCCHHHHHHCCCCCHHHHHHHHHHHCC
RVLNLLGALRKDNTGYDLKQLFIGGEGTLGIVTAVTFKLFARPRNVVTAWVAVRDPRAAV
HHHHHHHHHHCCCCCCCHHHEEECCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHH
ELLSRLTDAVGERVTAFELIGDGPLGLVLRHGTAGMRCPLGEVPAWSVLFDVSEVSARMD
HHHHHHHHHHCCCEEEEEEECCCCEEEEEECCCCCCCCCCCCCCCHHHEEEHHHHHHCCC
PAPAVEDVLGAAMEDGLVQDAALAASDSQAHAFWALREHVPEAQRLEGPSIKHDIAVAIS
CCCHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHH
RIPQFIGEAGAALQAFMPGVRIVCFGHVGDGNLHYNQSLPPGMAPADFRAQEDAIHDIVH
HHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEECCCCCCCCCCCCCCHHHHHHHHHHH
ATAARLGGSISAEHGIGRQKQQALLHYKSPVALEAMARIKRAMDPRNTFNPGRMLPRALV
HHHHHHCCCCCHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHH
EATASLSDH
HHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]