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The map label for this gene is insF1 [C]

Identifier: 120611375

GI number: 120611375

Start: 2977430

End: 2978329

Strand: Reverse

Name: insF1 [C]

Synonym: Aave_2709

Alternate gene names: 120611375

Gene position: 2978329-2977430 (Counterclockwise)

Preceding gene: 120611380

Following gene: 120611368

Centisome position: 55.64

GC content: 66.89

Gene sequence:

>900_bases
ATGACGGGGTTCATCGACGAACACCGCGCCAGGTACGGAGTCGAGCCGATCTGCAGGGTGCTGCCGATCGCTCCGTCGAC
CTACTACACGCACGCGGCTCGGCAGGCCGATCCGGAACTGCAGCCGAACCGCTGGTGGCGCGACCGCGCCATGGAGGCGG
AGGTTCGCCGGGTCTGGGACGAGAACAAGCAAGTCTACGGCGTGCGCAAGGTCTGGAAGCAGCTGTGCCGGGAAGGCTAC
CGGGTGGCGCGTTGCACGGTGGCACGACTGATGAAGCGGTTGGGCCTGCGCGGGGTCGTTCGCGGCAAGGTCGTGAAGAC
CAAACACAGCGACAAGGCGGTGCCGTGCCCGCGCGACCAGGTGAACCGGCAGTTCCGCGCCGACCGGCCCAACGCGCTGT
GGGTGAGCGACTTCACCTACGTCTCGACCTGGGCGGGTTTCGTGTACGTGGCCTTCGTGATCGACGTGTACGCCCGCCGG
ATCGTAGGCTGGAAGGTCTCCGGCTCGGCCCGGACCGACTTCGTCCTGGACGCGCTGGAGCAGGCACTCCACGCTCGTCG
CCCGACGCGGGGCGGGCTGATCCACCACAGCGATCGCGGCGTGCAGTACGTGTCGATCCGCTACACCGAGCGTCTGGCCG
AGGCCGGCATCGAGCCCTCGGTGGGCAGTGTCGGCGACAGCTACGACAATGCACTGGCCGAGACGATCAACGGCCTGTAC
AAGGCCGAGGTCATCCATCGGCGGTCCTGGAGGAACCTGCAGGACGTCGAACTGGCCACGCTGGAGTGGGTGGGCTGGTT
CAACCACAAGCGCCTGCTTGGCCCGATCGGCGACATCCCACCGGCCGAAGCAGAAGCGAACTACTATCAGCAGACTCGTG
AGATCGCCATGGCGGCGTGA

Upstream 100 bases:

>100_bases
TGCTGGAGCGTGAGAACCGCGAACTGCGCCAGGCCAACGAGATTCTGCGCAAGGCGTCGGCGTATTTTGCCCAGGCGGAG
CTCGACCGCCGGTTCAAGCC

Downstream 100 bases:

>100_bases
CTCACACCAACGAGTCTCCGGAAATCCCGGGGCGGTTCAGCCGACCCTCTACTTCAGTCCTGGTGTCGTGATGGGTGATC
TGGCTGTGCTCCACATGTTA

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MTGFIDEHRARYGVEPICRVLPIAPSTYYTHAARQADPELQPNRWWRDRAMEAEVRRVWDENKQVYGVRKVWKQLCREGY
RVARCTVARLMKRLGLRGVVRGKVVKTKHSDKAVPCPRDQVNRQFRADRPNALWVSDFTYVSTWAGFVYVAFVIDVYARR
IVGWKVSGSARTDFVLDALEQALHARRPTRGGLIHHSDRGVQYVSIRYTERLAEAGIEPSVGSVGDSYDNALAETINGLY
KAEVIHRRSWRNLQDVELATLEWVGWFNHKRLLGPIGDIPPAEAEANYYQQTREIAMAA

Sequences:

>Translated_299_residues
MTGFIDEHRARYGVEPICRVLPIAPSTYYTHAARQADPELQPNRWWRDRAMEAEVRRVWDENKQVYGVRKVWKQLCREGY
RVARCTVARLMKRLGLRGVVRGKVVKTKHSDKAVPCPRDQVNRQFRADRPNALWVSDFTYVSTWAGFVYVAFVIDVYARR
IVGWKVSGSARTDFVLDALEQALHARRPTRGGLIHHSDRGVQYVSIRYTERLAEAGIEPSVGSVGDSYDNALAETINGLY
KAEVIHRRSWRNLQDVELATLEWVGWFNHKRLLGPIGDIPPAEAEANYYQQTREIAMAA
>Mature_298_residues
TGFIDEHRARYGVEPICRVLPIAPSTYYTHAARQADPELQPNRWWRDRAMEAEVRRVWDENKQVYGVRKVWKQLCREGYR
VARCTVARLMKRLGLRGVVRGKVVKTKHSDKAVPCPRDQVNRQFRADRPNALWVSDFTYVSTWAGFVYVAFVIDVYARRI
VGWKVSGSARTDFVLDALEQALHARRPTRGGLIHHSDRGVQYVSIRYTERLAEAGIEPSVGSVGDSYDNALAETINGLYK
AEVIHRRSWRNLQDVELATLEWVGWFNHKRLLGPIGDIPPAEAEANYYQQTREIAMAA

Specific function: Involved in the transposition of the insertion sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=245, Percent_Identity=57.9591836734694, Blast_Score=279, Evalue=2e-75,
Organism=Escherichia coli, GI1788405, Length=243, Percent_Identity=32.0987654320988, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1787263, Length=243, Percent_Identity=32.0987654320988, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1786753, Length=243, Percent_Identity=32.0987654320988, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1786570, Length=243, Percent_Identity=32.0987654320988, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1786490, Length=243, Percent_Identity=32.0987654320988, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1789981, Length=279, Percent_Identity=27.2401433691756, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 34369; Mature: 34237

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGFIDEHRARYGVEPICRVLPIAPSTYYTHAARQADPELQPNRWWRDRAMEAEVRRVWD
CCCCCCHHHHHCCCCHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
ENKQVYGVRKVWKQLCREGYRVARCTVARLMKRLGLRGVVRGKVVKTKHSDKAVPCPRDQ
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHCCCEEEECCCCCCCCCCHHH
VNRQFRADRPNALWVSDFTYVSTWAGFVYVAFVIDVYARRIVGWKVSGSARTDFVLDALE
HHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCHHHHHHHHH
QALHARRPTRGGLIHHSDRGVQYVSIRYTERLAEAGIEPSVGSVGDSYDNALAETINGLY
HHHHHCCCCCCCCEEECCCCEEEEEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
KAEVIHRRSWRNLQDVELATLEWVGWFNHKRLLGPIGDIPPAEAEANYYQQTREIAMAA
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TGFIDEHRARYGVEPICRVLPIAPSTYYTHAARQADPELQPNRWWRDRAMEAEVRRVWD
CCCCCHHHHHCCCCHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
ENKQVYGVRKVWKQLCREGYRVARCTVARLMKRLGLRGVVRGKVVKTKHSDKAVPCPRDQ
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHCCCEEEECCCCCCCCCCHHH
VNRQFRADRPNALWVSDFTYVSTWAGFVYVAFVIDVYARRIVGWKVSGSARTDFVLDALE
HHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCHHHHHHHHH
QALHARRPTRGGLIHHSDRGVQYVSIRYTERLAEAGIEPSVGSVGDSYDNALAETINGLY
HHHHHCCCCCCCCEEECCCCEEEEEEHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
KAEVIHRRSWRNLQDVELATLEWVGWFNHKRLLGPIGDIPPAEAEANYYQQTREIAMAA
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2159625; 2824781 [H]