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The map label for this gene is ppa [H]

Identifier: 120611337

GI number: 120611337

Start: 2930700

End: 2931236

Strand: Direct

Name: ppa [H]

Synonym: Aave_2669

Alternate gene names: 120611337

Gene position: 2930700-2931236 (Clockwise)

Preceding gene: 120611334

Following gene: 120611338

Centisome position: 54.75

GC content: 62.01

Gene sequence:

>537_bases
ATGTCCCTCAACAACGTCACCCCTGGCAAGAAGCTTCCCGAAAACTTCAACGTGGTCATCGAGATTCCCGCGGAATCCGA
CCCGATCAAGTACGAAGTGGACAAGGAATCCGGCGCGGTCTTCGTGGACCGCTTCCTGACCACGGCCATGTACTACCCCT
GCAACTACGGCTATGTGCCCCAGACGCTGTCCGGCGACGGCGACCCGGTGGACGTGCTGGTGATCACGCCGTACCCGCTG
CACCCCGGCGTGGTCGTGCCCTGCCGCGCGCTCGGCATCCTGAAGATGGAAGACGAAGCCGGCGTGGACGGCAAGGTGCT
GGCCGTGCCCACCACCAAGATCCTCAAGATGTACGAAGGCTGGAAGACGGTGGACGACGTGAACCCCGTGCGCCTGAAGG
CCATCAGCCATTTCTTCGAGCACTACAAGGACCTGGAAGAGGGCAAGTGGGTCAAGGTGCTGGGCTGGGAAGGCGTCGAT
GCCGCCCACAAGGAAATCACCGACGGCGTCGCCAATTACCAGAAGTCCCAGGGCTGA

Upstream 100 bases:

>100_bases
CCTGCAGGCGCGCCGCCGCAAGCGATGCGCCACGCGCGGACCGGGAGGCGCGCATCCGCCGCTCTAGAATGCGCCCCTGC
ATTCCATCACCATCCCAACC

Downstream 100 bases:

>100_bases
TGCCCCGGGGCGGGTGGCCCCGCCCCTTGCCGGCGCGCGGCCGGTACCCTGGAAAAGCCTGCCGGCTGTGCGCCCGCAGG
CTTTTTTTGCGCCCGCGGGG

Product: inorganic diphosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase [H]

Number of amino acids: Translated: 178; Mature: 177

Protein sequence:

>178_residues
MSLNNVTPGKKLPENFNVVIEIPAESDPIKYEVDKESGAVFVDRFLTTAMYYPCNYGYVPQTLSGDGDPVDVLVITPYPL
HPGVVVPCRALGILKMEDEAGVDGKVLAVPTTKILKMYEGWKTVDDVNPVRLKAISHFFEHYKDLEEGKWVKVLGWEGVD
AAHKEITDGVANYQKSQG

Sequences:

>Translated_178_residues
MSLNNVTPGKKLPENFNVVIEIPAESDPIKYEVDKESGAVFVDRFLTTAMYYPCNYGYVPQTLSGDGDPVDVLVITPYPL
HPGVVVPCRALGILKMEDEAGVDGKVLAVPTTKILKMYEGWKTVDDVNPVRLKAISHFFEHYKDLEEGKWVKVLGWEGVD
AAHKEITDGVANYQKSQG
>Mature_177_residues
SLNNVTPGKKLPENFNVVIEIPAESDPIKYEVDKESGAVFVDRFLTTAMYYPCNYGYVPQTLSGDGDPVDVLVITPYPLH
PGVVVPCRALGILKMEDEAGVDGKVLAVPTTKILKMYEGWKTVDDVNPVRLKAISHFFEHYKDLEEGKWVKVLGWEGVDA
AHKEITDGVANYQKSQG

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family [H]

Homologues:

Organism=Escherichia coli, GI1790673, Length=178, Percent_Identity=62.3595505617977, Blast_Score=228, Evalue=2e-61,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008162 [H]

Pfam domain/function: PF00719 Pyrophosphatase [H]

EC number: =3.6.1.1 [H]

Molecular weight: Translated: 19728; Mature: 19597

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLNNVTPGKKLPENFNVVIEIPAESDPIKYEVDKESGAVFVDRFLTTAMYYPCNYGYVP
CCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCC
QTLSGDGDPVDVLVITPYPLHPGVVVPCRALGILKMEDEAGVDGKVLAVPTTKILKMYEG
CCCCCCCCCEEEEEECCCCCCCCEEECCCEEEEEEECCCCCCCCEEEEECHHHHHHHHCC
WKTVDDVNPVRLKAISHFFEHYKDLEEGKWVKVLGWEGVDAAHKEITDGVANYQKSQG
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SLNNVTPGKKLPENFNVVIEIPAESDPIKYEVDKESGAVFVDRFLTTAMYYPCNYGYVP
CCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCCCCC
QTLSGDGDPVDVLVITPYPLHPGVVVPCRALGILKMEDEAGVDGKVLAVPTTKILKMYEG
CCCCCCCCCEEEEEECCCCCCCCEEECCCEEEEEEECCCCCCCCEEEEECHHHHHHHHCC
WKTVDDVNPVRLKAISHFFEHYKDLEEGKWVKVLGWEGVDAAHKEITDGVANYQKSQG
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9423859 [H]