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The map label for this gene is rpoE [H]

Identifier: 120611253

GI number: 120611253

Start: 2831816

End: 2832409

Strand: Reverse

Name: rpoE [H]

Synonym: Aave_2585

Alternate gene names: 120611253

Gene position: 2832409-2831816 (Counterclockwise)

Preceding gene: 120611254

Following gene: 120611252

Centisome position: 52.91

GC content: 67.68

Gene sequence:

>594_bases
ATGACCGCTCACTATCCAGACAATTCCCACGACCTTGCACTGCTGCACGCGATCGCGGCGGGCGACCGCGATGCGCTGGC
CACCCTCTATCGCGGCTACCATCGTCGCCTGGGCCAGTTCCTCACCCGCCTCACGCGCCGCACGGACCTGATCGAGGAGA
TCATCAACGACTGCTTCTGGGTGGTCTGGCAGAAGGCCGGCACGTTCCGCGGGGATTCCCGCGTCTCCACCTGGATCATG
GGCATCTCCTACCGCTGCGGACTCAAGGTCCTGCGGCAGAGCGGCGGCCTGGATGCGAGCGACGACGCGGACGACGGAGC
GGCCGCGGAACGGAACCACCCCGGCATCAACCCCGGCGATGACCGCGAGCTGAGGGACTGGCTCGCCAAGGGCCTCGCCC
GGCTGTCGGCGGACCAGCGCCTCGTCCTCGAACTCGCCTACACCCACGGACACTCGATCGAGGAGATCGCCGTCATCACG
CAGGCCCCCGTGGGCACCGTCAAGGCCCGCATGTTCCATGCGCGCGTGAAACTGCGCAACCTGCTGCCCGGACTGGCGGT
AGGCGGCACCGGCACCCAGGATATCCAACCATGA

Upstream 100 bases:

>100_bases
GTCACCGTCATCCGCACCTTCTGACGCGGACCGGCGTGCAACCTTTCCGCTGCACAGGCGCACCCACCGCAACCAGGACG
GCACGTTTTCCCGGTGGCCC

Downstream 100 bases:

>100_bases
CGACACTCCCCCCCGCATCCGCCCATGGCCAGGACCAGGACCGGTCCCACCTGCTCACGCAGGAACTGCTGCCGTGGATC
GTGAACGGCACGGCCACCGA

Product: ECF subfamily RNA polymerase sigma-24 factor

Products: NA

Alternate protein names: Sigma-24 [H]

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MTAHYPDNSHDLALLHAIAAGDRDALATLYRGYHRRLGQFLTRLTRRTDLIEEIINDCFWVVWQKAGTFRGDSRVSTWIM
GISYRCGLKVLRQSGGLDASDDADDGAAAERNHPGINPGDDRELRDWLAKGLARLSADQRLVLELAYTHGHSIEEIAVIT
QAPVGTVKARMFHARVKLRNLLPGLAVGGTGTQDIQP

Sequences:

>Translated_197_residues
MTAHYPDNSHDLALLHAIAAGDRDALATLYRGYHRRLGQFLTRLTRRTDLIEEIINDCFWVVWQKAGTFRGDSRVSTWIM
GISYRCGLKVLRQSGGLDASDDADDGAAAERNHPGINPGDDRELRDWLAKGLARLSADQRLVLELAYTHGHSIEEIAVIT
QAPVGTVKARMFHARVKLRNLLPGLAVGGTGTQDIQP
>Mature_196_residues
TAHYPDNSHDLALLHAIAAGDRDALATLYRGYHRRLGQFLTRLTRRTDLIEEIINDCFWVVWQKAGTFRGDSRVSTWIMG
ISYRCGLKVLRQSGGLDASDDADDGAAAERNHPGINPGDDRELRDWLAKGLARLSADQRLVLELAYTHGHSIEEIAVITQ
APVGTVKARMFHARVKLRNLLPGLAVGGTGTQDIQP

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in heat shock and oxidative stress response; it is believed to control protein processing

COG id: COG1595

COG function: function code K; DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family. ECF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788926, Length=184, Percent_Identity=28.804347826087, Blast_Score=75, Evalue=3e-15,

Paralogues:

None

Copy number: <10 [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000838
- InterPro:   IPR007627
- InterPro:   IPR013249
- InterPro:   IPR014286
- InterPro:   IPR013325
- InterPro:   IPR013324 [H]

Pfam domain/function: PF04542 Sigma70_r2; PF08281 Sigma70_r4_2 [H]

EC number: NA

Molecular weight: Translated: 21780; Mature: 21649

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAHYPDNSHDLALLHAIAAGDRDALATLYRGYHRRLGQFLTRLTRRTDLIEEIINDCFW
CCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVWQKAGTFRGDSRVSTWIMGISYRCGLKVLRQSGGLDASDDADDGAAAERNHPGINPGD
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
DRELRDWLAKGLARLSADQRLVLELAYTHGHSIEEIAVITQAPVGTVKARMFHARVKLRN
CHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LLPGLAVGGTGTQDIQP
HCCCCEECCCCCCCCCC
>Mature Secondary Structure 
TAHYPDNSHDLALLHAIAAGDRDALATLYRGYHRRLGQFLTRLTRRTDLIEEIINDCFW
CCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVWQKAGTFRGDSRVSTWIMGISYRCGLKVLRQSGGLDASDDADDGAAAERNHPGINPGD
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
DRELRDWLAKGLARLSADQRLVLELAYTHGHSIEEIAVITQAPVGTVKARMFHARVKLRN
CHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHH
LLPGLAVGGTGTQDIQP
HCCCCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]