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The map label for this gene is dadA [H]

Identifier: 120611223

GI number: 120611223

Start: 2803798

End: 2805102

Strand: Reverse

Name: dadA [H]

Synonym: Aave_2554

Alternate gene names: 120611223

Gene position: 2805102-2803798 (Counterclockwise)

Preceding gene: 120611224

Following gene: 120611222

Centisome position: 52.4

GC content: 74.25

Gene sequence:

>1305_bases
GTGCCGGCCCAGGCCGACCGGCGGCGCCATGTCGCCGTGATCGGCGCAGGCATCGTGGGCACGGCGTGCGCGATCGAAAT
CCTGCGCACCGGTCGCTCCGTGACGCTGCTCGATCCCCATGCGTCCGGCGGGCCGGAAGCCACGAGCTACGGCAACGCGG
GCTGGCTGTCGTCGCATTCCATCCTTCCACCCTCGAGTCCGGGCATGTGGAAACAGCTGCCAGGCTATCTGCTGGACCCG
CAGGGCCCGCTCACCGTGCGCTGGGGCTACCTGCCCCGCGCCCTGCCCTGGCTCTGGCGCTTCCTGCGCTCCGGGCGCAC
GCCGGCCCGGGTGGCCCGCACCGCGCATGCGCTGCGCCAGCTGCTGCGGGACGCGCCTGCACTGCACGCGCGGCTCGCGG
GTGAAGCCGGCGTGCCCCATCTGGTCGCGCAGCGGGGCCTGCTACACGTCTATCGCTCGCGCGCGGACTTCGAGGCCGAC
GCGCTCGGCTGGCGCCTGCGCGGCGAGGAAGGGATCGCCTTCCGGACACTGGAAGCCGGCGAACTGCGTGCGCAGGAGCC
CGAATTGGCCCCGGCGTATGGCTTCGGCGTGCGCGTTGACGAAGCGGGCCACTGCGCGAACCCGGGCGCCTATCTGGCGG
CACTGGCCGCGCACGCCCAGTCCCGGGGAGCGCGCCACGTCGCCGCACGTGCCACCGGGCTGCGCATCGCATCGGGCCGC
CTGGCCGCCGTCCGGACCGACGCGGGCGACGTGCCCTGCGATGCTGCGGTGATCGCGGCCGGCGCCTATTCCCGGCCCCT
GGCCCGCGACGCGGGCGACCGGGTGTGGCTCGACACCGAACGCGGATACCACGCGATGCTGGACGTGCGTGCCCGGCCGG
GCGAGGCTCCGCCTCCCGGACCGCGCACCTCCACCATGGTGATGGACCGCAAGCTCATCGTCCACCAGATGGAACACGGC
CTGCGCGTGGCGGGTCAGGTGGAGATCGCCGGACTGCAGGCCGCGCCGGACTGGCGCCGCGCGCGCATCCTGCTGGAGCA
TCTGTTCGCGCTCTACCCCGCCCTGCCGCGCCCCGCGCTGGAAAGTGGGGCCCGGTTCTGGATGGGCCGTCGCCCGAGCA
CCAGCGACGGCCTGCCCTGCATCGGCCCCGCGGCCGGCTGCGCGGACGTGGTCCATGCCTACGGGCACGGCCATGTCGGA
CTGGGCTCGTCGGCGCGCACGGGCCGCGTGGTGGCGCAGCTGCTGGACGGCTGCGCACCGGAGATCGACATCGCGCCTTT
CAGCCCCGGGCGCTGGCGACGATAA

Upstream 100 bases:

>100_bases
GTGGACAATGGCCGCACCGGGACGCCCACCGGTTCCATGCCGCGCTGCGATGCCCGTCCCCCTTCCCCCTGATCTTTCCA
GCTCTTCACCTGCATCCCCG

Downstream 100 bases:

>100_bases
TCCGGCGCGCACCGCACGGCGCCCGCCTTCCCGACAACCACCGCCTGCCCGACCGCGCAGGCTTCCGGCCCCGCCCCTTC
ATCTTCCCGCCATGTCCGCT

Product: D-amino-acid dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 433

Protein sequence:

>434_residues
MPAQADRRRHVAVIGAGIVGTACAIEILRTGRSVTLLDPHASGGPEATSYGNAGWLSSHSILPPSSPGMWKQLPGYLLDP
QGPLTVRWGYLPRALPWLWRFLRSGRTPARVARTAHALRQLLRDAPALHARLAGEAGVPHLVAQRGLLHVYRSRADFEAD
ALGWRLRGEEGIAFRTLEAGELRAQEPELAPAYGFGVRVDEAGHCANPGAYLAALAAHAQSRGARHVAARATGLRIASGR
LAAVRTDAGDVPCDAAVIAAGAYSRPLARDAGDRVWLDTERGYHAMLDVRARPGEAPPPGPRTSTMVMDRKLIVHQMEHG
LRVAGQVEIAGLQAAPDWRRARILLEHLFALYPALPRPALESGARFWMGRRPSTSDGLPCIGPAAGCADVVHAYGHGHVG
LGSSARTGRVVAQLLDGCAPEIDIAPFSPGRWRR

Sequences:

>Translated_434_residues
MPAQADRRRHVAVIGAGIVGTACAIEILRTGRSVTLLDPHASGGPEATSYGNAGWLSSHSILPPSSPGMWKQLPGYLLDP
QGPLTVRWGYLPRALPWLWRFLRSGRTPARVARTAHALRQLLRDAPALHARLAGEAGVPHLVAQRGLLHVYRSRADFEAD
ALGWRLRGEEGIAFRTLEAGELRAQEPELAPAYGFGVRVDEAGHCANPGAYLAALAAHAQSRGARHVAARATGLRIASGR
LAAVRTDAGDVPCDAAVIAAGAYSRPLARDAGDRVWLDTERGYHAMLDVRARPGEAPPPGPRTSTMVMDRKLIVHQMEHG
LRVAGQVEIAGLQAAPDWRRARILLEHLFALYPALPRPALESGARFWMGRRPSTSDGLPCIGPAAGCADVVHAYGHGHVG
LGSSARTGRVVAQLLDGCAPEIDIAPFSPGRWRR
>Mature_433_residues
PAQADRRRHVAVIGAGIVGTACAIEILRTGRSVTLLDPHASGGPEATSYGNAGWLSSHSILPPSSPGMWKQLPGYLLDPQ
GPLTVRWGYLPRALPWLWRFLRSGRTPARVARTAHALRQLLRDAPALHARLAGEAGVPHLVAQRGLLHVYRSRADFEADA
LGWRLRGEEGIAFRTLEAGELRAQEPELAPAYGFGVRVDEAGHCANPGAYLAALAAHAQSRGARHVAARATGLRIASGRL
AAVRTDAGDVPCDAAVIAAGAYSRPLARDAGDRVWLDTERGYHAMLDVRARPGEAPPPGPRTSTMVMDRKLIVHQMEHGL
RVAGQVEIAGLQAAPDWRRARILLEHLFALYPALPRPALESGARFWMGRRPSTSDGLPCIGPAAGCADVVHAYGHGHVGL
GSSARTGRVVAQLLDGCAPEIDIAPFSPGRWRR

Specific function: Oxidative deamination of D-amino acids [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Inner Membrane-Bound [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DadA oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787438, Length=430, Percent_Identity=25.3488372093023, Blast_Score=115, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023080
- InterPro:   IPR006076
- InterPro:   IPR006036 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: =1.4.99.1 [H]

Molecular weight: Translated: 46453; Mature: 46321

Theoretical pI: Translated: 10.33; Mature: 10.33

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAQADRRRHVAVIGAGIVGTACAIEILRTGRSVTLLDPHASGGPEATSYGNAGWLSSHS
CCCCCCCCCEEEEEECCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCC
ILPPSSPGMWKQLPGYLLDPQGPLTVRWGYLPRALPWLWRFLRSGRTPARVARTAHALRQ
CCCCCCCCHHHHCCCEEECCCCCEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LLRDAPALHARLAGEAGVPHLVAQRGLLHVYRSRADFEADALGWRLRGEEGIAFRTLEAG
HHHHCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCEEEECCCCCEEEEECCC
ELRAQEPELAPAYGFGVRVDEAGHCANPGAYLAALAAHAQSRGARHVAARATGLRIASGR
CCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCEEEECCC
LAAVRTDAGDVPCDAAVIAAGAYSRPLARDAGDRVWLDTERGYHAMLDVRARPGEAPPPG
EEEEECCCCCCCCCHHHEECCCCCCCHHHCCCCEEEEECCCCCEEEEEEECCCCCCCCCC
PRTSTMVMDRKLIVHQMEHGLRVAGQVEIAGLQAAPDWRRARILLEHLFALYPALPRPAL
CCCCHHHHHHHHHHHHHHCCCEEECEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHH
ESGARFWMGRRPSTSDGLPCIGPAAGCADVVHAYGHGHVGLGSSARTGRVVAQLLDGCAP
HCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCC
EIDIAPFSPGRWRR
CCEECCCCCCCCCC
>Mature Secondary Structure 
PAQADRRRHVAVIGAGIVGTACAIEILRTGRSVTLLDPHASGGPEATSYGNAGWLSSHS
CCCCCCCCEEEEEECCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCCCC
ILPPSSPGMWKQLPGYLLDPQGPLTVRWGYLPRALPWLWRFLRSGRTPARVARTAHALRQ
CCCCCCCCHHHHCCCEEECCCCCEEEEECCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LLRDAPALHARLAGEAGVPHLVAQRGLLHVYRSRADFEADALGWRLRGEEGIAFRTLEAG
HHHHCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHCCEEEECCCCCEEEEECCC
ELRAQEPELAPAYGFGVRVDEAGHCANPGAYLAALAAHAQSRGARHVAARATGLRIASGR
CCCCCCCCCCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCEEEECCC
LAAVRTDAGDVPCDAAVIAAGAYSRPLARDAGDRVWLDTERGYHAMLDVRARPGEAPPPG
EEEEECCCCCCCCCHHHEECCCCCCCHHHCCCCEEEEECCCCCEEEEEEECCCCCCCCCC
PRTSTMVMDRKLIVHQMEHGLRVAGQVEIAGLQAAPDWRRARILLEHLFALYPALPRPAL
CCCCHHHHHHHHHHHHHHCCCEEECEEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHH
ESGARFWMGRRPSTSDGLPCIGPAAGCADVVHAYGHGHVGLGSSARTGRVVAQLLDGCAP
HCCCCEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCC
EIDIAPFSPGRWRR
CCEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]