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The map label for this gene is argK [C]

Identifier: 120611181

GI number: 120611181

Start: 2752048

End: 2753070

Strand: Direct

Name: argK [C]

Synonym: Aave_2512

Alternate gene names: 120611181

Gene position: 2752048-2753070 (Clockwise)

Preceding gene: 120611180

Following gene: 120611182

Centisome position: 51.41

GC content: 72.63

Gene sequence:

>1023_bases
ATGACCGCGCCCCCCCATCCGCTCCTGGCCGGCATCACCGGCGCGCCCGGAGCCGTGCAGCGCCGTGCCATCGCCAAGGC
CATCACGCTGCTCGAATCCACGCGCGCCGACCACCGTGCCCAAGGCGACGCATTGCTCACCGCGCTGCTGCCGCACACCG
GCAAGGCCTTCCGCCTGGGCCTGAGTGGCGTGCCCGGCGTGGGGAAGTCCACCTTCATCGAGGCGCTGGGCCTGCACCTG
ATCGCGCAGGGCCACCGCGTGGCGGTGCTGACCATCGACCCGTCCTCCAGCGTGTCCGGCGGCTCCATCCTGGGCGACAA
GACGCGCATGGAGCGCCTGTCGGTGCATGAGCAGGCCTACATCCGCCCCAGCCCTTCCAGCGGCACGCTGGGCGGCGTGG
CGGAGAAGACGCGCGAGGCCATGCTGGTCTGCGAGGCGGCCGGCTACGACATCGTGATCGTGGAGACGGTGGGCGTCGGC
CAGAGCGAGACCGCCGTGGCGGGCATGACGGACATGTTCGTGCTGATGCAGCTACCCAACGCCGGCGACGACCTGCAGGC
GATCAAGAAGGGCGTGATGGAGATCGCGGACCTGGTGGCGATCAACAAGGCCGACATCGACGCCCATGCCGCGACGCGCG
CCGAGGCGCAGATCACCTCCAGCCTGCGGCTGTTTGGCCAGCACGGCCACCCCGGGCATGCGCGGCACGACTCGGCGCTG
TGGCATCCGCGCGTGCTGCAGATCAGCGCGCTGCAGGGCCGCGGCGTGGACGCCTTCTGGGCGGCGGTGGAGGACTACCG
GCGCGTGCAGTCGGCCAACGGGCATCTCGCGGCGCGGCGCCGGCAGCAGGCGCAGGCCTGGATGTGGGAGCGCATCGACG
CCGGCCTGAAGCAGGCGTTCCGCGCGCAGCCGCAGGTGCGGGCGATGCTGCCGGGCCTGCGCGAGGACGTGCTCGCCGGG
CGCATCGCGGCATCGACCGCGGCACGCAGCCTGCTGCAGGCGGGCGGCTTCGCGCCCCCCTGA

Upstream 100 bases:

>100_bases
TCTACCTGCGCCACGGCTTCCGGCAAGTGGCCGAGGAGCCTTTCGACCTGGAGTACCGCTGGAGCCCGTCGTGGGACGGC
CTGGCTTCGGGAGCGCAGCC

Downstream 100 bases:

>100_bases
CCGGCCCGCGCGGGCCGCGGGCGCCACACGGACATTCGCACAGACAATTCACGGATCGTTGGAAGGAAGACCATGCAAGA
CATCCTGGAACAGCTGGAGA

Product: arginine/ornithine transport system ATPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MTAPPHPLLAGITGAPGAVQRRAIAKAITLLESTRADHRAQGDALLTALLPHTGKAFRLGLSGVPGVGKSTFIEALGLHL
IAQGHRVAVLTIDPSSSVSGGSILGDKTRMERLSVHEQAYIRPSPSSGTLGGVAEKTREAMLVCEAAGYDIVIVETVGVG
QSETAVAGMTDMFVLMQLPNAGDDLQAIKKGVMEIADLVAINKADIDAHAATRAEAQITSSLRLFGQHGHPGHARHDSAL
WHPRVLQISALQGRGVDAFWAAVEDYRRVQSANGHLAARRRQQAQAWMWERIDAGLKQAFRAQPQVRAMLPGLREDVLAG
RIAASTAARSLLQAGGFAPP

Sequences:

>Translated_340_residues
MTAPPHPLLAGITGAPGAVQRRAIAKAITLLESTRADHRAQGDALLTALLPHTGKAFRLGLSGVPGVGKSTFIEALGLHL
IAQGHRVAVLTIDPSSSVSGGSILGDKTRMERLSVHEQAYIRPSPSSGTLGGVAEKTREAMLVCEAAGYDIVIVETVGVG
QSETAVAGMTDMFVLMQLPNAGDDLQAIKKGVMEIADLVAINKADIDAHAATRAEAQITSSLRLFGQHGHPGHARHDSAL
WHPRVLQISALQGRGVDAFWAAVEDYRRVQSANGHLAARRRQQAQAWMWERIDAGLKQAFRAQPQVRAMLPGLREDVLAG
RIAASTAARSLLQAGGFAPP
>Mature_339_residues
TAPPHPLLAGITGAPGAVQRRAIAKAITLLESTRADHRAQGDALLTALLPHTGKAFRLGLSGVPGVGKSTFIEALGLHLI
AQGHRVAVLTIDPSSSVSGGSILGDKTRMERLSVHEQAYIRPSPSSGTLGGVAEKTREAMLVCEAAGYDIVIVETVGVGQ
SETAVAGMTDMFVLMQLPNAGDDLQAIKKGVMEIADLVAINKADIDAHAATRAEAQITSSLRLFGQHGHPGHARHDSALW
HPRVLQISALQGRGVDAFWAAVEDYRRVQSANGHLAARRRQQAQAWMWERIDAGLKQAFRAQPQVRAMLPGLREDVLAGR
IAASTAARSLLQAGGFAPP

Specific function: May have GTPase activity. May also bind and hydrolyze ATP. May function as chaperone [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=326, Percent_Identity=48.159509202454, Blast_Score=295, Evalue=3e-80,
Organism=Escherichia coli, GI1789285, Length=269, Percent_Identity=50.5576208178439, Blast_Score=273, Evalue=1e-74,
Organism=Caenorhabditis elegans, GI71994271, Length=326, Percent_Identity=41.4110429447853, Blast_Score=252, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI71994275, Length=280, Percent_Identity=42.5, Blast_Score=235, Evalue=2e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129
- InterPro:   IPR003593 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 35947; Mature: 35815

Theoretical pI: Translated: 10.09; Mature: 10.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPPHPLLAGITGAPGAVQRRAIAKAITLLESTRADHRAQGDALLTALLPHTGKAFRLG
CCCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHCCCCCEEEEC
LSGVPGVGKSTFIEALGLHLIAQGHRVAVLTIDPSSSVSGGSILGDKTRMERLSVHEQAY
CCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEECCHHHHHHHHHHHHHE
IRPSPSSGTLGGVAEKTREAMLVCEAAGYDIVIVETVGVGQSETAVAGMTDMFVLMQLPN
ECCCCCCCCCCHHHHHHHHHEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHEEECCC
AGDDLQAIKKGVMEIADLVAINKADIDAHAATRAEAQITSSLRLFGQHGHPGHARHDSAL
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
WHPRVLQISALQGRGVDAFWAAVEDYRRVQSANGHLAARRRQQAQAWMWERIDAGLKQAF
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RAQPQVRAMLPGLREDVLAGRIAASTAARSLLQAGGFAPP
HCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TAPPHPLLAGITGAPGAVQRRAIAKAITLLESTRADHRAQGDALLTALLPHTGKAFRLG
CCCCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHCCCCCEEEEC
LSGVPGVGKSTFIEALGLHLIAQGHRVAVLTIDPSSSVSGGSILGDKTRMERLSVHEQAY
CCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCEECCHHHHHHHHHHHHHE
IRPSPSSGTLGGVAEKTREAMLVCEAAGYDIVIVETVGVGQSETAVAGMTDMFVLMQLPN
ECCCCCCCCCCHHHHHHHHHEEEEECCCCCEEEEEEECCCCCCHHHHHHHHHHHEEECCC
AGDDLQAIKKGVMEIADLVAINKADIDAHAATRAEAQITSSLRLFGQHGHPGHARHDSAL
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
WHPRVLQISALQGRGVDAFWAAVEDYRRVQSANGHLAARRRQQAQAWMWERIDAGLKQAF
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RAQPQVRAMLPGLREDVLAGRIAASTAARSLLQAGGFAPP
HCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8421698; 11259647 [H]