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The map label for this gene is czcB [H]

Identifier: 120611174

GI number: 120611174

Start: 2741757

End: 2743007

Strand: Direct

Name: czcB [H]

Synonym: Aave_2505

Alternate gene names: 120611174

Gene position: 2741757-2743007 (Clockwise)

Preceding gene: 120611173

Following gene: 120611175

Centisome position: 51.22

GC content: 68.03

Gene sequence:

>1251_bases
ATGCAAAAAAATACCGATACTTCCACGGGCAAGGTCCAGGCCAGCCATGTGGTTCTCGTCATCGTCCTGGTCGTCCTGAC
CGCCGTCGCCGGGTTCTTCATCCTCCGCCCCGCGAAACCCGGTGGCGCCGATGGGTACGCGGCCGACGCGCGGCCGGCGG
ACGCGCATGGCGAGGGCCATGCCGGGGAACCTGAGGAACATGGCCGCGAGGAGGGCCATGAAAAGGGCCGAATCGCCTTC
TCGGACGAGCAGTTCAAGTCCTCCGGCGTGGCCGTCGAAACGAGCGGGCCCGGAGTGATCGAGACCCGCACCCGGCTGCC
CGGTGAAATCCGGTTCAACGAGGACCGCACGGCGCACGTGGTCCCCCGCGTCGCCGGTGTCGTCGAAAGCGTCGGCGCCG
ATCTGGGGCAGCACGTACGCAAGGGCCAGGTTCTGGCCGTCATCTCCAGCGTGGCGCTGTCCGAGCAGCGCAGCGAACTG
CTGGCCGCACAGAAGCGCCTGGCCCTGGCCCGTACCACCGCGGACCGCGAGCGCAGGCTGTTCCAGGACAAGATCTCGGC
CCAGCAGGACGTCCTGCAGGCAGAGCAGGTTCTGCACGAGGCGGAGATCGCCGTCGCGAACGCCAGCCGGAAGCTGCGGG
CACTGGGAGCGGCCGCCAGCTCCGGCGATCTTGCGCGGTTCGAGCTGCGGGCGCCCTTCGATGGCATGGTGGTCGAAAAG
CACATTGCGCTGGGCGAGTCGGTGAAGGAAGACGCGAATGTGTTCACCATCTCCGACCTCTCCACGGTGTGGGCCCAGAT
CAATGTGACGGCGGCCAACCTGCCGCTGGTGAAGGTCGGGGAGCCCGTGGCCATCCAGGCAACAGGCTTCCAGCATGAGG
CGACCGGCAAGGTGTCGTATGTCGGCGCGCTCATCGGGGAGCAGACGCGCACCGCCACGGCACGCGCGACGCTGCCGAAT
CCCGAGATGGCGTGGCGTCCCGGATTGTTCGTCACGGTGGAACTGGTCACCGGCAAGGCCGAGGCGCCTGTCACCGTGGC
CGCGGACGCCATCCAGATGGTGGAGGGCCGCCCGACCGTGTATGCGAAGGTGGACGGCGGATTCGAGCCGAGACCCGTCA
AGACCGGCCGCTCGGATGGCCGGAGCATCGAGATCCTCGACGGACTGGCCGCCGGCACTGCCTATGCCGGCAGGGGCAGC
TTCGTCGTCAAGGCACAGCAGGGCAAGGGCTCCTCGGGCCACGAACACTGA

Upstream 100 bases:

>100_bases
CGCTGCTCGATACCTACCGCGCCGCAGCCGAACTGGAGCGCCTGCTCCACGTCACGGACGCGTCTTCCACCCTCCTGAAT
CCTTCCAGGCCCTGAACGCC

Downstream 100 bases:

>100_bases
GAAGCACCATGTTCGAGCGAATCATCCATTTCTCCATTGCCCATCGCTGGCTCGTGATGCTCGCCGTCGCGGGCATGGCC
GCACTGGGCATCTACAACTA

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 416

Protein sequence:

>416_residues
MQKNTDTSTGKVQASHVVLVIVLVVLTAVAGFFILRPAKPGGADGYAADARPADAHGEGHAGEPEEHGREEGHEKGRIAF
SDEQFKSSGVAVETSGPGVIETRTRLPGEIRFNEDRTAHVVPRVAGVVESVGADLGQHVRKGQVLAVISSVALSEQRSEL
LAAQKRLALARTTADRERRLFQDKISAQQDVLQAEQVLHEAEIAVANASRKLRALGAAASSGDLARFELRAPFDGMVVEK
HIALGESVKEDANVFTISDLSTVWAQINVTAANLPLVKVGEPVAIQATGFQHEATGKVSYVGALIGEQTRTATARATLPN
PEMAWRPGLFVTVELVTGKAEAPVTVAADAIQMVEGRPTVYAKVDGGFEPRPVKTGRSDGRSIEILDGLAAGTAYAGRGS
FVVKAQQGKGSSGHEH

Sequences:

>Translated_416_residues
MQKNTDTSTGKVQASHVVLVIVLVVLTAVAGFFILRPAKPGGADGYAADARPADAHGEGHAGEPEEHGREEGHEKGRIAF
SDEQFKSSGVAVETSGPGVIETRTRLPGEIRFNEDRTAHVVPRVAGVVESVGADLGQHVRKGQVLAVISSVALSEQRSEL
LAAQKRLALARTTADRERRLFQDKISAQQDVLQAEQVLHEAEIAVANASRKLRALGAAASSGDLARFELRAPFDGMVVEK
HIALGESVKEDANVFTISDLSTVWAQINVTAANLPLVKVGEPVAIQATGFQHEATGKVSYVGALIGEQTRTATARATLPN
PEMAWRPGLFVTVELVTGKAEAPVTVAADAIQMVEGRPTVYAKVDGGFEPRPVKTGRSDGRSIEILDGLAAGTAYAGRGS
FVVKAQQGKGSSGHEH
>Mature_416_residues
MQKNTDTSTGKVQASHVVLVIVLVVLTAVAGFFILRPAKPGGADGYAADARPADAHGEGHAGEPEEHGREEGHEKGRIAF
SDEQFKSSGVAVETSGPGVIETRTRLPGEIRFNEDRTAHVVPRVAGVVESVGADLGQHVRKGQVLAVISSVALSEQRSEL
LAAQKRLALARTTADRERRLFQDKISAQQDVLQAEQVLHEAEIAVANASRKLRALGAAASSGDLARFELRAPFDGMVVEK
HIALGESVKEDANVFTISDLSTVWAQINVTAANLPLVKVGEPVAIQATGFQHEATGKVSYVGALIGEQTRTATARATLPN
PEMAWRPGLFVTVELVTGKAEAPVTVAADAIQMVEGRPTVYAKVDGGFEPRPVKTGRSDGRSIEILDGLAAGTAYAGRGS
FVVKAQQGKGSSGHEH

Specific function: CzcA and CzcB together would act in zinc efflux nearly as effectively as the complete czc efflux system (CzcABC). The CzcB protein is thought to funnel zinc cations to the CzcA transport protein [H]

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87081796, Length=308, Percent_Identity=25.6493506493506, Blast_Score=62, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005695
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 43884; Mature: 43884

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKNTDTSTGKVQASHVVLVIVLVVLTAVAGFFILRPAKPGGADGYAADARPADAHGEGH
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCC
AGEPEEHGREEGHEKGRIAFSDEQFKSSGVAVETSGPGVIETRTRLPGEIRFNEDRTAHV
CCCCHHHHHHCCCCCCCEEECCHHHHCCCEEEECCCCCEEEECCCCCCEEEECCCCCHHH
VPRVAGVVESVGADLGQHVRKGQVLAVISSVALSEQRSELLAAQKRLALARTTADRERRL
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FQDKISAQQDVLQAEQVLHEAEIAVANASRKLRALGAAASSGDLARFELRAPFDGMVVEK
HHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHCCCCCCCEEEEEECCCCCCEEEHH
HIALGESVKEDANVFTISDLSTVWAQINVTAANLPLVKVGEPVAIQATGFQHEATGKVSY
HHHHCCCHHCCCCEEEEECHHEEEEEEEEEEECCCEEECCCCEEEEECCCCCCCCCCCEE
VGALIGEQTRTATARATLPNPEMAWRPGLFVTVELVTGKAEAPVTVAADAIQMVEGRPTV
HHHHHCCCHHCCEEEECCCCCCCCCCCCEEEEEEEEECCCCCCEEEHHHHHHHHCCCCEE
YAKVDGGFEPRPVKTGRSDGRSIEILDGLAAGTAYAGRGSFVVKAQQGKGSSGHEH
EEEECCCCCCCCCCCCCCCCCEEEEECCHHHCCEECCCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MQKNTDTSTGKVQASHVVLVIVLVVLTAVAGFFILRPAKPGGADGYAADARPADAHGEGH
CCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCCCCCCC
AGEPEEHGREEGHEKGRIAFSDEQFKSSGVAVETSGPGVIETRTRLPGEIRFNEDRTAHV
CCCCHHHHHHCCCCCCCEEECCHHHHCCCEEEECCCCCEEEECCCCCCEEEECCCCCHHH
VPRVAGVVESVGADLGQHVRKGQVLAVISSVALSEQRSELLAAQKRLALARTTADRERRL
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FQDKISAQQDVLQAEQVLHEAEIAVANASRKLRALGAAASSGDLARFELRAPFDGMVVEK
HHHHHHHHHHHHHHHHHHHHHHHEEECCHHHHHHHHCCCCCCCEEEEEECCCCCCEEEHH
HIALGESVKEDANVFTISDLSTVWAQINVTAANLPLVKVGEPVAIQATGFQHEATGKVSY
HHHHCCCHHCCCCEEEEECHHEEEEEEEEEEECCCEEECCCCEEEEECCCCCCCCCCCEE
VGALIGEQTRTATARATLPNPEMAWRPGLFVTVELVTGKAEAPVTVAADAIQMVEGRPTV
HHHHHCCCHHCCEEEECCCCCCCCCCCCEEEEEEEEECCCCCCEEEHHHHHHHHCCCCEE
YAKVDGGFEPRPVKTGRSDGRSIEILDGLAAGTAYAGRGSFVVKAQQGKGSSGHEH
EEEECCCCCCCCCCCCCCCCCEEEEECCHHHCCEECCCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8829543 [H]